scholarly journals Scalp Angiosarcoma Remission with Bevacizumab and Radiotherapy without Surgery: A Case Report and Review of the Literature

Sarcoma ◽  
2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Jocelyn T. De Yao ◽  
Danyu Sun ◽  
Angela T. Powell ◽  
Esther H. Rehmus
Keyword(s):  
Case Report ◽  
Poor Prognosis ◽  
Standard Treatment ◽  
Treatment Options ◽  
Angiogenesis Inhibitor ◽  
Success Rates ◽  
Review Of The Literature ◽  
Vascular Neoplasm

Angiosarcoma (AS) is a rare and aggressive vascular neoplasm with very poor prognosis. Patients with extensive cutaneous AS who are not surgical candidates have very limited options since there is no standard treatment. Treatment options include radiation, chemotherapy, and angiogenesis inhibitor with varying success rates. Here, we report a case an 88 year old patient with extensive scalp angiosarcoma having biopsy proven remission with bevacizumab and radiotherapy without undergoing surgery.

scholarly journals Sarcomatous Carcinoma of the Orbit: A Case Report and Review of the Literature

2015 ◽  
Vol 6 (2) ◽  
pp. 180-185
Author(s):  
Ninan Mathew ◽  
Mathen Mathew ◽  
Jon Farrah
Keyword(s):  
Case Report ◽  
Poor Prognosis ◽  
Advanced Disease ◽  
English Literature ◽  
Treatment Options ◽  
Malignant Cells ◽  
Review Of The Literature ◽  
Immunological Markers ◽  
Rare Tumours ◽  
The Right

Sarcomatous carcinomas (SCs) are rare tumours that contain malignant cells with epithelial and mesenchymal characteristics. SC rarely presents in the head and neck, and occurs even less often in the orbit. Only 8 cases of SCs located in the orbit or affecting the globe function have been described in the English literature. Here, we report a case of SC affecting the right orbit. SC is associated with a poor prognosis and advanced disease at presentation. Diagnosis is difficult, as histology often fails to definitively identify SC, necessitating a wide panel of molecular/immunological markers. Treatment options are generally aggressive but risky, and frequently yield poor results. Due to the rarity of SC, there has been little focus on the development of improved treatment options.

scholarly journals Primary Subcutaneous Umbilical Endometriosis: Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Lorenzo Capasso ◽  
Valerio Sciascia ◽  
Giuseppe Loiaco ◽  
Giovanni Guida ◽  
Francesco Iarrobino ◽  
...  
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Gold Standard ◽  
Care Setting ◽  
Standard Treatment ◽  
Treatment Options ◽  
Hormonal Treatment ◽  
Review Of The Literature ◽  
Adjuvant Hormonal Treatment ◽  
Umbilical Endometriosis

We report the case of a patient diagnosed with primary umbilical endometriosis intending to discuss the diagnostic and therapeutic management of this rare disease. A 45-year-old woman suffering from a painful swelling located in the umbilical region, with intact and normal cutaneous aspect, came to our attention. Ultrasonography of the umbilical region showed a nodule with a nonhomogeneous echotexture pattern. Partial omphalectomy was performed under local anesthesia in day care setting surgery. Histology confirmed the diagnosis of umbilical endometriosis. Pre- and postoperative clinical controls showed no evidence for other endometriosis localization. No medical treatment was administered. No signs of recurrence were observed after 5 years from surgery. A review of the literature of the last 10 years was generated based on MEDLINE research, selecting some specific keywords. Several lesions can occur in the umbilical region, and endometriosis has to be ruled out even in patients without any surgery in their medical history. Surgery is the gold standard treatment for this condition: partial and radical omphalectomy are the two treatment options. We believe that given the significant psychological and aesthetical value of the umbilicus, surgical treatment has to be tailored and in case of a small endometrial umbilical nodule, partial omphalectomy (local excision of the umbilical endometrial nodule) with a 3 mm free border, even without adjuvant hormonal treatment, could ensure adequate and effective treatment.

scholarly journals Case 2 – Ovarian small cell carcinoma: a case report and review of the literature

2017 ◽  
Vol 5 (1) ◽  
pp. 35-39
Author(s):  
Vanda Salutari ◽  
Patricia Pautier
Keyword(s):  
Case Report ◽  
Cell Carcinoma ◽  
Small Cell Carcinoma ◽  
Combination Chemotherapy ◽  
Poor Prognosis ◽  
Standard Treatment ◽  
Small Cell ◽  
Rare Tumor ◽  
Review Of The Literature ◽  
Carcinoma Of The Ovary

Ovarian small cell carcinoma is a rare tumor associated with poor prognosis. Although combination chemotherapy remains the cornerstone of treatment due to the rarity of these tumors, there is no evidencebased consensus for a standard treatment, although in the majority of cases platinum-based regimens are used. A case of small cell carcinoma of the ovary, hypercalcemic-type (SCCOHT), in a 22 year-old patient is reported.

Treatment options and long-term outcomes in pediatric spinal cord vascular malformations: a case report and review of the literature

2020 ◽  
Vol 36 (12) ◽  
pp. 3147-3152
Author(s):  
Helen J. Zhang ◽  
Nicole Silva ◽  
Elena Solli ◽  
Amanda C. Ayala ◽  
Luke Tomycz ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Case Report ◽  
Vascular Malformations ◽  
Treatment Options ◽  
Review Of The Literature ◽  
Long Term Outcomes

Malignant Rhabdoid Tumor of the Kidney in an Adult: A Case Report and Review of the Literature

2003 ◽  
Vol 127 (9) ◽  
pp. e371-e373 ◽  
Author(s):  
Hong Qi Peng ◽  
Albert E. Stanek ◽  
Saul Teichberg ◽  
Barry Shepard ◽  
Ellen Kahn
Keyword(s):  
Case Report ◽  
Aggressive Behavior ◽  
Poor Prognosis ◽  
Renal Tumor ◽  
Adult Population ◽  
Rhabdoid Tumor ◽  
Malignant Rhabdoid Tumor ◽  
Review Of The Literature ◽  
Electron Microscopic ◽  
Rhabdoid Tumors

Abstract Malignant rhabdoid tumor of the kidney is an uncommon renal tumor in children. The tumor has aggressive behavior and a poor prognosis and is extremely rare in adults; only 3 cases of renal rhabdoid tumors have been reported in adults. We describe here the microscopic, immunohistochemical, and electron microscopic characteristics of another case in a 38-year-old woman. This case reinforces the importance of recognizing this entity in the adult population.

Pyogenic Granuloma of the Foot with Satellitosis: A Role for Conservative Management

2011 ◽  
Vol 15 (1) ◽  
pp. 58-60
Author(s):  
Janice Bacher ◽  
Dalal Assaad ◽  
David N. Adam
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Conservative Management ◽  
Treatment Options ◽  
Pyogenic Granuloma ◽  
Conservative Approach ◽  
Review Of The Literature ◽  
Atypical Case ◽  
Over Time ◽  
Rule Out

Background: Pyogenic granuloma (PG) with satellitosis is a rare phenomenon that typically occurs in children and teenagers. It can be seen after excision or trauma to the original lesion. Objective: The aim is to review an atypical case of PG with satellitosis and to highlight a conservative approach to management. Methods: This article includes a case report of a 48-year-old woman developing PG with satellitosis in her right foot and includes a review of the literature. Results: There are few cases of PG with satellitosis in the literature. Our patient differs from most given her age and the location of the lesions. She was managed differently with a conservative observational approach, and, over time, her symptoms abated. Conclusion: PG with satellitosis can occur in varying patient populations with varying presentations. Although several treatment options exist, managing patients conservatively should be considered an approach to management. Early investigations should be conducted to rule out more sinister items in the differential diagnosis.

scholarly journals Successful treatment of thrombocytopenia with daratumumab after allogeneic transplant: a case report and literature review

2020 ◽  
Vol 4 (5) ◽  
pp. 815-818 ◽  
Author(s):  
Yazan Migdady ◽  
Asiri Ediriwickrema ◽  
Ryan Patrick Jackson ◽  
Wendy Kadi ◽  
Ridhi Gupta ◽  
...  
Keyword(s):  
Case Report ◽  
Literature Review ◽  
Successful Treatment ◽  
Standard Treatment ◽  
Treatment Options ◽  
Allogeneic Transplant ◽  
Novel Treatment ◽  
Short Course ◽  
Key Points ◽  
Lymphocyte Populations

Key Points A source of treatment refractoriness in immune cytopenias appears to be residual CD138/38-positive lymphocyte populations. A short course of daratumumab is a novel treatment of refractory thrombocytopenia after failure of standard treatment options.

scholarly journals Wandering Spleen and Organoaxial Gastric Volvulus after Morgagni Hernia Repair: A Case Report and Review of the Literature

2016 ◽  
Vol 2016 ◽  
pp. 1-9
Author(s):  
Noemi Cantone ◽  
Caterina Gulia ◽  
Vittorio Miele ◽  
Margherita Trinci ◽  
Vito Briganti
Keyword(s):  
Case Report ◽  
Diaphragmatic Hernia ◽  
Clinical Presentation ◽  
Treatment Options ◽  
Gastric Volvulus ◽  
Diagnostic Assessment ◽  
Wandering Spleen ◽  
Review Of The Literature ◽  
Morgagni Hernia ◽  
Assessment And Treatment

Wandering spleen and gastric volvulus are two rare entities that have been described in association with congenital diaphragmatic hernia. The diagnosis is difficult and any delay can result in ischemia and necrosis of both organs. We present a case of a 13-year-old girl, previously operated on for anterior diaphragmatic hernia and intrathoracic gastric volvulus, that presented to our service for a subdiaphragmatic gastric volvulus recurrence associated with a wandering spleen. In this report we reviewed the literature, analyzing the clinical presentation, diagnostic assessment, and treatment options of both conditions, in particular in the case associated with diaphragmatic hernia.

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