Cadmium Inhibition of Erythropoiesis in Goldfish, Carassius auratus
1984 ◽
Vol 41
(12)
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pp. 1829-1834
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Keyword(s):
Red Cell
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Goldfish (Carassius auratus) maintained on a highly nutritional diet under normoxic circumstances at 25 °C in soft water had mean half-recovery times of 22.5 h (hemoglobin) and 21.0 h (hematocrit) following anemia induced with phenylhydrazine HCl. Corresponding values for fish exposed under similar conditions to 1, 5, 15, and 25% of the softwater 240-h cadmium LC50 were 41.9, 53.1, 164.8, and 344.3 h (hemoglobin) and 44.7, 46.5, 348.9, and 263.2 h (hematocrit), respectively. We suggest that whereas cadmium has relatively little effect upon circulating erythrocytes, it seriously impedes red cell formation and hemoglobin synthesis at concentrations well below the acutely lethal level.
1976 ◽
Vol 33
(6)
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pp. 1403-1407
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1966 ◽
Vol 23
(8)
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pp. 1109-1120
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1978 ◽
Vol 35
(1)
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pp. 35-42
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1981 ◽
Vol 70
(3)
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pp. 431-434
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1981 ◽
Vol 38
(10)
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pp. 1182-1188
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