scholarly journals Atypical Presentation of Cat-Scratch Disease in an Immunocompetent Child with Serological and Pathological Evidence

2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Serkan Atıcı ◽  
Eda Kepenekli Kadayıfcı ◽  
Ayşe Karaaslan ◽  
Muhammed Hasan Toper ◽  
Cigdem Ataizi Celikel ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Bartonella Henselae ◽  
Atypical Presentation ◽  
Cat Scratch Disease ◽  
Pathological Findings ◽  
Immunocompetent Child ◽  
Hepatic Mass ◽  
Appropriate Treatment

Typical cat-scratch disease (CSD) is characterized by local lymphadenopathy following the scratch or bite from a cat or kitten. An atypical presentation which includes liver and/or spleen lesions is rarely reported in an immunocompetent child. Systemic CSD may mimic more serious disorders like malignancy or tuberculosis. Although a diagnosis is difficult to establish in systemic CSD, an early diagnosis and an appropriate treatment are important to prevent complications.Bartonella henselaeis difficult to culture, and culture is not routinely recommended. Clinical, serological, radiological, and pathological findings are used for the diagnosis of CSD. Herein we present a case of systemic CSD presenting with hepatic mass in an immunocompetent child. The differential diagnosis is made by serological and pathological evidence. He was successfully treated with gentamicin (7.5 mg/kg) and rifampin (15 mg/kg) for six weeks.

scholarly journals Bartonella Endocarditis Mimicking Crescentic Glomerulonephritis with PR3-ANCA Positivity

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Joseph Vercellone ◽  
Lisa Cohen ◽  
Saima Mansuri ◽  
Ping L. Zhang ◽  
Paul S. Kellerman
Keyword(s):  
Crescentic Glomerulonephritis ◽  
Bartonella Henselae ◽  
Kidney Injury ◽  
Flank Pain ◽  
Cat Scratch Disease ◽  
Urinary Sediment ◽  
Appropriate Treatment ◽  
Antibody Titers ◽  
Complex Deposition ◽  
Culture Negative

Bartonella henselae is a fastidious organism that causes cat scratch disease, commonly associated with fever and lymphadenopathy but, in rare instances, also results in culture-negative infectious endocarditis. We describe a patient who presented with flank pain, splenic infarct, and acute kidney injury with an active urinary sediment, initially suspicious for vasculitis, which was subsequently diagnosed as B. henselae endocarditis. Bartonella endocarditis may present with a crescentic glomerulonephritis (GN) and elevated PR3-ANCA antibody titers, mimicking ANCA-associated GN, with 54 cases reported in the literature. Unique to our case in this series is a positive PR3-ANCA antibody despite a negative IIF-ANCA. Thus, the presentation of Bartonella can mimic ANCA-associated GN, and renal biopsy showing immune complex deposition is critical for diagnosis and appropriate treatment.

scholarly journals Cat-Scratch Disease Pneumonia: An Atypical Presentation

2020 ◽  
Vol 7 (09) ◽  
pp. 4966-4972
Author(s):  
Fotis Konstantinou, ◽  
Ioanna Skrapari ◽  
Asimoula Megkou ◽  
Evangelos Kokkinakis
Keyword(s):  
Bartonella Henselae ◽  
Rare Complication ◽  
Cutaneous Lesion ◽  
Pulmonary Involvement ◽  
Immunocompetent Patient ◽  
Common Disease ◽  
Atypical Presentation ◽  
Cat Scratch Disease ◽  
Review Of The Literature ◽  
Uncommon Presentation

Purpose: Cat-scratch disease is caused by Bartonella henselae infection and it commonly presents in children with a mild cutaneous lesion and adjacent lymphadenitis. It has rarely been observed that it can present as a disseminated infection, such as encephalitis or pneumonia. We present a case report of a 35-year old, immunocompetent, patient who suffered pneumonia and encephalitis, resulting from Bartonella henselae infection. We also present a review of the literature published regarding this rare complication. Methods: We’ve searched the literature in the databases of Pubmed and Google Scholar to find articles that report pulmonary presentations of cat-scratch disease. Results: We’ve found only 16 other reported similar cases with pulmonary involvement in cat-scratch disease. Conclusions: Pulmonary presentation in cat-scratch disease is an uncommon presentation of a common disease, and it should be ruled out, even in cases it seems unlikely.  

scholarly journals Atypical presentation of bartonellosis with hepatolienal lesions

2021 ◽  
Vol 20 (1) ◽  
pp. 136-144
Author(s):  
M. A. Lunyakova ◽  
V. G. Demikhov ◽  
N. V. Inyakova ◽  
E. A. Panina
Keyword(s):  
Clinical Course ◽  
Bartonella Henselae ◽  
Human Infection ◽  
Atypical Presentation ◽  
Cat Scratch Disease ◽  
Neurological Manifestations ◽  
Gram Negative ◽  
Duration Of Therapy ◽  
Night Sweats ◽  
History Of

Cat scratch disease is caused by the gram-negative intracellular bacterium Bartonella henselae (B. henselae). Human infection occurs mainly through cat scratches and bites. In typical cases, the clinical course is presented by a primary affect on the skin and regional lymphadenitis. The atypical presentation of infection can occur with fever, abdominal, ocular and neurological manifestations. A special feature of the abdominal form is the presence of solitary or multiple hypo/anechoic foci of different size and shape in the liver and spleen. B. henselae infection is one of the most common mimics of malignant lymphoma, when the spleen is involved in combination with B symptoms (weight loss, night sweats and prolonged fever). A history of recent contact with cats and diagnostic IgG titers to B. henselae indicate infection. There is no consensus on the choice of antimicrobial drug and the duration of therapy for systemic forms. The article presents its own experience in the diagnosis and treatment of such patients. The patient's parents agreed to use the information, including the child's photo, in scientific research and publications. 

scholarly journals Encephalopathy an Atypical Presentation of Intussusception: A Case Report

2020 ◽  
Vol 8 (1) ◽  
pp. 41-44
Author(s):  
Venma Mampilly ◽  
Sasikumar Manalumukkil Sankaran ◽  
Ramaraj Subbiah
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Early Diagnosis ◽  
Pediatric Emergency ◽  
Acute Onset ◽  
Differential Diagnoses ◽  
Atypical Presentation ◽  
Neurological Manifestations ◽  
Abdominal Symptoms

Background: Intussusception Encephalopathy is a pediatric emergency where a stuporous child presents with or without abdominal symptoms. Neurological manifestations of intussusception are an atypical presentation of this condition. It often misleads clinicians to other differential diagnoses of encephalopathy. The Case: We present to you a case of an 11-month-old child presented with encephalopathy, acute in onset with underlying intussusception. Conclusion: Intussusception encephalopathy is a pediatric emergency. It should be kept as a differential diagnosis when a child presents with complaints of acute onset of drowsiness with or without abdominal symptoms. Early diagnosis could save grave complications and improve the prognosis.

Strontium 87m Scanning of Pelvic Bones

1968 ◽  
Vol 07 (01) ◽  
pp. 28-36 ◽  
Author(s):  
Władysław Jasiński ◽  
Janina Malinowska ◽  
Henryk Mackiewicz ◽  
Henryk Siwicki ◽  
Krystyna Lukawska
Keyword(s):  
Body Weight ◽  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Femoral Neck ◽  
Early Period ◽  
Early Recurrence ◽  
Physical Activities ◽  
External Irradiation ◽  
Pelvic Bones ◽  
Strontium 87M

SummaryThe purpose of this investigation was to study the accumulation of 87mSr in the proximal parts of the femoral bones of patients treated previously by external irradiation due to cancer of the uterine cervix. It was assumed that this method may be used in the future for the early diagnosis of postirradiation changes of bone (osteoradionecrosis).The incidence of postirradiation changes of the femoral neck among 5735 patients treated between 1950 and 1961 at the Department of Gynaecology of the Institute, was 0.8%. In the early period of postirradiation changes the patients complain only of pain and limitation of physical activities. If radiological and gynaecological findings were negative, the differential diagnosis between early recurrence and early osteoradionecrosis became impossible.49 selected patients were scanned after intravenous injection of 10—115 μCi of 87mSr per kg of body weight (0.5 up to 6.0 mCi). Illustrative cases of normal pelvic bones as well as postirradiation changes are presented and discussed. The authors conclude that the findings justify further systematic studies on the morphology of accumulation of 87mSr in the bones.

scholarly journals FM Combined With NIHSS Score Contributes to Early AIS Diagnosis and Differential Diagnosis of Cardiogenic and Non-Cardiogenic AIS

2021 ◽  
Vol 27 ◽  
pp. 107602962110001
Author(s):  
Dan Wu ◽  
Yong’e Liu
Keyword(s):  
Differential Diagnosis ◽  
Early Diagnosis ◽  
Diagnostic Efficacy ◽  
Stroke Treatment ◽  
Nihss Score ◽  
Stroke Group ◽  
Diagnosis And Classification ◽  
Toast Classification ◽  
Thrombotic Diseases ◽  
D Dimer

A growing researchers have suggested that fibrin monomer (FM) plays an important role in early diagnosis of thrombotic diseases. We explored the application of FM in the diagnosis and classification of acute ischemic stroke (AIS). The differences in FM, D-dimer, and NIHSS scores between different TOAST (Trial of ORG 10172 in Acute Stroke Treatment) types were analyzed with one-way ANOVA; the correlation between FM, D-dimer and NIHSS score in patients with different TOAST classification was analyzed by Pearson linear correlation. The ROC curve was utilized to analyze the diagnostic performance. 1. FM was more effective in diagnosing patients with AIS than D-dimer. 2. The FM level in cardiogenic AIS was significantly different from that in non-cardiogenic patients ( P < 0.05); the NIHSS score in cardiogenic stroke was significantly higher than in atherosclerotic and unexplained stroke group. Whereas, no statistical difference was observed in the D-dimer level between these groups ( P > 0.05). 3. The correlation between FM and NIHSS scores in the cardiogenic (r = 0.3832) and atherosclerotic (r = 0.3144) groups was statistically significant. 4. FM exhibited the highest diagnostic efficacy for cardiogenic AIS; furthermore, FM combined with the NIHSS score was more conducive to the differential diagnosis of cardiogenic and non-cardiogenic AIS. FM detection contributes to the early diagnosis of AIS, and is important for the differential diagnosis of different TOAST types of AIS. Moreover, FM combined with the NIHSS score is valuable in the differential diagnosis of cardiogenic and non-cardiogenic AIS.

Differential Diagnosis of a Hepatic Mass by 99mTc-labelled Red Cells and Octreotide Scintigraphy

2019 ◽  
Vol 97 (6) ◽  
pp. 355-357
Author(s):  
Ignacio León-Asuero-Moreno ◽  
María Cinta Calvo-Morón ◽  
Francisco Javier Garcia-Gomez ◽  
Gertrudis Sabatel-Hernández ◽  
Juan Castro-Montaño
Keyword(s):  
Differential Diagnosis ◽  
Red Cells ◽  
Hepatic Mass ◽  
Octreotide Scintigraphy

scholarly journals Petrous apex cholesterol granuloma: pictorial review of radiological considerations in diagnosis and surgical histopathology

2013 ◽  
Vol 127 (4) ◽  
pp. 339-348 ◽  
Author(s):  
M Hoa ◽  
J W House ◽  
F H Linthicum ◽  
J L Go
Keyword(s):  
Differential Diagnosis ◽  
Surgical Management ◽  
Fibrous Tissue ◽  
Tissue Reaction ◽  
Petrous Apex ◽  
Cholesterol Granuloma ◽  
Surgical Drainage ◽  
Radiological Features ◽  
Pictorial Review ◽  
Appropriate Treatment

AbstractBackground:Petrous apex cholesterol granulomas are expansile, cystic lesions containing cholesterol crystals surrounded by foreign body giant cells, fibrous tissue reaction and chronic inflammation. Appropriate treatment relies on an accurate radiological diagnosis and an understanding of the distinguishing radiological features of relevant entities in the differential diagnosis of this condition.Methods:Firstly, this paper presents a pictorial review of the relevant radiological features of petrous apex cholesterol granuloma, and highlights unique features relevant to the differential diagnosis. Secondly, it reviews the histopathological and radiological findings associated with surgical drainage of these lesions.Results:Radiological features relevant to the differential diagnosis of petrous apex cholesterol granuloma are reviewed, together with radiological and histopathological features relevant to surgical management. Following surgical management, histopathological and radiological evidence demonstrates that the patency of the surgical drainage pathway is maintained.Conclusion:Accurate diagnosis of petrous apex cholesterol granuloma is essential in order to instigate appropriate treatment. Placement of a stent in the drainage pathway may help to maintain patency and decrease the likelihood of symptomatic recurrence.

Systemic Diseases Associated with Nasal Symptoms

1987 ◽  
Vol 1 (1) ◽  
pp. 33-44 ◽  
Author(s):  
Guy A. Settipane
Keyword(s):  
Differential Diagnosis ◽  
Fungal Infections ◽  
Systemic Disease ◽  
Systemic Diseases ◽  
Proper Treatment ◽  
Csf Rhinorrhea ◽  
Nasal Symptoms ◽  
Appropriate Treatment ◽  
Life Threatening ◽  
Careful History

Many systemic diseases are associated with nasal symptoms, Rhinitis associated with asthma is probably the most common with leprosy and fungal infections being the rarest. A careful history and nasal examination in a patient with rhinitis may lead to the discovery of more significant systemic diseases. Proper treatment of systemic disease will often cure or improve the associated rhinitis. Similarly, appropriate treatment of the rhinitis/sinusitis may reduce systemic complaints such as asthma. At times, identification of the cause of rhinitis as in CSF rhinorrhea, Wegeners’ syndrome, etc., alerts one to a life-threatening entity. Thus, it is apparent that the nose is an excellent mirror of some systemic diseases and identifying and understanding the differential diagnosis of nasal symptoms may be a tremendous help in diagnosing the disease and treating the whole patient.

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