scholarly journals Oral Lesion as Unusual First Manifestation of Multiple Myeloma: Case Reports and Review of the Literature

2014 ◽  
Vol 2014 ◽  
pp. 1-7
Author(s):  
A. Romano ◽  
M. S. Marescalco ◽  
Chiara Liardo ◽  
L. Villari ◽  
C. Vetro ◽  
...  
Keyword(s):  
Multiple Myeloma ◽  
Hematological Malignancy ◽  
Case Reports ◽  
Oral Lesion ◽  
Extramedullary Plasmacytoma ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Multistage Process ◽  
Solitary Bone Plasmacytoma ◽  
Magnetic Resonance Imaging Mri

Extramedullary plasmacytoma (EMP) and solitary bone plasmacytoma (SBP) represent a disease continuum through a multistage process of cell differentiation, survival, proliferation, and dissemination, strictly related to multiple myeloma (MM), the second most common hematological malignancy. Herein, we report two cases of recurrent oral plasmacytoma progressed to MM, in which the first clinical sign of a more widespread disease was limited to the mouth. Based on our experience, we recommend a strict workup for the differential diagnosis between EMP, SBP, and MM for patients with oral plasmacytoma, including radiological exam of the skeleton, magnetic resonance imaging (MRI) of the bone, and positive emission tomography (FDG-PET). MRI and possibly PET can all be used to more sensitively detect EM plasmacytoma sites.

scholarly journals Progressive multifocal leukoencephalopathy during ixazomib-based chemotherapy

2018 ◽  
Vol 25 (1) ◽  
pp. 99 ◽  
Author(s):  
C.P. Sawicki ◽  
S.A. Climans ◽  
C.C. Hsia ◽  
J.A. Fraser
Keyword(s):  
Multiple Myeloma ◽  
Progressive Multifocal Leukoencephalopathy ◽  
Demyelinating Disease ◽  
Opportunistic Infections ◽  
Case Reports ◽  
Neurological Deficits ◽  
Resonance Imaging ◽  
Latent Form ◽  
The Central Nervous System ◽  
Magnetic Resonance Imaging Mri

Progressive multifocal leukoencephalopathy (pml) is a rare demyelinating disease of the central nervous system that most often affects immunocompromised individuals. It is caused by the reactivation of the John Cunningham virus (jcv), which is found in latent form in the majority of adults. We describe a 59-year-old man with multiple myeloma who developed severe neurological deficits during treatment with ixazomib-based chemotherapy. A diagnosis of pml was established with gadolinium-enhanced magnetic resonance imaging (mri) and by detection of jcv in the cerebrospinal fluid. Despite cessation of chemotherapy and treatment with mirtazapine, he had an inexorable neurological decline and died two months after presenting to hospital. Multiple myeloma and its treatments can predispose patients to opportunistic infections including pml. Although there have been case reports of pml in patients with multiple myeloma treated with bortezomib (a different proteosome inhibitor), this is, to our knowledge, the first documented case of pml in a patient treated with a regimen that includes ixazomib.

Penetrating abdominal aortic ulcers: case reports and review of the literature

Vascular ◽  
2011 ◽  
Vol 19 (6) ◽  
pp. 346-350 ◽  
Author(s):  
Viviane Kazan ◽  
Tahir Jamil ◽  
Rahma Beyrouti ◽  
Munier Nazzal
Keyword(s):  
Magnetic Resonance Imaging ◽  
Open Repair ◽  
Case Reports ◽  
Ct Scans ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Endovascular Techniques ◽  
Mortality And Morbidity ◽  
Abdominal Aortic ◽  
Magnetic Resonance Imaging Mri

Atherosclerotic abdominal aortic ulcers are uncommon in contrast to those of the thoracic aorta. They present with a variety of symptoms. Computed tomography (CT) scans and magnetic resonance imaging (MRI) are the methods of diagnosis. Treatment is made easier with the use of endovascular techniques, which have less mortality and morbidity than open repair. In this paper, we present three cases of penetrating aortic ulcers presenting with abdominal pain. In two of those cases, the diagnosis was made by MRI and missed by CT scan. We present a review of the literature.

Tattoo complications and magnetic resonance imaging: a comprehensive review of the literature

2020 ◽  
Vol 61 (12) ◽  
pp. 1695-1700
Author(s):  
Kasper Køhler Alsing ◽  
Helle Hjorth Johannesen ◽  
Rasmus Hvass Hansen ◽  
Jørgen Serup
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Case Reports ◽  
Clinical Signs ◽  
Full Recovery ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Comprehensive Review ◽  
Fast Onset ◽  
Magnetic Resonance Imaging Mri

Tattooed patients undergoing magnetic resonance imaging (MRI) can develop cutaneous complications during the procedure. Our aim was to review all published case reports on MRI-induced tattoo complications to identify a possible pattern. So far, 17 cases have been reported. Five (29%) of the cases were in cosmetic tattoos.  Symptoms are abrupt and painful with fast onset during MRI, sometimes requiring termination of the procedure. Clinical signs are absent or manifested as inflammation sensed as burning. No thermal skin burns have been recognized. Full recovery is fast, with no sequelae.  MRI-induced tattoo complications are uncommon. Patients with cosmetic and traditional tattoos can undergo routine MRI.

scholarly journals Imaging Findings of Plasmacytoma of Both Breasts as a Preceding Manifestation of Multiple Myeloma

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Young Mi Park
Keyword(s):  
Multiple Myeloma ◽  
Unusual Case ◽  
Extramedullary Plasmacytoma ◽  
Emission Tomography ◽  
Rare Tumor ◽  
Imaging Findings ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Positron Emission ◽  
One Year

Breast plasmacytoma is an extremely rare tumor. It can occur as a primary isolated tumor or as an extramedullary manifestation in multiple myeloma. This report describes the unusual case of a primary extramedullary plasmacytoma that progressed to multiple myeloma within 15 months in a 35-year-old woman. The patient had been initially diagnosed with a primary extramedullary plasmacytoma of the epidural soft tissue at the cervical 6-thoracic 1 spine level and the stomach. The patient had received chemotherapy and the disease had been in remission. One year later, the disease recurred, affecting both breasts, right clavicle, and orbit. Three months later, the disease had progressed to multiple myeloma. I report this case, focusing on the findings of mammography, ultrasonography, magnetic resonance imaging, and positron emission tomography of bilateral breast plasmacytoma, and provide a review of the literature.

scholarly journals Bone marrow abnormalities detected by magnetic resonance imaging as initial sign of hematologic malignancies

2018 ◽  
Author(s):  
Ida Sofie Grønningsæter ◽  
Aymen Bushra Ahmed ◽  
Nils Vetti ◽  
Silje Johansen ◽  
Øystein Bruserud ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Bone Marrow ◽  
Magnetic Resonance ◽  
Case Reports ◽  
Cell Types ◽  
Hematologic Malignancies ◽  
Resonance Imaging ◽  
Initial Sign ◽  
Magnetic Resonance Imaging Mri

The increasing use of radiological examination, especially magnetic resonance imaging (MRI), will probably increase the risk of unintended discovery of bone marrow abnormalities in patients where a hematologic disease would not be expected. In this paper we present four patients with different hematologic malignancies of nonplasma cell types. In all patients the MRI bone marrow abnormalities represent an initial presentation of the disease. These case reports illustrate the importance of a careful diagnostic follow-up without delay of patients with MRI bone marrow abnormalities, because such abnormalities can represent the first sign of both acute promyelocytic leukemia as well as other variants of acute leukemia.

scholarly journals Surgery results in low relapse and progression rates in extramedullary plasmacytoma of the head and neck: A case cohort and review of the literature

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Matevz Skerget ◽  
Tadej Dovsak ◽  
Gregor Kos ◽  
Samo Zver
Keyword(s):  
Multiple Myeloma ◽  
Local Recurrence ◽  
Head And Neck ◽  
Treatment Option ◽  
Local Control ◽  
Extramedullary Plasmacytoma ◽  
Initial Evaluation ◽  
Review Of The Literature

Extramedullary plasmacytoma of the head and neck is a rare indolent neoplasm. Radiotherapy is often the preferred treatment option with excellent local control and survival. The risk of local recurrence or transformation to multiple myeloma is 10- 30%. In our case-cohort, thorough, sensitive initial evaluation for disseminated clonal disease and the incorporation of surgery led to excellent results with no recurrences or systemic progression.

scholarly journals Focal Periphyseal Oedema: A Physiologic Finding in Paediatric Knee Pain

2021 ◽  
Author(s):  
Susana Rosa ◽  
Margarida Freitas ◽  
Sara Antunes ◽  
Rute Pereira
Keyword(s):  
Knee Pain ◽  
Case Reports ◽  
Weight Bearing ◽  
Rehabilitation Program ◽  
Joint Line ◽  
Primary Care Clinician ◽  
Male Adolescent ◽  
Resonance Imaging ◽  
Inflammatory Drugs ◽  
Magnetic Resonance Imaging Mri

Knee pain is a common reason for adolescent calls or visits to a primary care clinician. The authors present a case of an 14-year-old male adolescent with progressive bilateral nociceptive somatic knee pain. The pain was worse with weight bearing, and relieved at rest. It was located over the medial joint line. The patient was treated conservatively with nonsteroidal anti-inflammatory drugs and a rehabilitation program. Magnetic Resonance Imaging (MRI) showed bone marrow oedema, and Focal Periphyseal Oedema (FOPE) diagnosis was made. After a total of 6 months of treatment, the patient was asymptomatic. The literature is limited to a few case reports and radiologic studies describing this symptomatic physeal pathology, not reporting physical examination or treatment. The goals of this case report were to elucidate physicians of this condition, a newly reported cause of knee pain in adolescent, and to elicit the importance of a patient-tailored rehabilitation program in the treatment of this finding. FOPE is a clinical entity that should not be ignored and must be treated for the patient’s comfort. It is a self-limited condition and has an excellent prognosis.

scholarly journals Colon Adenocarcinoma during Pregnancy: A Case Report and Review of the Literature

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Paolo Petruzzelli ◽  
Roberto Zizzo ◽  
Elisabetta Tavassoli ◽  
Miriam Sutera ◽  
Michela Chiadò Fiorio Tin ◽  
...  
Keyword(s):  
Clinical Course ◽  
Colon Adenocarcinoma ◽  
Male Infant ◽  
Exploratory Laparotomy ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Local Hospital ◽  
Descending Colon ◽  
Magnetic Resonance Imaging Mri

Colorectal cancer (CRC) during pregnancy presents an estimated incidence of 1 : 13,000, and it is associated with diagnostic and therapeutic challenges. Here, we present the case of a 38-year-old woman, 25 weeks and 5 days pregnant, who was transferred to our Obstetrics and Gynecology Department from a local hospital with the diagnosis of intestinal obstruction. Magnetic Resonance Imaging (MRI) showed marked distension with hydroaerial levels of the enterocolic loops upstream of a concentric parietal thickening of the descending colon, stenosing, extended longitudinally for about 4 cm. An exploratory laparotomy was performed with resection of the colon splenic flexure and mechanical end-terminal anastomosis. Histological examination of the operating piece highlighted the presence of moderately differentiated (G2) colon adenocarcinoma (stage pT3N1b). The operation was followed by a single course of oxaliplatin and 5-FU plus leukovorin. The patient had a vaginal delivery at 37   weeks + 2 days of gestational age, following induction of labor and giving birth to a male infant whose weight was 2670 gr with apgar 9/9. We underline the pivotal role of attention to unspecific symptoms, early diagnosis, and active treatment in changing the clinical course of CRC.

Infiltration into soils, with particular reference to its visualization and measurement by magnetic resonance imaging (MRI)

1998 ◽  
Vol 22 (2) ◽  
pp. 135-165 ◽  
Author(s):  
M. H.G. Amin ◽  
L. D. Hall ◽  
R. J. Chorley ◽  
K. S. Richards
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Temporal Distribution ◽  
Water Infiltration ◽  
Spatial And Temporal Distribution ◽  
Review Of The Literature ◽  
Resonance Imaging ◽  
Macropore Flow ◽  
Wide Range ◽  
Magnetic Resonance Imaging Mri

This article draws attention to the potential of magnetic resonance imaging (MRI) for studies of patterns and mechanisms of water infiltration into soils, and stresses the vitally important need for collaboration between hydrologists, soil physicists and MRI experts. A brief introduction of the principles of MRI is given. This is followed by a review of the literature relating to nonpreferential infiltration, preferential infiltration exhibiting fingering and preferential infiltration involving a wide range of macropore flow. These differing degrees of complexity of infiltration dynamics require the employment of noninvasive and nondestructive techniques for their detailed investigation. Finally, an overview of applications of MRI to the detection of the spatial and temporal distribution of soil moisture and its changes is given. General conclusions are drawn from previous and current research, and the potential of the application of MRI to infiltration studies is summarized.

Sign in / Sign up

Export Citation Format

Share Document