Distributions of Time of Flight and Mixing Efficiency in Three-Dimensional Chaotic Advection

Author(s):  
F. Raynal ◽  
Ph. Carrière
2014 ◽  
Vol 875-877 ◽  
pp. 1189-1193 ◽  
Author(s):  
Lin Li ◽  
Qing De Chen ◽  
C.T. Tsai

Micromixer is essential component of microfluidic system which has wide application in the field of chemistry and biochemistry. A highly efficient and easily fabricated three dimensional micromixer based on chaotic advection is proposed and investigated. The depth of 25μm for each layer of micromixer and two kinds of fluids, which have viscosities of 0.00097kgm-1s-1and 0.186kgm-1s-1with Re number from 0.001 to 150, are adopted for numerical investigation of mixing efficiency by using ANSYS-Fluent. High mixing index of more than 90% can be obtained by using less than 300μm of length under Re number of 0.01 for mixing Fluid 1. However, it requires 850μm to achieve mixing index of more than 90% for hard-to-mix Fluid 2.


2015 ◽  
Vol 27 (4) ◽  
pp. 043601 ◽  
Author(s):  
Florence Raynal ◽  
Philippe Carrière

Author(s):  
Hua Yang ◽  
Shi-Xiao Wei ◽  
Han Chen ◽  
Lang Chen ◽  
Chak-tong Au ◽  
...  

Owing to high mixing efficiency, microreactors are used to synthesize uniform BaSO4 nanoparticles, but application in industrial scale is limited due to poor throughput. In this work, a high-throughput passive four-stage asymmetric oscillating feedback microreactor using chaotic mixing mechanism was developed to prepare BaSO4 nanoparticles of high size uniformity. Three-dimensional unsteady simulations showed that chaotic mixing could be induced by three unique secondary flows (i.e., vortex, recirculation, and oscillation), and the fluid oscillation mechanism was examined in detail. Simulations and Villermaux-Dushman experiments indicate that almost complete mixing in molecular level could be achieved when total volumetric flow rate Qtotal was larger than 10 mL/min, and the prepared BaSO4 nanoparticles were with narrow particle size distribution (PSD). Through the adjustment of Qtotal and reactant concentrations, it is easy to control the average size. An average size of 26 nm with narrow PSD could be achieved at Qtotal = 160 mL/min.


2021 ◽  
Vol 11 (8) ◽  
pp. 3404
Author(s):  
Majid Hejazian ◽  
Eugeniu Balaur ◽  
Brian Abbey

Microfluidic devices which integrate both rapid mixing and liquid jetting for sample delivery are an emerging solution for studying molecular dynamics via X-ray diffraction. Here we use finite element modelling to investigate the efficiency and time-resolution achievable using microfluidic mixers within the parameter range required for producing stable liquid jets. Three-dimensional simulations, validated by experimental data, are used to determine the velocity and concentration distribution within these devices. The results show that by adopting a serpentine geometry, it is possible to induce chaotic mixing, which effectively reduces the time required to achieve a homogeneous mixture for sample delivery. Further, we investigate the effect of flow rate and the mixer microchannel size on the mixing efficiency and minimum time required for complete mixing of the two solutions whilst maintaining a stable jet. In general, we find that the smaller the cross-sectional area of the mixer microchannel, the shorter the time needed to achieve homogeneous mixing for a given flow rate. The results of these simulations will form the basis for optimised designs enabling the study of molecular dynamics occurring on millisecond timescales using integrated mix-and-inject microfluidic devices.


Author(s):  
Daphne Schönegg ◽  
Raphael Ferrari ◽  
Julian Ebner ◽  
Michael Blumer ◽  
Martin Lanzer ◽  
...  

Abstract Purpose The close topographic relationship between vascular and osseous structures in the condylar and subcondylar region and marked variability in the arterial course has been revealed by both imaging and cadaveric studies. This study aimed to verify the previously published information in a large sample and to determine a safe surgical region. Methods We analyzed the three-dimensional time-of-flight magnetic resonance angiography images of 300 individuals. Results The mean distance between the middle meningeal artery and the apex of the condyle or the most medial point of the condyle was 18.8 mm (range: 11.2–25.9 mm) or 14.5 mm (range: 8.8–22.9 mm) respectively. The course of the maxillary artery relative to the lateral pterygoid muscle was medial in 45.7% of cases and lateral in 54.3%. An asymmetric course was evident in 66 patients (22%). The mean distance between the maxillary artery and condylar process at the deepest point of the mandibular notch was 6.2 mm in sides exhibiting a medial course (range: 3.7–9.8 mm) and 6.6 mm in sides exhibiting a lateral course (range: 3.9–10.4 mm). The distances were significantly influenced by age, gender, and the course of the maxillary artery. Conclusion Our study emphasizes the marked inter- and intra-individual variability of the maxillary and middle meningeal arterial courses. We confirmed the proximity of the arteries to the condylar process. Extensive surgical experience and thorough preparation for each individual case are essential to prevent iatrogenic vascular injury.


2017 ◽  
Vol 7 (1) ◽  
Author(s):  
Alberto Cereser ◽  
Markus Strobl ◽  
Stephen A. Hall ◽  
Axel Steuwer ◽  
Ryoji Kiyanagi ◽  
...  

2017 ◽  
Vol 825 ◽  
pp. 631-650 ◽  
Author(s):  
Francesco Romanò ◽  
Arash Hajisharifi ◽  
Hendrik C. Kuhlmann

The topology of the incompressible steady three-dimensional flow in a partially filled cylindrical rotating drum, infinitely extended along its axis, is investigated numerically for a ratio of pool depth to radius of 0.2. In the limit of vanishing Froude and capillary numbers, the liquid–gas interface remains flat and the two-dimensional flow becomes unstable to steady three-dimensional convection cells. The Lagrangian transport in the cellular flow is organised by periodic spiralling-in and spiralling-out saddle foci, and by saddle limit cycles. Chaotic advection is caused by a breakup of a degenerate heteroclinic connection between the two saddle foci when the flow becomes three-dimensional. On increasing the Reynolds number, chaotic streamlines invade the cells from the cell boundary and from the interior along the broken heteroclinic connection. This trend is made evident by computing the Kolmogorov–Arnold–Moser tori for five supercritical Reynolds numbers.


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