Preparation of chitosan-Epigallocatechin-3-O-gallate nanoparticles and their inhibitory effect on the growth of breast cancer cells
2018 ◽
Vol 11
(04)
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pp. 1850018
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Keyword(s):
A Cell
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In this paper, we prepared the nanoparticle drug carrier system between nanoparticles — chitosan and Epigallocatechin-3-O-gallate (EGCG) for breast cancer cell inhibiting application. For this drug carrier system, chitosan acts as a carrier and EGCG as a drug. Which were systematically characterized and thoroughly evaluated in terms of their inhibition rate and biocompatibility. We also did a cell scratch test and the result indicated that the chitosan-EGCG nanoparticles have inhibitory effect on the growth of breast cancer cells. The inhibition rate could reach up to 21.91%. This work revealed that the modification of nanoparticles paved a way for specific biomedical applications.
Keyword(s):
2008 ◽
Vol 375
(4)
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pp. 608-613
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2004 ◽
Vol 42
(12)
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pp. 695-700
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Keyword(s):
2019 ◽
Vol 08
(01)
◽
pp. 75-79
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Keyword(s):
2011 ◽
Vol 29
(27_suppl)
◽
pp. 220-220