scholarly journals Toward a Fully Resolved Fungal Tree of Life

2020 ◽  
Vol 74 (1) ◽  
pp. 291-313 ◽  
Author(s):  
Timothy Y. James ◽  
Jason E. Stajich ◽  
Chris Todd Hittinger ◽  
Antonis Rokas
Keyword(s):  
Species Delimitation ◽  
Fungal Diversity ◽  
Critical Issue ◽  
Tree Of Life ◽  
Current Status ◽  
Gene Trees ◽  
Metabolic Evolution ◽  
Genomic Technologies ◽  
Future Challenges ◽  
Fungal Tree Of Life

In this review, we discuss the current status and future challenges for fully elucidating the fungal tree of life. In the last 15 years, advances in genomic technologies have revolutionized fungal systematics, ushering the field into the phylogenomic era. This has made the unthinkable possible, namely access to the entire genetic record of all known extant taxa. We first review the current status of the fungal tree and highlight areas where additional effort will be required. We then review the analytical challenges imposed by the volume of data and discuss methods to recover the most accurate species tree given the sea of gene trees. Highly resolved and deeply sampled trees are being leveraged in novel ways to study fungal radiations, species delimitation, and metabolic evolution. Finally, we discuss the critical issue of incorporating the unnamed and uncultured dark matter taxa that represent the vast majority of fungal diversity.

scholarly journals Technologies for Water Reuse: Current Status and Future Challenges

Water ◽  
2021 ◽  
Vol 13 (6) ◽  
pp. 832
Author(s):  
Mauro Capocelli ◽  
Vincenzo Piemonte
Keyword(s):  
Sustainable Development ◽  
Water Reuse ◽  
Food Production ◽  
Current Status ◽  
The Sustainable Development ◽  
Future Challenges

Water is fundamental for the quality of both ecosystems and society, and plays a key role for energy and food production, a prerequisite for the sustainable development [...]

Nonisolated Electric Vehicle Chargers: Their Current Status and Future Challenges.

2021 ◽  
Vol 9 (2) ◽  
pp. 23-33
Author(s):  
Jin Wang ◽  
Yue Zhang ◽  
Mohamed Elshaer ◽  
William Perdikakis ◽  
Chengcheng Yao ◽  
...  
Keyword(s):  
Electric Vehicle ◽  
Current Status ◽  
Future Challenges

scholarly journals Imaging Response of Antiangiogenic and Immune-Oncology Drugs in Metastatic Renal Cell Carcinoma (mRCC): Current Status and Future Challenges

Kidney Cancer ◽  
2017 ◽  
Vol 1 (2) ◽  
pp. 107-114 ◽  
Author(s):  
Laure Fournier ◽  
Alexandre Bellucci ◽  
Yann Vano ◽  
Mehdi Bouaboula ◽  
Constance Thibault ◽  
...  
Keyword(s):  
Renal Cell Carcinoma ◽  
Cell Carcinoma ◽  
Metastatic Renal Cell Carcinoma ◽  
Renal Cell ◽  
Current Status ◽  
Future Challenges ◽  
Immune Oncology ◽  
Imaging Response

Advanced open rotor noise prediction

2014 ◽  
Vol 118 (1208) ◽  
pp. 1125-1135 ◽  
Author(s):  
M. J. Kingan
Keyword(s):  
High Speed ◽  
Broadband Noise ◽  
Current Status ◽  
Prediction Methods ◽  
Noise Prediction ◽  
Acoustic Data ◽  
Rotor Noise ◽  
Future Challenges ◽  
Open Rotor ◽  
Development And Validation

Abstract The purpose of this paper is to describe the current status of open rotor noise prediction methods and to highlight future challenges in this area. A number of analytic and numerical methods are described which can be used for predicting ‘isolated’ and ‘installed’ open rotor tonal noise. Broadband noise prediction methods are also described and it is noted that further development and validation of the current models is required. The paper concludes with a discussion of the analytical methods which are used to assess the acoustic data collected during the high-speed wind-tunnel testing of a model scale advanced open rotor rig.

scholarly journals Potential Application of Genomic Technologies in Breeding for Fungal and Oomycete Disease Resistance in Pea

Agronomy ◽  
2021 ◽  
Vol 11 (6) ◽  
pp. 1260
Author(s):  
Ambuj B. Jha ◽  
Krishna K. Gali ◽  
Zobayer Alam ◽  
V. B. Reddy Lachagari ◽  
Thomas D. Warkentin
Keyword(s):  
Disease Resistance ◽  
Genome Sequence ◽  
Potential Application ◽  
Ascochyta Blight ◽  
Gene Families ◽  
Snp Markers ◽  
Growth And Yield ◽  
Current Status ◽  
Genomic Technologies ◽  
Sequencing Platforms

Growth and yield of pea crops are severely affected by various fungal diseases, including root rot, Ascochyta blight, powdery mildew, and rust, in different parts of the world. Conventional breeding methods have led to enhancement of host plant resistance against these diseases in adapted cultivars, which is the primary option to minimize the yield losses. To support the breeding programs for marker-assisted selection, several successful attempts have been made to detect the genetic loci associated with disease resistance, based on SSR and SNP markers. In recent years, advances in next-generation sequencing platforms, and resulting improvements in high-throughput and economical genotyping methods, have been used to make rapid progress in identification of these loci. The first reference genome sequence of pea was published in 2019 and provides insights on the distribution and architecture of gene families associated with disease resistance. Furthermore, the genome sequence is a resource for anchoring genetic linkage maps, markers identified in multiple studies, identification of candidate genes, and functional genomics studies. The available pea genomic resources and the potential application of genomic technologies for development of disease-resistant cultivars with improved agronomic profile will be discussed, along with the current status of the arising improved pea germplasm.

Prevalence of Newcastle Disease Virus in Pakistan, its present status and future challenges

2021 ◽  
Vol 7 (2) ◽  
Keyword(s):  
Newcastle Disease Virus ◽  
Disease Virus ◽  
Newcastle Disease ◽  
Current Status ◽  
Poultry Products ◽  
Cost Impact ◽  
The World ◽  
Future Challenges ◽  
The Mean ◽  
Major Industry

Newcastle disease is caused by Newcastle Disease Virus (NDV) leads to severe morbidity and mortality in poultry throughout the world and considered as lentogenic, mesogenic or velogenic based on the mean death of the chicken embryo. The NDV velogenic strain is deadly endemic in Pakistan. Poultry is considered as the second major industry in Pakistan having annual growth of 8-10%. Unfortunately, the increase of NDV cases leads to severe cost impact, loss of production and livelihood. This review highlights the current status and epidemiology of NDV in Pakistan. Various genotypes and sub-genotypes have been identified in Pakistan. Various ND cases have been reported in Pakistan which has very bad consequences on the economy and dealing of poultry products.

scholarly journals Small molecules as inhibitors of PCSK9: Current status and future challenges

2019 ◽  
Vol 162 ◽  
pp. 212-233 ◽  
Author(s):  
Shengtao Xu ◽  
Shanshan Luo ◽  
Zheying Zhu ◽  
Jinyi Xu
Keyword(s):  
Small Molecules ◽  
Current Status ◽  
Future Challenges
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