Effect of prolonged bed rest on renal diluting capacity in normal man.

AbstractTo explore the effectiveness of microgravity simulated by head-down bed rest (HDBR) and artificial gravity (AG) with exercise on lung function. Twenty-four volunteers were randomly divided into control and exercise countermeasure (CM) groups for 96 h of 6° HDBR. Comparisons of pulse rate, pulse oxygen saturation (SpO2) and lung function were made between these two groups at 0, 24, 48, 72, 96 h. Compared with the sitting position, inspiratory capacity and respiratory reserve volume were significantly higher than before HDBR (0° position) (P< 0.05). Vital capacity, expiratory reserve volume, forced vital capacity, forced expiratory volume in 1 s, forced inspiratory vital capacity, forced inspiratory volume in 1 s, forced expiratory flow at 25, 50 and 75%, maximal mid-expiratory flow and peak expiratory flow were all significantly lower than those before HDBR (P< 0.05). Neither control nor CM groups showed significant differences in the pulse rate, SpO2, pulmonary volume and pulmonary ventilation function over the HDBR observation time. Postural changes can lead to variation in lung volume and ventilation function, but a HDBR model induced no changes in pulmonary function and therefore should not be used to study AG CMs.

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Bed Rest for Hypertension in Pregnancy: Evidence is Weak

Family Practice News ◽

10.1016/s0300-7073(06)72535-x ◽

2006 ◽

Vol 36 (2) ◽

pp. 50

Author(s):

ROBERT FINN

Keyword(s):

Bed Rest ◽

Hypertension In Pregnancy ◽

In Pregnancy

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Observations on Cardiac Output and ”Pulmonary Blood Volume” in Normal Man by External Recording of the Intracardiac Flow of 131I Labelled Albumin

Nuklearmedizin ◽

10.1055/s-0037-1621159 ◽

1961 ◽

Vol 1 (04) ◽

pp. 353-379

Author(s):

Jacques Lammerant ◽

Norman Veall ◽

Michel De Visscher

Keyword(s):

Cardiac Output ◽

Blood Volume ◽

Normal Subjects ◽

Published Data ◽

Total Blood Volume ◽

Total Blood ◽

Pulmonary Blood Volume ◽

Intracardiac Flow ◽

Normal Man ◽

Mean Circulation

Summary1. The technique for the measurement of cardiac output by external recording of the intracardiac flow of 131I labelled human serum albumin has been extended to provide a measure of the mean circulation time from right to left heart and hence a new approach to the estimation of the pulmonary blood volume.2. Values for the basal cardiac output in normal subjects and its variations with age are in good agreement with the previously published data of other workers.3. The pulmonary blood volume in normal man in the basal state was found to be 28.2 ± 0.6% of the total blood volume.4. There was no correlation between cardiac output and pulmonary blood volume in a series of normal subjects in the basal state.5. The increase in cardiac output during digestion was associated with a decrease in pulmonary blood volume equal to 6.3 ± 1.2% of the total blood volume, that is, about 280 ml.6. The increase in cardiac output during exercise was associated with a decrease in pulmonary blood volume equal to 4.5 ± 1.0% of the total blood volume, that is, about 200 ml.7. The increase in cardiac output attributed to alarm is not associated with a decrease in pulmonary blood volume, the latter may in fact be increased.8. The total blood volume is advocated as a standard of reference for studies of this type in normal subjects in preference to body weight or surface area.9. The significance of these results and the validity of the method are discussed.

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Delayed interval delivery of the second and third fetuses in multiple pregnancy triplet (Сase report)

HEALTH OF WOMAN ◽

10.15574/hw.2016.111.148 ◽

2016 ◽

pp. 148-152

Author(s):

Y. Dubossarskaya ◽

◽

L. Padalko ◽

L. Zakharchenko ◽

E. Savel’eva ◽

...

Keyword(s):

Preterm Delivery ◽

Multiple Pregnancy ◽

Bed Rest ◽

Perinatal Morbidity ◽

Perinatal Complications ◽

Triplet Pregnancy ◽

Satisfactory Condition ◽

Nulliparous Women ◽

Perinatal Center ◽

Delayed Interval Delivery

This article describes a clinical case of vaginal delivery in nulliparous women 24 years old delayed interval delivery of the second and third fetuses in spontaneous multiple pregnancy dichorionic triamniotic triplet in a tertiary perinatal center. After preterm delivery in 27+5 weeks of gestation the first fetus to reduce perinatal morbidity and mortality of two fetuses that are left in the uterus, with informed consent of the woman preterm delivery the second and third fetuses occurred at intervals of 38 days, in 33+1 weeks of gestation. Careful monitoring of the state of the mother and fetuses was conducted. To increase the interval between the birth of the first fetus and the second and the third fetuses, prevention of obstetric and perinatal complications used tocolysis, antibiotics, progesterone, the prevention of respiratory distress syndrome of the newborn by corticosteroids and bed rest. Three girls were born alive with a weight of 980, 1800 and 1950 grams correspondingly. Childbirth complicated second degree perineal laceration and retained portions of placenta and membranes, puerperal period was uneventful. After 1.5 months, all infants discharged with her mother in a satisfactory condition with a weight of more than 3000 grams. Key words: multiple pregnancy, triplet pregnancy, delayed interval delivery in triplet pregnancy, preterm delivery.

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