Ontology Versioning Driven by Instance Evolution in the τOWL Framework

Author(s):  
Zouhaier Brahmia ◽  
Fabio Grandi ◽  
Abir Zekri ◽  
Rafik Bouaziz

Like other components of Semantic Web-based applications, ontologies are evolving over time to reflect changes in the real world. Several of these applications require keeping a full-fledged history of ontology changes so that both ontology instance versions and their corresponding ontology schema versions are maintained. Updates to an ontology instance could be non-conservative that is leading to a new ontology instance version no longer conforming to the current ontology schema version. If, for some reasons, a non-conservative update has to be executed, in spite of its consequence, it requires the production of a new ontology schema version to which the new ontology instance version is conformant so that the new ontology version produced by the update is globally consistent. In this paper, we first propose an approach that supports ontology schema changes which are triggered by non-conservative updates to ontology instances and, thus, gives rise to an ontology schema versioning driven by instance updates. Note that in an engineering perspective, such an approach can be used as an incremental ontology construction method driven by the modification of instance data, whose exact structure may not be completely known at the initial design time. After that, we apply our proposal to the already established [Formula: see text]OWL (Temporal OWL 2) framework, which allows defining and evolving temporal OWL 2 ontologies in an environment that supports temporal versioning of both ontology instances and ontology schemas, by extending it to also support the management of non-conservative updates to ontology instance versions. Last, we show the feasibility of our approach by dealing with its implementation within a new release of the [Formula: see text] OWL-Manager tool.

Author(s):  
Stephen Verderber

The interdisciplinary field of person-environment relations has, from its origins, addressed the transactional relationship between human behavior and the built environment. This body of knowledge has been based upon qualitative and quantitative assessment of phenomena in the “real world.” This knowledge base has been instrumental in advancing the quality of real, physical environments globally at various scales of inquiry and with myriad user/client constituencies. By contrast, scant attention has been devoted to using simulation as a means to examine and represent person-environment transactions and how what is learned can be applied. The present discussion posits that press-competency theory, with related aspects drawn from functionalist-evolutionary theory, can together function to help us learn of how the medium of film can yield further insights to person-environment (P-E) transactions in the real world. Sampling, combined with extemporary behavior setting analysis, provide the basis for this analysis of healthcare settings as expressed throughout the history of cinema. This method can be of significant aid in examining P-E transactions across diverse historical periods, building types and places, healthcare and otherwise, otherwise logistically, geographically, or temporally unattainable in real time and space.


2012 ◽  
Vol 127 (5) ◽  
pp. 373-380 ◽  
Author(s):  
G. Parker ◽  
K. Fletcher ◽  
B. Blanch ◽  
L. Greenfield

2020 ◽  
Vol 35 (Supplement_3) ◽  
Author(s):  
Michael J Germain ◽  
Subir K Paul ◽  
Varshasb Broumand ◽  
George Fadda ◽  
Andy Nguyen ◽  
...  

Abstract Background and Aims Extended-release calcifediol (ERC), active vitamin D analogs (VDA), and nutritional vitamin D (NVD) are the predominant vitamin D therapies (VDTs) commonly used for treatment (Tx) of secondary hyperparathyroidism (SHPT) in adults with stage 3 or 4 non-dialysis chronic kidney disease (ND-CKD) and vitamin D insufficiency (VDI). Clinical trials have demonstrated varying efficacy on serum total 25-hydroxyvitamin D (25D) and intact parathyroid hormone (iPTH) across VDTs. This study aimed to descriptively assess the real-world experience of various VDTs in increasing 25D, reducing iPTH, and modifying serum calcium (Ca). Method Medical records of the first 376 adult patients with stage 3 or 4 CKD and a history of SHPT and VDI who met study criteria from 18 geographically representative United States nephrology clinics were reviewed from 1 year before through 1 year after initiation of VDT. Key study variables included patient demographics, medication usage, and laboratory results. The study population had a mean age of 69.5 years with gender and racial distributions representative of the US ND-CKD population. Patients were stratified into cohorts based on their index therapy at index date: ERC (n=174), VDA (n=55) and NVD (n=147). Results Patients treated with NVD were predominantly CKD Stage 3 (69.4%), while CKD Stage 4 were the majority of those treated with ERC (53.4%) and VDA (61.8%). The ERC Tx’ed subjects demonstrated an increase in 25D by 23.7 ± 1.6 ng/mL (p<0.001) and a decrease iPTH by 35 ± 6.2 pg/mL (p<0.001) without statistically significant impact on serum calcium (Ca) and phosphorus (P) levels. The VDA Tx’ed group demonstrated an increase in 25D by 5.5 ± 1.3 ng/mL (p<0.001) without statistically significant impact on iPTH and serum phosphorus levels. Additionally, serum Ca increased by 0.2 ± 0.1 pg/mL (p<0.001) among VDA recipients. The NVD Tx’ed group demonstrated an increase in 25D by 9.7 ± 1.6 ng/mL (p<0.001) without statistically significant impact on iPTH and serum Ca and P levels (Table 1). Conclusion Clinical effectiveness and safety varied across VDTs. ERC was the only VDT which significantly reduced mean iPTH in the real world setting despite highest mean levels at baseline among the three cohorts. Additionally, subjects treated with ERC demonstrated the largest mean increase in 25D and ERC was the only VDT which raised mean 25D to the normal range (>30 ng/mL). Patients treated with ERC and NVD saw no statistically significant impact on serum Ca and P levels; however, those treated with VDAs saw a small, but statistically significant increase in serum Ca levels.


1970 ◽  
Vol 4 (1) ◽  
Author(s):  
Richard L Gilbert

The P.R.O.S.E. (Psychological Research on Synthetic Environments) Project was established to investigate the psychology of 3D virtual worlds. Under the auspices of the project, a systematic program of in-world behavioral research is being conducted that addresses three core questions related to the psychology of 3D immersive environments: What are the characteristics of active participants in virtual worlds? Do the principles of psychology that operate in the real world also apply to the virtual world? Do experiences in the virtual world have the capacity to influence behavior and subjective experience in the real world? The current paper describes a series of studies that examine each of these questions and outlines future directions for the project. If projections for a highly populated, ubiquitously accessible (web-based), and seamlessly integrated (interoperable) network of virtual worlds are borne out, a new realm of psychological reality and interaction will have been created that will be increasingly important for behavioral scientists to investigate and understand.


2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e24112-e24112
Author(s):  
Safiya Karim ◽  
Sasha M. Lupichuk ◽  
Amy Tan ◽  
Aynharan Sinnarajah ◽  
Jessica Simon

e24112 Background: The Serious Illness Care Program (SICP) is a system-based intervention, including a conversation guide, which facilitates improved advance care planning (ACP) conversations between clinicians and seriously ill patients. A recent randomized control trial found the program reduced symptoms of depression and anxiety amongst oncology out-patients and improved process outcomes. We implemented the SICP in our center to determine if the effects of this program could be translated into the real world. Methods: Two outpatient oncology clinics implemented the SICP, each over a 16-week period. Patients were identified based on an answer of “no” to the question “would I be surprised if this patient died within the next year?”, or any patient with a diagnosis of metastatic pancreatic cancer, or symptom scores of > 7 on more than three categories of the patient reported outcome dashboard. Physicians were trained on how to conduct the SICP conversation. One patient per week was identified and prepared to have the SICP conversation with the goal of at least 12 conversations in each 16-week period. Rates of SICP conversation documentation on our system’s “ACP and goals of care designation (GCD) Tracking Record” and GCD orders were recorded. Patient satisfaction after each conversation and physician comfort level over time were assessed. Results: 16 patients were identified (8 patients in each 16-week period). One patient was lost to follow-up. Of the remaining 15 patients who had the SICP conversation, 14 (93%) had documentation on the Tracking Record and 8 (53%) had a GCD order. This was a major improvement over baseline rates of documentation (e.g. < 1 % Tracking Record use and 16% GCD for patients with GI cancers). 14 patients completed satisfaction surveys, of which 12 (86%) felt “completely” or “quite a bit” more heard or understood. Physician comfort level increased from 3.6 to 4.8 and from 4.8 to 5 out of 5, respectively over each 16-week period. Conclusions: SICP implementation resulted in high rates of documentation of goals and preferences. Patients felt heard and understood by their healthcare team, and comfort in these conversations improved over time for physicians. The goal number of conversations was not met, but otherwise the SICP was feasible to implement in the real world. Further study is required to identify the appropriate triggers and barriers to routine SICP conversations.


1986 ◽  
Vol 13 (1) ◽  
pp. 114 ◽  
Author(s):  
Marian C. Burke ◽  
Julie A. Edell
Keyword(s):  
The Real ◽  

10.1068/d280t ◽  
2003 ◽  
Vol 21 (1) ◽  
pp. 67-84 ◽  
Author(s):  
Richard G Smith
Keyword(s):  
The Real ◽  

Can we burn the signs and journey without maps? In other words, can we travel from representational theories, through Baudrillard's critique of representation, to forms of theory that are somehow nonrepresentational? In this paper I hijack and go beyond Baudrillard's concepts of the precession and orders of simulacra to illustrate two main things: first, how the history of geographical thought has been one of representational theory, where there was seen to be a relationship, and then commutation, of theory and the real world; second, how representational theories are perhaps out of tune, unable to explain adequately, or change, our digital and commodity—sign soaked culture of simulacra, simulations, and reproductions. Overall, I attempt to show clearly how, through his poststructuralist critique of representation, Baudrillard is challenging us to rethink theory as doubly nonrepresentational.


Author(s):  
Matteo Casu ◽  
Luca Albergante

The notion of identity has been discussed extensively in the past. Leibniz was the first to present this notion in a logically coherent way, using a formulation generally recognized as “Leibniz's Law”. Although some authors criticized this formulation, Leibniz's Law is generally accepted as the definition of identity. This work interprets Leibniz's Law as a limit notion: perfectly reasonable in a <i>God's eye</i> view of reality, but very difficult to use in the real world because of the limitedness of finite agents. To illustrate our approach we use “description logics” to describe the properties of objects, and present an approach to relativize Leibniz's Law. This relativization is further developed in a semantic web context, where the utility of our approach is suggested.


Author(s):  
Robert H. Swendsen

The phenomenon of irreversibility is explained on the basis of an analysis by H. L. Frisch. The history of the debate over irreversibility is briefly discussed, including Boltzmann’s H-theorem, Zermelo's Wiederkehreinwand, Poincaré recurrences, Loschmidt's Umkehreinwand and Liouville’s theorem. The derivation of irreversible behavior for the ideal gas position distribution is carried out explicitly. Using this derivation, the Wiederkehreinwand and the Umkehreinwand are revisited and explained. The first thing we must establish is the meaning of the term ‘irreversibility’. This is not quite as trivial as it might seem. The irreversible behavior I will try to explain is that which is observed. Every day we see that time runs in only one direction in the real world,.


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