scholarly journals Multimorbidity in cardiovascular disease and association with life satisfaction: a Chinese national cross-sectional study

BMJ Open ◽  
2020 ◽  
Vol 10 (12) ◽  
pp. e042950
Author(s):  
Guihao Liu ◽  
Yunlian Xue ◽  
Yuanhui Liu ◽  
Sheng Wang ◽  
Qingshan Geng
Keyword(s):  
Cardiovascular Disease ◽  
Life Satisfaction ◽  
Kidney Disease ◽  
Chronic Diseases ◽  
Cross Sectional Study ◽  
Multiple Chronic Conditions ◽  
Sectional Study ◽  
Cross Sectional ◽  
Logistic Regression Models ◽  
Nationally Representative

BackgroundThe coexistence of multiple chronic conditions is very common in cardiovascular disease (CVD). However, the prevalence of CVD multimorbidity in China and its influence on life satisfaction have not been reported. This study aimed to investigate the proportions of 12 chronic comorbid diseases in CVD and the associations of multimorbidity with life satisfaction in patients with CVD.MethodsWe conducted a cross-sectional study in a nationally representative sample of 3478 participants with CVD aged 45 years or more who participated in the China Health and Retirement Longitudinal Study 2015. Correlations of multimorbidity with 12 chronic diseases in CVD and life satisfaction were investigated using logistic regression models, after adjusting for 12 covariates.ResultsThe proportion of multimorbidity among participants with CVD was 93.3% (89.4% for middle-aged adults and 95.4% for older adults; 92.9% for men and 93.5% for women). The proportion of participants with CVD multimorbidity who were dissatisfied with life was 11.2%, significantly higher than those without any chronic diseases (χ2=5.147, p=0.023). Life satisfaction in patients with CVD decreased with increased number of comorbidities (χ2=45.735, p<0.001). Kidney disease (OR=1.933, 95% CI: 1.483 to 2.521), memory-related diseases (MRDs) (OR=1.695, 95% CI: 1.149 to 2.501) and dyslipidaemia (OR=1.346, 95% CI: 1.048 to 1.729) were significantly associated with reduced life satisfaction when adjusting for 12 covariates.ConclusionsIn this nationally representative cross-sectional study, life satisfaction was reduced by multimorbidity of CVD. Kidney disease had the greatest influence on life satisfaction in patients with CVD, followed by dyslipidaemia and MRDs. Our study emphasises the importance of preventing of chronic diseases in adults with CVD.

Self-Esteem as a Mediator between Life Satisfaction and Depression among Cardiovascular Disease Patients

2021 ◽  
pp. 105477382110300
Author(s):  
Zeying Qin ◽  
Songli Mei ◽  
Tingting Gao ◽  
Leilei Liang ◽  
Chuanen Li ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Life Satisfaction ◽  
Cardiovascular Diseases ◽  
Self Esteem ◽  
Cross Sectional Study ◽  
Third Grade ◽  
Sectional Study ◽  
Cross Sectional

This study explores the association between life satisfaction and depression among patients with cardiovascular diseases and whether this association is mediated by self-esteem. A cross-sectional study was conducted in a third-grade hospital. We examined 300 patients with cardiovascular diseases with a mean age of 62.00 years (females, 133). Life satisfaction was associated with depression. Adding self-esteem to the model weakened the strength of the association between the two. Moreover, 34.2% of the effect of life satisfaction on depression could be explained by self-esteem. We found that self-esteem could totally explain the effect of life satisfaction on depression among patients with cardiovascular diseases.

P1134HIGH PREVALENCE OF SLEEP-DISODERED BREATHING AND ITS ASSOCIATION WITH RENAL FUNCTION AMONG CHRONIC KIDNEY DISEASE PATIENTS (CKD1-5,HD AND PD) : A CROSS-SECTIONAL STUDY

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Kanji Ota ◽  
Yosuke Nakayama ◽  
Yokota Yunosuke ◽  
Goh Kodama ◽  
Sakuya Itou ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Extracellular Fluid ◽  
Cross Sectional Study ◽  
Oxygen Desaturation ◽  
Sectional Study ◽  
Cross Sectional ◽  
Desaturation Index ◽  
Oxygen Desaturation Index

Abstract Background and Aims Sleep-disordered breathing (SDB) is known as a novel risk factor for cardiovascular disease, and one of five adults suffer from SDB in general population. In non-dialysis chronic kidney disease (CKD) and hemodialysis (HD) patients, a high prevalence of SDB has been reported due to the excess accumulation of extracellular fluid. However, precise prevalence and associated factors of SDB in patients with peritoneal dialysis (PD) has not been known. This cross-sectional study aimed to investigate the prevalence and determinant factors associated with SDB in patients with CKD. Method This was a single-center retrospective cohort study recruited 334 patients with CKD stages 1-3a, 3b-5, HD, and PD enrolled from 2018 to 2020. All patients were hospitalized and received our CKD educational program, and did not have sleep complaints. The diagnosis and assessment of the severity of SDB were evaluated using PULSOX-Me300 and SAS2100 systems. The 3% oxygen desaturation index and SpO2 were measured during sleep. SDB was defined as 3% oxygen desaturation index (ODI)&gt;15.0 and SpO2&lt;92% in this study. Results Proportion of the patients with CKD1-3a, CKD3b-5, HD, and PD were 28%, 53%, 11%, and 8%, respectively. Thirty-one% of the patients were diagnosed with SBD in all CKD patients. In a generalized linear model, 3% ODI&gt;15.0 and SpO2&lt;92% were significantly correlated with apnea hypopnea index (p&lt;0.05, r=0.87 and p&lt;0.05, r=-0.45, respectively). Further, it became clear that the proportion of 3%ODI&gt;15 and SpO2&lt;92% was significantly higher in PD patients (50%) than in other CKD patients. Furthermore, 3% ODI was significantly correlated with BMI and HDL cholesterol levels in PD patients (p&lt;0.05, r=0.67 and p&lt;0.05, r=-0.54, respectively). Conclusion We reported for the first time that the prevalence of SDB was very high and that the severity of SDB was significantly associated with BMI in patients with PD. These findings suggest that the extracellular fluid overload and excess glucose exposure due to PD fluid might accelerate SDB in patients with PD. Further clinical studies are needed to determine whether PD-associated SDB might influence the development of cardiovascular disease in CKD patients.

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