Blood and plasma viscosity of winter flounder: influence of temperature, red cell concentration, and shear rate

1983 ◽  
Vol 61 (10) ◽  
pp. 2344-2350 ◽  
Author(s):  
Mark S. Graham ◽  
Garth L. Fletcher
Keyword(s):  
Shear Rate ◽  
Blood Viscosity ◽  
Cell Concentration ◽  
Plasma Viscosity ◽  
Winter Flounder ◽  
Red Cell ◽  
Pseudopleuronectes Americanus ◽  
Total Blood ◽  
Influence Of Temperature ◽  
Rate Dependent

The effects of temperature, red cell concentration, and shear rate on the viscosity of blood from the winter flounder (Pseudopleuronectes americanus) were evaluated using a cone-plate viscometer. The viscosity of blood and plasma was shear rate dependent at all temperatures studied (−1 to 20 °C) with the highest values occurring at the lowest temperature and shear rate. At normal hematocrits (20%), plasma appeared to account for at least 50% of the total blood viscosity. The effects of hematocrit on viscosity were dependent on temperature. At higher temperatures (10–20 °C), increases in hematocrit resulted in a near-exponential increase in viscosity. At lower temperatures (5 °C) and shear rates (4.5 s−1) no significant increase in viscosity occurred between hematocrits of 11 and 43%. The influence of temperature and shear rate on blood viscosity suggest that winter flounder may have to contend with a fivefold increase in blood viscosity when acclimating from summer to winter water temperatures.

Viscosity and Red Cell Deformity in Arterial Disease

1979 ◽  
Author(s):  
G Cella ◽  
H de Haas ◽  
M Rampling ◽  
V Kakkar
Keyword(s):  
Vascular Disease ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Arterial Disease ◽  
Plasma Viscosity ◽  
Control Group ◽  
Fibrinogen Concentration ◽  
Red Cell ◽  
Whole Blood Viscosity ◽  
Significant Difference

Haemorrheological factors have been shown to be affected in many kings of vascular disease. The present study was undertaken to correlate these factors in normal subjects and patients suffering from peripheral arterial disease. Twenty-two patients were investigated; they had moderate or severe intermittent claudication, extent of disease being confirmed by aorto-arteriography and ankle-systolic pressure studies. Twenty-five controls with no symptoms or signs of arterial disease were selected with comparable age and sex distribution. Whole blood viscosity was measured at shear rates of 230 secs-1 and 23 secs-lat 37°c using a Wells Brookfield cone plate microvisco meter. Plasma viscosity was also measured in an identical manner. Erythrocyte flexibility was measured by centrifuge technique and fibrinogen concentration as well as haematocrit by standard techniques. The fibrinogen concentration appeared to be the only significant parameter; the mean concentration in patients with peripheral vascular disease of 463 ± 73mg/l00ml in the control group ( < 0.05). Although whole blood viscosity was high in patients, when corrected to a common haematocrit, there was no significant difference between patients and controls. The same megative correlation was found for plasma viscosity. The red cell flexibility was found to be increased in patients as compared to the control group, but this effect appeared to be simply proportional to the fibrinogen concentration.

Viscosity and Red Cell Deformity in Arterial Disease

1979 ◽  
Author(s):  
G. Cella ◽  
H.A. de Haas ◽  
M. Rampling ◽  
V.V. Kakkar
Keyword(s):  
Vascular Disease ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Arterial Disease ◽  
Plasma Viscosity ◽  
Control Group ◽  
Fibrinogen Concentration ◽  
Red Cell ◽  
Whole Blood Viscosity ◽  
Significant Difference

Haemorrheological factors have been shown to be affected in many kings of vascular disease. The present study was undertaken to correlate these factors in normal subjects and patients suffering from peripheral arterial disease. Twenty-two patients were investigated; they had moderate or severe intermittent claudication, extent of disease being confirmed by aorto-arteriography and ankle-systolic pressure studies. Twenty-five controls with no symptoms or signs of arterial disease were selected withcomparable age and sex distribution. Whole blood viscosity was measured at shear rates of 230 secs-1 and 23 sees-1 at 37°C using a Weils Brookfield cone plate microvisco meter. Plasma viscosity was also measured in an identical manner. Erythrocyte flexibility was measured by centrifuge technique and fibrinogen concentration as well as haematocrit by standard techniques. The fibrinogen concentration appeared to be the only significant parameter; the mean concentration in patients with peripheral vascular disease of 463 ± 73mg/100ml in the control group ( 〈 0.05). Although whole blood viscosity was high in patients, when corrected t. a common haematocrit, there was no significant difference between patients and controls The same megative correlation was found for plasma viscosity. The red cell flexibility was found to be increased in patients as compared to the control group, but this effect appeared to be simply proportional to the fibrinogen concentration.

scholarly journals Blood Viscosity in Waldenström’s Macroglobulinemia

Blood ◽  
1974 ◽  
Vol 44 (1) ◽  
pp. 87-98 ◽  
Author(s):  
Mart Mannik
Keyword(s):  
Shear Rate ◽  
Newtonian Fluid ◽  
Blood Viscosity ◽  
Plasma Proteins ◽  
Plasma Viscosity ◽  
Regression Equation ◽  
Shear Rates

Abstract Erythrocytes and plasma proteins contribute to viscosity of blood. Therefore, blood viscosity was measured in 16 persons with macroglobulinemia with a cone-plate viscometer at defined shear rates. In each person a significant correlation (p < 0.001) was found between hematocrit and the logarithm of blood viscosity. The regression equation of this relationship in each patient was used to calculate the blood viscosity at several hematocrits. The blood viscosity at a given shear rate and constant hematocrit was significantly correlated (p < 0.001) with the plasma macroglobulin concentration in g/100 ml. The plasma of patients with macroglobulinemia is a non-Newtonian fluid, but at a given shear rate the plasma viscosity is a function of the macroglobulin concentration. These observations allowed the construction of an equation for calculation of blood viscosity in patients with macroglobulinemia when the hematocrit and plasma macroglobulin concentrations are known.

scholarly journals In Vitro Measurements of the Effects of Anticoagulants on the Flow Properties of Blood: The Relationship of these Effects to Red Cell Shrinkage

Blood ◽  
1968 ◽  
Vol 31 (2) ◽  
pp. 234-241 ◽  
Author(s):  
WILLIAM I. ROSENBLUM
Keyword(s):  
Cell Size ◽  
Blood Viscosity ◽  
Plasma Viscosity ◽  
Red Cell ◽  
Flow Properties ◽  
Cell Shrinkage ◽  
In Vitro Measurements ◽  
Relationship Of ◽  
The Relationship

Abstract Citrate and oxalate increased the viscosity of blood as measured in a capillary viscosimeter. The elevated viscosity was accompanied by erytrhocyte shrinkage, manifest by the decreased hematocrit of blood anticoagulated with either of these agents. Plasma viscosity was not affected. EDTA, which does not alter cell size or shape, also failed to alter blood viscosity, while citrate no longer affected viscosity, if utilized in ACD solution, a milieu which prevents cell shrinkage. When erythrocytes were suspended in hypertonic NaCl, "blood" viscosity was also elevated in comparison to that of suspensions in lower concentrations of NaCl. The data indicate that blood viscosity will be elevated by anticoagulants which are permitted to shrink erythrocytes.

Influence of Postoperative Patient-Controlled Analgesia on Hemorheology in Patients Undergoing Hip Arthroplasty

2019 ◽  
Vol 158 (01) ◽  
pp. 41-45
Author(s):  
Yiping Bai ◽  
Liqun Mo ◽  
Liming Luan ◽  
Daiying Zhang
Keyword(s):  
Shear Rate ◽  
Hip Arthroplasty ◽  
Blood Viscosity ◽  
Whole Blood ◽  
Plasma Viscosity ◽  
Erythrocyte Aggregation ◽  
Control Group ◽  
Patient Controlled Analgesia ◽  
Noninvasive Blood Pressure ◽  
Whole Blood Viscosity

Abstract Objective To test the hypothesis that patient-controlled analgesia (PCA) contributes to improvement of hemorheology in patients undergoing hip arthroplasty. Methods 120 patients, aged 60 – 75 years old, undergoing hip arthroplasty under spinal anesthesia, were randomly divided into group PCA (n = 60) and control group (n = 60). Patients in PCA group received PCA in postoperative 3 days. Blood samples from the median cubital vein were collected at five time points: before anesthesia (T1), after surgery (T2), 6 h after surgery (T3), 24 h after surgery (T4), 48 h after surgery (T5). Hemorheological parameters were measured, including whole blood viscosity at a high shear rate (Hηb), whole blood viscosity at a low shear rate (Lηb), reduced viscosity (ηr), plasma viscosity (ηp), hematocrit (Hct), erythrocyte aggregation index(EAI) and erythrocyte deformation index (EDI). Noninvasive blood pressure and heart rate at T1-5 and pain scoring of visual analogue scale (VAS) score at T2-5 were recorded. Results (1) Compared with T1, Hηb, Lηb, ηp, ηr decreased significantly at T3–5 with EAI decreased significantly at T5 in group PCA (p < 0.05), EDI increased significantly at T5 in group C (p < 0.05). (2) Compared with group C, Hηb, Lηb, ηp, ηr, EAI decreased significantly at T5 with Lηb concurrently decreased at T4 in group PCA (p < 0.05). Conclusion Postoperative pain may increase blood viscosity in patients undergoing hip arthroplasty, mainly via plasma viscosity, erythrocyte aggregation and rigidity, and which could be improved by postoperative PCA.

Blood Viscosity and Haemostasis in the Nephrotic Syndrome

1983 ◽  
Vol 49 (03) ◽  
pp. 155-157 ◽  
Author(s):  
E McGinley ◽  
G D O Lowe ◽  
M Boulton-Jones ◽  
C D Forbes ◽  
C R M Prentice
Keyword(s):  
Nephrotic Syndrome ◽  
Shear Rate ◽  
Blood Viscosity ◽  
Degradation Products ◽  
Smoking Habit ◽  
Vascular Complications ◽  
Plasma Viscosity ◽  
Control Group ◽  
Fibrin Degradation Products ◽  
Activity Factor

SummaryBlood viscosity and its major determinants (haematocrit, plasma viscosity and fibrinogen) as well as several haemostatic variables were measured in 21 patients with the nephrotic syndrome, and 21 controls matched for age, sex, smoking habit and serum creatinine. Blood viscosity was significantly increased in the nephrotic group, measured at a low shear rate (mean increase 41%, p<0.01) and at a high shear rate (mean increase 25%, p <0.01). Haematocrit was not significantly increased, but plasma viscosity was significantly higher (p <0.01), associated with increased plasma macroglobulins especially fibrinogen, which was increased to double the plasma concentration of the control group (p <0.01). Nephrotic subjects also had increased plasma levels of a2-macroglobulin, factor VIII activity, factor VIC antigen and beta-thromboglobulin; differences in antithrombin ID, fibrin degradation products, plasminogen, and platelet count were not significant.We suggest that increased blood and plasma viscosity may play a role in the vascular complications of the nephrotic syndrome.

Abnormal Blood Rheology in Young Male Diabetics with and without Retinopathy

1979 ◽  
Author(s):  
G.D.O. Lowe ◽  
M.M. Drummond ◽  
J.J.F. Belch ◽  
J.M. Lowe ◽  
A.C. MacCuish ◽  
...  
Keyword(s):  
Blood Viscosity ◽  
Smoking Habit ◽  
Vascular Complications ◽  
Young Male ◽  
Blood Rheology ◽  
Plasma Viscosity ◽  
Red Cell ◽  
Cell Deformability ◽  
Rotational Viscometer ◽  
Red Cell Deformability

We compared red cell deformability (filtration rate through 5 μ sieves), blood viscosity (rotational viscometer), haematocrit, plasma fibrinogen and plasma viscosity in young male diabetics (age <50 years) and normal controls matched for age and smoking habit. diabetics with no retinopathy or other vascular complications (n = 20) had normal red cell deformability, but increased blood viscosity at shear rates of 100s-1 (p<0.05) and is-1 (p<0. 01), due in part to moderate elevations of haematocrit, fibrinogen and plasma viscosity. Diabetics with retinopathy (n = 10) had a more marked increase in viscosity and also reduced red cell deformability (p<0.05). Increased blood viscosity is present prior to the onset of detectable vascular complications in male diabetics, while reduced red cell deformability is associated with complications.

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