Nutritional Factors in the Biochemical Pathology of Corynebacterial Kidney Disease in the Coho Salmon (Oncorhynchus kisutch)

1973 ◽  
Vol 30 (2) ◽  
pp. 296-298 ◽  
Author(s):  
Gary A. Wedemeyer ◽  
A. J. Ross
Keyword(s):  
Kidney Disease ◽  
Coho Salmon ◽  
Disease Incidence ◽  
Oncorhynchus Kisutch ◽  
Blood Chemistry ◽  
Infected Fish ◽  
Acid Base Balance ◽  
Corn Gluten ◽  
Base Balance ◽  
Biochemical Pathology

The influence of diet ingredient on the morbidity and biochemical pathogenesis of corynebacterial kidney disease was investigated using juvenile coho salmon (Oncorhynchus kisutch) fed the Abernathy dry ration made up with either corn gluten or cottonseed meal (isoprotein, isocaloric substitution). Evaluation of incidence of infection, pituitary activation and aspects of carbohydrate metabolism, acid-base balance, renal function, and hematopoietic activity showed that the actual disease incidence was about the same for both diets but the nonspecific stress of infection was more severe in fish fed the corn gluten.Discriminant function calculations combining four physiological parameters gave a probability of 0.86 for successfully diagnosing infected fish on the basis of these blood chemistry tests.

Some Blood Chemistry Values for the Juvenile Coho Salmon (Oncorhynchus kisutch)

1971 ◽  
Vol 28 (4) ◽  
pp. 606-608 ◽  
Author(s):  
Gary Wedemeyer ◽  
K. Chatterton
Keyword(s):  
Coho Salmon ◽  
Oncorhynchus Kisutch ◽  
Blood Chemistry ◽  
Clinical Test ◽  
Acid Base Balance ◽  
Acid Base ◽  
Arterial Blood ◽  
Blood Ph ◽  
Normal Ranges ◽  
Base Balance

Overlapping Gaussian distribution curves were resolved into normal ranges for 1800 clinical test values obtained from caudal arterial blood or plasma of more than 1000 juvenile coho salmon (Oncorhynchus kisutch) held under defined conditions of diet and temperature. Estimated normal blood chemistry ranges were bicarbonate, 9.5–12.6 mEq/liter; blood urea nitrogen (BUN), 0.9–3.4 mg/100 ml; chloride, 122–136 mEq/liter; cholesterol, 88–262 mg/100 ml;pCO2, 2.6–6.1 mm Hg (10 C); glucose, 41–135 mg/100 ml; hematocrit, 32.5–52.5%; hemoglobin, 6.5–9.9 g/100 ml; total protein, 1.4–4.3 g/100 ml; blood pH (10 C), 7.51–7.83. The calculated range of normal acid–base balance vs. water temperature is also presented.

Some changes in the blood cells of diseased coho salmon

1979 ◽  
Vol 57 (7) ◽  
pp. 1458-1464 ◽  
Author(s):  
R. J. G. Lester ◽  
Joan Budd
Keyword(s):  
Kidney Disease ◽  
Electron Micrographs ◽  
Blood Cells ◽  
Coho Salmon ◽  
Bacterial Pathogen ◽  
Oncorhynchus Kisutch ◽  
Infected Fish ◽  
Blood Samples ◽  
Thrombocyte Count ◽  
Bacterial Kidney Disease

Blood samples were taken from fingerling coho salmon (Oncorhynchus kisutch) that had been experimentally infected with either the bacterial pathogen causing vibriosis or that causing bacterial kidney disease. In the 2nd week after inoculation, smears from the Vibrio-infected fish contained enlarged thrombocytes, pinched erythrocytes, and neutrophils with vesicles. The total number of thrombocytes was reduced to 8000 per microlitre, though this returned to 20 000 per microlitre in the 3rd week in those fish that survived.Blood smears from fish given the kidney disease bacterium contained enlarged thrombocytes and what appeared to be collapsed reticulocytes, in the 2nd and 3rd weeks. The thrombocyte count averaged 6500 per microlitre, and there were reduced numbers of other cells. Bacteria were found in thrombocytes, neutrophils, and monocytes.Light micrographs of 26 normal or modified cells and electron micrographs of two granulocytes are included.

The Stress of Formalin Treatments in Rainbow Trout (Salmo gairdneri) and Coho Salmon (Oncorhynchus kisutch)

1971 ◽  
Vol 28 (12) ◽  
pp. 1899-1904 ◽  
Author(s):  
Gary Wedemeyer
Keyword(s):  
Rainbow Trout ◽  
Coho Salmon ◽  
Oncorhynchus Kisutch ◽  
Salmo Gairdneri ◽  
Acid Base Balance ◽  
Acid Base ◽  
Blood Ph ◽  
Base Balance ◽  
Ventilation Rates ◽  
Gill Function

Changes in gill function, acid–base balance and pituitary activation occurring during standard 200 ppm formalin treatments of juvenile rainbow trout (Salmo gairdneri) and coho salmon (Oncorhynchus kisutch) were compared. Plasma Cl−, Ca++, total CO2, and interrenal vitamin C in the trout declined continuously and in proportion to the exposure time, but the salmon were able to maintain these metabolic parameters at approximately initial levels. Blood pH and alkaline reserve regulation of the salmon was also less affected by formalin treatments, especially during prolonged exposures. The oxygen consumption of both species was depressed, but substantially more so in the trout than could be accounted for by decreased ventilation rates. Little frank hemolysis occurred in either species, but there was a significant bilirubinemia in the trout.

Relative Resistances of Three Transferrin Genotypes of Coho Salmon (Oncorhynchus kisutch) and Their Hematological Responses to Bacterial Kidney Disease

1977 ◽  
Vol 34 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Bruce K. Suzumoto ◽  
Carl B. Schreck ◽  
John D. McIntyre
Keyword(s):  
Kidney Disease ◽  
Coho Salmon ◽  
Oncorhynchus Kisutch ◽  
Head Kidney ◽  
Infected Fish ◽  
Control Fish ◽  
Saline Control ◽  
Bacterial Kidney Disease ◽  
Total Plasma Protein ◽  
And Control

Juvenile coho salmon (Oncorhynchus kisutch) of three transferrin genotypes (AA, AC, and CC) were experimentally infected with the causative agent of bacterial kidney disease (BKD) and mortalities observed. Six experimental and control groups were used: 1) bacteria-infected + no Fe+3; 2) bacteria-infected + low Fe+3 levels; 3) bacteria-infected + high Fe+3 levels; 4) saline control; 5) high Fe+3 control; and 6) low Fe+3 control. In all experimental groups, the AA genotype was the most susceptible to BKD and the CC genotype the most resistant. Addition of exogenous iron did not appear to increase the pathogenicity of the disease. Distribution and uptake of radioiron (59Fe) in control and BKD-infected fish was studied. BKD-infected fish were found to have consistently higher levels of 59Fe in whole blood, plasma, and liver than control fish. In control and experimental fish, spleen, head kidney, and liver tissues were found to accumulate 59Fe, while white muscle and gall bladder tissues did not. The effect of BKD on certain hematological characteristics also was determined. Hemoglobin, packed cell volume, total plasma protein, plasma iron, and plasma corticoid levels all may have decreased with the progression of BKD.

scholarly journals Histopathology of BKD(Bacterial kidney disease) occurred in sea-cultured coho salmon (Oncorhynchus kisutch).

1989 ◽  
Vol 24 (1) ◽  
pp. 17-21 ◽  
Author(s):  
Yutaka HAYAKAWA ◽  
Takahiko HARADA ◽  
Kishio HATAI ◽  
Saburoh S. KUBOTA ◽  
Toshio BUNYA ◽  
...  
Keyword(s):  
Kidney Disease ◽  
Coho Salmon ◽  
Oncorhynchus Kisutch ◽  
Bacterial Kidney Disease

Changes in Blood Chemistry and Blood Cell Morphology in Coho Salmon (Oncorhynchus kisutch) Following Exposure to Sublethal Levels of Total Residual Chlorine in Municipal Wastewater

1976 ◽  
Vol 33 (4) ◽  
pp. 776-782 ◽  
Author(s):  
James A. Buckley ◽  
Cecil M. Whitmore ◽  
Robert I. Matsuda
Keyword(s):  
Municipal Wastewater ◽  
Coho Salmon ◽  
Sewage Treatment ◽  
Sewage Treatment Plant ◽  
Treatment Plant ◽  
Oncorhynchus Kisutch ◽  
Blood Chemistry ◽  
Municipal Sewage ◽  
Residual Chlorine ◽  
Hematological Effects

Yearling coho salmon (Oncorhynchus kisutch) were exposed for 12 wk to either 0.3, 1.1, or 3.6% chlorinated municipal sewage treatment plant effluent with seawater diluent (average salinity 28‰)under continuous flow conditions. The maximum safe concentration of effluent lies between 0.3 and 1.1% (average total residual chlorine (TRCl2) content 0.003 and 0.009 mg/liter, respectively). Effluent concentrations of 0.3% produced no discernible effects on the fish. Concentrations of 1.1 and 3.6% (average content of TRCl2 0.030 mg/liter) resulted in reductions of hemoglobin and hematocrit to levels indicative of anemia. Observations of the erythrocytes revealed lysed and degenerating cells, increased numbers of circulating immature cells, and abnormal cells. These hematological effects are attributed to the oxidative nature of TRCl2.

scholarly journals ACID-BASE BALANCE IN HYPERTENSIVE PATIENTS WITH CHRONIC KIDNEY DISEASE: INFLUENCE OF DIABETES

2021 ◽  
Vol 39 (Supplement 1) ◽  
pp. e298
Author(s):  
Giuseppe Mule’ ◽  
Caterina Carollo ◽  
Alessandra Sorce ◽  
Marta Giambrone ◽  
Alida Ferrara ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Acid Base Balance ◽  
Acid Base ◽  
Hypertensive Patients ◽  
Base Balance

scholarly journals Carp Edema Virus Infection Is Associated With Severe Metabolic Disturbance in Fish

2021 ◽  
Vol 8 ◽  
Author(s):  
Jiri Pikula ◽  
Lubomir Pojezdal ◽  
Ivana Papezikova ◽  
Hana Minarova ◽  
Ivana Mikulikova ◽  
...  
Keyword(s):  
Carbon Dioxide ◽  
Principal Component ◽  
Disease Status ◽  
Blood Chemistry ◽  
Infected Fish ◽  
Metabolic Disturbance ◽  
Acid Base Balance ◽  
Virus Identification ◽  
Dissolved Carbon ◽  
Dissolved Carbon Dioxide

Significant mortalities associated with emerging viral diseases are challenging the economy of common carp aquaculture. As such, there is an increased need to disentangle how infected fish cope with progressive disease pathology and lose the ability for homeostatic maintenance of key physiological parameters. A natural carp edema virus (CEV) infection outbreak at a carp fish farm provided an opportunity to examine diseased and healthy carp in the same storage pond, thereby contributing to our better understanding of CEV disease pathophysiology. The disease status of fish was determined using PCR-based virus identification combined with analysis of gill pathology. Compared with healthy control carp, the blood chemistry profile of CEV-infected fish revealed major disruptions in electrolyte and acid-base balance (i.e., hyponatraemia, hypochloraemia, hyperphosphatemia, elevated pH, base excess, and anion gap and decreased partial dissolved carbon dioxide). In addition, we recorded hyperproteinaemia, hyperalbuminaemia, hypotonic dehydration, endogenous hyperammonaemia, and decreased lactate along with increased creatinine, alkaline phosphatase, alanine aminotransferase, and aspartate aminotransferase. Red blood cell associated hematology variables were also elevated. The multivariate pattern of responses for blood chemistry variables (driven by sodium, pH, partial dissolved carbon dioxide, ammonia, and albumin in the principal component analysis) clearly discriminated between CEV-infected and control carp. To conclude, we show that CEV infection in carp exerts complex adverse effects and results in severe metabolic disturbance due to the impaired gill respiratory and excretory functioning.

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