Duodenal sigmoid flexure volvulus and gall bladder displacements in dairy cows

Individual and combined effects of several isomers of retinoic acid (RA) and 1,25-dihydroxyvitamin D3 (1,25-(OH)2D3) on interferon-gamma (IFN-gamma) secretion by blood mononuclear leukocytes (MNL) from nulliparous and postparturient Holstein cattle were evaluated in vitro. In the first experiment, effects on incubation period (24 to 72 hours) and time of supplementation (0 to 32 hours) with all-trans, 9-cis, 13-cis-, and 9,13-dicis-RAs (0 to 100 nM) on IFN-gamma secretion by pokeweed mitogen (PWM)-stimulated (0 and 10 mug/ml) MNL from nulliparous cattle were evaluated. In the second experiment, MNL from postparturient cows (bled at 0, 2, 4, and 16 days postpartum) were stimulated with PWM (0 and 10 mug/ml) in the presence of RA isomers (9-cis- or 9,13-dicis-RA; 0 to 100 nM), 1,25-(OH)2D3 (0 to 100 nM), or with combinations of these metabolites. The results show that individual isomers of RA had no effect on IFN-gamma secretion by PWM-stimulated MNL from nulliparous or postparturient cows. Furthermore 1,25-dihydroxyvitamin D3 inhibited IFN-gamma secretion by MNL from nulliparous and postparturient dairy cows; however, the degree of inhibition was greater when 9-cis- and 9,13-dicis-RA were also present in the cultures. Finally mononuclear leukocytes from postparturient dairy cows produced substantially less IFN-gamma than did MNL from nulliparous cattle. It is concluded that retinoic acids individually did not affect the capacity of leukocytes from dairy cattle to secrete IFN-gamma. This result is in marked contrast to studies in monogastric species indicating that RAs inhibit IFN-gamma secretion by peripheral blood T cells. Inhibition of IFN-gamma secretion by 1,25-(OH)2D3 was potentiated by 9-cis- and 9,13-di-cis-retinoics acids, suggesting that an excess of dietary vitamins A and D may compromise further the naturally immunosuppressed postparturient dairy cow. Additional research is necessary to determine if the combined effects of these metabolites on IFN-gamma secretion represent an increased susceptibility of the dairy cow to infectious diseases during the periparturient period. Lower secretion of IFN-gamma by MNL from postpartutient dairy cows, relative to nulliparous cattle, suggests that recently-calved cows are naturally immunosuppressed.

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Chronic Cholezystitis Misleading as Tumor of the Gall Bladder with Concomitant Liver Abscess

Swiss Surgery ◽

10.1024/1023-9332.7.1.28 ◽

2001 ◽

Vol 7 (1) ◽

pp. 28-31 ◽

Cited By ~ 2

Author(s):

Teebken ◽

Bartels ◽

Fangmann ◽

Nagel ◽

Klempnauer

Keyword(s):

Gall Bladder ◽

Liver Abscess ◽

Solide Tumoren ◽

Fand Sich ◽

Histologische Untersuchung ◽

Chronische Entzündungen

Ein 58jähriger Mann wurde mit Übelkeit, Oberbauchschmerzen, einem palpablen Tumor im rechten oberen Epigastrium und begleitendem Fieber aber fehlender Leukozytose und CRP-Erhöhung aufgenommen. Sowohl die Ultraschalluntersuchung als auch eine im Anschluss durchgeführte Computertomographie deuteten auf einen malignen Tumor der Gallenblase mit Infiltration der Leber und begleitender Abszessformation in den Segmenten 4b und 3 hin. Die Indikation zur Entfernung des Tumors im Sinne einer Hemihepatektomie links mit Cholezystektomie und Abszessdrainage wurde gestellt. Intraoperativ fand sich dann jedoch eine chronisch-eitrige Cholezystitis ohne Beteiligung der Leber selbst, sodass nur eine Cholezystektomie durchgeführt werden musste. Die histologische Untersuchung der Gallenblase erbrachte keinen Hinweis auf ein malignes Geschehen. Der Patient erholte sich gut von dem operativen Eingriff und konnte sieben Tage später entlassen werden. Diese Fallbeschreibung zeigt die Probleme auf, die bei der Differentialdiagnostik von entzündlichen und malignen Gallenblasenerkrankungen mit Beteiligung von angrenzenden Strukturen, insbesondere der Leber, bestehen. Trotz apparativer Untersuchungen wie Sonographie und Computertomogramm ist die letztendlich richtige Diagnose häufig nur intraoperativ zu stellen und erst dann die adäquate Therapie festlegbar. Chronische Entzündungen der Gallenblase können als solide Tumoren imponieren und dann als maligne Prozesse der Gallenblase und der angrenzenden Lebersegmente fehlinterpretiert werden.

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Influence of the herbal component of a commercial feed additive on serum parameters, fertility and longevity of dairy cows

Planta Medica ◽

10.1055/s-0030-1264919 ◽

2010 ◽

Vol 76 (12) ◽

Author(s):

M Walkenhorst ◽

S Ivemeyer ◽

J Spranger ◽

G Arndt ◽

R Schaette

Keyword(s):

Dairy Cows ◽

Feed Additive ◽

Serum Parameters ◽

Commercial Feed

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Tc-99m Labeled Complexes of Aldehydes and Glutamate as Cholescintigraphic Agents

Nuklearmedizin ◽

10.1055/s-0038-1624914 ◽

1975 ◽

Vol 14 (04) ◽

pp. 330-338

Author(s):

L. G. Colombetti ◽

J. S. Arnold ◽

W. E. Barnes

Keyword(s):

Nuclear Medicine ◽

Gall Bladder ◽

Rose Bengal ◽

Valence State ◽

Monosodium Glutamate ◽

Kinetic Studies ◽

Scintillation Camera ◽

Blood Clearance ◽

Lower Valence ◽

Wire Basket

SummaryTc-99m pyridoxylidene glutamate has proven to be an excellent biliary scanning agent, far superior in many respect to the commonly used 1-131 rose bengal. The preparation of the compound as previously reported by Baker et al is too time consuming and requires the use of an autoclave which is not available in most nuclear medicine departments. In our facility, we have been preparing similar compounds using several aldehydes and monosodium glutamate to make labeled complexes having the same pharmacological characteristics. The mixture of monosodium glutamate, aldehyde, and Tc-99m pertechnetate is made slightly alkaline, purged with helium, and placed in a sealed vial. The vial, which is protected by a wire basket, is then heated in a laboratory oven at 130° C for a period of 15 to 20 minutes. During this time, the technetium is reduced to a lower valence state and bound to the complex formed. Chromatographic data show that these compounds are chemically similar to that previously reported. The compounds prepared concentrate in the gall bladder of the rabbit in less than 10 minutes. Kinetic studies have been performed on dogs with a scintillation camera and small digital computer to measure rates of blood clearance, liver and gall bladder uptake, and excretion into the intestine. The aldehyde — glutamate complex promises to be a useful scanning agent for the diagnosis of biliary and hepatocellular diseases.

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Relation between intravascular electrolyte level and course of parturition in dairy cows

Tierärztliche Praxis Ausgabe G Großtiere / Nutztiere ◽

10.1055/s-0038-1623185 ◽

2013 ◽

Vol 41 (05) ◽

pp. 289-296 ◽

Cited By ~ 2

Author(s):

K. Seyrek-Intas ◽

K. Failing ◽

G. Yilmazbas Mecitoglu ◽

H. Bostedt ◽

D. Seyrek-Intas

Keyword(s):

Dairy Cows ◽

Inorganic Phosphate ◽

Post Partum ◽

Total Calcium ◽

Normal Delivery ◽

P Values ◽

Normal Birth ◽

Factors Influencing ◽

Electrolyte Homeostasis ◽

Convalescence Phase

Summary Objective: To determine the intravascular electrolyte status in dairy cows with respect to age and different courses of parturition to clarify etiological factors influencing peri- or intrapartal imbalances of electrolyte homeostasis. Material and methods: A total of 64 cows at birth were evaluated (primiparous n = 34, pluriparous n = 30). Thirty-three cows showed normal delivery, while 31 cows had a complicated birth. Blood samples were collected intra partum (i. p.) and 2, 4, 6, 8, 12, 16, 24 h post partum (p. p.) as well as [2, 3, 4, 5, 7, 10 days p. p. and levels of total calcium (Catotal), ionized calcium (Caion), inorganic phosphate (Pa), Mg, Na, K, Cl were determined. Results: The results revealed that electrolytes show great fluctuation during and immediately p. p. in relation to age. Already during parturition pluriparous cows had a lower Catotal and Pa concentration compared to primiparous animals. Cows with dystocia exhibited a more intensive and longer lasting decrease of Ca compared to cows with normal birth. In relation to age and severity of birth Pa concentration showed a differing but basically typical course for this electrolyte. Mg, Na, K and Cl concentrations were higher during and immediately after birth compared to p. p. values. Until day 10 p. p. these electrolyte concentrations declined more in older cows with dystocia compared to younger animals. However, the influence of dystocia on concentration of these electrolytes was milder in contrast to Ca and Pa. Conclusions: In summary, primarily older cows are predisposed to imbalances of electrolyte homeostasis intra partum and at the beginning of the lactation. These changes are potentiated in case of complications during parturition. Intravascular Catotal, Caion as well as Pa are most severely affected. Clinical relevance: These results may constitute the basis for a comprehensive metaphylaxis during the peripartal period, especially in cows after dystocia, to positively influence the early convalescence phase.

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A case study on year round fodder production scheme for smallholder dairy producers in Bangladesh

Bangladesh Journal of Livestock Research ◽

10.3329/bjlr.v26i1-2.49940 ◽

2020 ◽

Vol 26 (1-2) ◽

pp. 79-102

Author(s):

NR Sarker ◽

F Tabassum D Yeasmin ◽

MA Habib ◽

MR Amin

Keyword(s):

Dairy Cows ◽

Family Income ◽

Live Weight ◽

Production Model ◽

Variable Cost ◽

Small Scale ◽

Common Salt ◽

Cost Ratio ◽

Her Family ◽

Fodder Production

This study was undertaken to develop a year round fodder production model for small scale dairy farmers. Five pregnant dairy cows of Red Chittagong Cattle (RCC) genotype were selected. For rearing five cows, 66 decimal of land was selected from existing fodder plots under Pachutia Research Farm at Bangladesh Livestock Research Institute (BLRI), Savar, Dhaka. The selected land was divided into two parts (33 decimal in each). One part was brought under perennial (Napier-4 and Splendida) and the 2nd part of land for seasonal (Maize & Matikalai) fodder production. Data on live weight and live weight gain of cows, birth weight of calves, feed intake, milk production, actual biomass yield for both perennial and seasonal fodder, yearly manure production were recorded and calculated. Napier-4 grass, splendida, maize, straw, silage were supplied to the experimental cows according to the seasonal availability in different months. Concentrate mixture were also supplied consisting of wheat bran, kheshari (red gram), soybean meal, maize crushed, til oil cake, DCP and common salt. Economics of the model revealed that considering the sale of milk, calves and manure and cost included only feed and land leased, a farm/family rearing 5 indigenous dairy cows with his/her family labours, he/she could earn around BDT 98 thousand in a year (1$ = 85 BDT) and the benefit cost ratio of the model on total variable cost and total cost were 1.86 and 1.66, respectively. Therefore, it may be recommended that a farmer having 5 adult dairy cows with 66 decimal land under fodder cultivation may earn substantial share of his/her family income as small-scale rural dairying. Bang. J. Livs. Res. Vol. 26 (1&2), 2019: P. 89-102

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