scholarly journals Primary Malignant Melanoma of Maxilla: Report of a Case with Discussion

2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
G. Shirisha Rani ◽  
T. Vinay Kumar ◽  
Balaram Kolasani ◽  
Md Rezwana Begum ◽  
Anu Priya Srinivasan
Keyword(s):  
Surgical Treatment ◽  
Malignant Melanoma ◽  
Oral Cavity ◽  
Head And Neck ◽  
Cutaneous Melanoma ◽  
Dental Clinic ◽  
Oral Melanoma ◽  
Pigmented Lesion ◽  
Oral Malignant Melanoma ◽  
Rule Out

Primary oral malignant melanoma, very rare neoplasm of melanocytic origin, usually presents as a bluish black to tan-brown colored lesion Which is accounting for 0.2 to 8% of all melanomas, 1.6% of all head and neck malignancies, and 0.5% of all oral neoplasia. In general, the prognosis of oral melanoma is poor and worse than that of cutaneous melanoma. Here a case of oral malignant melanoma is presented, which was undetected during the first visit to a dental clinic. When a simple oral surgical treatment was carried out in that region, it resulted in the appearance of a massive pigmented lesion which was histopathologically diagnosed as malignant melanoma. This paper is presented to reemphasize the fact that any pigmented lesion in the oral cavity should be viewed with suspicion and proper investigation (biopsy) should be carried out to rule out any untoward experiences later.

scholarly journals Primary Oral Malignant Melanoma: Two Case Reports and Review of Literature

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Neeraj Sharma
Keyword(s):  
Malignant Melanoma ◽  
Early Detection ◽  
Oral Cavity ◽  
Tumor Size ◽  
Malignant Tumors ◽  
Case Reports ◽  
Review Of Literature ◽  
Oral Region ◽  
Rare Neoplasm ◽  
Oral Malignant Melanoma

Primary malignant melanoma of the oral cavity is a rare neoplasm. The tumors tend to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. The survival of patients with mucosal melanomas is less than for those with cutaneous melanomas. Tumor size and metastases are related to the prognosis of the disease. Early detection, therefore, is important.

scholarly journals Massive chondrogenic osteosarcoma of the maxilla: A case report

1970 ◽  
Vol 10 (1) ◽  
pp. 57-59
Author(s):  
M Irfan ◽  
RR Ramli ◽  
AK Shamim ◽  
A Pohchi
Keyword(s):  
Case Report ◽  
Surgical Treatment ◽  
Oral Cavity ◽  
Head And Neck ◽  
Hard Palate ◽  
Medical Science ◽  
Bone Cancer ◽  
Wide Margin ◽  
Primary Bone

Although osteosarcoma is the most common primary bone cancer, the incidence in head and neck bony structures is extremely low. As the surgical treatment requires a wide margin excision, the operation usually will be very challenging especially if it involves midline structures. We report a case of a young gentleman who had a bony growth over the epicenter of the hard palate which rapidly occupies the whole oral cavity within 6 months duration. The outline of management is discussed. Keywords: Osteosarcoma; hard palate. DOI: 10.3329/bjms.v10i1.7322 Bangladesh Journal of Medical Science Vol.10 No.1 Jan 2010 pp.57-59

scholarly journals Mucosal Melanoma in the Head and Neck Region: Different Clinical Features and Same Outcome to Cutaneous Melanoma

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Faruk Tas ◽  
Serkan Keskin
Keyword(s):  
Overall Survival ◽  
Oral Cavity ◽  
Head And Neck ◽  
Clinical Features ◽  
Cutaneous Melanoma ◽  
Regional Lymph Node ◽  
Survival Rates ◽  
Mucosal Melanoma ◽  
Significant Prognostic Factor ◽  
Overall Survival Rates

Mucosal melanoma (MM) in the head and neck (H&N) is relatively rare and behaves in distinct pattern from cutaneous melanoma (CM). We performed this study to define clinical characteristics and outcomes of patients and emphasize MM differences from CM. Forty-one patients with MM located in H&N were assessed. 94 CM patients originated from H&N region were also used for comparison. Patients had oral cavity (51%) and sinonasal location (49%).The median age was 60 years and gender distribution was equal. Thirty-two (78%) patients had localized stage, four (10%) patients had regional lymph node metastasis, and five (12%) patients had distant metastasis. The 1- and 5-year overall survival rates were 81% and 58%, respectively. Outcomes were similar between sinonasal and oral cavity patients (). Advanced disease was the significant prognostic factor for outcome (). MM patients are older () and more diagnosed as a localized disease patients at presentation than those with CM (). Overall survival rates were identical in patients with MM and CM (). In conclusion, despite different clinical features, outcome was identical in patients with MM and CM located in the H&N region.

scholarly journals SURGICAL TREATMENT OF HEAD AND NECK CUTANEOUS MELANOMA: A MODERN APPROACH TO THE PROBLEM

2016 ◽  
Vol 6 (4) ◽  
pp. 19-25
Author(s):  
M. B. Pak ◽  
A. M. Mudunov ◽  
L. V. Demidov ◽  
R. I. Azizyan ◽  
V. Zh. Brzhezovskiy ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Head And Neck ◽  
Cutaneous Melanoma ◽  
Modern Approach

scholarly journals Non-surgical treatment of canine oral malignant melanoma: A case study of the application of complementary alternative medicine

2014 ◽  
Vol 7 (6) ◽  
pp. 1829-1830 ◽  
Author(s):  
HIROYASU ITOH ◽  
TOSHIYUKI MUKAIYAMA ◽  
TAKAHIRO GOTO ◽  
KEISHI HATA ◽  
KAZUO AZUMA ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Malignant Melanoma ◽  
Alternative Medicine ◽  
Complementary Alternative Medicine ◽  
Oral Malignant Melanoma ◽  
Non Surgical Treatment

Oral malignant melanoma (A case report and review of literature)

1986 ◽  
Vol 100 (3) ◽  
pp. 371-375 ◽  
Author(s):  
Mukhesh Sooknundun ◽  
S. K. Kacker ◽  
K. Kapila ◽  
K. Verma ◽  
P. Narayan
Keyword(s):  
Malignant Melanoma ◽  
Needle Aspiration ◽  
Review Of Literature ◽  
Breast Metastasis ◽  
Aspiration Cytology ◽  
Cervical Lymph Nodes ◽  
Oral Melanoma ◽  
Rapid Spread ◽  
Oral Malignant Melanoma ◽  
Needle Aspiration Cytology

AbstractOral malignant melanoma is rare and has a poor prognosis. We report a case of melanoma of the lower alveolus with rapid spread to the cervical lymph nodes and breast. Metastasis was diagnosed by fine needle aspiration cytology. The literature on oral melanoma is also reviewed.

Positive Margins in Cutaneous Melanoma of the Head and Neck: Implications for Timing of Reconstruction

2020 ◽  
pp. 019459982096917
Author(s):  
Arya W. Namin ◽  
Lauren Welby ◽  
Austin T. Baker ◽  
Laura M. Dooley
Keyword(s):  
Surgical Treatment ◽  
Head And Neck ◽  
Cutaneous Melanoma ◽  
Spindle Cell ◽  
National Cancer Database ◽  
Clinicopathologic Features ◽  
Lentigo Maligna ◽  
Positive Margins ◽  
Lentigo Maligna Melanoma ◽  
The Face

Objective The aim of this study is to identify clinicopathologic features associated with positive margins after surgical treatment of cutaneous melanoma of the head and neck (CMHN). Study Design Retrospective cohort study. Setting National Cancer Database. Methods A retrospective analysis of the National Cancer Database was performed of patients diagnosed with CMHN between 2004 and 2016. Univariate and multivariate analyses examining the association of clinicopathologic features with positive margins were performed via logistic regression analysis. Results A total of 101,560 patients met inclusion criteria. The incidence of positive margins was 5.0% (5128/101,560). Patients were significantly more likely to have positive margins with the following: increasing age ( P < .001; odds ratio [OR], 1.028; 95% CI, 1.026-1.031), the lip subsite ( P < .001; OR, 1.664; 95% CI, 1.286-2.154), the eyelid subsite ( P < .001; OR, 2.380; 95% CI, 1.996-2.838), the face subsite ( P < .001; OR, 1.215; 95% CI, 1.133-1.302), the lentigo maligna/lentigo maligna melanoma subtype ( P = .019; OR, 1.099; 95% CI, 1.016-1.188), the desmoplastic subtype ( P < .001; OR, 1.455; 95% CI, 1.261-1.680), the spindle cell subtype ( P = .006; OR, 1.276; 95% CI, 1.073-1.516), and advanced pT classification. Patients with male sex ( P < .001; OR, 0.733; 95% CI, 0.687-0.782) and without ulceration ( P < .001; OR, 0.803; 95% CI, 0.736-0.876) were significantly less likely to have positive margins. Conclusion The following have been identified as clinicopathologic features associated with positive margins after surgical treatment of CMHN: increasing age, female sex, the lip subsite, the eyelid subsite, the face subsite, ulceration, the lentigo maligna/lentigo maligna melanoma subtype, the desmoplastic subtype, the spindle cell subtype, and increasing pT classification.

scholarly journals New Trends in Cutaneous Melanoma Surgery

2019 ◽  
Vol 7 (18) ◽  
pp. 3090-3092
Author(s):  
Jacopo Scala ◽  
Aleksandra Vojvodic ◽  
Petar Vojvodic ◽  
Tatjana Vlaskovic-Jovicevic ◽  
Zorica Peric-Hajzler ◽  
...  
Keyword(s):  
Surgical Treatment ◽  
Malignant Melanoma ◽  
Sentinel Node ◽  
Surgical Management ◽  
Cutaneous Melanoma ◽  
Surgical Excision ◽  
Primary Lesion ◽  
Braf Inhibitors ◽  
Advanced Stages ◽  
Systemic Therapies

The main surgical treatment for melanoma consists in wide surgical excision of the primary lesion and the sentinel node but in recent times management of melanoma is rapidly evolving with the introduction of new systemic therapies, like BRAF inhibitors, MEK inhibitors and antibodies anti-PD-1 that show good results in controlling even advanced stages of the disease. This review aims to present data for the optimal surgical management of patients with malignant melanoma.

scholarly journals Malignant melanoma oral cavity: case report of two patients from sub-Himalayan region

2021 ◽  
Vol 7 (5) ◽  
pp. 896
Author(s):  
Jyoti Sharma ◽  
Manish Gupta ◽  
Amit Saini
Keyword(s):  
Radiation Therapy ◽  
Case Report ◽  
Malignant Melanoma ◽  
Oral Cavity ◽  
Male Patient ◽  
Radiation Treatment ◽  
Post Surgery ◽  
First Case ◽  
Pigmented Lesion ◽  
Patient Reported

<p class="abstract">Malignant melanoma of the oral cavity is an exceedingly rare tumor representing 0.2 to 8% of all melanomas. Mucosal melanomas are extremely rare and aggressive neoplasms. Patient reporting to the clinician with a pigmented lesion should raise suspicion in the first visit itself and should be further investigated so as to detect this dreaded malignancy at an earlier stage and thus managed appropriately. We presented two such rare cases who reported at our centre treated with different modalities and had different responses to treatment. In first case report 65 year old male patient diagnosed with malignant melanoma of left upper alveolus underwent multiple modalities of treatment like surgery, chemotherapy, radiation therapy but unfortunately as he defaulted post-surgery and also due to COVID-19 lockdown restrictions he was treated in various centres and finally the result was inoperable residual gigantic mass resistant to chemotherapy and radiation therapy. In second case report, 82 year old male patient reported with malignant melanoma hard palate having good response to initial chemotherapy. He was planned on hypo-fractionated radiotherapy in view of his old age but he refused radiation treatment and is on oral temozolamide and thalidomide with stable disease and good quality of life since past 6 months.</p>

The Blind Leading the Blindable

2020 ◽  
pp. 99-104
Author(s):  
Pat Croskerry
Keyword(s):  
Foreign Body ◽  
Malignant Melanoma ◽  
High Velocity ◽  
Metallic Foreign Body ◽  
Aged Patient ◽  
Tertiary Referral ◽  
Pigmented Lesion ◽  
History Of ◽  
Metallic Object ◽  
Rule Out

In this case, a middle-aged patient is referred to a tertiary referral eye hospital by an ophthalmologist for the diagnostic assessment of a pigmented lesion on the sclera of his left eye. Ostensibly, the referral is to rule out malignant melanoma. The patient has a history of a penetrating injury to his left eye from a high-velocity metallic object 10 years earlier. He is seen by multiple ophthalmologists who ruled out melanoma, concluding the lesion is a metallic foreign body exterior to the globe that did not require removal. However, an obvious and important detail is missed by all but one ophthalmologist.

Sign in / Sign up

Export Citation Format

Share Document