scholarly journals Fatal Myocarditis in Course ofPlasmodium falciparumInfection: Case Report and Review of Cardiac Complications in Malaria

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Paola Costenaro ◽  
Paolo Benedetti ◽  
Chiara Facchin ◽  
Carlo Mengoli ◽  
Giampietro Pellizzer
Keyword(s):  
Case Report ◽  
Myocardial Injury ◽  
Fatal Case ◽  
Falciparum Infection ◽  
Imported Malaria ◽  
Cardiac Complications ◽  
Potential Importance ◽  
Lymphocytic Myocarditis

We describe a fatal case of imported malaria where the sole finding revealed at thepostmortemevaluation was an acute lymphocytic myocarditis with myocardiolysis. This case recalls the potential importance of myocardial injury in the prognosis of malaria and prompts a reevaluation of current perspectives on the pathogenesis of severe falciparum infection. In the light of this, we have reviewed the cases of cardiac complications in malaria published to date.

scholarly journals Cardiac complications during the active phase of COVID-19: review of the current evidence

2021 ◽  
Author(s):  
Mohammad Said Ramadan ◽  
◽  
Lorenzo Bertolino ◽  
Tommaso Marrazzo ◽  
Maria Teresa Florio ◽  
...  
Keyword(s):  
Myocardial Injury ◽  
Myocardial Damage ◽  
Active Phase ◽  
Mortality Rates ◽  
Major Effect ◽  
Current Evidence ◽  
Cardiac Complications ◽  
Published Data ◽  
Improving Patient Care ◽  
Overall Mortality

AbstractGrowing reports since the beginning of the pandemic and till date describe increased rates of cardiac complications (CC) in the active phase of coronavirus disease 2019 (COVID-19). CC commonly observed include myocarditis/myocardial injury, arrhythmias and heart failure, with an incidence reaching about a quarter of hospitalized patients in some reports. The increased incidence of CC raise questions about the possible heightened susceptibility of patients with cardiac disease to develop severe COVID-19, and whether the virus itself is involved in the pathogenesis of CC. The wide array of CC seems to stem from multiple mechanisms, including the ability of the virus to directly enter cardiomyocytes, and to indirectly damage the heart through systemic hyperinflammatory and hypercoagulable states, endothelial injury of the coronary arteries and hypoxemia. The induced CC seem to dramatically impact the prognosis of COVID-19, with some studies suggesting over 50% mortality rates with myocardial damage, up from ~ 5% overall mortality of COVID-19 alone. Thus, it is particularly important to investigate the relation between COVID-19 and heart disease, given the major effect on morbidity and mortality, aiming at early detection and improving patient care and outcomes. In this article, we review the growing body of published data on the topic to provide the reader with a comprehensive and robust description of the available evidence and its implication for clinical practice.

scholarly journals Hypocalcemic cardiomyopathy after parathyroidectomy in a patient with uremia: A case report and literature review

2020 ◽  
Vol 48 (7) ◽  
pp. 030006052094211
Author(s):  
Wei Zhang ◽  
Feng Xue ◽  
Quandong Bu ◽  
Xuemei Liu
Keyword(s):  
Heart Failure ◽  
Case Report ◽  
Secondary Hyperparathyroidism ◽  
Calcium Supplementation ◽  
Severe Heart Failure ◽  
Cardiac Complications ◽  
Refractory Heart Failure ◽  
First Case ◽  
Insight Into

Hypocalcemia is a rare, but reversible, cause of dilated cardiomyopathy. Although cardiomyopathy may cause severe heart failure, calcium supplementation can reverse heart failure. We report here a patient with uremia and secondary hyperparathyroidism, who was complicated by persistent hypocalcemia and refractory heart failure. The cardiac failure was refractory to treatment with digitalis and diuretics, but dramatically responded to calcium therapy and restoration of normocalcemia. As a result, the patient was eventually diagnosed with hypocalcemic cardiomyopathy. To the best of our knowledge, this is the first case of this disease to be reported in a patient with uremia. Findings from our case may help clinicians to better understand hypocalcemic cardiomyopathy. Our case might also provide new insight into long-term cardiac complications and prognoses of patients undergoing parathyroidectomy due to secondary hyperparathyroidism.

scholarly journals Fatal case of toxic epidermal necrolysis induced by ciproflfl oxacin in a child

2021 ◽  
Vol 12 (Supp 1) ◽  
pp. 26-29
Author(s):  
Thomas Schiestel
Keyword(s):  
Case Report ◽  
Toxic Epidermal Necrolysis ◽  
Adverse Reactions ◽  
Pediatric Population ◽  
Fatal Case ◽  
Stevens Johnson Syndrome ◽  
Delayed Treatment ◽  
Drug Eruptions ◽  
Johnson Syndrome ◽  
Life Threatening

Bullous drug eruptions such as Toxic Epidermal Necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare but known adverse reactions of fluoroquinolones. Although uncommon, TEN can be life-threatening for the patient, especially in the context of delayed treatment and in fragile patients such as the pediatric population. In the present case, TEN occurred in a 13-year-old girl with no medical history following initiation of ciprofloxacin treatment for an inguinal cyst. We hope that the case report will make interrogate the practices concerning the use of antibiotics, in particular fluoroquinolones in the context of an use not prescribed by the Marketing Authorization of the drug in children.

scholarly journals A fatal case of disseminated chronic Q fever: a case report and brief review of the literature

Infection ◽  
2016 ◽  
Vol 44 (5) ◽  
pp. 677-682 ◽  
Author(s):  
Stephan P. Keijmel ◽  
Ruud P. H. Raijmakers ◽  
Teske Schoffelen ◽  
Maria C. W. Salet ◽  
Chantal P. Bleeker-Rovers
Keyword(s):  
Case Report ◽  
Q Fever ◽  
Fatal Case ◽  
Review Of The Literature ◽  
Chronic Q Fever

Fatal case of pancreatic panniculitis caused by occult neuroendocrine tumor in the corresponding organ: A case report and review of the published work

2020 ◽  
Author(s):  
Hiroshi Kasamatsu ◽  
Noritaka Oyama ◽  
Minoru Hasegawa ◽  
Yohei Oku ◽  
Genki Inoue ◽  
...  
Keyword(s):  
Case Report ◽  
Neuroendocrine Tumor ◽  
Fatal Case ◽  
Pancreatic Panniculitis

scholarly journals Added value of subjective assessed functional capacity before non-cardiac surgery in predicting postoperative myocardial injury

2020 ◽  
pp. 204748732090691
Author(s):  
Marije Marsman ◽  
Judith AR van Waes ◽  
Remco B Grobben ◽  
Corien SA Weersink ◽  
Wilton A van Klei
Keyword(s):  
Myocardial Infarction ◽  
Cardiac Surgery ◽  
Functional Capacity ◽  
Myocardial Injury ◽  
Added Value ◽  
Cardiac Complications ◽  
Tertiary Referral Hospital ◽  
Postoperative Myocardial Infarction ◽  
Observational Cohort ◽  
One Year

Background Functional capacity is used as an indicator for cardiac testing before non-cardiac surgery and is often performed subjectively. However, the value of subjectively estimated functional capacity in predicting cardiac complications is under debate. We determined the predictive value of subjectively assessed functional capacity on postoperative cardiac complications and mortality. Design An observational cohort study in patients aged 60 years and over undergoing elective inpatient non-cardiac surgery in a tertiary referral hospital. Methods Subjective functional capacity was determined by anaesthesiologists. The primary outcome was postoperative myocardial injury. Secondary outcomes were postoperative inhospital myocardial infarction and one year mortality. Logistic regression analysis and area under the receiver operating curves were used to determine the added value of functional capacity. Results A total of 4879 patients was included; 824 (17%) patients had a poor subjective functional capacity. Postoperative myocardial injury occurred in 718 patients (15%). Poor functional capacity was associated with myocardial injury (relative risk (RR) 1.7, 95% confidence interval (CI) 1.5–2.0; P < 0.001), postoperative myocardial infarction (RR 2.9, 95% CI 1.9–4.2; P < 0.001) and one year mortality (RR 1.7, 95% CI 1.4–2.0; P < 0.001). After adjustment for other predictors, functional capacity was still a significant predictor for myocardial injury (odds ratio (OR) 1.3, 95% CI 1.0–1.7; P = 0.023), postoperative myocardial infarction (OR 2.0, 95% CI 1.3–3.0; P = 0.002) and one year mortality (OR 1.4, 95% CI 1.1–1.8; P = 0.003), but had no added value on top of other predictors. Conclusions Subjectively assessed functional capacity is a predictor of postoperative myocardial injury and death, but had no added value on top of other preoperative predictors.

scholarly journals Case Report: Essential Pulmonary Hemosiderosis

Blood ◽  
1951 ◽  
Vol 6 (7) ◽  
pp. 665-671 ◽  
Author(s):  
B. JONSSON ◽  
B. VAHLQUIST ◽  
K. AGNER
Keyword(s):  
Case Report ◽  
Iron Deficiency ◽  
Fatal Case ◽  
Pulmonary Hemosiderosis ◽  
Deficiency Type

Abstract The authors report a fatal case of essential pulmonary hemosiderosis in a 5 year old boy. The child showed typical signs of the disease with relapsing pulmonary attacks with hemoptysis and pronounced anemia of iron deficiency type. Huge amounts of hydrolyzable iron were found in the lungs.

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