scholarly journals Reducing time to angiography and hospital stay for patients with high-risk non-ST-elevation acute coronary syndrome: retrospective analysis of a paramedic-activated direct access pathway

BMJ Open ◽  
2016 ◽  
Vol 6 (6) ◽  
pp. e010428
Author(s):  
S Koganti ◽  
N Patel ◽  
A Seraphim ◽  
T Kotecha ◽  
M Whitbread ◽  
...  
2015 ◽  
pp. 592-597 ◽  
Author(s):  
Burcak Kilickiran Avci ◽  
Baris Ikitimur ◽  
Ozge Ozden Tok ◽  
Murat Cimci ◽  
Emre Erturk ◽  
...  

Heart ◽  
2021 ◽  
pp. heartjnl-2020-318778
Author(s):  
Thomas A Kite ◽  
Andrew Ladwiniec ◽  
J Ranjit Arnold ◽  
Gerry P McCann ◽  
Alastair J Moss

Non-ST-elevation acute coronary syndrome (NSTE-ACS) comprises a broad spectrum of disease ranging from unstable angina to myocardial infarction. International guidelines recommend a routine invasive strategy for managing patients with NSTE-ACS at high to very high-risk, supported by evidence of improved composite ischaemic outcomes as compared with a selective invasive strategy. However, accurate diagnosis of NSTE-ACS in the acute setting is challenging due to the spectrum of non-coronary disease that can manifest with similar symptoms. Heterogeneous clinical presentations and limited uptake of risk prediction tools can confound physician decision-making regarding the use and timing of invasive coronary angiography (ICA). Large proportions of patients with suspected NSTE-ACS do not require revascularisation but may unnecessarily undergo ICA with its attendant risks and associated costs. Advances in coronary CT angiography and cardiac MRI have prompted evaluation of whether non-invasive strategies may improve patient selection, or whether tailored approaches are better suited to specific subgroups. Future directions include (1) better understanding of risk stratification as a guide to investigation and therapy in suspected NSTE-ACS, (2) randomised clinical trials of non-invasive imaging versus standard of care approaches prior to ICA and (3) defining the optimal timing of very early ICA in high-risk NSTE-ACS.


2008 ◽  
Vol 101 (5) ◽  
pp. 573-578 ◽  
Author(s):  
Eduardo Missel ◽  
Gary S. Mintz ◽  
Stephane G. Carlier ◽  
Koichi Sano ◽  
Jie Qian ◽  
...  

2007 ◽  
Vol 8 (3) ◽  
pp. 9
Author(s):  
Manes Erlichman ◽  
Paulo Cesar Gobert Damasceno Campos ◽  
Jose Marconi Almeida de Sousa ◽  
Marcos Damião Candido Ferreira ◽  
Rudyney Eduardo Uchoa de Azevedo ◽  
...  

2021 ◽  
Vol 73 (1) ◽  
Author(s):  
Dileep Kumar ◽  
Arti Ashok ◽  
Tahir Saghir ◽  
Naveedullah Khan ◽  
Bashir Ahmed Solangi ◽  
...  

Abstract Background The aim of this study was to determine the predictive value of the Global Registry of Acute Coronary Events (GRACE) score for predicting in-hospital and 6 months mortality after non-ST elevation acute coronary syndrome (NSTE-ACS). Results In this observational study, 300 patients with NSTE-ACS of age more than 30 years were included; 16 patients died during the hospital stay (5.3%). Of 284 patients at 6 months assessment, 10 patients died (3.5%), 240 survived (84.5%), and 34 were lost to follow-up (12%) respectively. In high risk category, 10.5% of the patients died within hospital stay and 11.8% died within 6 months (p = 0.001 and p = 0.013). In univariate analysis, gender, diabetes mellitus, family history, smoking, and GRACE score were significantly associated with in-hospital mortality whereas age, obesity, dyslipidemia, and GRACE were significantly associated with 6 months mortality. After adjustment, diabetes mellitus, family history, and GRACE score remained significantly associated with in-hospital mortality (p ≤ 0.05) and age remained significantly associated with 6 months mortality. Conclusion GRACE risk score has good predictive value for the prediction of in-hospital mortality and 6 months mortality among patients with NSTE-ACS.


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