Report on the Na+/H+ Exchanger Satellite Meeting at the 53rd Annual Meeting of the Canadian Society of Biochemistry, Molecular and Cellular Biology

2011 ◽  
Vol 89 (2) ◽  
pp. 85-86 ◽  
Author(s):  
R. T. Alexander ◽  
L. Fliegel

The Satellite Meeting on Na+/H+ Exchangers, held on 17 April 2010, covered a range of new developments in this field. The symposium was chaired by Dr. Larry Fliegel, University of Alberta, and the speakers were Dr. John Orlowski of McGill University, Dr. Jan Rainey of Dalhousie University, Dr. Etana Padan of The Hebrew University of Jerusalem, Dr. Masa Numata of The University of British Columbia, Dr. Pavel Dibrov from the University of Manitoba, Dr. Todd Alexander of the University of Alberta, and Grant Kemp of the University of Alberta. Talks ranged from organellar pH homeostasis to structure and function of Na+/H+ exchanger proteins. Highlights of the symposium included elucidation of the structure of transmembrane regions of the NHE1 isoform and development of a new model of the NHE1 protein based on the E. coli Na+/H+ exchanger. The symposium brought together scientists from different corners of the world. The discussions that followed were lively and many scientists received constructive comments from their peers.

Author(s):  
Mohammad Mehdi Ebadi ◽  
Michele Richards ◽  
Carol Brown ◽  
Samer Adeeb

Growing attention to environmental sustainability, modular construction, and application of new generation of materials, accompanied with advanced data collection techniques and computer modeling, has revolutionized the area of Civil Engineering within the past few years. This demonstrates the necessity of continually reviewing the curriculum to assure that graduating engineers are knowledgeable enough to deal with complex problems in their area of specialty. This is also essential to satisfy the continual improvement process (CIP) requirements mandated by the Canadian Engineering Accreditation Board (CEAB). As a first step to design a rigorous CIP, a comprehensive comparison was made between the Civil Engineering curricula of the University of Alberta (UofA) and eight other major universities across Canada, including the University of Calgary, University of Toronto, McGill University, University of Windsor, University of Regina, University of British Columbia (UBC), University of Waterloo, and Polytechnic of Montreal. After categorizing the courses into twelve different streams, it was observed that some universities paid less attention to a specific stream in comparison with the average, which could be identified as a gap in the curriculum. A capstone design or group design project that is multidisciplinary and covers multiple areas of specialty is the predominant approach followed by most of the universities.


Author(s):  
Tracy Stewart ◽  
Denise Koufogiannakis ◽  
Robert S.A. Hayward ◽  
Ellen Crumley ◽  
Michael E. Moffatt

This paper will report on the establishment of the Centres for Health Evidence (CHE) Demonstration Project in both Edmonton at the University of Alberta and in Winnipeg at the University of Manitoba. The CHE Project brings together a variety of partners to support evidence-based practice using Internet-based desktops on hospital wards. There is a discussion of the CHE's cultural and political experiences. An overview of the research opportunities emanating from the CHE Project is presented as well as some early observations about information usage.


1973 ◽  
Vol 19 ◽  
pp. 234-267 ◽  

James Bertram Collip was a pioneer in endocrine research, especially in its biochemical aspects. Following an excellent training in biochemistry under Professor A. B. Macallum, F.R.S., at the University of Toronto, he spent thirteen years at the University of Alberta in Edmonton. There was a momentous year at the University of Toronto about midway through the Edmonton period; this coincided with the discovery of insulin by Sir Frederick G. Banting, F.R.S., and Professor Charles S. Best, F.R.S., and the experience altered the course of his career. Henceforth, Professor Collip’s life was dominated by an urge to discover hormones that would be useful in clinical medicine. Success attended these efforts, first in the isolation of the parthyroid hormone, called parathormone, while he was at the University of Alberta and later in the identification of placental and pituitary hormones during particularly fruitful years at McGill University. There were other important facets to Professor Collip’s career. These included the training of young scientists, many of whom subsequently came to occupy positions of responsibility, work with the National Research Council of Canada, and in his latter years an important contribution as Dean of the Faculty of Medicine, University of Western Ontario. In addition to a life of fulfilment through accomplishments of scientific and medical importance, Professor Collip’s career was enriched by a happy family life and by the friendship of a host of individuals who were attracted to his brilliance as a scientist and his warm personality.


2015 ◽  
Vol 45 (4) ◽  
pp. 298-321
Author(s):  
J Paul Grayson

Teaching evaluations have become part of life on Canadian campuses; however, there is no agreement among researchers as to their validity. In this article, comparisons were made between first- and third-year collective evaluations of professors’ performance at the University of British Columbia, York University, and McGill University. Overall, it was found that students who provided low evaluations in their first year were also likely to do so in their third year. This effect held independent of degree of campus engagement, sex, student status (domestic or international), and generational status (students who were the first in their families to attend university, compared to those who were not). Given that over the course of their studies, students likely would have been exposed to a range of different behaviours on the part of their professors, it is argued that the propensity of a large number of students to give consistently low evaluations was a form of “habitual behaviour.”  


Author(s):  
Melissa Dalgleish

Phyllis Webb, OC is a Canadian poet, teacher, and broadcaster. She was born in Victoria, British Columbia and attended the University of British Columbia and McGill University. She is the author of numerous books of poetry, a selection of prose, and a collection of broadcast scripts, essays and reviews published as Talking (1982). Her first collection of poems was published alongside work by Eli Mandel and Gael Turnbull in Trio (1954). Webb’s first full-length collection, Even Your Right Eye (1956) was followed by The Sea is Also a Garden (1962). She began working at CBC Toronto in 1964 and acted as the producer of the ‘Ideas’ programme from 1967–1969. Her 1965 collection Naked Poems marked a point of departure with its compact forms and erotic evocation of lesbian desire. After returning to the West Coast, Webb did not publish another full-length collection until Wilson’s Bowl (1980). She won the Governor General’s Award for The Vision Tree (1982). Webb’s interest in the Persian ghazal form inspired Sunday Water: Thirteen Anti-Ghazals (1982) and Water and Light: Ghazals and Anti-Ghazals (1984). Her consistent concern with form manifests itself in her formal experimentation and her meticulous crafting of poems.


Author(s):  
Tristan H. Lambert

Glenn M. Samm is at the University of British Columbia reported (Angew. Chem. Int. Ed. 2012, 51, 10804) the photofluorodecarboxylation of aryloxyacids such as 1 using Selectfluor 2. Jean-François Paquin at the Université Laval found (Org. Lett. 2012, 14, 5428) that the halogenation of alcohols (e.g., 4 to 5) could be achieved with [Et2NSF2]BF4 (XtalFluor-E) in the presence of the appropriate tetraethylammonium halide. A method for the reductive bromination of carboxylic acid 6 to bromide 7 was developed (Org. Lett. 2012, 14, 4842) by Norio Sakai at the Tokyo University of Science. Professor Sakai also reported (Org. Lett. 2012, 14, 4366) a related method for the reductive coupling of acid 8 with octanethiol to produce thioether 9. The esterification of primary alcohols in water-containing solvent was achieved (Org. Lett. 2012, 14, 4910) by Michio Kurosu at the University of Tennessee Health Science Center using the reagent 11, such as in the conversion of alcohol 10 to produce 12 in high yield. Hosahudya N. Gopi discovered (Chem. Commun. 2012, 48, 7085) that the conversion of thioacid 13 to amide 14 was rapidly promoted by CuSO4. A ruthenium-catalyzed dehydrative amidation procedure using azides and alcohols, such as the reaction of 15 with phenylethanol to produce 16, was reported (Org. Lett. 2012, 14, 6028) by Soon Hyeok Hong at Seoul National University. An alternative oxidative amidation was developed (Tetrahedron Lett. 2012, 53, 6479) by Chengjian Zhu at Nanjing University and the Shanghai Institute of Organic Chemistry who utilized catalytic tetrabutylammonium iodide and disubstituted formamides to convert alcohols such as 17 to amides 18. A redox catalysis strategy was developed (Angew. Chem. Int. Ed. 2012, 51, 12036) by Brandon L. Ashfeld at Notre Dame for the triphenylphosphine-catalyzed Staudinger ligation of carboxylic acid 19 to furnish amide 20. For direct catalytic amidation of carboxylic acids and amines such as in the conversion of 21 to 23, Dennis G. Hall at the University of Alberta reported (J. Org. Chem. 2012, 77, 8386) that the boronic acid 22 was a highly effective catalyst that operated at room temperature.


2018 ◽  
Vol 8 (1) ◽  
pp. 9-13
Author(s):  
Nikhile Mookerji ◽  
Gurpreet Malhi

Dr. Jeff  Warren, MD, FRCPC, is an associate professor at the University of Ottawa within the Department of Surgery, Division of Urology. He has been a staff Urologist since 2009 and obtained his fellowship in multi-organ transplants, including kidneys and pancreases, from the University of Western Ontario. He received his MD from the University of Ottawa in 2002 and also completed his residency at the University of Ottawa in 2007. He is currently the head of surgical foundations for all surgical residency programs at the University of Ottawa. His clinical interests are in kidney transplantation surgery, minimally invasive surgery, and medical education. Dr. Tom Skinner, MD, FRCPC, is a transplant fellow at the University of Ottawa within the Department of Surgery, Division of Urology. He received his MD from Dalhousie University in 2012 and completed his Urology residency at Queen’s University in 2017. He has a BSc. from the University of British Columbia and a MSc. from McGill University. His clinical interests are in minimally invasive surgery, renal transplantation, surgical education, and healthcare economics. During this interview, Dr. Skinner and Dr. Warren discuss the current state of transplant surgery, the biggest challenges to transplanting patients, and the future of the specialty. They also discuss robotic surgery and the Spanish model for organ donation.


2019 ◽  
Vol 6 (1) ◽  
pp. 51-90
Author(s):  
Jaroslav Z. Skira ◽  
Myroslaw Tataryn

This essay surveys material published between 1950 and 2016 by Canadian scholars who studied Ukrainian church history and theology. Particular attention is paid to works produced by members of the Eastern-rite Redemptorist and Basilian religious orders and by scholars at St. Andrew’s College and the University of Manitoba in Winnipeg, the University of Toronto and the University of St. Michael’s College in Toronto, the Canadian Institute of Ukrainian Studies at the University of Alberta, and the Metropolitan Andrey Sheptytsky Institute of Eastern Christian Studies in Ottawa.


Author(s):  
Janet Danielson

Barbara Pentland was arguably the most rigorously modernist Canadian composer of her generation. During the late 1940s she adopted serial techniques and by the mid-1950s had forged her mature style: spare, elegantly constructed, abstract, yet with a rich timbral palette and surprising lyricism. She made adept use of new techniques throughout her career. She taught at the Royal Conservatory of Music in Toronto (1942–1949); then at the University of British Columbia (1949–1963). She received a Diplôme d’honneur from the Canadian Conference for the Arts (1977); honorary doctorates from the University of Manitoba (1976) and Simon Fraser University (1985); the Order of Canada (1989); and the Order of British Columbia (1993). Situated within the confluence of early women’s rights struggles and Canada’s search for identity at the official end of colonial rule in 1931, Pentland’s musical modernism lent authenticity and authority to her artistic voice: her music sounded neither British nor stereotypically feminine. As one reviewer observed, Pentland’s music had ‘‘that cool remoteness which conjures wide-open spaces and is probably as close to a national sound as anything Canadian composers have achieved.’’


Author(s):  
Douglass F. Taber

Stephen L. Buchwald of MIT established (J. Am. Chem. Soc. 2010, 132, 14076) a Pd-catalyzed protocol for conversion of an aryl triflate 1 to the halide 2. Jie Wu of Fudan University prepared (Tetrahedron Lett. 2010, 51, 6646) aromatic halides from the corresponding carboxylic acids. Yong-Chua Teo of Nanyang Technological University described (Tetrahedron Lett . 2010, 51, 3910) the Mn-mediated conversion of 3 to 5, suggesting a benzyne intermediate. Takanori Shibata of Waseda University effected (Synlett 2010, 2601) the direct Ru-mediated coupling of aryl halides with amines, and Paul Helquist of the University of Notre Dame prepared (J. Org. Chem. 2010, 75, 4887) anilines by coupling aryl halides with NaN3 . Chao-Jun Li of McGill University devised (Tetrahedron Lett. 2010, 51, 5486) the Pd-catalyzed decarbonylative Heck coupling of 6 with 7 to give 8. Mats Larhed of Uppsala University showed (Angew. Chem. Int. Ed. 2010, 49, 7733) that Pd could also catalyze the decarboxylative coupling of an aromatic acid 9 with a nitrile to give the ketone 10. Dennis G. Hall of the University of Alberta found (Tetrahedron Lett. 2010, 51, 4256) that an areneboronic acid could promote the Zr-catalyzed ortho condensation of a phenol 11 with an aldehyde, leading to 12, which could then be carried on to a range of other products. Professor Hall also showed (Angew. Chem. Int. Ed. 2010, 49, 2883) that areneboronic acids are stable to many standard organic transformations, and that the product boronic acids can be readily purified by extraction into sorbitol/Na2CO3. Professor Buchwald reported (J. Am. Chem. Soc. 2010, 132, 14073) an optimized source of Pd for the Suzuki-Miyaura coupling, allowing the room-temperature participation even of unstable boronic acids such as 13. Wing-Yiu Yu of the Hong Kong Polytechnic University observed (J. Am. Chem. Soc. 2010, 132, 12862) that 17 was an effective donor for the Pd-catalyzed ortho C-H amination of 16. Nicholas C. O. Tomkinson of Cardiff University uncovered (Synlett 2010, 2471) the facile rearrangement of 19 to 20. Professor Buchwald described (J. Am. Chem. Soc. 2010, 132, 9990) the coupling of 21, prepared from the aryl halide, with 22 to give the benzofuran 23.


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