scholarly journals The prevalence of potentially inappropriate medication prescribing in elderly patients with chronic kidney disease

2013 ◽  
Vol 89 (1051) ◽  
pp. 247-250 ◽  
Author(s):  
Sarah Amy Jones ◽  
Sunil Bhandari
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Elderly Patients ◽  
Inappropriate Medication ◽  
Potentially Inappropriate Medication ◽  
Medication Prescribing

Chronic kidney disease (CKD) -a brand ambassador/alarming bell for potentially inappropriate medication in elderly inpatients

2021 ◽  
Vol 14 ◽  
Author(s):  
Rishabh Sharma ◽  
Parveen Bansal ◽  
Manik Chhabra ◽  
Malika Arora
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Inappropriate Medication ◽  
Tertiary Care ◽  
The Elderly ◽  
Potentially Inappropriate Medication ◽  
Beers Criteria ◽  
Care Hospital ◽  
Cross Sectional ◽  
Elderly Inpatients

Background: In the past decade, the prevalence of Potentially Inappropriate Medication (PIM) among elderly inpatients has increased drastically. However, limited data is available on PIM indicators, and PIMs use among the elderly in patients with Chronic Kidney Disease (CKD). Objective: To determine the prevalence of PIMs in elderly hospitalized patients with CKD. Methods: A cross-sectional study was carried out on 102 patients in a tertiary care hospital. PIMs were identified using Beers criteria 2019. A Chi-square test was used to determine the association between variables and PIMs use. Results: PIMs, as assessed according to AGS updated Beers criteria 2019 was found to be in more than 68.6% of patients of median age 65years and 3 number of diagnoses and seven days median length of stay. Most of the patients (47.1%) had ≥four diagnoses. The most common comorbidities in the patient were diabetes mellitus (n=54) and hypertension (n=55). Most of the subjects (66.7%) were on polypharmacy (5-9 medications/day), and 25.5% were on a higher level of polypharmacy (>10 medicines/day). Approximately 90% of the patients had very low CrCl < 21ml/min (calculated with the help of Cockcroft- Gault formula). A significant association between PIM use and an increased number of diagnoses, polypharmacy or high-level polypharmacy, was observed. Conclusion: The prevalence of PIMs in elderly inpatients suffering from CKD is relatively high. The study indicates negligence/ lack of awareness amongst physicians leading to increase PIM use. The authors propose that the CKD patients should attract the special attention of the physician and should be treated as brand ambassadors or alarming bells for PIM use.

scholarly journals The effect of hospitalization on potentially inappropriate medication use in older adults with chronic kidney disease

2019 ◽  
Vol 35 (6) ◽  
pp. 1119-1126 ◽  
Author(s):  
Wubshet H. Tesfaye ◽  
Barbara C. Wimmer ◽  
Gregory M. Peterson ◽  
Ronald L. Castelino ◽  
Matthew D. Jose ◽  
...  
Keyword(s):  
Older Adults ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Inappropriate Medication ◽  
Medication Use ◽  
Potentially Inappropriate Medication ◽  
Inappropriate Medication Use

Risk factors for high fall risk in elderly patients with chronic kidney disease

2021 ◽  
Author(s):  
Cihan Heybeli ◽  
Rumeyza Kazancioglu ◽  
Lee Smith ◽  
Nicola Veronese ◽  
Pinar Soysal
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Elderly Patients ◽  
Fall Risk

FEATURES OF CHRONIC KIDNEY DISEASE IN ELDERLY PATIENTS

2020 ◽  
pp. 113-120
Author(s):  
О. Н. Курочкина
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Elderly Patients ◽  
Clinical Situation ◽  
Chronic Glomerulonephritis ◽  
Hypertensive Nephropathy ◽  
Number Of Patients ◽  
Rate Of Decline ◽  
People Group ◽  
Group 1

Изучены особенности течения хронической болезни почек (ХБП) у пожилых пациентов на основании анализа регистра ХБП за 2015-2018 гг. В регистре 484 пациента, из них 231 (47,7%) мужчина, 253 (52,3%) женщины, средний возраст - 58,8±15,8 года. Пациенты были разделены на три группы: 1-я - 218 человек до 59 лет; 2-я - 207 человек 60-74 лет; 3-я - 59 человек 75 лет и старше. В 1-й группе ведущей причиной ХБП явился хронический гломерулонефрит -27,1%, во 2-й - хронический тубулоинтерстициальный нефрит (ТИН) - 21,7%, диабетическая нефропатия (ДН) - 20,8% и гипертоническая нефропатия - 15,9%; в 3-й - ТИН (27,1%), хронический пиелонефрит (ПН) - 15,9% и ДН (13,6%). С возрастом увеличивалась частота встречаемости ТИН ( р <0,1), ПН ( р <0,05), ишемической болезни почек ( р <0,05), подагрической нефропатии ( р <0,1). Среднее снижение СКФ - 3,99 мл/мин на 1,73 мза год наблюдения. Темп снижения СКФ в 1-й группе - 3,36±1,8 мл/мин на 1,73 мза год, во 2-й - 2,43±1,2 ( р <0,001 между 1-йи 2-й группой), в 3-й - 1,82±1,1 мл/мин на 1,73 мза год. Наблюдали отрицательную корреляцию с возрастом ( р <0,05). Формирование регистра больных с ХБП позволяет знать количество больных и причины ХБП у пациентов пожилого и старческого возраста, оценивать клиническую ситуацию, темпы снижения СКФ и выбирать лечебную тактику у этих пациентов. The purpose of the work is to study the characteristics of the course of chronic kidney disease in elderly patients based on the analysis of the register of chronic kidney disease (CKD) for 2015-2018. in the Department of Nephrology, the Komi Republican Clinical Hospital. There are 484 patients in the register, of whom 231 are men (47,7%), 253 women (52,3%). The average age is 58,8±15,8 years old. The patients were divided into 3 groups: persons under the age of 59 years old - 218 people (group 1); from 60 to 74 years old - 207 people (group 2); and over 75 years old - 59 people (group 3). Most patients are between the ages of 60 and 69 years old. In the 1 group, the chronic glomerulonephritis is the leading cause of CKD - 27,1%; in the 2 group - the chronic tubulo-interstitial nephritis (TIN) - 21,7%, the diabetic nephropathy (DN) - 20,8% and the hypertensive nephropathy - 15,9%; in the 3 group - TIN (27,1%), the chronic pyelonephritis (PN) (15,9%) and DN (13,6%). With increasing age, the incidence of TIN ( p <0,1), MO ( p <0,05), coronary kidney disease (IBP) ( p <0,05), gouty nephropathy ( p <0,1) were raised. The average reduction in GFR is 3,99 ml/min/1,73 m per year of observation. The rate of decline in GFR in the 1st group is 3,36±1,8 ml/min/1,73 m per year, in the 2 - 2,43±1,2 ( p <0,001 between group 1 and 2), in the 3 group - 1,82±1,1; with aging the negative correlation was observed ( p <0,05). 39 patients received hemodialysis, including: in the 1 group - 20 people (9%), in the 2 group - 18 (8,7%), in the 3 group - 1 patient (1,7%). Making the register of the patients with CKD allows us to know the number of patients and the causes of CKD among the patients of elderly and senile ages, to assess the clinical situation, the rate of decline in GFR and treatment tactics in these patients.

scholarly journals Treatment plans and outcomes in elderly patients reaching advanced chronic kidney disease

2018 ◽  
Vol 33 (12) ◽  
pp. 2182-2191 ◽  
Author(s):  
Olivier Moranne ◽  
Coraline Fafin ◽  
Sophie Roche ◽  
Maud Francois ◽  
Vincent Allot ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Elderly Patients ◽  
Advanced Chronic Kidney Disease ◽  
Treatment Plans

scholarly journals MEDICATION BURDEN AND INAPPROPRIATE PRESCRIPTION RISK AMONG ELDERLY WITH ADVANCED CHRONIC KIDNEY DISEASE

2019 ◽  
Author(s):  
Clarisse Roux-Marson ◽  
Jean-Baptiste Baranski ◽  
Coraline Fafin ◽  
Guillaume Extermann ◽  
Cecile Vigneau ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Elderly Patients ◽  
Healthcare Providers ◽  
Antihypertensive Agents ◽  
The Elderly ◽  
Anticholinergic Drugs ◽  
Cross Sectional ◽  
French Study ◽  
Sectional Analysis

Abstract Background Elderly patients with chronic kidney disease (CKD) frequently present comorbidities that put them at risk of polypharmacy and medication-related problems. This study aims to describe the overall medication profile of patients aged ≥ 75 years with advanced CKD from a multicenter French study and specifically the renally (RIMs) and potentially inappropriate-for-the-elderly medications (PIMs) that they take. Methods This is a cross-sectional analysis of medication profiles of individuals aged ≥ 75 years with eGFR < 20 ml/min/1.73m2 followed by a nephrologist, who collected their active prescriptions at the study inclusion visit. Medication profiles were analyzed according to route of administration, therapeutic classification, and their potential inappropriateness for these patients, according to Beers' criteria. Results We collected 5196 individual medication prescriptions for 556 patients, for a median of 9 daily medications [7-11]. Antihypertensive agents, antithrombotics, and antianemics were the classes most frequently prescribed. Moreover, 88% of patients had at least 1 medication classified as a RIM, and 21% of those were contraindicated drugs. At least 1 PIM was taken by 68.9%. The prescriptions most frequently requiring reassessment due to potential adverse effects were for proton pump inhibitors and allopurinol. The PIMs for which deprescription is especially important in this population are rilmenidine, long-term benzodiazepines, and anticholinergic drugs such as hydroxyzine. Conclusion We showed potential drug-related problems in elderly patients with advanced CKD. Healthcare providers must reassess each medication prescribed for this population, particularly the specific medications identified here.

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