scholarly journals Fully Automatic Volume Measurement of the Spleen at CT Using Deep Learning

2020 ◽  
Vol 2 (4) ◽  
pp. e190102
Author(s):  
Gabriel E. Humpire-Mamani ◽  
Joris Bukala ◽  
Ernst T. Scholten ◽  
Mathias Prokop ◽  
Bram van Ginneken ◽  
...  
Keyword(s):  
Deep Learning ◽  
Volume Measurement ◽  
Fully Automatic

scholarly journals Deep Learning Based Airway Segmentation Using Key Point Prediction

2021 ◽  
Vol 11 (8) ◽  
pp. 3501
Author(s):  
Jinyoung Park ◽  
JaeJoon Hwang ◽  
Jihye Ryu ◽  
Inhye Nam ◽  
Sol-A Kim ◽  
...  
Keyword(s):  
Deep Learning ◽  
Data Augmentation ◽  
Sagittal Plane ◽  
Automatic Segmentation ◽  
Volume Measurement ◽  
Airway Segmentation ◽  
Fully Automatic ◽  
Deep Learning Model ◽  
Regression Correlation ◽  
Learning Data

The purpose of this study was to investigate the accuracy of the airway volume measurement by a Regression Neural Network-based deep-learning model. A set of manually outlined airway data was set to build the algorithm for fully automatic segmentation of a deep learning process. Manual landmarks of the airway were determined by one examiner using a mid-sagittal plane of cone-beam computed tomography (CBCT) images of 315 patients. Clinical dataset-based training with data augmentation was conducted. Based on the annotated landmarks, the airway passage was measured and segmented. The accuracy of our model was confirmed by measuring the following between the examiner and the program: (1) a difference in volume of nasopharynx, oropharynx, and hypopharynx, and (2) the Euclidean distance. For the agreement analysis, 61 samples were extracted and compared. The correlation test showed a range of good to excellent reliability. A difference between volumes were analyzed using regression analysis. The slope of the two measurements was close to 1 and showed a linear regression correlation (r2 = 0.975, slope = 1.02, p < 0.001). These results indicate that fully automatic segmentation of the airway is possible by training via deep learning of artificial intelligence. Additionally, a high correlation between manual data and deep learning data was estimated.

A Fully Automatic Deep Learning System for L3 Slice Selection and Body Composition Assessment on Abdominal Computed Tomography. (Preprint)

2021 ◽  
Author(s):  
Jiyeon Ha ◽  
Taeyong Park ◽  
Hong-Kyu Kim ◽  
Youngbin Shin ◽  
Yousun Ko ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Deep Learning ◽  
External Validation ◽  
Abdominal Muscle ◽  
Anatomic Variations ◽  
Success Rates ◽  
Technical Success ◽  
Segmentation Accuracy ◽  
Distance Difference ◽  
Fully Automatic

BACKGROUND As sarcopenia research has been gaining emphasis, the need for quantification of abdominal muscle on computed tomography (CT) is increasing. Thus, a fully automated system to select L3 slice and segment muscle in an end-to-end manner is demanding. OBJECTIVE We aimed to develop a deep learning model (DLM) to select the L3 slice with consideration of anatomic variations and to segment cross-sectional areas (CSAs) of abdominal muscle and fat. METHODS Our DLM, named L3SEG-net, was composed of a YOLOv3-based algorithm for selecting the L3 slice and a fully convolutional network (FCN)-based algorithm for segmentation. The YOLOv3-based algorithm was developed via supervised learning using a training dataset (n=922), and the FCN-based algorithm was transferred from prior work. Our L3SEG-net was validated with internal (n=496) and external validation (n=586) datasets. L3 slice selection accuracy was evaluated by the distance difference between ground truths and DLM-derived results. Technical success for L3 slice selection was defined when the distance difference was <10 mm. Overall segmentation accuracy was evaluated by CSA error. The influence of anatomic variations on DLM performance was evaluated. RESULTS In the internal and external validation datasets, the accuracy of automatic L3 slice selection was high, with mean distance differences of 3.7±8.4 mm and 4.1±8.3 mm, respectively, and with technical success rates of 93.1% and 92.3%, respectively. However, in the subgroup analysis of anatomic variations, the L3 slice selection accuracy decreased, with distance differences of 12.4±15.4 mm and 12.1±14.6 mm, respectively, and with technical success rates of 67.2% and 67.9%, respectively. The overall segmentation accuracy of abdominal muscle areas was excellent regardless of anatomic variation, with the CSA errors of 1.38–3.10 cm2. CONCLUSIONS A fully automatic system was developed for the selection of an exact axial CT slice at the L3 vertebral level and the segmentation of abdominal muscle areas.

scholarly journals A fully automatic deep learning system for L3 slice selection and body composition assessment on abdominal computed tomography. 

2021 ◽  
Author(s):  
Jiyeon Ha ◽  
Taeyong Park ◽  
Hong-Kyu Kim ◽  
Youngbin Shin ◽  
Yousun Ko ◽  
...  
Keyword(s):  
Computed Tomography ◽  
Deep Learning ◽  
External Validation ◽  
Abdominal Muscle ◽  
Anatomic Variations ◽  
Success Rates ◽  
Technical Success ◽  
Segmentation Accuracy ◽  
Distance Difference ◽  
Fully Automatic

Abstract Background and aims: As sarcopenia research has been gaining emphasis, the need for quantification of abdominal muscle on computed tomography (CT) is increasing. Thus, a fully automated system to select L3 slice and segment muscle in an end-to-end manner is demanded. We aimed to develop a deep learning model (DLM) to select the L3 slice with consideration of anatomic variations and to segment cross-sectional areas (CSAs) of abdominal muscle and fat. Methods: Our DLM, named L3SEG-net, was composed of a YOLOv3-based algorithm for selecting the L3 slice and a fully convolutional network (FCN)-based algorithm for segmentation. The YOLOv3-based algorithm was developed via supervised learning using a training dataset (n=922), and the FCN-based algorithm was transferred from prior work. Our L3SEG-net was validated with internal (n=496) and external validation (n=586) datasets. L3 slice selection accuracy was evaluated by the distance difference between ground truths and DLM-derived results. Technical success for L3 slice selection was defined when the distance difference was <10 mm. Overall segmentation accuracy was evaluated by CSA error. The influence of anatomic variations on DLM performance was evaluated.Results: In the internal and external validation datasets, the accuracy of automatic L3 slice selection was high, with mean distance differences of 3.7±8.4 mm and 4.1±8.3 mm, respectively, and with technical success rates of 93.1% and 92.3%, respectively. However, in the subgroup analysis of anatomic variations, the L3 slice selection accuracy decreased, with distance differences of 12.4±15.4 mm and 12.1±14.6 mm, respectively, and with technical success rates of 67.2% and 67.9%, respectively. The overall segmentation accuracy of abdominal muscle areas was excellent regardless of anatomic variation, with the CSA errors of 1.38–3.10 cm2.Conclusions: A fully automatic system was developed for the selection of an exact axial CT slice at the L3 vertebral level and the segmentation of abdominal muscle areas.

scholarly journals DeepRes: a new deep-learning- and aspect-based local resolution method for electron-microscopy maps

IUCrJ ◽  
2019 ◽  
Vol 6 (6) ◽  
pp. 1054-1063 ◽  
Author(s):  
Erney Ramírez-Aportela ◽  
Javier Mota ◽  
Pablo Conesa ◽  
Jose Maria Carazo ◽  
Carlos Oscar S. Sorzano
Keyword(s):  
Electron Microscopy ◽  
Deep Learning ◽  
Feature Detection ◽  
Quality Measure ◽  
Human Observer ◽  
Resolution Method ◽  
Model Based ◽  
Local Quality ◽  
Fully Automatic

In this article, a method is presented to estimate a new local quality measure for 3D cryoEM maps that adopts the form of a `local resolution' type of information. The algorithm (DeepRes) is based on deep-learning 3D feature detection. DeepRes is fully automatic and parameter-free, and avoids the issues of most current methods, such as their insensitivity to enhancements owing to B-factor sharpening (unless the 3D mask is changed), among others, which is an issue that has been virtually neglected in the cryoEM field until now. In this way, DeepRes can be applied to any map, detecting subtle changes in local quality after applying enhancement processes such as isotropic filters or substantially more complex procedures, such as model-based local sharpening, non-model-based methods or denoising, that may be very difficult to follow using current methods. It performs as a human observer expects. The comparison with traditional local resolution indicators is also addressed.

scholarly journals High interstudy repeatability of automatic deep learnt biventricular CMR measurements

2021 ◽  
Vol 22 (Supplement_2) ◽  
Author(s):  
S Alabed ◽  
K Karunasaagarar ◽  
F Alandejani ◽  
P Garg ◽  
J Uthoff ◽  
...  
Keyword(s):  
Pulmonary Hypertension ◽  
Deep Learning ◽  
Automatic Segmentation ◽  
Intraclass Correlation ◽  
Therapy Response ◽  
Left Ventricular ◽  
Dice Similarity Coefficient ◽  
Learning Approaches ◽  
Fully Automatic ◽  
Automatic Contouring

Abstract Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): Wellcome Trust (UK), NIHR (UK) Introduction Cardiac magnetic resonance (CMR) measurements have significant diagnostic and prognostic value. Accurate and repeatable measurements are essential to assess disease severity, evaluate therapy response and monitor disease progression. Deep learning approaches have shown promise for automatic left ventricular (LV) segmentation on CMR, however fully automatic right ventricular (RV) segmentation remains challenging. We aimed to develop a biventricular automatic contouring model and evaluate the interstudy repeatability of the model in a prospectively recruited cohort. Methods A deep learning CMR contouring model was developed in a retrospective multi-vendor (Siemens and General Electric), multi-pathology cohort of patients, predominantly with heart failure, pulmonary hypertension and lung diseases (n = 400, ASPIRE registry). Biventricular segmentations were made on all CMR studies across cardiac phases. To test the accuracy of the automatic segmentation, 30 ASPIRE CMRs were segmented independently by two CMR experts. Each segmentation was compared to the automatic contouring with agreement assessed using the Dice similarity coefficient (DSC).  A prospective validation cohort of 46 subjects (10 healthy volunteers and 36 patients with pulmonary hypertension) were recruited to assess interstudy agreement of automatic and manual CMR assessments. Two CMR studies were performed during separate sessions on the same day. Interstudy repeatability was assessed using intraclass correlation coefficient (ICC) and Bland-Altman plots.  Results DSC showed high agreement (figure 1) comparing automatic and expert CMR readers, with minimal bias towards either CMR expert. The scan-scan repeatability CMR measurements were higher for all automatic RV measurements (ICC 0.89 to 0.98) compared to manual RV measurements (0.78 to 0.98). LV automatic and manual measurements were similarly repeatable (figure 2). Bland-Altman plots showed strong agreement with small mean differences between the scan-scan measurements (figure 2). Conclusion Fully automatic biventricular short-axis segmentations are comparable with expert manual segmentations, and have shown excellent interstudy repeatability.

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