scholarly journals Arteriovenous Malformation of the Oral Cavity

2014 ◽  
Vol 2014 ◽  
pp. 1-5 ◽  
Author(s):  
S. M. Manjunath ◽  
Sujan Shetty ◽  
Ninad J. Moon ◽  
Bhushan Sharma ◽  
Kiran Kumar Metta ◽  
...  
Keyword(s):  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Vascular Anomaly ◽  
Benign Disease ◽  
Vascular Tumors ◽  
Management Approach ◽  
Lymphatic Capillary ◽  
Clinical Behavior ◽  
Specific Morphology

Vascular anomalies are a heterogeneous group of congenital blood vessel disorders more typically referred to as birthmarks. Subcategorized into vascular tumors and malformations, each anomaly is characterized by specific morphology, pathophysiology, clinical behavior, and management approach. Hemangiomas are the most common vascular tumors. Lymphatic, capillary, venous, and arteriovenous malformations make up the majority of vascular malformations. Arteriovenous malformation of the head and neck is a rare vascular anomaly but when present is persistent and progressive in nature and can represent a lethal benign disease. Here we present a case report of a 25-year-old male patient with arteriovenous malformation involving the base of tongue.

scholarly journals Hemangiomas and Vascular Malformations: Current Theory and Management

2012 ◽  
Vol 2012 ◽  
pp. 1-10 ◽  
Author(s):  
Gresham T. Richter ◽  
Adva B. Friedman
Keyword(s):  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Vascular Tumor ◽  
Current Theory ◽  
Vascular Anomalies ◽  
Theory And Practice ◽  
Vascular Tumors ◽  
Management Approach ◽  
Lymphatic Capillary ◽  
Specific Morphology

Vascular anomalies are a heterogeneous group of congenital blood vessel disorders more typically referred to as birthmarks. Subcategorized into vascular tumors and malformations, each anomaly is characterized by specific morphology, pathophysiology, clinical behavior, and management approach. Hemangiomas are the most common vascular tumor. Lymphatic, capillary, venous, and arteriovenous malformations make up the majority of vascular malformations. This paper reviews current theory and practice in the etiology, diagnosis, and treatment of these more common vascular anomalies.

scholarly journals Peripheral Vascular Anomalies – Essentials in Periinterventional Imaging

2019 ◽  
Vol 192 (02) ◽  
pp. 150-162 ◽  
Author(s):  
Maliha Sadick ◽  
Daniel Overhoff ◽  
Bettina Baessler ◽  
Naema von Spangenberg ◽  
Lena Krebs ◽  
...  
Keyword(s):  
Therapeutic Approach ◽  
Vascular Malformations ◽  
Vascular Anomaly ◽  
Flow Dynamics ◽  
Vascular Anomalies ◽  
Vascular Tumors ◽  
Slow Flow ◽  
Peripheral Vascular ◽  
Fast Flow ◽  
Selection Of

Background Peripheral vascular anomalies represent a rare disease with an underlying congenital mesenchymal and angiogenetic disorder. Vascular anomalies are subdivided into vascular tumors and vascular malformations. Both entities include characteristic features and flow dynamics. Symptoms can occur in infancy and adulthood. Vascular anomalies may be accompanied by characteristic clinical findings which facilitate disease classification. The role of periinterventional imaging is to confirm the clinically suspected diagnosis, taking into account the extent and location of the vascular anomaly for the purpose of treatment planning. Method In accordance with the International Society for the Study of Vascular Anomalies (ISSVA), vascular anomalies are mainly categorized as slow-flow and fast-flow lesions. Based on the diagnosis and flow dynamics of the vascular anomaly, the recommended periinterventional imaging is described, ranging from ultrasonography and plain radiography to dedicated ultrafast CT and MRI protocols, percutaneous phlebography and transcatheter angiography. Each vascular anomaly requires dedicated imaging. Differentiation between slow-flow and fast-flow vascular anomalies facilitates selection of the appropriate imaging modality or a combination of diagnostic tools. Results Slow-flow congenital vascular anomalies mainly include venous and lymphatic or combined malformations. Ultrasound and MRI and especially MR-venography are essential for periinterventional imaging. Arteriovenous malformations are fast-flow vascular anomalies. They should be imaged with dedicated MR protocols, especially when extensive. CT with 4D perfusion imaging as well as time-resolved 3D MR-A allow multiplanar perfusion-based assessment of the multiple arterial inflow and venous drainage vessels of arterio-venous malformations. These imaging tools should be subject to intervention planning, as they can reduce procedure time significantly. Fast-flow vascular tumors like hemangiomas should be worked up with ultrasound, including color-coded duplex sonography, MRI and transcatheter angiography in case of a therapeutic approach. In combined malformation syndromes, radiological imaging has to be adapted according to the dominant underlying vessels and their flow dynamics. Conclusion Guide to evaluation of flow dynamics in peripheral vascular anomalies, involving vascular malformations and vascular tumors with the intention to facilitate selection of periinterventional imaging modalities and diagnostic and therapeutic approach to vascular anomalies. Key Points:  Citation Format

Cultured Endothelial Cells From Human Arteriovenous Malformations Have Defective Growth Regulation

Blood ◽  
1999 ◽  
Vol 94 (6) ◽  
pp. 2020-2028
Author(s):  
Marie-Paule Wautier ◽  
Bernadette Boval ◽  
Olivier Chappey ◽  
Odile Enjolras ◽  
Nicolas Wernert ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Arteriovenous Malformations ◽  
Cell Adhesion Molecule ◽  
Transforming Growth Factor ◽  
Vascular Malformations ◽  
Proliferation Rate ◽  
Intercellular Adhesion Molecule ◽  
Vascular Tumors

Vascular malformations are frequent in newborns, and they persist throughout life, which differentiates them from vascular tumors (eg, hemangiomas). Arteriovenous malformations are high-flow vascular malformations. They are considered nonmalignant but can expand and become a significant clinical risk when extensive. To characterize endothelial cells from arteriovenous malformations (AMEC), we cultured cells obtained from surgical specimens and studied their properties. After selection, the cells that grew out from explants had phenotypic and antigenic features (platelet endothelial cell adhesion molecule, von Willebrand factor) of human endothelial cells. Their spontaneous proliferation rate was higher (1.8 to 6.4 times) than that of human umbilical vein, arterial, or microvascular endothelial cells. The proliferation rate of AMEC was not sensitive to the inhibitory activity of various cytokines (interleukin-1β, tumor necrosis factor-, transforming growth factor-β, Interferon-γ). In basal conditions, intercellular adhesion molecule (ICAM-1) was detected at a higher level of expression (6- to 10-fold) on AMEC, but these cells failed to express E-selectin or the vascular cell adhesion molecule (VCAM-1) after cytokine stimulation. Expression of c-ets-1 proto-oncogene was shown by in situ hybridization. The low response to cytokines, the higher propensity to proliferate, and the ets-1 expression suggest that AMEC have a defective regulation of proliferation that may be due to a reduced apoptotic process.

scholarly journals Klippel-Trénaunay Syndrome with Intracranial Arteriovenous Malformation: A Rare Presentation

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Mahniya F. Sadiq ◽  
Waqas Shuaib ◽  
Muhammad H. Tiwana ◽  
Jamlik-Omari Johnson ◽  
Faisal Khosa
Keyword(s):  
Congenital Anomaly ◽  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
The United States ◽  
Slow Flow ◽  
Rare Presentation ◽  
Intracranial Arteriovenous Malformation ◽  
Case Presentation ◽  
Klippel Trenaunay Syndrome

Klippel-Trénaunay syndrome (KTS) is a rare vascular congenital anomaly affecting less than 200,000 people in the United States. Vascular malformations associated with KTS tend to affect slow flow systems: venous, capillary, and lymphatic systems. The nature of the syndrome leads to a higher risk for the development of arteriovenous malformations. Our case presentation describes a patient with KTS and an associated rare presentation of intraventricular arteriovenous malformation (AVM).

Oligodendroglial Proliferative Abnormality Associated with Arteriovenous Malformation: Report of Three Cases with Review of the Literature

Neurosurgery ◽  
1988 ◽  
Vol 23 (6) ◽  
pp. 781-785 ◽  
Author(s):  
M. Nazek ◽  
T. I. Mandybur ◽  
S. Kashiwagi
Keyword(s):  
White Matter ◽  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Careful Consideration ◽  
Pathological Features ◽  
Review Of The Literature ◽  
Cerebral Arteriovenous Malformations ◽  
Biopsy Material ◽  
Clinical And Pathological Features

Abstract A peculiar nonneoplastic oligodendroglial proliferative abnormality associated with cerebral arteriovenous malformations (AVMs) was present in three patients. Histological examination of biopsy material revealed dense oligodendroglial tissue reminiscent of oligodendroglioma in the white matter adjoining the AVMs. Careful consideration of clinical and pathological features suggested that the evidence was insufficient to qualify the lesion as truly neoplastic (oligodendroglioma); rather, a tissue collapse or a hamartomatous proliferation could be considered to be its cause. The literature contains 14 instances of various vascular malformations associated with primary brain tumors, 5 of which were diagnosed as oligodendrogliomas. It is possible, however, that some of the cases reported in the literature constitute oligodendroglial abnormality similar to that observed in our cases rather than genuine oligodendrogliomas. Attention is drawn to this interesting and prognostically important phenomenon.

scholarly journals Surgical management of extracranial arteriovenous malformations.

2021 ◽  
pp. 16-20
Keyword(s):  
Arteriovenous Malformation ◽  
Surgical Management ◽  
Arteriovenous Malformations ◽  
Vascular Anomaly ◽  
Psychological Disorders

Arteriovenous malformation (AVM) is defined as vascular anomaly that shunts blood from arteries directly to veins. Infiltrating and diffuse extracranial AVMs may, result in several cosmetic, functional, and psychological disorders. In this report, we tried to describe our experience with the AVM surgical management.

Cultured Endothelial Cells From Human Arteriovenous Malformations Have Defective Growth Regulation

Blood ◽  
1999 ◽  
Vol 94 (6) ◽  
pp. 2020-2028 ◽  
Author(s):  
Marie-Paule Wautier ◽  
Bernadette Boval ◽  
Olivier Chappey ◽  
Odile Enjolras ◽  
Nicolas Wernert ◽  
...  
Keyword(s):  
Endothelial Cells ◽  
Cell Adhesion ◽  
Adhesion Molecule ◽  
Arteriovenous Malformations ◽  
Cell Adhesion Molecule ◽  
Transforming Growth Factor ◽  
Vascular Malformations ◽  
Proliferation Rate ◽  
Intercellular Adhesion Molecule ◽  
Vascular Tumors

Abstract Vascular malformations are frequent in newborns, and they persist throughout life, which differentiates them from vascular tumors (eg, hemangiomas). Arteriovenous malformations are high-flow vascular malformations. They are considered nonmalignant but can expand and become a significant clinical risk when extensive. To characterize endothelial cells from arteriovenous malformations (AMEC), we cultured cells obtained from surgical specimens and studied their properties. After selection, the cells that grew out from explants had phenotypic and antigenic features (platelet endothelial cell adhesion molecule, von Willebrand factor) of human endothelial cells. Their spontaneous proliferation rate was higher (1.8 to 6.4 times) than that of human umbilical vein, arterial, or microvascular endothelial cells. The proliferation rate of AMEC was not sensitive to the inhibitory activity of various cytokines (interleukin-1β, tumor necrosis factor-, transforming growth factor-β, Interferon-γ). In basal conditions, intercellular adhesion molecule (ICAM-1) was detected at a higher level of expression (6- to 10-fold) on AMEC, but these cells failed to express E-selectin or the vascular cell adhesion molecule (VCAM-1) after cytokine stimulation. Expression of c-ets-1 proto-oncogene was shown by in situ hybridization. The low response to cytokines, the higher propensity to proliferate, and the ets-1 expression suggest that AMEC have a defective regulation of proliferation that may be due to a reduced apoptotic process.

scholarly journals A Case of Arteriovenous Malformation of the Nasal Tip

2020 ◽  
Vol 63 (3) ◽  
pp. 123-128
Author(s):  
Yangseop Noh ◽  
Gwanghui Ryu ◽  
Hyo Yeol Kim
Keyword(s):  
Arteriovenous Malformation ◽  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Treatment Plan ◽  
Venous Malformation ◽  
Successful Outcome ◽  
Nasal Tip ◽  
Appropriate Treatment ◽  
Superselective Embolization ◽  
Fast Flow

Arteriovenous malformation is a vascular malformation with fast-flow shunt from the artery to the vein. Extracranial arteriovenous malformation in the head and neck area is rare disease compared to other vascular malformations such as venous malformation or lymphatic malformation. Extracranial arteriovenous malformations especially on face can cause aesthetic problems, therefore surgeons should consider an importance of cosmetic outcome and choose appropriate treatment plan. We report a case of 51-year-old male who presented with enlarged nasal tip diagnosed arteriovenous malformation. This case showed successful outcome after combination therapy consisted of superselective embolization and surgical resection.

scholarly journals How we approach localized vascular anomalies

2021 ◽  
Author(s):  
Kristy Pahl ◽  
Waleska Pabon-Ramos ◽  
Michael Jeng
Keyword(s):  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Management Strategies ◽  
Vascular Anomalies ◽  
Vascular Tumors ◽  
Imaging Features ◽  
Diagnosis And Management

Vascular anomalies are a group of disorders divided into two distinct subtypes: vascular tumors and vascular malformations. Vascular tumors are proliferative in nature, while malformations are non-proliferative. Simple, localized vascular malformations refer to a group of malformations that are localized to a single area of involvement. These simple malformations include capillary, lymphatic, venous, and arteriovenous malformations. The pediatric hematologist and oncologist is becoming increasingly involved in the diagnosis and management of these disorders. This review presents four cases as a means to discuss the diagnosis, clinical and imaging features, and management strategies of simple, localized vascular malformations.

Spinal arteriovenous malformations: new classification and surgical treatment

2006 ◽  
Vol 20 (5) ◽  
pp. 1-17 ◽  
Author(s):  
Yuri P. Zozulya ◽  
Eugene I. Slin'ko ◽  
Iyad I. Al-Qashqish
Keyword(s):  
Surgical Treatment ◽  
Arteriovenous Malformations ◽  
Vascular Malformations ◽  
Three Dimensional ◽  
Vascular Tumors ◽  
Type I ◽  
Cavernous Malformations ◽  
Patients Âgés ◽  
Spinal Vascular Malformations ◽  
Spinal Arteriovenous Malformations

Object Spinal vascular malformations represent rare and insufficiently studied pathological entities characterized by considerable variation. Insufficient study of this disease is connected with the complexity of its diagnosis, which restricts the development of surgical treatments that are differentiated according to the type of malformation. Great difficulties are caused by the lack of a clear structural–hemodynamic classification of spinal arteriovenous malformations (AVMs). At present the classification created between 1991 and 1998 by the combined efforts of different authors is the most widely used one. According to this classification, four categories are distinguishable: Type I, dural arteriovenous fistulas (AVFs); Type II, intramedullary glomus AVMs; Type III, juvenile or combined AVMs; and Type IV, intradural perimedullary AVFs. Vascular tumors are also classified, as follows: hemangiomas, hemangioblastomas, angiosarcomas, hemangiopericytomas, angiofibromas, angiolipomas, and hemangioendotheliomas, as well as cavernous malformations. Methods In this study the authors analyze the diagnostic data and results of treatment in 91 patients with AVMs and AVFs who were treated at the Institute of Neurosurgery between 1995 and 2005. The patients' ages ranged from 9 to 83 years; the mean age was 42.9 years. For spinal vascular malformations we devised a classification that took into account the aforementioned features of AVMs: the anatomical characteristics of a malformation and its angiostructural and hemodynamic features. In all patients the neuroimaging modalities used in the investigation of their lesions included magnetic resonance (MR) imaging and selective spinal angiography. Three-dimensional computerized tomography angiography studies were obtained in 14 patients, and MR angiography was used in 17. Conclusions For successful surgical treatment of spinal AVMs it is necessary to obtain data about their localization, vascular structure, and hemodynamics that are as complete as possible. This information will promote the use of optimum surgical procedures and the latest methods of microsurgical and endovascular interventions, with treatments differentiated according to the type of malformation. One should try to use the least invasive endovascular approach in these cases,where possible, to occlude the AVM or reduce the intensity of blood flow by means of embolization. To perform an AVM resection or occlusion, one should use a direct approach to the malformation, blocking only the vessels supplying blood to the malformation and preserving the vessels feeding the spinal cord.

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