Cross-sectional analysis of Toll-like receptor variants and bacterial vaginosis in African–American women with pelvic inflammatory disease: Table 1

We sought to understand pregnant women’s product preference and likelihood of use of topical microbicides for bacterial vaginosis (BV) prevention and treatment. Pregnant women (N = 196) in a obstetrics clinic completed a survey between June 2014 and January 2015 about vaginal product use for BV. This cross-sectional study explored product preferences, likelihood of product use for BV management and father of the baby (FOB) involvement. Most participants were under 30 (68%) and underrepresented minorities (47% Hispanic, 21% African-American). Most women preferred the gel (69%). Only 30% were likely to use either product for prevention of BV; 76% if high risk for BV; 83% treatment of BV. Anticipated FOB involvement in decision-making included that 46% would ask his opinion, 38% would inform him of the decision and 7% would need approval. Most (87%) would ask the FOB for reminders and 66% for insertion help. Those under 30 were more likely to agree to ask the FOB for reminders (p < 0.01) and insertion help (p = 0.05). African-American women were less likely to have their FOB help with insertion (p < 0.01). Product preferences may be less critical than risk perception. Involvement of the FOB in decision-making may be vital.

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Smoking policies in the home have less influence on cigarettes per day and nicotine dependence level among African American than White smokers: A cross-sectional analysis

Journal of the National Medical Association ◽

10.1016/j.jnma.2019.07.002 ◽

2019 ◽

Vol 111 (6) ◽

pp. 606-615 ◽

Cited By ~ 1

Author(s):

Lesia M. Ruglass ◽

James C. Root ◽

Naomi Dambreville ◽

Alina Shevorykin ◽

Noshin Haque ◽

...

Keyword(s):

African American ◽

Nicotine Dependence ◽

Cross Sectional ◽

Cross Sectional Analysis ◽

Smoking Policies ◽

Dependence Level ◽

Sectional Analysis

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Genetic and Environmental Risks for High Blood Pressure Among African American Mothers and Daughters

Biological Research For Nursing ◽

10.1177/1099800409334817 ◽

2009 ◽

Vol 11 (1) ◽

pp. 53-65 ◽

Cited By ~ 23

Author(s):

Jacquelyn Y. Taylor ◽

Rosanna Maddox ◽

Chun Yi Wu

Keyword(s):

Physical Activity ◽

Blood Pressure ◽

African American ◽

African American Women ◽

Sodium Intake ◽

Buccal Swab ◽

African American Mothers ◽

Cross Sectional ◽

Mothers And Daughters ◽

American Women

Objective: To determine the relationship between genetic and environmental lifestyle factors (physical activity and sodium) on blood pressure (BP) among African-American women. Method: In this cross-sectional study involving 108 African-American mothers and daughters from a Midwestern area, investigators obtained BP measurements, information on minutes of physical activity, amount of sodium intake, and buccal swab saliva samples. Results: Of the 4 single nucleotide polymorphisms (SNPs) on the sodium bicarbonate cotransporter gene (SLC4A5), rs8179526 had a statistically significant interaction with cytosine/thymine (C/T) genotype by sodium status on systolic BP (SBP; p = .0077). For gene × physical activity interaction, 2 significant interactions (cytosine/adenine [C/A] genotype by physical activity and adenine/adenine [A/A] genotype by physical activity, p = .0107 and p = .0171, respectively) on SBP and 1 on diastolic BP (DBP; A/A genotype by physical activity, p = .0233) were found on rs1017783. Two significant guanine/adenine [G/A] genotype by physical activity interactions were found on rs6731545 for SBP and DBP (p = .0160 and p = .0492, respectively). Discussion: A gene × environmental interaction with rs8179526 has a protective effect on SBP in African-American women with high sodium intake. Participants with C/T genotype of rs8179526 who consumed greater than 2,300 mg of sodium had lower SBP than those who consumed less than recommended. Women with thymine/thymine (T/T) genotype of rs8179526 who consumed greater than 2,300 mg had lower SBP than those who consumed less. Awareness of both the protective and deleterious properties of rs8179526 in African-American women may one day assist in determining appropriate treatment plans.

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How does social integration influence breast cancer control among urban African-American women? Results from a cross-sectional survey

BMC Women s Health ◽

10.1186/1472-6874-8-4 ◽

2008 ◽

Vol 8 (1) ◽

Cited By ~ 10

Author(s):

Ann Carroll Klassen ◽

Carmen Washington

Keyword(s):

Breast Cancer ◽

African American ◽

Social Integration ◽

African American Women ◽

Cancer Control ◽

Cross Sectional Survey ◽

Cross Sectional ◽

American Women ◽

Breast Cancer Control

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A Systematic Review of DNA Methylation and Preterm Birth in African American Women

Biological Research For Nursing ◽

10.1177/1099800416669049 ◽

2016 ◽

Vol 19 (3) ◽

pp. 308-317 ◽

Cited By ~ 12

Author(s):

Veronica Barcelona de Mendoza ◽

Michelle L. Wright ◽

Comfort Agaba ◽

Laura Prescott ◽

Alexandra Desir ◽

...

Keyword(s):

Dna Methylation ◽

African American ◽

Preterm Birth ◽

African American Women ◽

Small Sample Size ◽

Small Sample ◽

Future Research ◽

Cross Sectional ◽

American Women ◽

Study Designs

Background: The causes of many cases of preterm birth (PTB) remain enigmatic. Increased understanding of how epigenetic factors are associated with health outcomes has resulted in studies examining DNA methylation (DNAm) as a contributing factor to PTB. However, few studies on PTB and DNAm have included African American women, the group with the highest rate of PTB. Methods: The objective of this review was to systematically analyze the existing studies on DNAm and PTB among African American women. Results: Studies ( N = 10) were limited by small sample size, cross-sectional study designs, inconsistent methodologies for epigenomic analysis, and evaluation of different tissue types across studies. African Americans comprised less than half of the sample in 50% of the studies reviewed. Despite these limitations, there is evidence for an association between DNAm patterns and PTB. Conclusions: Future research on DNAm patterns and PTB should use longitudinal study designs, repeated DNAm testing, and a clinically relevant definition of PTB and should include large samples of high-risk African American women to better understand the mechanisms for PTB in this population.

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