scholarly journals Effect of exercise therapy combined with branched-chain amino acid supplementation on muscle strengthening in persons with osteoarthritis

2018 ◽  
Vol 38 (01) ◽  
pp. 23-31 ◽  
Author(s):  
Takashi Ikeda ◽  
Tetsuya Jinno ◽  
Tadashi Masuda ◽  
Junya Aizawa ◽  
Kazunari Ninomiya ◽  
...  
Keyword(s):  
Amino Acid ◽  
Muscle Strength ◽  
Exercise Therapy ◽  
Contralateral Side ◽  
Elderly Persons ◽  
Abductor Muscle ◽  
Branched Chain Amino Acid ◽  
Significant Difference ◽  
Hip Abductor ◽  
Branched Chain

Background: Improving lower limb muscle strength is important in preventing progression of osteoarthritis (OA) and its symptoms. Exercise with branched-chain amino acid (BCAA) supplementation has been reported to affect protein anabolism in young and elderly persons. However, few studies provided daily BCAAs for patients with OA. Objective: This study examined the effects of combined BCAAs and exercise therapy on physical function improvement in women with hip OA scheduled for total hip arthroplasty. Methods: The subjects were 43 women with OA (age: 64.2[Formula: see text][Formula: see text][Formula: see text]9.4). The participants were randomly divided into two groups: BCAA ([Formula: see text]) and control ([Formula: see text]). The combined therapy was carried out for one month. Exercise intervention involved hip abductor muscle exercise in both groups. For the nutritional intervention, 6[Formula: see text]g of BCAAs or 1.2[Formula: see text]g of starch were consumed within 10[Formula: see text]min before starting the exercise. Results: There was a marginally significant difference in the main effect between the groups in 10-m timed gait time. The improvement rate in hip abductor muscle strength of the contralateral side was significantly greater in the BCAA group. Conclusion: By combining BCAA intake and exercise therapy, a significant improvement in hip abductor muscle strength of the contralateral side was achieved in women with OA.

scholarly journals Effect of Branched-Chain Amino Acid Supplementation on Recovery Following Acute Eccentric Exercise

Nutrients ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1389 ◽  
Author(s):  
Trisha VanDusseldorp ◽  
Kurt Escobar ◽  
Kelly Johnson ◽  
Matthew Stratton ◽  
Terence Moriarty ◽  
...  
Keyword(s):  
Amino Acid ◽  
Eccentric Exercise ◽  
Vertical Jump ◽  
Amino Acid Supplementation ◽  
Force Output ◽  
Maximal Voluntary Isometric Contraction ◽  
Time Points ◽  
Branched Chain Amino Acid ◽  
Significant Difference ◽  
Branched Chain

This study investigated the effect of branched-chain amino acid (BCAA) supplementation on recovery from eccentric exercise. Twenty males ingested either a BCAA supplement or placebo (PLCB) prior to and following eccentric exercise. Creatine kinase (CK), vertical jump (VJ), maximal voluntary isometric contraction (MVIC), jump squat (JS) and perceived soreness were assessed. No significant (p > 0.05) group by time interaction effects were observed for CK, soreness, MVIC, VJ, or JS. CK concentrations were elevated above baseline (p < 0.001) in both groups at 4, 24, 48 and 72 hr, while CK was lower (p = 0.02) in the BCAA group at 48 hr compared to PLCB. Soreness increased significantly from baseline (p < 0.01) in both groups at all time-points; however, BCAA supplemented individuals reported less soreness (p < 0.01) at the 48 and 72 hr time-points. MVIC force output returned to baseline levels (p > 0.05) at 24, 48 and 72 hr for BCAA individuals. No significant difference between groups (p > 0.05) was detected for VJ or JS. BCAA supplementation may mitigate muscle soreness following muscle-damaging exercise. However, when consumed with a diet consisting of ~1.2 g/kg/day protein, the attenuation of muscular performance decrements or corresponding plasma CK levels are likely negligible.

Effect of branched-chain amino acid supplements on muscle strength and muscle mass in patients with liver cirrhosis

2017 ◽  
Vol 29 (12) ◽  
pp. 1402-1407 ◽  
Author(s):  
Haruki Uojima ◽  
Seiko Sakurai ◽  
Hisashi Hidaka ◽  
Takeshi Kinbara ◽  
Ji Hyun Sung ◽  
...  
Keyword(s):  
Liver Cirrhosis ◽  
Amino Acid ◽  
Muscle Strength ◽  
Muscle Mass ◽  
Branched Chain Amino Acid ◽  
Branched Chain

scholarly journals Efficacy of branched-chain amino acid to increase muscle strength in chronic heart failure patients: an evidence-based case report

2020 ◽  
Vol 4 (1) ◽  
pp. 21
Author(s):  
Karin Wiradarma ◽  
Lily Indriani Octovia
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Amino Acid ◽  
Chronic Heart Failure ◽  
Muscle Strength ◽  
Full Text ◽  
Evidence Based ◽  
Cardiac Cachexia ◽  
Branched Chain Amino Acid ◽  
Branched Chain

Background: Chronic heart failure (CHF) patients can fall into cardiac cachexia (CC), which is marked by the decrease of muscle mass and strength. Cardiac cachexia decreases the functional capacity and quality of life also increases the length of stay, medical fees, complications, and mortality rate. Branched-chain amino acid (BCAA) accounted for 35% of amino acids that build the muscle. We hope that BCAA supplementation can increase muscle strength of CHF patients, especially the elderly who is more prone to fall into CC. Thus, we performed an evidence-based case report to seek an opportunity of BCAA supplementation to an elderly with CHF.Objectives: To determine the efficacy of BCAA supplementation on increasing muscle strength in CHF patients.Methods: Literature searching of the evidence-based case report was performed on Pubmed, Cochrane, and Scopus according to the clinical query. Screening on title, abstract, and full text was done based on eligibility criteria (meta-analysis or clinical trials, suitability to clinical questions, English language, full-text availability, and human studies), followed by duplication filter and critical appraisal.Results: A randomized-controlled trial was found, but it didn’t find a significant difference between the experimental and control groups.Conclusions: BCAA supplementation doesn’t give a significant improvement in muscle strength in CHF patients.

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