P39 Changes in loneliness and social isolation over time in adults aged over 50: the English Longitudinal Study of Ageing

2016 ◽  
Vol 70 (Suppl 1) ◽  
pp. A70.2-A70
Author(s):  
NK Valtorta ◽  
M Kanaan ◽  
S Gilbody ◽  
B Hanratty
2017 ◽  
Vol 75 (1) ◽  
pp. 114-124 ◽  
Author(s):  
Snorri Bjorn Rafnsson ◽  
Martin Orrell ◽  
Eleonora d’Orsi ◽  
Eef Hogervorst ◽  
Andrew Steptoe

Abstract Objectives Social relationships are important for the maintenance of cognitive function at older ages, with both objective features of social networks and perceived social connections (loneliness) being relevant. There is limited evidence about how different aspects of social experience predict diagnosed dementia. Methods The sample comprised 6,677 dementia-free individuals at baseline (2004) from the English Longitudinal Study of Ageing. Baseline information on loneliness, number of close relationships, marital status, and social isolation (contact with family and friends and participation in organizations) was analyzed in relation to incident dementia over an average 6.25 years using Cox regression, controlling for potential confounding factors. Results Two hundred twenty participants developed dementia during follow-up. In multivariable analyses, dementia risk was positively related to greater loneliness (hazard ratio 1.40, 95% confidence interval 1.09–1.80, p = .008), and inversely associated with number of close relationships (p < .001) and being married (p = .018). Sensitivity analyses testing for reverse causality and different criteria for diagnosing dementia confirmed the robustness of these findings. There was no association with social isolation. Discussion Dementia risk is associated with loneliness and having fewer close relationships in later life. The underlying mechanisms remain to be elucidated, but efforts to enhance older peoples’ relationship quality may be relevant to dementia risk.


2021 ◽  
Vol 5 (Supplement_1) ◽  
pp. 173-174
Author(s):  
Fereshteh Mehrabi ◽  
François Béland

Abstract Social isolation and frailty are global public health issues that may lead to poor health outcomes. We tested the two following hypotheses: 1) changes in social isolation and frailty are associated with adverse health outcomes over two years, 2) the associations between social isolation and health vary across different levels of frailty. We estimated a series of latent growth models to test our hypotheses using data from the FRéLE longitudinal study among 1643 Canadian community-dwelling older adults aged 65 years and over. Missing data were handled by pattern mixture models with the assumption of missing not at random. We measured social isolation through social participation, social networks, and social support from different social ties. We assessed frailty using Fried’s criteria. Our results revealed that higher frailty at baseline was associated with a higher rate of comorbidity, depression, and cognitive decline over two years. Less social participation at baseline was associated with comorbidity, depression, and changes in cognitive decline. Less social support from friends, children, partner, and family at baseline was associated with comorbidity, cognitive decline, and changes in depression. Fewer contacts with grandchildren were related to cognitive decline over time. The associations of receiving less support from partner with depression and participating less in social activities with comorbidity, depression, and cognitive decline were higher among frail or prefrail than robust older adults over time. This longitudinal study suggests that intimate connectedness and social participation may ameliorate health status in frail older populations, highlighting the importance of age-friendly city policies.


2018 ◽  
Vol 25 (13) ◽  
pp. 1387-1396 ◽  
Author(s):  
Nicole K Valtorta ◽  
Mona Kanaan ◽  
Simon Gilbody ◽  
Barbara Hanratty

Background There is increasing evidence of an association between social relationships and morbidity in general, and cardiovascular disease in particular. However, recent syntheses of the evidence raise two important questions: is it the perceived quality or the more objective quantity of relationships that matters most; and what are the implications of changes in relationships over time? In this study, we investigate the cumulative effects of loneliness and social isolation on incident cardiovascular disease. Design A secondary analysis of prospective follow-up data from the English Longitudinal Study of Ageing (ELSA). Methods To assess the association between social isolation or loneliness and incident cardiovascular disease, lagged values of exposure to loneliness and isolation were treated as time-varying variables in discrete time survival models controlling for potential confounders and established cardiovascular disease risk factors. Results A total of 5397 men and women aged over 50 years were followed up for new fatal and non-fatal diagnoses of heart disease and stroke between 2004 and 2010. Over a mean follow-up period of 5.4 years, 571 new cardiovascular events were recorded. We found that loneliness was associated with an increased risk of cardiovascular disease (odds ratio 1.27, 95% confidence interval 1.01–1.57). Social isolation, meanwhile, was not associated with disease incidence. There was no evidence of a cumulative effect over time of social relationships on cardiovascular disease risk. Conclusions Loneliness is associated with an increased risk of developing coronary heart disease and stroke, independently of traditional cardiovascular disease risk factors. Our findings suggest that primary prevention strategies targeting loneliness could help to prevent cardiovascular disease.


2019 ◽  
Vol 3 (Supplement_1) ◽  
pp. S190-S191
Author(s):  
Jessica G Abell ◽  
Jessica Abell ◽  
Dorina Cadar ◽  
David J Llewellyn ◽  
Andrew Steptoe

Abstract Globally the numbers of older people who live alone and those who may experience certain risk factors have risen. In this study, we aim to examine associations between social isolation and loneliness with different domains of cognitive impairment. Data are from the English Longitudinal Study of Ageing (ELSA). Social isolation and loneliness were measured in 2012-2013 and cognition in 2017-2018, using the Harmonised Cognitive Assessment Protocol (HCAP) in 1,200 men and women aged ≥65 years. General cognitive impairment was measured using the Mini-Mental Status Examination (MMSE); memory was assessed using the CERAD word list, attention & speed using the Symbol-Digit Modalities Test and executive function by a number series test. Loneliness, measured using the UCLA scale, was associated with a higher risk of neurocognitive impairment (MMSE<24), lower memory scores, poorer attention and executive function. However, social isolation was only found only to be associated with lower levels of memory.


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