scholarly journals EPV245/#230 Increasing incidence of ovarian and uterine carcinosarcoma: a United States cancer statistics study

2021 ◽  
Author(s):  
I Tunnage ◽  
C-I Liao ◽  
D Lewis ◽  
MA Caesar ◽  
A Chan ◽  
...  
Keyword(s):  
United States ◽  
Uterine Carcinosarcoma ◽  
Cancer Statistics

Racial disparities in high-risk uterine cancer histologic subtypes: A United States Cancer Statistics study

2021 ◽  
Vol 161 (2) ◽  
pp. 470-476
Author(s):  
Mary Kathryn Abel ◽  
Cheng-I Liao ◽  
Chloe Chan ◽  
Danny Lee ◽  
Atharva Rohatgi ◽  
...  
Keyword(s):  
United States ◽  
High Risk ◽  
Racial Disparities ◽  
Uterine Cancer ◽  
Cancer Statistics ◽  
Histologic Subtypes

scholarly journals Trends of uterine carcinosarcoma in the United States

2018 ◽  
Vol 29 (2) ◽  
Author(s):  
Koji Matsuo ◽  
Malcolm S. Ross ◽  
Hiroko Machida ◽  
Erin A. Blake ◽  
Lynda D. Roman
Keyword(s):  
United States ◽  
The United States ◽  
Uterine Carcinosarcoma

scholarly journals Trends in the Incidence of Pancreatic Adenocarcinoma in All 50 United States Examined Through an Age-Period-Cohort Analysis

2020 ◽  
Vol 4 (4) ◽  
Author(s):  
Wilson L da Costa ◽  
Abiodun O Oluyomi ◽  
Aaron P Thrift
Keyword(s):  
United States ◽  
Pancreatic Ductal Adenocarcinoma ◽  
Cohort Analysis ◽  
The United States ◽  
Incidence Rates ◽  
Ductal Adenocarcinoma ◽  
Birth Cohorts ◽  
Men And Women ◽  
Cancer Statistics ◽  
Incidence Trends

Abstract Background Pancreatic ductal adenocarcinoma is a major contributor to cancer-related mortality in the United States. We aimed to investigate trends in incidence rates from all 50 states from 2001 to 2016, overall and by race, sex, and state and using age-period-cohort analyses. Methods Age-adjusted incidence rates and trends in adults aged 35 years and older were calculated using data from the US Cancer Statistics registry. We used joinpoint regression to compute annual percent changes (APC) and average annual percent changes. We also analyzed incidence trends by age groups and birth cohorts through age-period-cohort modeling. Results Age-standardized incidence rates increased by 1.23% (95% confidence interval [CI] = 0.92% to 1.54%) annually between 2001 and 2008 but were stable between 2008 and 2016 (APC = 0.11%, 95% CI = -0.13% to 0.35%). APCs and inflection points were no different for men and women. Rates increased statistically significantly among non-Hispanic whites (NHW) and non-Hispanic blacks between 2001 and 2007 and between 2001 and 2008, respectively, but, in later years, rates increased slowly among NHWs (APC = 0.36%, 95% CI = 0.12% to 0.60%), and were stable among non-Hispanic blacks (APC = -0.40%, 95% CI = -0.89% to 0.10%). The number of states with age-standardized incidence rates no less than 20.4 per 100 000 increased from 16 in 2001–2003 to 40 by 2015–2016. We found a strong birth cohort effect in both men and women and increasing rates among successive birth cohorts of NHWs. Conclusions The incidence of pancreatic ductal adenocarcinoma has consistently increased in the United States, albeit at slower rates recently. We observed notable increases among NHWs and in some states in the central and southern part of the country.

Trends of cancer associated with modifiable behavior in the U.S.: Is there a difference based on age, gender, or race?

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 1542-1542
Author(s):  
Cheng-I Liao ◽  
Michelle Ann P. Caesar ◽  
Chloe Chan ◽  
Michael Richardson ◽  
Daniel Stuart Kapp ◽  
...  
Keyword(s):  
United States ◽  
Physical Inactivity ◽  
Hispanic Women ◽  
The United States ◽  
Female Breast Cancer ◽  
Annual Percent Change ◽  
Projection Model ◽  
Cancer Statistics ◽  
Modifiable Factors ◽  
Social Cause

1542 Background: To examine trends in modifiable behaviorally related cancers among men and women in the United States. Methods: Data were obtained from the United States Cancer Statistics (USCS) database for all cancers diagnosed between 2001 and 2017. Alcohol-associated cancers, HPV-associated, obesity-associated, physical inactivity-associated, and tobacco-associated were defined using ICD-O-3 site codes. SEER*Stat 8.3.8 and Joinpoint regression program 4.8.0.1 were used to calculate the trends of associated cancers expressed per 100,000. Results: In 2017 the incidence of cancers in women associated with alcohol, smoking and obesity were 168/100,000, 134/100,000 and 121/100,000 respectively. Based on analysis of trends of women from 2001 to 2017, alcohol, smoking and physical inactivity related cancers decreased with an annual percent change (APC -0.51%, -0.96%, -0.92% respectively, p < 0.001). However, there was no significant change in obesity, HPV, or post menopausal female breast cancer related cancers (APC: 0.07%, 0.09%, -0.08% respectively, p = 0.303, 0.181, 0.569). Based on age, in women less than 65, rates of obesity related cancers are increasing. Based on racial groups, all rates of cancer associated with modifiable factors are decreasing, however Hispanic women have an increasing rate of obesity related cancers (APC 0.46%, p < 0.001). When examining differences in region, all rates of cancer are decreasing or unchanged except the south has an increasing rate of obesity related cancer (APC 0.28%, p < 0.001). Using a projection model, obesity will become the highest incidence cancer in Hispanic women by 2035, surpassing alcohol and tobacco. In 2017 the incidence of cancers in men associated with tobacco, obesity, and alcohol were 209/100,000, 111/100,000 and 81/100,000 respectively. Based on analysis of trends in men alcohol, smoking, physical inactivity and obesity related cancers decreased (APC -1.42%, -1.59%, -3.15%, -0.41% respectively, p < 0.001). HPV related cancers have increased (APC 2.36%, p < 0.001). In men less than 60 years old, the rates of obesity related cancers are increasing. Using a prediction model, obesity is predicted to surpass tobacco as the most common social cause of cancer in 2020 for men 35-39, 2024 in men 40-44 and in 2030 in men 45-49. Conclusions: In women, most modifiable factors associated with cancer are decreasing except in obesity and HPV related cancers. In men, these rates of cancer are decreasing except HPV related cancers. However, rates of obesity related cancers are on the rise in Hispanic women and younger men. Obesity is set to become the major modifiable factor for many associated cancers.

Young patients with cancer related to modifiable behaviors in the United States: What can we learn from them?

2021 ◽  
Vol 39 (15_suppl) ◽  
pp. 10560-10560
Author(s):  
John Chan ◽  
Michelle Ann P. Caesar ◽  
Chloe Chan ◽  
Michael Richardson ◽  
Daniel Stuart Kapp ◽  
...  
Keyword(s):  
United States ◽  
Physical Inactivity ◽  
Hispanic Women ◽  
Young Patients ◽  
The United States ◽  
Annual Percent Change ◽  
Projection Model ◽  
Cancer Statistics ◽  
Modifiable Factors ◽  
Younger Men

10560 Background: We proposed to examine trends in modifiable behaviorally related cancers among younger men and women in the United States. Methods: Alcohol-associated cancers, HPV-associated, obesity-associated, physical inactivity-associated, and tobacco-associated were defined using ICD-O-3 site codes. From 2001 and 2017, registry data were obtained from the United States Cancer Statistics database. SEER*Stat 8.3.8 and Joinpoint regression program 4.8.0.1 were used to calculate the trends of associated cancers expressed per 100,000. Results: Of the young women (ages 20-49 years) the incidence of cancers in 2017 associated with alcohol, smoking and obesity were 89/100,000, 43/100,000 and 64/100,000 respectively. Based on analysis of trends of women from 2001 to 2017, obesity, physical inactivity and alcohol related cancers increased with an annual percent change (APC 2.31%, 1.67%, 0.46%, p < 0.001). Using a projection model, in Hispanic women, obesity related cancers will become the highest incidence cancers by 2035, surpassing alcohol and physical inactivity. Of the young men (ages 20-49 years) the incidence of cancers in 2017 associated with alcohol, obesity, and tobacco were 23/100,000, 36/100,000 and 44/100,000 respectively. On trends analysis, obesity, physical inactivity, and alcohol related cancers have increased (APC 2.0%, 1.65%, 0.17%, p < 0.001, p < 0.001, p = 0.044), whereas tobacco-related cancers are decreasing with an APC of -0.44% (p < 0.001). When examining different regions, the highest APC for obesity and physical inactivity related cancers was 2.43% in the Midwest (p < 0.001). Using a prediction model, obesity is predicted to surpass alcohol and physical inactivity related cancers for men 20-49 years old by 2035. Conclusions: In women, most modifiable factors associated with cancer are increasing except in HPV related cancers. In men, these rates of cancer are increasing except in tobacco related cancers. However, rates of obesity related cancers are on the rise in Hispanic women and younger men in southern U.S. regions. Obesity is projected to become the major modifiable factor for many associated cancers.

Impact of socioeconomic status on the incidence and mortality of multiple myeloma in the United States.

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e13595-e13595
Author(s):  
Ibrahim Omore ◽  
Richard Stephen Sheppard ◽  
Stefani Beale
Keyword(s):  
United States ◽  
Multiple Myeloma ◽  
Socioeconomic Status ◽  
Social Deprivation ◽  
Age Groups ◽  
Population Data ◽  
The United States ◽  
Level Of Education ◽  
Cancer Statistics ◽  
Incidence And Mortality

e13595 Background: Socioeconomic deprivation is known to be associated with poorer survival among cancer patients, but studies has not shown the impacts of socioeconomic status on the Incidence and mortality of multiple myeloma. This article analyzed the socioeconomic inequalities in United States Multiple Myeloma Incidence and Mortality. Methods: We examined national trends in the Incidence and Survival disparities among patients with Multiple Myeloma by race/ethnicity and socioeconomic status. A retrospective cohort of Multiple Myeloma patients diagnosed from 2012 to 2016 belonging to all age groups, genders, income per household and level of education was identified from Surveillance, Epidemiology and End results database, United States Cancer Statistics and Population data from Census Bureau. Results: We found mortality to be higher among African American and in States with low median household income and low level of education. In conclusion our study shows a strong correlation between social deprivation and decreased survival in patients with Multiple Myeloma in all age groups. Also we found that Asians and Pacific Islanders seems to have higher survival compare to African Americans and Other ethnicities. Conclusions: Census‐based socioeconomic measures such as poverty and education levels could serve as important surveillance tools for monitoring trends in cancer‐related health inequalities and targeting interventions.

Incidence of Testicular Cancer in the United States, 1999-2004

2009 ◽  
Vol 4 (4) ◽  
pp. 353-360 ◽  
Author(s):  
Julie S. Townsend ◽  
Lisa C. Richardson ◽  
Robert R. German
Keyword(s):  
United States ◽  
Testicular Cancer ◽  
Alaska Native ◽  
Germ Cell Tumors ◽  
White Men ◽  
The United States ◽  
Incidence Rates ◽  
Testicular Germ Cell ◽  
Cancer Statistics ◽  
Hispanic White

Testicular cancer is rare but primarily affects young men. To characterize the current incidence of testicular cancer in the United States, U.S. Cancer Statistics data from 1999 through 2004 were examined. Age-adjusted (2000 U.S. standard) incidence rates were calculated for seminoma and nonseminoma testicular germ cell tumors (TGCTs). Hispanic men had the largest increase in incidence rates for nonseminomas, followed by non-Hispanic White men (annual percentage change of 3.2% and 1.9%, respectively, p < .05). Nonseminomas peaked at a younger age for Hispanic, American Indian/Alaska Native (AIAN), and Asian/Pacific Islander (API) men. Whereas 9.6% of TGCTs were diagnosed at a distant stage in non-Hispanic White men, more Hispanic (16.1%), Black (13.8%), AIAN (16.8%), and API (14.9%) men with TGCTs were diagnosed with distant stage. Monitoring incidence rates for rare cancers by race/ethnicity has improved with national population-based cancer registry coverage. Disparities in diagnosis stage have implications for effective treatment of TGCTs.

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