scholarly journals Collagenous Gastritis

1989 ◽  
Vol 3 (5) ◽  
pp. 171-174 ◽  
Author(s):  
Hugh J. Freeman ◽  
James R.A. Piercy ◽  
Robert J. Raine
Keyword(s):  
Weight Loss ◽  
Gastric Emptying ◽  
Gastric Mucosa ◽  
Parenteral Nutrition ◽  
Inflammatory Process ◽  
Collagenous Colitis ◽  
Immune Mediated ◽  
Chronic Disorder ◽  
Collagenous Gastritis

A 54-year-old woman presented with nausea, vomiting and weight loss associated with impaired gastric emptying necessitating institution of parenteral nutrition. Subsequent studies revealed an unusual gastric mucosa! inflammatory process characterized by unique subepithelial collagenous deposits. Collagenous gastritis appears to be a distinct, possibly immune-mediated, chronic disorder, pathologically reminiscent of collagenous sprue and collagenous colitis.

Collagenous Gastritis: An Unusual Association With Profound Weight Loss

2004 ◽  
Vol 128 (2) ◽  
pp. 229-232 ◽  
Author(s):  
Hanlin L. Wang ◽  
Amit G. Shah ◽  
Lisa M. Yerian ◽  
Russell D. Cohen ◽  
John Hart
Keyword(s):  
Weight Loss ◽  
Gastric Mucosa ◽  
Unusual Case ◽  
Clinicopathologic Features ◽  
Unusual Association ◽  
Collagen Layer ◽  
Collagenous Gastritis

Abstract Collagenous gastritis is a distinctive disorder characterized by thickening of the subepithelial collagen layer in the gastric mucosa. Although this entity was recognized in 1989, its etiology, pathogenesis, and clinicopathologic features remain poorly understood because of its rarity. An unusual case of collagenous gastritis was observed in a 37-year-old man who presented with profound weight loss, a feature that has not previously been emphasized.

scholarly journals Collagenous Gastritis: An Unusual Presentation With Tubular Shaped Stomach

2020 ◽  
Vol 8 ◽  
pp. 232470962094469
Author(s):  
Nathaly Cortez ◽  
Manuel Berzosa ◽  
Adam Jacobs ◽  
Michael Bloom
Keyword(s):  
Weight Loss ◽  
Gastric Mucosa ◽  
Clinical Presentation ◽  
Case Reports ◽  
Collagen Deposition ◽  
Unique Case ◽  
Mucosal Atrophy ◽  
Endoscopic Findings ◽  
History Of ◽  
Collagenous Gastritis

Collagenous gastritis is a rare histopathologic entity that causes marked subepithelial collagen deposition in the gastric mucosa. Clinical presentation is diverse, considering only less than 100 cases have been reported. However, we report a unique case of isolated collagenous gastritis in a 71-year-old female who presented with a 6-month history of dyspepsia and 27 kg weight loss. Her endoscopic findings revealed a tubular shaped stomach with diffuse gastric mucosal atrophy, findings that differ with previous case reports of a cobblestone pattern. Treatment remains unclear.

scholarly journals Topographic Mapping of Collagenous Gastritis

2001 ◽  
Vol 15 (7) ◽  
pp. 475-478 ◽  
Author(s):  
Hugh J Freeman
Keyword(s):  
Abdominal Pain ◽  
Inflammatory Process ◽  
Collagenous Colitis ◽  
Gastric Body ◽  
Topographic Mapping ◽  
Multiple Site ◽  
Collagenous Gastritis ◽  
Topographic Distribution

A 74-year-old woman was investigated for abdominal pain and diarrhea. Endoscopic examinations including biopsies of the stomach and colon demonstrated the typical subepithelial deposits characteristic of collagenous gastritis and collagenous colitis. Histochemical and ultrastructural methods confirmed the presence of collagen in the subepithelial deposits. The topographic distribution of these collagen deposits and their relationship to the inflammatory process in the stomach were then defined by endoscopic mapping and multiple site biopsies of the mucosa in the gastric body and antrum. These studies indicate that collagenous gastritis not only is distinctive, but also is a far more extensive and diffuse inflammatory process than has previously been appreciated.

Effect of a cross-linked cellulose-containing weight-loss supplement on gastric emptying and sensory functions in obese subjects

2008 ◽  
Vol 3 (S 1) ◽  
Author(s):  
HK Berthold ◽  
S Unverdorben ◽  
R Degenhardt ◽  
B Geypens ◽  
I Gouni-Berthold
Keyword(s):  
Weight Loss ◽  
Gastric Emptying ◽  
Obese Subjects ◽  
Sensory Functions

scholarly journals Incidence and Outcomes of Home Parenteral Nutrition in Patients With Crohn Disease in Olmsted County, Minnesota

2020 ◽  
Vol 2 (4) ◽  
Author(s):  
Zeinab Bakhshi ◽  
Siddhant Yadav ◽  
Bradley R Salonen ◽  
Sara L Bonnes ◽  
Jithinraj Edakkanambeth Varayil ◽  
...  
Keyword(s):  
Weight Loss ◽  
Parenteral Nutrition ◽  
Short Bowel Syndrome ◽  
Crohn Disease ◽  
Severe Disease ◽  
Bloodstream Infections ◽  
Home Parenteral Nutrition ◽  
Average Weight ◽  
Olmsted County ◽  
Short Bowel

Abstract Background We sought to estimate the incidence of home parenteral nutrition (HPN) use in a population-based cohort of patients with Crohn disease (CD), and to assess clinical outcomes and complications associated with HPN. Methods We used the Rochester Epidemiology Project (REP) to identify residents of Olmsted County, who were diagnosed with CD between 1970 and 2011, and required HPN. Results Fourteen out of 429 patients (3.3%) with CD received HPN (86% female). Eleven patients (79%) had moderate–severe CD and 12 patients (86%) had fistulizing disease. Thirteen patients (93%) underwent surgery, primarily due to obstruction. Among CD incidence cases, the cumulative incidence of HPN from the date of CD diagnosis was 0% at 1 year, 0.5% at 5 years, 0.8% at 10 years, and 2.4% at 20 years. Indications for HPN included short bowel syndrome in 64%, malnutrition in 29%, and bowel rest in 21%. The median duration of HPN was 2.5 years. There was an average weight gain of 1.2 kg at 6 months, an average weight loss of 1.4 kg at 1 year, and a further weight loss of 2.2 kg at 2 years from the start of HPN. Patients were hospitalized a mean of 5 times after the start of HPN, mainly due to catheter-related bloodstream infections and thrombosis. Conclusions Less than 4% of patients with CD need HPN. Most have moderate to severe disease with short bowel syndrome or malnutrition. Possible reasons for the patients’ weight loss could be noncompliance, and increased metabolic needs because of active disease.

scholarly journals Efficacy of a Peruvian Botanical Remedy (Sabell A4+) for Treating Liver Disease and Protecting Gastric Mucosal Integrity

2019 ◽  
Vol 2019 ◽  
pp. 1-11
Author(s):  
Mark G. Swain ◽  
John L. Wallace ◽  
D. Lorne Tyrrell ◽  
José Cabanillas ◽  
Steven K. H. Aung ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Liver Disease ◽  
Hepatitis C ◽  
Gastric Mucosa ◽  
Virus Replication ◽  
Positive Interactions ◽  
Mucosal Integrity ◽  
Immune Mediated ◽  
Anti Inflammatory

The purpose of this study was to determine the efficacy of a Peruvian botanical formulation for treating disorders of hepatic function and gastric mucosal integrity. The formulation A4+ (Sabell Corporation) contains extracts of Curcuma longa rhizome, Cordia lutea flower, and Annona muricata leaf. Individually these plants have been used as traditional remedies for liver disease. We report the efficacy of A4+ and its components using a variety of in vitro and in vivo disease models. The methods used included tests for antioxidant, anti-inflammatory, and antiviral activity as well as mouse models of liver disease, including Concanavalin A-induced immune-mediated hepatitis and a bile duct ligation model for evaluating sickness behaviour associated with liver disease. Rat models were used to evaluate the gastric mucosal protective property of A4+ following indomethacin challenge and to evaluate its anti-inflammatory action in an “air pouch” model. In all tests, A4+ proved to be more effective than placebo. A4+ was antioxidant and anti-inflammatory and diminished Hepatitis C virus replication in vitro. In animal models, A4+ was shown to protect the liver from immune-mediated hepatitis, improve behavioural function in animals with late stage liver disease, and protect the rat gastric mucosa from ulceration following NSAID exposure. We conclude that A4+ ameliorated many aspects of liver injury, inhibited hepatitis C virus replication, and protected the gastric mucosa from NSAIDs. These varied beneficial properties appear to result from positive interactions between the three constituent herbs.

Lupus mastitis

2021 ◽  
Author(s):  
N. WILLERS ◽  
P. BERTELOOT ◽  
I. WITTEVRONGHEL ◽  
G. JACOMEN ◽  
V. SCHELFHOUT ◽  
...  
Keyword(s):  
Lupus Erythematosus ◽  
Inflammatory Process ◽  
Breast Lesion ◽  
Cell Lymphoma ◽  
Subcutaneous Fat ◽  
Fat Tissue ◽  
Lupus Panniculitis ◽  
Immune Mediated ◽  
History Of ◽  
Subcutaneous Fat Tissue

Lupus mastitis Systemic lupus erythematosus (SLE) infrequently presents itself as lupus panniculitis. In lupus panniculitis the subcutaneous fat tissue is involved in the inflammatory process. Lupus mastitis is again a rare variant of lupus panniculitis, probably caused by an immune-mediated inflammatory process. In literature on the topic we can find 30 cases of lupus mastitis in men and women. Lupus mastitis may present like a breast lesion suspected to be malignant, clinically and radiologically. In the differential diagnosis we consider inflammatory breast cancer, subcutaneous panniculitis-like T-cell lymphoma (SPTL) and diabetes mastopathy. With a medical history of SLE and signs of inflammation of the skin above the lesion however, a diagnosis of lupus mastopathy is more presumable. Medical treatment seems more indicated in lupus mastitis, because delayed healing after surgical procedures is often reported. Even though methylprednisolone and chloroquine give clinical improvement, they need to be repeated often because of a high risk of relapse.

scholarly journals An Unusual Case of Collagenous Gastritis: Incidental Finding in a Patient Presenting with Dysphagia

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Chiu-Hsiang Liao ◽  
Maruf Saddik ◽  
Stephen Ip
Keyword(s):  
Gastric Mucosa ◽  
Young Woman ◽  
Unusual Case ◽  
Incidental Finding ◽  
Case Reports ◽  
Collagen Deposition ◽  
Inflammatory Infiltrates ◽  
Collagenous Gastritis

Collagenous gastritis is a condition characterized by subepithelial deposition of collagen in the gastric mucosa. This condition is rare, with less than 100 cases reported in the literature. Patients with collagenous gastritis typically present with pain or diarrhea. Here, we present a case of a young woman with dysphagia who was found to have esophageal webs and an incidental finding of diffuse gastritis with a cobblestone appearance of the mucosa on endoscopy. Subsequent histology demonstrated features of collagenous gastritis, including mucosal inflammatory infiltrates and collagen deposition. This is one of the few case reports of incidental collagenous gastritis and highlights the importance of judicious use of biopsies.

Surgical correction of severe dorsal tracheal membrane redundancy in a Belgian shepherd dog

2018 ◽  
Vol 6 (3) ◽  
pp. e000644
Author(s):  
Vlad Focsaneanu ◽  
Pieter Nelissen ◽  
Simon Tappin
Keyword(s):  
Weight Loss ◽  
Treatment Option ◽  
Chronic Cough ◽  
Exercise Tolerance ◽  
Symptomatic Treatment ◽  
Surgical Correction ◽  
Exercise Intolerance ◽  
Tracheal Lumen ◽  
Inspiratory Stridor ◽  
Immune Mediated

A two-year-old working Belgian shepherd dog was referred for diagnosis and management of a chronic cough, exercise intolerance and inspiratory stridor. A diagnosis of severe dorsal tracheal membrane redundancy was made based on radiography and tracheoscopy. Vomiting, weight loss and lethargy were also reported at initial presentation presumed secondary to dietary indiscretion, which was supported by the identification of undigested bones in the stomach on radiographs and ultrasound; these signs resolved with symptomatic treatment. The patient had previously been diagnosed with primary immune-mediated polyarthritis and had responded well to immunomodulatory medication. To correct the narrowing of the tracheal lumen, the dorsal tracheal membrane was plicated surgically, improving the tracheal diameter postoperatively. Twelve weeks later the dog had returned to full exercise, and the handler reported excellent exercise tolerance and no cough. Plication of excessive dorsal tracheal membrane is one possible treatment option for dogs with severe dorsal tracheal membrane redundancy.

A Single-Center, Randomized, Placebo-Controlled, 16-Week Trial of Effects of Liraglutide on Weight Loss and Relationship to Change in Gastric Emptying in Obese Patients

2017 ◽  
Vol 152 (5) ◽  
pp. S634-S635
Author(s):  
Hoda C. Kadouh ◽  
Matthew Clark ◽  
Sarah A. Kalsy ◽  
Karen M. Graszer ◽  
Karen Grothe ◽  
...  
Keyword(s):  
Weight Loss ◽  
Gastric Emptying ◽  
Obese Patients ◽  
Single Center
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