Pharmacophore Modelling and Synthesis of Quinoline-3-Carbohydrazide as Antioxidants
2011 ◽
Vol 2011
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pp. 1-10
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Keyword(s):
From well-known antioxidants agents, we developed a first pharmacophore model containing four common chemical features: one aromatic ring and three hydrogen bond acceptors. This model served as a template in virtual screening of Maybridge and NCI databases that resulted in selection of sixteen compounds. The selected compounds showed a good antioxidant activity measured by three chemical tests: DPPH radical, OH∘ radical, and superoxide radical scavenging. New synthetic compounds with a good correlation with the model were prepared, and some of them presented a good antioxidant activity.
2017 ◽
Vol 21
(2)
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pp. 11-18
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EVALUATION OF IN VITRO ANTIOXIDANT ACTIVITY OF A MEDICINAL HERB, WEDELIA CHINENSIS (OSBECK) MERRILL.
2018 ◽
Vol 11
(10)
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pp. 433
2020 ◽
Vol 2020
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pp. 1-16
2013 ◽
Vol 781-784
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pp. 1294-1297
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2010 ◽
Vol 9
(3)
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pp. 457-460
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