scholarly journals EPV077/#472 Clinical implications of computed tomography-based, artificial intelligence-driven sarcopenia and body composition change during primary treatment in early cervical cancer

2021 ◽  
Author(s):  
SI Kim ◽  
Q Han ◽  
M Lee ◽  
J-W Kim
Keyword(s):  
Artificial Intelligence ◽  
Computed Tomography ◽  
Cervical Cancer ◽  
Body Composition ◽  
Primary Treatment ◽  
Clinical Implications ◽  
Composition Change ◽  
Body Composition Change ◽  
Early Cervical Cancer

scholarly journals Impact of Computed Tomography-Based, Artificial Intelligence-Driven Volumetric Sarcopenia on Survival Outcomes in Early Cervical Cancer

2021 ◽  
Vol 11 ◽  
Author(s):  
Qingling Han ◽  
Se Ik Kim ◽  
Soon Ho Yoon ◽  
Taek Min Kim ◽  
Hyun-Cheol Kang ◽  
...  
Keyword(s):  
Artificial Intelligence ◽  
Skeletal Muscle ◽  
Cervical Cancer ◽  
Lumbar Vertebra ◽  
Primary Treatment ◽  
Survival Outcomes ◽  
Poor Prognostic Factor ◽  
Body Composition Change ◽  
Early Cervical Cancer ◽  
The Impact

The purpose of this study was to investigate the impact of sarcopenia and body composition change during primary treatment on survival outcomes in patients with early cervical cancer. We retrospectively identified patients diagnosed with 2009 International Federation of Gynecology and Obstetrics stage IB1-IIA2 cervical cancer who underwent primary radical hysterectomy between 2007 and 2019. From pre-treatment CT scans (n = 306), the skeletal muscle area at the third lumbar vertebra (L3) and the waist skeletal muscle volume were measured using an artificial intelligence-based tool. These values were converted to the L3 and volumetric skeletal muscle indices by normalization. We defined L3 and volumetric sarcopenia using 39.0 cm2/m2 and the first quartile (Q1) value, respectively. From pre- and post-treatment CT scan images (n = 192), changes (%) in waist skeletal muscle and fat volumes were assessed. With the use of Cox regression models, factors associated with progression-free survival (PFS) and overall survival (OS) were analyzed. Between the L3 sarcopenia and non-sarcopenia groups, no differences in PFS and OS were observed. In contrast, volumetric sarcopenia was identified as a poor prognostic factor for PFS (adjusted hazard ratio [aHR], 1.874; 95% confidence interval [CI], 1.028–3.416; p = 0.040) and OS (aHR, 3.001; 95% CI, 1.016–8.869; p = 0.047). During primary treatment, significant decreases in waist skeletal muscle (median, −3.9%; p < 0.001) and total fat (median, −5.3%; p < 0.001) were observed. Of the two components, multivariate analysis revealed that the waist fat gain was associated with worse PFS (aHR, 2.007; 95% CI, 1.009–3.993; p = 0.047). The coexistence of baseline volumetric sarcopenia and waist fat gain further deteriorated PFS (aHR, 2.853; 95% CI, 1.257–6.474; p = 0.012). In conclusion, baseline volumetric sarcopenia might be associated with poor survival outcomes in patients with early cervical cancer undergoing primary RH. Furthermore, sarcopenia patients who gained waist fat during primary treatment were at a high risk of disease recurrence.

Multimodal measurement of body composition change with diet- and exercise-induced weight loss in obese women

2011 ◽  
Vol 35 (2) ◽  
pp. 204-205
Author(s):  
A.R. Josse ◽  
S.A. Atkinson ◽  
M.A. Tarnopolsky ◽  
H. Azizian ◽  
J.K.G. Kramer ◽  
...  
Keyword(s):  
Weight Loss ◽  
Body Composition ◽  
Obese Women ◽  
Composition Change ◽  
Body Composition Change ◽  
Diet And Exercise ◽  
Exercise Induced

P237 The impact of body composition change on neo-adjuvant chemotherapy for breast cancer patients

The Breast ◽  
2015 ◽  
Vol 24 ◽  
pp. S106-S107
Author(s):  
T. Iwase ◽  
T. Sangai ◽  
E. Ishigami ◽  
J. Sakakibara ◽  
K. Fujisaki ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Body Composition ◽  
Adjuvant Chemotherapy ◽  
Cancer Patients ◽  
Composition Change ◽  
Breast Cancer Patients ◽  
Body Composition Change ◽  
Neo Adjuvant Chemotherapy ◽  
The Impact

scholarly journals Same-Day Vs Consecutive-Day Precision Error of Dual-Energy X-Ray Absorptiometry for Interpreting Body Composition Change in Resistance-Trained Athletes

2019 ◽  
Vol 22 (1) ◽  
pp. 104-114 ◽  
Author(s):  
Adam J. Zemski ◽  
Karen Hind ◽  
Shelley E. Keating ◽  
Elizabeth M. Broad ◽  
Damian J. Marsh ◽  
...  
Keyword(s):  
Body Composition ◽  
Dual Energy ◽  
Composition Change ◽  
Precision Error ◽  
X Ray ◽  
Body Composition Change

Evaluating patterns of weight and body composition change among college women

2015 ◽  
Vol 17 ◽  
pp. 157-162 ◽  
Author(s):  
Mackenzie C. Kelly ◽  
Janet D. Latner
Keyword(s):  
Body Composition ◽  
College Women ◽  
Composition Change ◽  
Body Composition Change

Characterising the impact of body composition change during neoadjuvant chemotherapy for pancreatic cancer

Pancreatology ◽  
2019 ◽  
Vol 19 (6) ◽  
pp. 850-857 ◽  
Author(s):  
Oonagh M. Griffin ◽  
Sinead N. Duggan ◽  
Ronan Ryan ◽  
Raymond McDermott ◽  
Justin Geoghegan ◽  
...  
Keyword(s):  
Pancreatic Cancer ◽  
Body Composition ◽  
Neoadjuvant Chemotherapy ◽  
Composition Change ◽  
Body Composition Change ◽  
The Impact

Exercise Intensity Does Not Effect Body Composition Change in Untrained, Moderately Overfat Women

1995 ◽  
Vol 95 (6) ◽  
pp. 661-665 ◽  
Author(s):  
MAJ ANN GREDIAGIN ◽  
MILDRED CODY ◽  
JEFFREY RUPP ◽  
DAN BENARDOT ◽  
ROBIN SHERN
Keyword(s):  
Body Composition ◽  
Exercise Intensity ◽  
Composition Change ◽  
Body Composition Change
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