scholarly journals Comparative Benefit-to–Radiation Risk Ratio of Molecular Breast Imaging, Two-Dimensional Full-Field Digital Mammography with and without Tomosynthesis, and Synthetic Mammography with Tomosynthesis

2019 ◽  
Vol 1 (1) ◽  
pp. e190005 ◽  
Author(s):  
Matthew Brown ◽  
Matthew F. Covington
2019 ◽  
Vol 12 (10) ◽  
pp. e230043
Author(s):  
Jeremy SL Ong ◽  
Felicity Whitewood ◽  
Donna B Taylor ◽  
Deepthi Dissanayake

Molecular breast imaging (MBI) is a relatively new technique with high sensitivity for breast cancer detection. However, because it only provides limited anatomical information, cross-correlation of MBI findings with conventional breast imaging modalities such as full field digital mammography can be challenging. We report a case of a positive MBI study in a supplemental screening setting, where cross-correlation of MBI, ultrasound, mammogram and biopsy findings was difficult. Contrast-enhanced spectral mammography (CESM) demonstrated a hypervascular lesion at the biopsy clip, helping to prove imaging/histopathological concordance. This case highlights the challenges of incorporating MBI into conventional imaging workup, as well as the use of CESM in problem solving.


Author(s):  
Sushil J. Sikchi

Evolution in breast imaging has dramatically changed and upgraded  by  wide variety of technologic advances from the early days of direct-exposure film mammography to xeromammography to screen-film mammography to the current era of full-field digital mammography and digital breast tomosynthesis. In early 1950 Mammography has been introduced along with the breast self examination. After two decades thermography and ultrasound examination  has been added in the breast imaging . From year 1990 to 2000 drastic technological advances, organized screening,  with  BI-RAD  classification introduced by  American College of Radiology Breast Imaging Reporting and Data System have helped to shape the specialty of breast imaging. With the development of digital mammography and tomosynthesis in 2020, breast ultrasonography and breast magnetic resonance imaging, both complementary to mammography,  has set new standard in diagnostic accuracy of breast  lesions.This  paper gives a quick insight  to the development of   breast imaging and reviews the evolution of breast imaging starting from a historical perspective and progressing to the present day. Keywords: Mammography screening, tomosynthesis ,Digital mammography.


2010 ◽  
Vol 61 (3) ◽  
pp. 162-169 ◽  
Author(s):  
Anabel M. Scaranelo ◽  
Pavel Crystal ◽  
Karina Bukhanov ◽  
Thomas H. Helbich

Purpose The purpose of this study was to evaluate the sensitivity of a direct computer-aided detection (CAD) system (d-CAD) in full-field digital mammography (FFDM) for the detection of microcalcifications not associated with mass or architectural distortion. Materials and Methods A database search of 1063 consecutive stereotactic core biopsies performed between 2002 and 2005 identified 196 patients with Breast Imaging-Reporting and Data System (BI-RADS) 4 and 5 microcalcifications not associated with mass or distortion detected exclusively by bilateral FFDM. A commercially available CAD system (Second Look, version 7.2) was retrospectively applied to the craniocaudal and mediolateral oblique views in these patients (mean age, 59 years; range, 35–84 years). Breast density, location and mammographic size of the lesion, distribution, and tumour histology were recorded and analysed by using χ2, Fisher exact, or McNemar tests, when applicable. Results When using d-CAD, 71 of 74 malignant microcalcification cases (96%) and 101 of 122 benign microcalcifications (83%) were identified. There was a significant difference ( P < .05) between CAD sensitivity on the craniocaudal view, 91% (68 of 75), vs CAD sensitivity on the mediolateral oblique view, 80% (60 of 75). The d-CAD sensitivity for dense breast tissue (American College of Radiology [ACR] density 3 and 4) was higher (97%) than d-CAD sensitivity (95%) for nondense tissue (ACR density 1 and 2), but the difference was not statically significant. All 28 malignant calcifications larger than 10 mm were detected by CAD, whereas the sensitivity for lesions small than or equal to 10 mm was 94%. Conclusions D-CAD had a high sensitivity in the depiction of asymptomatic breast cancers, which were seen as microcalcifications on FFDM screening, with a sensitivity of d-CAD on the craniocaudal view being significantly better. All malignant microcalcifications larger than 10 mm were detected by d-CAD.


Author(s):  
Pradipta C. Hande ◽  
Sabita S. Desai ◽  
Sarabjeet K. Arneja ◽  
Sreedevi Sathian

Abstract Background Mammography has been established as the key modality in the detection and diagnosis of breast cancers. Digital breast tomosynthesis (DBT) has emerged as a mammographic technique which allows improved visualization of abnormalities by reducing the effect of overlapping breast tissue. Purpose This article is a pictorial essay which highlights the advantages of DBT with two-dimensional (2D) synthesized mammography (2DSM) images, its clinical applications, and its role in breast imaging. Materials and Methods Selenia Dimensions HD mammography machine performs DBT which acquires a series of low-dose digital mammographic images of the compressed breast followed by full-field digital mammography. Software using specialized algorithms helps to create a 2DSM image reconstructed from the DBT data set. The images are interpreted on a dedicated work station on high-resolution monitors by the radiologist. American College of Radiology Breast Imaging-Reporting and Data System (BI-RADS) lexicon is used for reporting. High-resolution breast ultrasound which includes evaluation of the axilla is done for all cases. Conclusion DBT improves detection and better characterization of lesions which thereby increases confidence of interpretation of mammograms and assigning BI-RADS categories for further management.


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