scholarly journals Cutaneous Horn-Related Kaposi's Sarcoma: A Case Report

2010 ◽  
Vol 2010 ◽  
pp. 1-3 ◽  
Author(s):  
Nilufer Onak Kandemir ◽  
Banu Dogan Gun ◽  
Figen Barut ◽  
Nilgun Solak Tekin ◽  
Sukru Oguz Ozdamar
Keyword(s):  
Case Report ◽  
Kaposi's Sarcoma ◽  
Histopathological Examination ◽  
English Literature ◽  
Kaposi’S Sarcoma ◽  
Immunohistochemical Analysis ◽  
Cutaneous Lesions ◽  
Cutaneous Horn ◽  
Neoplastic Lesion ◽  
Macroscopic Examination

Cutaneous horn is characterized by the accumulation of abnormal keratinized material and may occur in association with a variety of benign, premalignant, and malignant cutaneous lesions. Cutaneous horn occurs very rarely in association with soft-tissue neoplasias. A cutaneous horn located on the toe was completely removed by excision in a 78-year-old male patient. Macroscopic examination revealed a hemorrhagic nodular lesion, 0.5 cm in diameter, located on the dermis underlying the cutaneous horn with a height of 1 cm. Histopathological examination revealed a neoplastic lesion consisting of fusiform cells and extravasated erythrocytes underlying the compact keratin mass. The immunohistochemical analysis showed immunoexpression of endothelial markers and HHV8 in fusiform cells. The case was evaluated as “cutaneous horn developed in a nodular stage Kaposi's sarcoma.” Our case is the second case of cutaneous horn related to Kaposi's sarcoma reported in the English literature and is presented in this case report with its clinical and histopathological features.

scholarly journals Acroangiodermatitis or pseudo-Kaposi’s sarcoma: a challenging diagnosis

2021 ◽  
Vol 12 (e) ◽  
pp. e72-e72
Author(s):  
Hanan Ragragui; Ouasmin ◽  
Soraya Aouali ◽  
Nada Zizi ◽  
Siham Dikhaye
Keyword(s):  
Blood Vessels ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Immunohistochemical Analysis ◽  
Lower Limbs ◽  
Vascular Lesions ◽  
Cutaneous Lesions ◽  
Clinical Variants ◽  
Proliferative Disease ◽  
Reactive Proliferation

Acroangiodermatitis (AAD), also referred to as pseudo-Kaposi’s sarcoma, is a vascular-proliferative disease characterized by reactive proliferation of small blood vessels in response to congenital or acquired vascular lesions. There are mainly two clinical variants of acroangiodermatitis; STEWART-BLUEFARB syndrome and the Malian type. There is clinical and histological similarity with Kaposi’s sarcoma hence the interest of immunohistochemical analysis. We report the case of a 40-year-old man with cutaneous lesions localized on the lower limbs. Clinical, dermoscopic, histological and immunohistochemical investigation led to a diagnosis of Kaposi-like acroangiodermatitis.

scholarly journals Transplant-associated penile Kaposi sarcoma managed with single agent paclitaxel chemotherapy: a case report

BMC Urology ◽  
2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Matthew A. Anderson ◽  
Tracey Ying ◽  
Kate Wyburn ◽  
Peter M. Ferguson ◽  
Madeleine C. Strach ◽  
...  
Keyword(s):  
Kaposi's Sarcoma ◽  
Single Agent ◽  
Lower Extremities ◽  
Kaposi’S Sarcoma ◽  
The Body ◽  
Cutaneous Lesions ◽  
Rare Presentation ◽  
Post Transplant ◽  
Transplant Patients ◽  
Disseminated Disease

Abstract Background Kaposi’s sarcoma is an uncommon complication in renal transplant patients, and typically presents with cutaneous lesions on the lower extremities. Penile involvement has been reported only rarely. Management of cutaneous-limited disease is primarily reduction of immunosuppression and conversion to an mTOR-inhibitor, whereas the treatment of disseminated disease in transplant patients is more variable. Case presentation A 75-year-old male, originally from Somalia, received a deceased-donor kidney transplant for diabetic and hypertensive nephropathy. Seven months post-transplant he presented with lower limb lesions, oedema and bilateral deep vein thromboses. He then developed a fast-growing painful lesion on his penile shaft. A biopsy of this lesion confirmed KS, and a PET scan demonstrated disseminated disease in the lower extremities, penis and thoracic lymph nodes. His tacrolimus was converted to sirolimus, and his other immunosuppression was reduced. He was treated with single agent paclitaxel chemotherapy in view of his rapidly progressing, widespread disease. The penile lesion completely resolved, and the lower extremity lesions regressed significantly. His kidney allograft function remained stable throughout treatment. Conclusion This case illustrates a rare presentation of an uncommon post-transplant complication and highlights the need for a high index of suspicion of KS in transplant patients presenting with atypical cutaneous lesions. It serves to demonstrate that the use of single agent paclitaxel chemotherapy, switch to an mTORi and reduction in immunosuppression where possible produces excellent short-term outcomes, adding to the body of evidence for this management strategy in disseminated Kaposi’s sarcoma.

scholarly journals Familial Kaposi’s Sarcoma: A Report of Five Cases from Greece

2014 ◽  
Vol 2014 ◽  
pp. 1-5
Author(s):  
Kalliopi Armyra ◽  
Anargyros Kouris ◽  
Arsinoi Xanthinaki ◽  
Alexandros Stratigos ◽  
Irene Potouridou
Keyword(s):  
Case Report ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Familial Cases ◽  
Familial Clustering ◽  
Southern Greece

Introduction. Familial cases of Kaposi’s sarcoma have rarely been reported. Kaposi’s sarcoma is not uncommon in Greece; its incidence is estimated at 0.20 per 100.000 habitants, showing an increased predominance in the Peloponnese, in Southern Greece.Case Report. We describe five cases of familial clustering of KS originating from Greece.Discussion. The pathogenesis of familial Kaposi’s sarcoma is still far from being completely understood. Genetic, environmental, and infectious factors have been incriminated.

scholarly journals Routine Histopathological Examination After Cholecystectomy

KYAMC Journal ◽  
2020 ◽  
Vol 10 (4) ◽  
pp. 184-187
Author(s):  
Md Abu Bakar Siddiue ◽  
Firoz Mahmud ◽  
M Fardil Hossain Faisal ◽  
Md Fazlur Rahman ◽  
Bidhan C Das ◽  
...  
Keyword(s):  
Observational Study ◽  
Gall Bladder ◽  
General Surgery ◽  
Histopathological Examination ◽  
Chronic Cholecystitis ◽  
Common Finding ◽  
Neoplastic Lesion ◽  
Medical University ◽  
Malignant Condition ◽  
Macroscopic Examination

Background: Cholecystectomy is one of the commonest surgeries in medical practice. Sometimes malignant condition cannot be assessed pre-operatively. Histopathology require for tissue diagnosis. Objective: To assess whether the histopathogical examination is really needed for all bladder specimens resected for cholelithiasis and cholecystitis. Materials and Methods: This observational study was carried out in the General Surgery Unit, Department of Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka from May, 2016 to April, 2017. A total number of 95 patients were included in this study. Results: Total of 95 gallbladder specimens were submitted for histopathological examination where 33.7% were males and 66.3 % were females with mean age of 46+12.86 years. Chronic cholecystitis was the most common finding in 91.6% of cases whereas Xanthogranulomatous 2.1%. Six of the gall bladders showed adenocarcinoma (6.3%), of which four had changes on ultrasound and macroscopic gall bladder analysis (MGAS) disturbances were found in 5 cases and 1 case was found incidentally on histopathological examination. On ultrasound, only four (66.66%) and peroperative macroscopic examination by surgeon only 5(83.3%) had a clue of carcinoma. Conclusion: It could be concluded that , routine histopathological examination of gallbladder after cholecystectomy is necessary as USG sometimes can not differentiate neoplastic lesion from inflammatory one. KYAMC Journal Vol. 10, No.-4, January 2020, Page 184-187

Classic Kaposi's sarcoma on the glans penis only: Case report

1997 ◽  
Vol 64 (1) ◽  
pp. 134-135
Author(s):  
E. Gastaldi ◽  
S. Benvenuti ◽  
B. Mennini ◽  
M. Iacoviello ◽  
M. Caviglione ◽  
...  
Keyword(s):  
Case Report ◽  
Kaposi's Sarcoma ◽  
Kaposi’S Sarcoma ◽  
Positive Patient ◽  
Glans Penis ◽  
Hiv Positive ◽  
Partial Penectomy

The Authors report a case of Kaposi's sarcoma presenting on the glans penis only in a non-HIV positive patient, who had not been treated with immuno-suppressive drugs. In our experience and according to a review of specific literature, choice treatment would seem to be a radiotherapeutic approach followed by partial penectomy in the event of recurrence.

scholarly journals Supraglottic Kaposi’s Sarcoma in HIV-Negative Patients: Case Report and Literature Review

2016 ◽  
Vol 2016 ◽  
pp. 1-3 ◽  
Author(s):  
Ela A. Server ◽  
Yusuf M. Durna ◽  
Ozgur Yigit ◽  
Erol R. Bozkurt
Keyword(s):  
Case Report ◽  
Kaposi's Sarcoma ◽  
Postoperative Radiotherapy ◽  
Disease Free Survival ◽  
Kaposi’S Sarcoma ◽  
Head Neck Cancer ◽  
Free Survival ◽  
Aryepiglottic Fold ◽  
Sarcoma Patient ◽  
Hiv Negative

This paper presents a case report of an HIV-negative, supraglottic Kaposi’s sarcoma patient. The 80-year-old male patient was admitted with complaints of hoarseness, difficulty in swallowing, and a stinging sensation in his throat for approximately six months. The endoscopic larynx examination revealed a lesion which had completely infiltrated the epiglottis, reached right aryepiglottic fold, was vegetating, pink and purple in color, multilobular, fragile, and shaped like a bunch of grapes, and partially blocked the bleeding airway passage. The case was discussed by the hospital’s head-neck cancer committee and a surgery decision was made. A tracheotomy was performed under local anesthesia before the operation due to respiratory distress and endotracheal intubation difficulty. Direct laryngoscopy showed that the mass was limited in the supraglottic area, had invaded the entire left aryepiglottic fold and one-third of the front right aryepiglottic fold, and completely covered epiglottis. It should be remembered that although rare, Kaposi’s sarcoma may be encountered in larynx malignancy cases. Disease-free survival may be achieved through local excision and postoperative radiotherapy.

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