Extragenital lichen sclerosus arising in tattooed skin

Lichen sclerosus (LSc) is a chronic inflammatory condition commonly affecting the anogenital area, with extragenital involvement seen in less than 1%–20% of cases. Concomitant extragenital and genital LSc is extremely rare in male patients. The Koebner phenomenon is a recognised feature of LSc; here we present a rare case of extragenital LSc occurring in tattooed skin.

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Pilonidal Cyst of the Penis Mimicking Carcinoma

Case Reports in Urology ◽

10.1155/2013/984757 ◽

2013 ◽

Vol 2013 ◽

pp. 1-2

Author(s):

Luigi Cormio ◽

Francesca Sanguedolce ◽

Paolo Massenio ◽

Giuseppe Di Fino ◽

Giuseppe Carrieri

Keyword(s):

Differential Diagnosis ◽

Pilonidal Sinus ◽

Rare Case ◽

Subcutaneous Tissue ◽

Sinus Tract ◽

Penile Carcinoma ◽

Inflammatory Condition ◽

Pilonidal Cyst ◽

Chronic Inflammatory Condition

Pilonidal sinus is a long-standing chronic inflammatory condition consisting of a sinus tract from the skin-lined orifice extending into subcutaneous tissue, with hairs attached to the wall of the tract and projecting outside of the opening. Penile location is rare, and differential diagnosis with severe balanoposthitis, epidermal cysts, and neoplasms can be difficult. We report a rare case of pilonidal cyst located between coronal sulcus and prepuce which, due to its ulcerated aspect and absence of a tract with projecting hairs, simulated a penile carcinoma.

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High Frequency of Obesity in Acne Keloidalis Nuchae Patients: A Hypothesis from a Brazilian Study

Skin Appendage Disorders ◽

10.1159/000509203 ◽

2020 ◽

Vol 6 (6) ◽

pp. 374-378

Author(s):

Andrea Mizuno Matsunaga ◽

Violeta Duarte Tortelly ◽

Carla Jorge Machado ◽

Ludmila Ribeiro Pedrosa ◽

Daniel Fernandes Melo

Keyword(s):

Metabolic Syndrome ◽

High Frequency ◽

Related Factor ◽

Obese Patients ◽

Inflammatory Condition ◽

Chronic Inflammatory Condition ◽

General Physicians ◽

Male Patients ◽

Per Se ◽

The Relationship

Acne keloidalis nuchae (AKN) is a chronic inflammatory condition that almost exclusively affects the occipital and nape areas. Although not completely understood, its etiopathogenesis seems to be multifactorial, including association with metabolic syndrome (MetS). Despite being commonly seen in patients with MetS, obesity per se as a possible related factor for AKN has yet to be studied. The aim of this study was to evaluate the relationship between obesity and AKN in a series of patients. Eight male patients, with a median age of 38 years (range 15–48), were included. Overweight/obesity was found in 8/8 (100%), with median BMI of 32.2 (range 27.7–43.85 kg/m<sup>2</sup>), including 2 patients with class 3 obesity. We hypothesize adipose tissue accumulation in the nape, the only moving part of the scalp, leads to redundant skin folds, more friction, and inflammation, triggering AKN. This paper highlights the possible relationship between AKN and overweight/obesity, hypothesizing a mechanism for their contribution to the etiopathogenesis of this scalp disorder. To the best of our knowledge, this is the first study focused specifically in this association. While general physicians should pay attention to the appearing of AKN in overweight/obese patients, dermatologists must be aware that AKN patients should be assessed beyond the skin.

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Faculty Opinions recommendation of Histological evidence of urethral involvement in male patients with genital lichen sclerosus: a preliminary report.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.723580716.793513189 ◽

2016 ◽

Author(s):

Christopher Chapple ◽

Nadir Osman

Keyword(s):

Preliminary Report ◽

Lichen Sclerosus ◽

Histological Evidence ◽

Male Patients

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TNF-Alpha Inhibitors and Ustekinumab for the Treatment of Psoriasis: Therapeutic Utility in the Era of IL-17 and IL-23 Inhibitors

Journal of Psoriasis and Psoriatic Arthritis ◽

10.1177/24755303211047479 ◽

2022 ◽

pp. 247553032110474

Author(s):

Julie J. Hong ◽

Edward K. Hadeler ◽

Megan L. Mosca ◽

Nicholas D. Brownstone ◽

Tina Bhutani ◽

...

Keyword(s):

Treatment Resistance ◽

Risk Patient ◽

Tnf Alpha ◽

Inflammatory Condition ◽

Biologic Therapies ◽

Malignancy Risk ◽

Patient Demographics ◽

The Past ◽

Chronic Inflammatory Condition ◽

Patient Subgroups

Psoriasis is a chronic inflammatory condition for which eleven FDA-approved biologic therapies are approved. Over the past decade, studies have documented the higher efficacy of IL-17 and IL-23 inhibitors for the treatment of psoriasis compared to the TNF-alpha inhibitors and ustekinumab, an IL-12/23 inhibitor. Despite this, there remains an important role for the use of TNF-alpha inhibitors and ustekinumab in the treatment of psoriasis. Here, we review how considerations of infection and malignancy risk, patient demographics, treatment resistance, and comorbidities may make certain TNF-alpha inhibitors or ustekinumab an excellent choice for therapy in particular patient subgroups.

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Cardiopulmonary Manifestations of Ankylosing Spondylitis

International Journal of Rheumatology ◽

10.1155/2011/728471 ◽

2011 ◽

Vol 2011 ◽

pp. 1-6 ◽

Cited By ~ 33

Author(s):

Mahnaz Momeni ◽

Nora Taylor ◽

Mahsa Tehrani

Keyword(s):

Ankylosing Spondylitis ◽

Cardiac Dysfunction ◽

Spontaneous Pneumothorax ◽

Pulmonary Complications ◽

Inflammatory Condition ◽

Stepwise Approach ◽

Conduction Disturbances ◽

Chronic Inflammatory Condition ◽

Pulmonary Manifestations ◽

Valve Diseases

Ankylosing spondylitis is a chronic inflammatory condition that usually affects young men. Cardiac dysfunction and pulmonary disease are well-known and commonly reported extra-articular manifestation, associated with ankylosing spondylitis (AS). AS has also been reported to be specifically associated with aortitis, aortic valve diseases, conduction disturbances, cardiomyopathy and ischemic heart disease. The pulmonary manifestations of the disease include fibrosis of the upper lobes, interstitial lung disease, ventilatory impairment due to chest wall restriction, sleep apnea, and spontaneous pneumothorax. They are many reports detailing pathophysiology, hypothesized mechanisms leading to these derangements, and estimated prevalence of such findings in the AS populations. At this time, there are no clear guidelines regarding a stepwise approach to screen these patients for cardiovascular and pulmonary complications.

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Sickle cell disease: a chronic inflammatory condition

Medical Hypotheses ◽

10.1054/mehy.2000.1310 ◽

2001 ◽

Vol 57 (1) ◽

pp. 46-50 ◽

Cited By ~ 38

Author(s):

J.A.B. Chies ◽

N.B. Nardi

Keyword(s):

Sickle Cell Disease ◽

Sickle Cell ◽

Inflammatory Condition ◽

Cell Disease ◽

Chronic Inflammatory Condition

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Not all colonic growths are malignant

BMJ Case Reports ◽

10.1136/bcr-2019-229515 ◽

2019 ◽

Vol 12 (7) ◽

pp. e229515

Author(s):

Geethu Rachel Iype ◽

Sasank Kalipatnapu ◽

Dipti Masih ◽

Gigi Varghese

Keyword(s):

Inflammatory Condition ◽

Chronic Inflammatory Condition ◽

Xanthogranulomatous Inflammation

We present the case of a 34-year-old woman who was diagnosed to have adenocarcinoma of the caecum based on the clinical, radiological, histopathological and intraoperative findings. However, postoperative histopathology showed only features of xanthogranulomatous inflammation without any evidence of malignancy. This benign chronic inflammatory condition could present as a histological surprise. It is important for both surgeons and pathologists alike to be aware of this.

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