scholarly journals Laparoscopic Nephroureterectomy: Oncologic Outcomes and Management of Distal Ureter; Review of the Literature

2009 ◽  
Vol 2009 ◽  
pp. 1-4 ◽  
Author(s):  
Andre Berger ◽  
Amr Fergany
Keyword(s):  
Open Surgery ◽  
Transitional Cell ◽  
Oncologic Outcomes ◽  
Perioperative Outcomes ◽  
Review Of The Literature ◽  
Distal Ureter ◽  
Upper Tract ◽  
Current Context

Introduction. Laparoscopic radical nephroureterectomy (LNU) is being increasingly performed at several centers across the world. We review oncologic outcomes after LNU procedure and the techniques for the management of distal ureter.Materials and Methods. A comprehensive review of the literature was performed on the oncological outcomes and management of distal ureter associated with LNU for upper tract transitional cell carcinoma (TCC).Results and Discussion. LNU for upper tract TCC is performed pure laparoscopically (LNU) or hand-assisted (HALNU). The management of the distal ureter is still debated. LNU appears to have superior perioperative outcomes when compared to open surgery. Intermediate term oncologic outcomes after LNU are comparable to open nephroureterectomy (ONU).Conclusions. Excision of the distal ureter and bladder cuff during nephroureterectomy remains controversial. Intermediate term oncologic outcomes for LNU compare well with ONU. Initial long-term oncologic outcomes are encouraging. Prospective randomized comparison between LNU and open surgery is needed to define the role of these modalities in the current context.

1763: Stage Migration of upper Tract Transitional Cell Carcinoma: An Argument for the Continued Role of Endourologic Diagnosis and Treatment

2004 ◽  
Vol 171 (4S) ◽  
pp. 466-466
Author(s):  
Stephen A. Boorjian ◽  
Casey K. Ng ◽  
Ravi Munver ◽  
R. Ernest Sosa ◽  
E. Darracott Vaughan ◽  
...  
Keyword(s):  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Diagnosis And Treatment ◽  
Stage Migration ◽  
Upper Tract

Is there a rendezvous for SARS-CoV-2 and Agmatine?

Coronaviruses ◽  
2022 ◽  
Vol 03 ◽  
Author(s):  
Nandkishor Kotagale ◽  
Brijesh Taksande ◽  
Nazma Inamdar
Keyword(s):  
Neuromuscular Diseases ◽  
Neurological Complications ◽  
Nervous System Diseases ◽  
Review Of The Literature ◽  
Long Term Effects ◽  
Peripheral Nervous System Diseases ◽  
Neurological Effects ◽  
Specific Symptoms

Abstract: The catastrophe of the ongoing COVID-19 pandemic is caused by Severe Acute Respiratory Syndrome Corona Virus-2 (SARS-CoV-2). The respiratory system appears to be ground zero in the majority of the patients. However, many other organs can get infected by cytokines, chemokines and other mediators released in response to the presence of the virus. The neurotropism by the SARS-CoV-2 is established beyond doubt. In addition to non-specific symptoms, the symptoms specific to central and/or peripheral nervous system diseases as well as neuromuscular diseases have been observed in numerous clinical cases. These observations and the experiences with other coronavirus infections earlier and flu pandemics raise concerns not only about the neurological effects in active disease but also about the long-term effects generated by the infection, immune and inflammatory functions. The knowledge of biological actions of agmatine in the backdrop of physiological events instigated by invading SARS-CoV-2 and host’s response, especially in neural events, focuses on the possible overlaps of biomolecular pathways at a number of instances. This is not surprising since the factors stimulated during SARS-CoV-2 infection are the disease-generating neuroinflammatory components altered by agmatine. Hence, we hypothesize the possible beneficial role of agmatine in SARS-CoV-2 infection. Based on a narrative review of the literature, agmatine can be proposed as a plausible beneficial candidate for supporting treatment of SARS-CoV-2 infection and for addressing post-infection neurological complications.

scholarly journals Possible Relationship between Long-Term Adverse Health Effects of Gonad-Removing Surgical Sterilization and Luteinizing Hormone in Dogs

Animals ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 599
Author(s):  
Michelle A. Kutzler
Keyword(s):  
Luteinizing Hormone ◽  
Cruciate Ligament ◽  
Transitional Cell ◽  
Reproductive Function ◽  
Receptor Activation ◽  
Main Role ◽  
Nitric Oxide Release ◽  
Neoplastic Tissues

Spaying and neutering dogs is commonly used to prevent the birth of unwanted animals and eliminate the risk of reproductive diseases. However, removal of the gonads prevents the feedback of estrogen and testosterone on the pituitary and hypothalamus. As a result, luteinizing hormone (LH) is continuously elevated at supraphysiologic concentrations. Although the main role of LH is for reproductive function (e.g., ovulation), there are LH receptors present in several normal tissues including the thyroid and adrenal glands, gastrointestinal tract, cranial cruciate ligament and round ligament, and lymphocytes. In addition, there are LH receptors present in several neoplastic tissues (e.g., lymphoma, hemangiosarcoma, mastocytoma, transitional cell carcinoma, and osteosarcoma). The role of LH receptors in non-reproductive normal and neoplastic tissues is not known but may stimulate nitric oxide release and induce cell division. The precise etiology of the increased incidence of several non-reproductive long-term health complications following spaying and neutering is not known but may be related to LH receptor activation in these non-reproductive target tissues. How these effects may be mediated is described in this review.

Oncologic Outcomes for Complete Robot-Assisted Laparoscopic Management of Upper-Tract Transitional Cell Carcinoma

2010 ◽  
Vol 24 (6) ◽  
pp. 969-975 ◽  
Author(s):  
Jonathan A. Eandi ◽  
Rebecca A. Nelson ◽  
Timothy G. Wilson ◽  
David Y. Josephson
Keyword(s):  
Transitional Cell Carcinoma ◽  
Cell Carcinoma ◽  
Transitional Cell ◽  
Oncologic Outcomes ◽  
Robot Assisted ◽  
Laparoscopic Management ◽  
Upper Tract

scholarly journals Erratum to: The role of radiotherapy in adult medulloblastoma: long-term single-institution experience and a review of the literature

2011 ◽  
Vol 106 (2) ◽  
pp. 325-325
Author(s):  
M. Balducci ◽  
S. Chiesa ◽  
D. Chieffo ◽  
S. Manfrida ◽  
N. Dinapoli ◽  
...  
Keyword(s):  
Review Of The Literature ◽  
Single Institution ◽  
Adult Medulloblastoma

Long-Term Outcome of Hand-Assisted Laparoscopic Radical Nephroureterectomy for Upper-Tract Urothelial Carcinoma: Comparison with Open Surgery

2007 ◽  
Vol 21 (6) ◽  
pp. 595-599 ◽  
Author(s):  
Shiu-Dong Chung ◽  
Shih-Chieh Chueh ◽  
Ming-Kuen Lai ◽  
Chao-Yuan Huang ◽  
Yeong-Shiau Pu ◽  
...  
Keyword(s):  
Urothelial Carcinoma ◽  
Open Surgery ◽  
Upper Tract Urothelial Carcinoma ◽  
Radical Nephroureterectomy ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Upper Tract

Update on the Diagnosis and Management of Popliteal Aneurysm and Literature Review

Vascular ◽  
2006 ◽  
Vol 14 (2) ◽  
pp. 103-108 ◽  
Author(s):  
Albeir Y. Mousa ◽  
Robert B. Beauford ◽  
Peter Henderson ◽  
Prem Patel ◽  
Peter L. Faries ◽  
...  
Keyword(s):  
Gold Standard ◽  
Open Surgery ◽  
Clinical Presentation ◽  
Survival Outcomes ◽  
Significant Morbidity ◽  
Endovascular Stents ◽  
Popliteal Aneurysm ◽  
Indications For Use

Popliteal artery aneurysms (PAAs) are the most frequent peripheral aneurysm with a significant morbidity if left untreated. Open surgical technique is still considered the gold standard; however the revolution in endovascular repair has proven to be a valid alternative option in selected patients. The role of endovascular treatment in PAA is still considered in its infancy. In addition, the indications for use of endovascular stents as compared to standard open surgery have not yet been fully defined and more studies are warranted to characterize the durability of this technique. This article describes the general principles of the natural history, clinical presentation, and long-term limb salvage and survival outcomes for patients with such aneurysms. It also details the features and results for the devices in current use and highlights the current consensus in the management of PAA.

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