Acupuncture Application in Chronic Kidney Disease and its Potential Mechanisms

2018 ◽  
Vol 46 (06) ◽  
pp. 1169-1185 ◽  
Author(s):  
Wei Xiong ◽  
Fang-Fang He ◽  
Ren-Yu You ◽  
Jing Xiong ◽  
Yu-Mei Wang ◽  
...  
Keyword(s):  
Public Health ◽  
Chronic Kidney Disease ◽  
Renal Function ◽  
Chinese Medicine ◽  
Kidney Disease ◽  
Traditional Chinese Medicine ◽  
Public Health Problem ◽  
Therapeutic Effects ◽  
Major Public Health Problem ◽  
Uremic Pruritus

Chronic kidney disease (CKD) is an increasing major public health problem worldwide. The number of CKD patients on hemodialysis is growing rapidly as well. Acupuncture technique is one of the traditional Chinese medicine methods and has been used in a variety of diseases. Nowadays, the clinical application of acupuncture technique for CKD patients has become the focus for its effectiveness and security. In this paper, we will review the therapeutic effects and mechanisms of different acupuncture techniques for CKD patients. In patients with CKD, acupuncture improves renal function, reduces proteinuria, controls hypertension, corrects anemia, relieves pain, and controls many hemodialysis-related complications such as uremic pruritus, insomnia and fatigue. The mechanisms are related to the regulation of sympathetic nerve and the activation of bioactive chemicals. In conclusion, acupuncture is proved to be beneficial for CKD patients. More research, however, is needed to verify the potential mechanisms.

scholarly journals Chronic Kidney Disease, Obesity, and Hypertension: The Role of Leptin and Adiponectin

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
M. Tesauro ◽  
A. Mascali ◽  
O. Franzese ◽  
S. Cipriani ◽  
C. Cardillo ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Renal Function ◽  
Kidney Disease ◽  
Kidney Injury ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Renal Progression ◽  
Obesity Hypertension ◽  
Progression Factor

Chronic kidney disease is a major public health problem and characterized by a progressive loss in renal function over a period of months or years as defined by structural or functional abnormalities of the kidney. Several elements contribute to determine a progression of the kidney injury, inducing a worsening of renal damage and accelerating the decline of renal function: obesity and hypertension are two known factors of kidney progression. Remarkable improvements have been recently achieved in the study of the endocrine features of the adipose tissue and have been able to produce hormone-like peptides named adipokines or adipocytokines. Among these adipocytokines, which represent a link between obesity, hypertension, and chronic nephropathy, leptins and adiponectin appear to play an important role. Leptin not only is a prohypertension element (renal progression factor) through the activation sympathetic nervous, but also is able to induce prosclerotic effects directly on the kidney. In contrast, a decline of adiponectin levels has been shown to be related to a picture of hypertension: an endothelial dysfunction has been described as the main pathogenic mechanism responsible for this phenomenon.

scholarly journals Projecting the Burden of Chronic Kidney Disease in a Developed Country and Its Implications on Public Health

2018 ◽  
Vol 2018 ◽  
pp. 1-9 ◽  
Author(s):  
L. Y. Wong ◽  
A. S. T. Liew ◽  
W. T. Weng ◽  
C. K. Lim ◽  
A. Vathsala ◽  
...  
Keyword(s):  
Public Health ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Markov Model ◽  
Public Health Problem ◽  
Disease Detection ◽  
Time Interval ◽  
Major Public Health Problem ◽  
Health States ◽  
Detection Rates

Background. Chronic Kidney Disease (CKD) is a major public health problem worldwide. There is limited literature on a model to project the number of people with CKD. This study projects the number of residents with CKD in Singapore by 2035 using a Markov model. Methods. A Markov model with nine mutually exclusive health states was developed according to the clinical course of CKD, based on a discrete time interval of 1 year. The model simulated the transition of cohorts across different health states from 2007 to 2035 using prevalence, incidence, mortality, disease transition, and disease detection rates. Results. From 2007 to 2035, the number of residents with CKD is projected to increase from 316,521 to 887,870 and the prevalence from 12.2% to 24.3%. Patients with CKD stages 1-2 constituted the largest proportion. The proportion of undiagnosed cases will decline from 72.1% to 56.4%, resulting from faster progression to higher CKD stages and its eventual detection. Conclusion. By 2035, about one-quarter of the Singapore residents are expected to have CKD. National policies need to focus on primary disease prevention and early disease detection to avoid delayed treatment of CKD which eventually leads to end-stage renal disease.

scholarly journals Fever and Antipyretic Supported by Traditional Chinese Medicine: A Multi-Pathway Regulation

2021 ◽  
Vol 12 ◽  
Author(s):  
Le-Le Ma ◽  
Hui-Min Liu ◽  
Chuan-Hong Luo ◽  
Ya-Nan He ◽  
Fang Wang ◽  
...  
Keyword(s):  
Chinese Medicine ◽  
Traditional Chinese Medicine ◽  
Clinical Symptoms ◽  
Signal Transmission ◽  
Public Health Problem ◽  
Pharmacological Action ◽  
Major Public Health Problem ◽  
Neural Pathways ◽  
The World ◽  
In Series

The coronavirus disease, 2019 (COVID-19), has spread rapidly around the world and become a major public health problem facing the world. Traditional Chinese medicine (TCM) has been fully committed to treat COVID-19 in China. It improved the clinical symptoms of patients and reduced the mortality rate. In light of the fever was identified as one of leading clinical features of COVID-19, this paper will first analyze the material basis of fever, including pyrogenic cytokines and a variety of the mediators of fever. Then the humoral and neural pathways of fever signal transmission will be described. The scattered evidences about fever recorded in recent years are connected in series. On this basis, the understanding of fever is further deepened from the aspects of pathology and physiology. Finally, combining with the chemical composition and pharmacological action of available TCM, we analyzed the mechanisms of TCMs to play the antipyretic effect through multiple ways. So as to further provide the basis for the research of antipyretic compound preparations of TCMs and explore the potential medicines for the prevention and treatment of COVID-19.

Association between Serum Asymetrical Dimethylarginine Level and Cardiac Functions in Chronic kidney Disease Patients

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Saeed Abdelwahab Saeed ◽  
Ashraf Hassan Abd-elmobdy ◽  
Mostafa Ashour Mahmoud Farag Ammar
Keyword(s):  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Diastolic Function ◽  
Tissue Doppler Imaging ◽  
Public Health Problem ◽  
Tissue Doppler ◽  
Doppler Imaging ◽  
Major Public Health Problem ◽  
Cardiac Functions ◽  
Laboratory Investigations

Abstract Background Chronic kidney disease (CKD) is a major public health problem worldwide and is associated with a considerable increase in morbidity and mortality, cardiovascular disease is most common cause of death among chronic kidney disease patients. Objectives The aim of study was to determine the association between serum ADMA level and cardiac functions assessed by tissue Doppler imaging in chronic kidney disease patients. Patients and Methods our study conducted on 90 patients from outpatient clinic or inpatient department of national institute of nephrology and urology. Results All patients were subjected to full history, full clinical examination, laboratory investigations including: serum urea, serum albumin, complete blood picture, serum electrolytes (calcium and phosphorus), PTH, serum ADMA, lipid profile and echocardiography and Tissue Doppler imaging. Conclusion Serum ADMA is negatively correlated with diastolic function among CKD patients, tissue Doppler imaging is more accurate than echocardiography to estimate diastolic function.

scholarly journals Prevalence, risk-inducing lifestyle, and perceived susceptibility to kidney diseases by gender among Nigerians residents in South Western Nigeria

2020 ◽  
Vol 20 (2) ◽  
pp. 860-870
Author(s):  
Monica Ewomazino Akokuwebe ◽  
Clifford Odimegwu ◽  
Femi Omololu
Keyword(s):  
Public Health ◽  
Risk Factors ◽  
Kidney Disease ◽  
Lifestyle Modification ◽  
Disease Risk ◽  
Kidney Diseases ◽  
Public Health Problem ◽  
Major Public Health Problem ◽  
Perceived Susceptibility ◽  
Female Ratio

Background: Kidney disease (KD) is increasingly recognized as a major public health problem worldwide with rising inci- dence and prevalence. Early identification of KD risk factors will slow down progression to kidney failure and death. Objective: To determine the prevalence, risk-inducing lifestyle and perceived susceptibility among Nigerians in South-west- ern Nigeria. Methods: A pretested structured questionnaire was employed to draw information on socio-demographic, knowledge, risk-inducing lifestyle and perceived susceptibility to conventional risk factors of KD from 1757 residents aged ≥15 years. Results: The mean age of the respondents was 47.61±13.0 years with a male-female ratio of 1.13:1. Knowledge of KD was low (mean score 2.29; 95% CI: 2.18, 2.32). The prevalence of some established KD risk factors was regular use of herbal medications, 26.8% and physical inactivity, 70.0%. Females with factors such as use of herbal drink [RRR: 1.56; CI=1.06- 2.30; p=0.02] and smoking [RRR: 2.72; CI=1.37-5.37; p=0.00] predicted increased odds of perceived susceptibility to KD than their male counterparts. Conclusion: The prevalence of KD risk-inducing lifestyles was high. More emphasis should be placed on effective public health programmes towards behavioural change in order to adopt lifestyle modification as well as to reduce the tendency to develop KD. Keywords: Kidney disease; risk-inducing lifestyles; perceived susceptibility.

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