PTH-116 Time to Achieve Competency in Lower Gastrointestinal Polypectomy in The United Kingdom, A Retrospective Analysis

Gut ◽  
2016 ◽  
Vol 65 (Suppl 1) ◽  
pp. A276-A277 ◽  
Author(s):  
A Rajendran ◽  
S Thomas-Gibson ◽  
P Bassett ◽  
P Dunckley ◽  
N Sevdalis ◽  
...  
Keyword(s):  
United Kingdom ◽  
Retrospective Analysis ◽  
The United Kingdom

Opicapone and Levodopa-Carbidopa Intestinal Gel Infusion: The Way Forward Towards Cost Savings for Healthcare Systems?

2020 ◽  
Vol 10 (4) ◽  
pp. 1535-1539
Author(s):  
Valentina Leta ◽  
Daniel J. van Wamelen ◽  
Anna Sauerbier ◽  
Shelley Jones ◽  
Miriam Parry ◽  
...  
Keyword(s):  
United Kingdom ◽  
Side Effects ◽  
Retrospective Analysis ◽  
Dose Reduction ◽  
Clinical Care ◽  
Cost Savings ◽  
Healthcare Systems ◽  
Methyl Transferase ◽  
The United Kingdom ◽  
Daily Dose

Combined catechol-O-methyl-transferase-inhibition and Levodopa-Carbidopa intestinal gel (LCIG) infusion has the potential to reduce LCIG daily dose and the costs of this therapy. In this retrospective analysis, we report on Parkinson’s disease (PD) patients on LCIG with concomitant Opicapone. In 11 patients, the introduction of Opicapone led to LCIG daily dose being reduced by 24.8% (p = 0.05) without any significant worsening of dyskinesia. Three patients withdrew from Opicapone due to side effects or inefficacy. LCIG daily dose reduction could lead to cost savings of £142,820.63/year in the United Kingdom while maintaining clinical care.

Is failure to provide venous thromboprophylaxis negligent?

2007 ◽  
Vol 22 (4) ◽  
pp. 186-191 ◽  
Author(s):  
J R H Scurr ◽  
J H Scurr
Keyword(s):  
Risk Factors ◽  
Risk Assessment ◽  
United Kingdom ◽  
Venous Thromboembolism ◽  
Retrospective Analysis ◽  
Expert Witness ◽  
Surgical Patients ◽  
Vascular Surgeon ◽  
The United Kingdom ◽  
Is Failure

Objectives: To report the outcome of 100 consecutive medicolegal claims referred to one of the authors (1990–2003) following the development of venous thromboembolism (VTE) in surgical patients. Methods: A retrospective analysis of the experience of a vascular surgeon acting as an expert witness in the United Kingdom. Results: Prophylaxis had been provided to 43 claimants with risk factors, who, unfortunately, still developed a VTE and alleged negligence. Twenty-nine claims involved patients who had not received prophylaxis because they were at low risk. In 25/28 claims where no prophylaxis was provided, despite identifiable VTE risk factors, the claim was successful. Claimants who developed a VTE that had been managed incorrectly were successful whether they had received prophylaxis or not. Settlement amounts, where disclosed, are reported. Conclusions: Failure to perform a risk assessment and to provide appropriate venous thromboprophylaxis in surgical patients is considered negligent. Clinicians looking after all hospitalized patients who are not assessing their patients' risk for VTE and/or not providing appropriate prophylaxis are at risk of being accused of negligence.

Sa1227 Time to Achieve Competency in Lower Gastrointestinal Polypectomy in the United Kingdom, a Retrospective Analysis

2016 ◽  
Vol 83 (5) ◽  
pp. AB262
Author(s):  
Arun Rajendran ◽  
Siwan Thomas-Gibson ◽  
Paul Bassett ◽  
Paul Dunckley ◽  
Nick Sevdalis ◽  
...  
Keyword(s):  
United Kingdom ◽  
Retrospective Analysis ◽  
The United Kingdom

Epidemiology and cost of herpes zoster and post-herpetic neuralgia in the United Kingdom

2008 ◽  
Vol 137 (1) ◽  
pp. 38-47 ◽  
Author(s):  
A. GAUTHIER ◽  
J. BREUER ◽  
D. CARRINGTON ◽  
M. MARTIN ◽  
V. RÉMY
Keyword(s):  
General Practice ◽  
United Kingdom ◽  
Herpes Zoster ◽  
Retrospective Analysis ◽  
General Practice Research Database ◽  
Practice Research ◽  
Research Database ◽  
Post Herpetic Neuralgia ◽  
The United Kingdom ◽  
The Uk

SUMMARYRecent information on epidemiology and management of herpes zoster (HZ) and post-herpetic neuralgia (PHN), a painful complication of HZ, is scarce. The objective of this study was to document the burden of HZ and PHN in the United Kingdom. This retrospective analysis of the UK General Practice Research Database aimed to estimate HZ incidence and proportion of HZ patients developing PHN and to assess management costs in immunocompetent individuals aged ⩾50 years. A cohort of 27 225 HZ patients was selected, corresponding to an incidence of 5·23/1000 person-years. Respectively 19·5% and 13·7% of patients developed PHN at least 1 and 3 months after HZ diagnosis. Mean direct cost was £103 per HZ patient and £341 and £397 per PHN episode (1- and 3-month definition respectively). Both HZ and PHN costs increased markedly with pain severity. This study confirms that HZ and PHN are frequent and costly diseases in the United Kingdom.

Growth hormone increases rate of pubertal maturation

1990 ◽  
Vol 122 (3) ◽  
pp. 414-416 ◽  
Author(s):  
F. Darendeliler ◽  
P. C. Hindmarsh ◽  
M. A. Preece ◽  
L. Cox ◽  
C. G. D. Brook
Keyword(s):  
Growth Hormone ◽  
United Kingdom ◽  
Longitudinal Study ◽  
Retrospective Analysis ◽  
Growth And Development ◽  
Skeletal Maturity ◽  
Age At Onset ◽  
Contributory Factor ◽  
Gh Treatment ◽  
The United Kingdom

Abstract We have performed a retrospective analysis of the pubertal parameters of 134 children with isolated GH insufficiency on GH treatment and compared them to the standards of Tanner and to a recent longitudinal study of growth and development in the United Kingdom. The age at onset of puberty (13.0 years in boys, 12.1 years in girls) was found to be significantly delayed (Mann-Whitney p<0.001), but duration of puberty (1.5 years in both sexes) was shortened (Kolgomarov-Smirnov p<0.01). Skeletal maturity at the onset of puberty was not advanced excluding this as a contributory factor. There was no association between dose of GH administered and the pubertal parameters. The results suggest that GH accelerates the pubertal process.

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