BIOBOARD

2019 ◽  
Vol 23 (03) ◽  
pp. 39-44
Keyword(s):  
Type 2 Diabetes ◽  
Influenza Vaccine ◽  
Human Nutrition ◽  
Protein Source ◽  
Asia Pacific ◽  
Tropical Waters ◽  
Glucose Levels ◽  
The World

ASIA-PACIFIC – Quality and quantity of sleep affects behavior, cognition and glucose levels in Asian teens. ASIA-PACIFIC – Quality of overall diet key to lowering type 2 diabetes risk. ASIA-PACIFIC – Toxic bacteria found on microplastics retrieved from tropical waters. ASIA-PACIFIC – New use of anti-parasitic drug to potentially treat cancer. ASIA-PACIFIC – Hassle free influenza vaccine close to reality. REST OF THE WORLD – Bitter rapeseed could be used as protein source for human nutrition.

scholarly journals Effects of Social Determinants of Health in Progression to Type 2 Diabetes

2021 ◽  
Author(s):  
◽  
Folabi Ariganjoye ◽  
Keyword(s):  
Quality Of Life ◽  
United States ◽  
Type 2 Diabetes ◽  
Social Determinants ◽  
The United States ◽  
Effective Management ◽  
The World ◽  
Longitudinal Association

The prevalence of prediabetes and diabetes in the United States and around the world has increased faster than expected in the last 30 years. The economic burden this costs a nation can be astronomic both in terms of expense and loss in productivity. One-third of U.S. adults, 86 million people, have prediabetes. Effective management is needed that can reach these 86 million, and others at high risk, to reduce their progression to diagnosed Type 2 diabetes. After the literature review, there was not enough literature to support how these led to the progression to diabetes. The abundant literature is centered on how to prevent complications and improve the quality of life of those living with type 2 diabetes. This paper will focus on the longitudinal association between these social determinants and how they may predispose to the progression to Type 2 diabetes.

scholarly journals The Patients at High Risk of Type 2 Diabetes Development

2020 ◽  
Vol 16 (26) ◽  
pp. 50-55
Author(s):  
Е.V. Ivannikova ◽  
◽  
O.M. Smirnova
Keyword(s):  
Quality Of Life ◽  
Type 2 Diabetes ◽  
Risk Groups ◽  
Poor Quality ◽  
Glucose Levels ◽  
Blood Glucose Levels ◽  
Diabetes Development ◽  
Methods Of Treatment

Prediabetes is defined as a state of abnormal glucose homeostasis where blood glucose levels are elevated above those considered normal, but not as high as those required for a diagnosis of diabetes. Prediabetes is associated with high risks of developing serious diseases and poor quality of life of the patient. Globally, there are about 352.1 million people with prediabetes. By 2045, the number of able-bodied patients with a similar diagnosis is expected to double to 587 million. In this connection, timely diagnosis and identification of risk groups for the correction of carbohydrate metabolism is of great importance. The article provides data from numerous studies, a description of tactics and methods of treatment for patients with prediabetes.

scholarly journals Comparing effects of continuous glucose monitoring systems (CGMs) and self monitoring of blood glucose (SMBG) among adults with type 2 diabetes mellitus: A systematic review protocol

2020 ◽  
Author(s):  
Mingyue Zheng ◽  
Yunting Luo ◽  
Wei Lin ◽  
Adeel Khoja ◽  
Qian He ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Type 2 Diabetes ◽  
Blood Glucose ◽  
Glucose Control ◽  
Diabetes Management ◽  
Self Monitoring ◽  
Glucose Levels

Abstract Background: Continuous glucose monitors (CGMs) have been used to manage diabetes with reasonable glucose control among patients with type 2 diabetes (T2D) in recent decades. CGM systems measure interstitial fluid glucose levels to provide information about glucose levels, which identifies fluctuation that would not have been identified with conventional self-monitoring. Self-monitoring of blood glucose (SMBG) is a classical tool to achieve glycaemic control. However, the effectiveness of glucose control, costs, and quality of life are needed to evaluate and compare CGM and SMBG among adults with T2D.Methods: The review will compare the various forms of CGM systems (i.e flash-CGM, real-time-CGM, retrospective-CGM) versus SMBG/usual intervention regarding diabetes management among adults with T2D. The following databases will be searched: Cochrane Library, Science Direct, PubMed, EMBASE, CINAHL, PsycINFO, Scopus and grey literature for the identification of studies. The studies involving adults (aged ≥ 18 years old) will be included. We will include and summararize randomised clinical trials (RCTs) with respect to authors, publication type, year, status, and type of devices. Studies published in English between February 2010 and March 2020 will be included as the field of CGMs among T2D patients has emerged over the last decade. Primary outcomes that will be measured will be; HbA1c, body weight, time spent with hypoglycaemia or hyperglycaemia, blood pressure, quality of life. Secondary outcome measured will be morbidity, all-cause mortality, user satisfaction, and barriers. Study selection, data extraction, and risk of bias assessment will be conducted independently by at least two authors. A third author will determine and resolve discrepancies. Moreover, the quality of the evidence of the review will be assessed according to the Grading of Recommendations Assessment, Development and Evaluation Tool (GRADE).Discussion: The systematic review will synthesise evidence on the comparison between using CGMs and SMBG. The results will support researchers and health care professionals to determine the most effective methods/technologies in the overall diabetes management. Moreover, this review will provide more detailed information about the barriers of using CGMs to improve implementation.Systematic review registration: PROSPERO CRD42020149212

scholarly journals Mechanisms of macro-, micro- and ultramicroscopic transformation of bodies in diabetes

Morphologia ◽  
2021 ◽  
Vol 15 (3) ◽  
pp. 23-29
Author(s):  
I.I. Savka ◽  
M.N. Tsytovskyi ◽  
G.M. Dmytriv
Keyword(s):  
Quality Of Life ◽  
Type 2 Diabetes ◽  
Diabetes Type 2 ◽  
Diabetes Type ◽  
Clinical Aspects ◽  
Number Of Patients ◽  
The World ◽  
Patients With Diabetes

The study of structural changes of organs and tissues in the context of diabetes is one of the urgent problems of modern medicine. According to WHO, in all countries of the world the number of patients with diabetes exceeds 175 million. According to an expert estimate of the spread of this disease by 2025 will make about 300 million people. More than 1 million people with diabetes have been officially registered in Ukraine. WHO has recognized the disease as a non-communicable epidemic. The dramatic increase in the prevalence of diabetes requires a detailed study of this problem. It is established that the prevalence of diabetes increases among the population of the countries of the world depending on the region, the level of economic development of the country, gender and age. Thus, according to IDF findings, there is a tendency for the highest prevalence of diabetes among the urban (urban) able-bodied population of developing countries in persons between 40 and 59 years of age, approximately equal in both male and female. The number of patients is increasing, mainly due to patients with type 2 diabetes. Type 2 diabetes (type 2 diabetes mellitus) is a severe progressive chronic disease that is an independent risk factor for heart failure (CH) and cardiovascular complications. In the XXI century. the steady growth of type 2 diabetes and the frequency of its serious consequences is of great concern to the world medical community. It is important that at the time of diagnosis of type 2 diabetes, the prevalence of complications leading to a decline in quality of life, early disability and premature death is already high enough. Despite the presence in the fight against this disease effective drugs, modern technologies, new educational and preventive techniques, mankind loses the fight against diabetes year after year, which leads to disability due to its complications, reducing the life expectancy and quality of life of patients, loss working capacity and premature mortality. Thus, the current prevalence and incidence of diabetes and life-threatening complications suggest that there is a non-communicable diabetes epidemic in the world and in Ukraine in particular. The article represents analysis of work of numerous researchers who studied statistіcal, clinical and morphological aspects of the impact of diabetes on cardiovascular system. Main morphogenetic, morphological and clinical aspects of complications of diabetes, pathologies of microcirculation of patients with diabetes were dedicated, what makes possible to predict and detect on the early stages vascular complications in diabetes and to perform effective prevention and treatment.

scholarly journals A First Attempt to Identify Repurposable Drugs for Type 2 Diabetes: 3D-Similarity Search and Molecular Docking

2020 ◽  
Vol 3 (1) ◽  
pp. 7
Author(s):  
Daniela Istrate ◽  
Alina Bora ◽  
Luminita Crisan
Keyword(s):  
Type 2 Diabetes ◽  
Similarity Search ◽  
Drug Repositioning ◽  
New Drugs ◽  
Dipeptidyl Peptidase 4 ◽  
The World ◽  
3D Similarity ◽  
Antidiabetic Effects

Drug repositioning involves the investigation of existing drugs for new therapeutic purposes, such as type 2 diabetes. This disease affects the health and quality of life for individuals around the world. Sitagliptin, a highly selective dipeptidyl peptidase-4 (DPP-4) inhibitor, is used to treat type 2 diabetes mellitus by effective fasting and improved glycemic control. Despite this advantage, serious hypersensitivity reactions have been acknowledged for patients receiving sitagliptin. In this context, it is necessary to develop new drugs with enhanced profiles and targeting DPP-4. Sitagliptin, ((2R)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihidro[1,2,4]triazolo[4,3-A]pirazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)butan-2-amine), was used as a query in a 3D-similarity search on the approved DrugBank. Based on the TanimotoCombo parameter, the first 10 approved DrugBank drugs were docked in the 4FFW active site to identify effective antidiabetic effects for possible repurposable drugs marketed with other indications.

scholarly journals PENGARUH DUKUNGAN SOSIAL DAN KELUARGA TERHADAP KUALITAS HIDUP PASIEN DM TIPE 2 DI WILAYAH KERJA PUSKESMAS MANGASA KOTA MAKASSAR

2019 ◽  
Vol 10 (2) ◽  
pp. 121
Author(s):  
Maryati Tombokan ◽  
Muh. Ardi ◽  
Novi Desriyani
Keyword(s):  
Quality Of Life ◽  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Family Support ◽  
Family Influence ◽  
Cross Sectional ◽  
Glucose Levels ◽  
Blood Glucose Levels

ABSTRACTDiabetes mellitus is an abnormality of insulin secretion, insulin action, or both of which are marked by an increase in blood glucose levels or hyperglycemia. Various problems caused by diabetes mellitus often make individuals experience excessive anxiety, this can affect the quality of life.The purpose of this study was to determine the effect of social and family support on the quality of life of patients with type 2 diabetes mellitus in the working area of Mangasa Health Center in Makassar City. The research method uses descriptive analytic with cross sectiona technique approach. The results of the study using unpaired t test showed that there is a social influence sampling on quality of life (p = 0.02), and there is a family influence on quality of life (p = 0.01). The conclusion from the results of the study is that there is an influence of social and family support on the quality of life of patients with type 2 diabetes mellitus.Keywords : Diabetes mellitus, social and family support, quality of life ABSTRAK Diabetes mellitus merupakan kelainan sekresi insulin, kerja insulin, atau keduanya yang ditandai dengan kenaikan kadar glukosa darah atau hiperglikemia. Berbagai masalah yang disebabkan oleh diabetes mellitus seringkali membuat individu mengalami kecemasan yang berlebihan, hal ini dapat mempengaruhi kualtas hidupnya. Tujuan penelitian untuk mengetahui pengaruh dukungan sosial dan keluarga terhadap kualitas hidup pasien diabete mellitus tipe 2 di wilayah kerja Puskesmas Mangasa Kota Makassar. Metode penelitian menggunakan descriptive analytic dengan pendekatan cross sectional. Hasil penelitian dengan menggunakan uji t tidak berpasangan menunjukkan bahwa ada pengaruh dukungan sosial terhadap kualitas hidup (p = 0,02), dan ada pengaruh dukungan keluarga terhadap kualitas hidup (p = 0,01). Kesimpulan dari hasil penelitian ini adalah ada pengaruh dukungan sosial dan keluarga terhadap kualitas hidup pasien diabetes mellitus tipe 2. Kata kunci : Diabetes mellitus, dukungan sosial dan keluarga, kualitas hidup

Sign in / Sign up

Export Citation Format

Share Document