Impact of resilience on health in older adults: a cross-sectional analysis from the International Mobility in Aging Study (IMIAS)

ObjectivesSelf-rated health (SRH) is a predictor of objective health measures, including mortality and morbidity. The link between resilience and SRH among the elderly is unclear. We aim to examine whether resilience aligns with SRH and, secondarily, whether resilience can override the negative health consequences of adverse childhood experiences (ACE).Design and settingWe use 2012, 2014 and 2016 data from the International Mobility in Aging Study, a longitudinal cohort study that collects survey and biophysical data from Albania, Brazil, Colombia and Canada. The main independent variables were resilience and ACE (social and economic).ParticipantsCommunity-dwelling 65–74 year olds (in 2012) were recruited through primary care registers. The sample size of the study was 1506.Primary outcomeThe outcome measure was SRH.ResultsWe found that sex, site, economic ACE, current income sufficiency, current depressive symptoms, current physical function and current resilience were associated with current SRH. In regression analyses, we showed that the association between ACE and SRH disappeared once factors such as sex, site, income, depression, physical health and resilience were considered.ConclusionsThe association between resilience and health poses a compelling argument for building resilience throughout life.

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Prevalence of Impaired Kidney Function in the German Elderly: Results from the Berlin Aging Study II (BASE-II)

Gerontology ◽

10.1159/000454831 ◽

2017 ◽

Vol 63 (3) ◽

pp. 201-209 ◽

Cited By ~ 4

Author(s):

Maximilian König ◽

Maik Gollasch ◽

Ilja Demuth ◽

Elisabeth Steinhagen-Thiessen

Keyword(s):

Risk Factors ◽

Older Adults ◽

Chronic Kidney Disease ◽

Kidney Disease ◽

The Elderly ◽

Community Dwelling ◽

Structured Interviews ◽

Cross Sectional ◽

Increased Risk ◽

Aging Study

Background: In aging populations with an ever-growing burden of risk factors such as obesity, diabetes, and hypertension, chronic kidney disease (CKD) is on the rise. However, little is known about its exact prevalence among elderly adults, and often albuminuria is not included in the definition of CKD. Moreover, novel equations for the estimated glomerular filtration rate (eGFR) have recently emerged, which have not been applied comprehensively to older adults. Data on CKD awareness among the elderly are sparse. Objectives: To determine the prevalence of CKD among older adults by eGFR and albumin/creatinine ratio (ACR), compare the performance of 6 established and novel eGFR formulas, explore risk factors, and determine the awareness of CKD in a large cohort of community-dwelling elderly from Germany. Methods: A total of 1,628 subjects from the Berlin Aging Study II (BASE-II) were included in this analysis (mean age 68.7 years; 51.2% female). Extensive cross-sectional data on sociodemographics, lifestyle, medication, and diagnoses were inquired during structured interviews and a medical examination, and blood and urine parameters were measured. Results: In all, 77.1% of the subjects had hypertension, 12.4% had diabetes, and 18.3% were obese. The prevalence of CKD strongly depended on the eGFR equations used: 25.4% (full age spectrum [FAS] equation), 24.6% (Berlin Initiative Study), 23.1% (Lund-Malmö revised), 19.3% (Cockcroft-Gault), 16.4% (Chronic Kidney Disease-Epidemiology Collaboration [CKD-EPI]), and 14.7% (Modification of Diet in Renal Disease [MDRD]). Of the subjects with an eGFRFAS <60 mL/min/1.73 m2 and/or an ACR >30 mg/g, only 3.9% were aware of having CKD. Polypharmacy, age, BMI, coronary artery disease, non-HDL cholesterol, and female sex were independently associated with CKD. Conclusions: CKD is prevalent among older adults in Germany, but awareness is low. The FAS equation detects higher rates of CKD than MDRD and CKD-EPI, which are most widely used at present. Also, when CKD is defined based on eGFR and albuminuria, considerably more people are identified than by eGFR alone. Finally, polypharmacy is associated with an increased risk for CKD in the elderly.

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A Frailty Index from Next-of-Kin Data: A Cross-Sectional Analysis from the Mexican Health and Aging Study

BioMed Research International ◽

10.1155/2017/6069374 ◽

2017 ◽

Vol 2017 ◽

pp. 1-6 ◽

Cited By ~ 4

Author(s):

Mario Ulises Pérez-Zepeda ◽

Matteo Cesari ◽

María Fernanda Carrillo-Vega ◽

Guillermo Salinas-Escudero ◽

Pamela Tella-Vega ◽

...

Keyword(s):

Older Adults ◽

Frailty Index ◽

Community Dwelling ◽

Next Of Kin ◽

Cross Sectional ◽

Cross Sectional Analysis ◽

Aging Study ◽

The Mean ◽

Number Of Visits ◽

Sectional Analysis

Objectives. To construct a frailty index from next-of-kin information of the last year of life of community-dwelling 50 years old or older adults and test its association with health services utilization. Methods. Cross-sectional analysis from next-of-kin data available from the last wave of the Mexican Health and Aging Study (MHAS). Measurements. Along with descriptive statistics, the frailty index (FI) was tested in regression models to assess its association with adverse outcomes previous to death: number of hospitalized days in the previous year and number of visits to a physician in the previous year, in unadjusted and adjusted models. Results. From a total of 2,649 individuals the mean of age was 74.8 (±11.4) and 56.3% (n = 1,183) were women. The mean of the FI was of 0.279 (±SD 0.131, R = 0.0–0.738) and distribution was biased to the right. There was a significant association (p < 0.001) between the FI and number of hospitalized days (β = 45.7, 95% CI 36.1–55.4, p < 0.001) and for the number of visits to a physician (β = 25.93, 95% CI 19.27–32.6, p < 0.001) both models adjusted for age and sex. Conclusion. The FI constructed with next-of-kin data showed similar characteristics to similar indexes of older adults. It was independently associated with health care use.

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Age at First Birth, Parity and History of Hysterectomy Are Associated to Frailty Status: Cross-Sectional Analysis from the International Mobility in Aging Study -Imias

Journal of Cross-Cultural Gerontology ◽

10.1007/s10823-018-9360-x ◽

2018 ◽

Vol 33 (4) ◽

pp. 337-354 ◽

Cited By ~ 2

Author(s):

Cristiano S. Gomes ◽

Catherine M. Pirkle ◽

Juliana F. S. Barbosa ◽

Afshin Vafaei ◽

Saionara M. A. Câmara ◽

...

Keyword(s):

Age At First Birth ◽

International Mobility ◽

First Birth ◽

Cross Sectional ◽

Frailty Status ◽

Cross Sectional Analysis ◽

Aging Study ◽

History Of ◽

Sectional Analysis ◽

Birth Parity

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Early maternal age at first birth is associated with chronic diseases and poor physical performance in older age: cross-sectional analysis from the International Mobility in Aging Study

BMC Public Health ◽

10.1186/1471-2458-14-293 ◽

2014 ◽

Vol 14 (1) ◽

Cited By ~ 50

Author(s):

Catherine M Pirkle ◽

◽

Ana Carolina Patrício de Albuquerque Sousa ◽

Beatriz Alvarado ◽

Maria-Victoria Zunzunegui

Keyword(s):

Chronic Diseases ◽

Physical Performance ◽

Maternal Age ◽

Older Age ◽

Age At First Birth ◽

International Mobility ◽

First Birth ◽

Cross Sectional ◽

Aging Study ◽

Sectional Analysis

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Associations of Adverse Childhood Experiences with Frailty in Older Adults: A Cross-Sectional Analysis of Data from the Canadian Longitudinal Study on Aging

Gerontology ◽

10.1159/000520327 ◽

2021 ◽

pp. 1-10

Author(s):

Oxana Mian ◽

Laura N. Anderson ◽

Daniel W. Belsky ◽

Andrea Gonzalez ◽

Jinhui Ma ◽

...

Keyword(s):

Older Adults ◽

Longitudinal Study ◽

Adverse Childhood Experiences ◽

Parental Death ◽

Well Being ◽

Cross Sectional ◽

Childhood Experiences ◽

Cross Sectional Analysis ◽

Adverse Childhood ◽

Sectional Analysis

Introduction: Frailty in older adults, characterized by a decline in multiple physiological systems and increasing vulnerability to loss of independence, disability, and death, is a public health priority in developed countries. Etiology of frailty extends across the lifespan and may begin in early life, but empirical evidence for this association is scarce. In this study, we examined whether adverse childhood experiences (ACEs) are associated with frailty in later life. Methods: We conducted a cross-sectional analysis of data for a population-based sample of 27,748 adults aged 45–85 years from the Canadian Longitudinal Study on Aging. The frailty index (FI) was computed with 76 health-related characteristics of physical and cognitive performance, self-rated health, chronic conditions, visual and hearing ability, activities of daily living, and well-being. Self-reported exposure to ACEs included physical, emotional, and sexual abuse, neglect, and witnessing intimate partner violence prior age of 16 and parental death, divorce, and living with a family member with mental illness prior age of 18. Generalized linear regression models with gamma error distribution and identity link function, adjusted for age and sex, were used to examine associations of each ACE type and the number of ACE types (0, 1, 2, or 3+) reported by an individual with FI. All models were adjusted for income, education, smoking, and alcohol consumption in sensitivity analysis. Results: Individuals exposed to ACEs had elevated levels of FI (mean = 0.13, SD = 0.09) than those unexposed, with the largest difference observed for neglect (B [95% CI]: 0.05 [0.04, 0.06]) and the smallest for parental death and divorce (0.015 [0.01,0.02]). The ACE count was associated with frailty in a graded manner, with the FI difference reaching 0.04 [0.037, 0.044] for participants exposed to 3+ ACE types. The association between ACEs and frailty tended to be stronger for women than men and for men aged 45–64 years than older men. Conclusions: Our study supports previous studies showing that exposure to ACEs is associated with frailty in adults. Our findings suggest that screening for ACEs involving childhood maltreatment may be useful for identifying individuals at risk of frailty and prevention of ACEs may have long-term benefits for healthy aging.

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