Psychometric Properties of the Greek Haem-A-QoL for Measuring Quality of Life in Greek Haemophilia Patients

Background and Objectives. Health Related Quality of Life (HRQoL) is an important health outcome measure in haemophilia. The aim of this study was to assess the psychometric properties of the Greek version of Haem-A-QoL, a disease-specific questionnaire for haemophiliacs.Methods. Haem-A-QoL and SF-36 were administered to 118 adult haemophilia patients. Hypothesized scale structure, internal consistency (Cronbach’sα), and test-retest reliability, as well as various types of construct validity were evaluated.Results. Scale structure of Haem-A-QoL was confirmed, with good item convergence (87%) and discrimination (80.6%) rates. Cronbach’sαwas >0.70 for all but one dimension (dealing) and test-retest reliability was significantly high. The strength of Spearman’s correlations between Haem-A-QoL and SF-36 scales ranged from 0.25 to 0.75 (P<0.01). Multiple stepwise linear regression analysis revealed that all but one Haem-A-QoL dimensions were important predictors of SF-36 scales. Known-groups comparisons yielded consistent support of the instruments’ construct validity and significant relationships were identified for age, educational level, haemophilia type, disease severity, and viral infections.Conclusion. Overall, the psychometric properties of the Greek version of Haem-A-QoL, resulting from this first time administration of the instrument to Greek adult haemophiliacs, confirmed it as a reliable and valid questionnaire for assessing haemophilia-specific HRQoL in Greece.

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Validation of the Iranian Version of the ECOS-16 Questionnaire in Patients with Osteoporotic Vertebral Fractures

Asian Spine Journal ◽

10.4184/asj.2017.11.4.586 ◽

2017 ◽

Vol 11 (4) ◽

pp. 586-593

Author(s):

Parisa Azimi ◽

Taravat Yazdanian ◽

Ali Montazeri

Keyword(s):

Quality Of Life ◽

Psychometric Properties ◽

Vertebral Fractures ◽

World Health ◽

Life Questionnaire ◽

Retest Reliability ◽

Osteoporotic Vertebral Fractures ◽

Sf 36 ◽

Test Retest Reliability

<sec><title>Study Design</title>Prospective clinical study.</sec><sec><title>Purpose</title>To translate and validate the Quality of Life Questionnaire of the European Foundation for Osteoporosis (ECOS-16) in patients with osteoporotic vertebral fractures in Iran.</sec><sec><title>Overview of Literature</title>It is important to assess the psychometric properties of instruments measuring patient-reported outcomes.</sec><sec><title>Methods</title>The translation was performed using the backward-forward translation method. The final version was generated by consensus among the translators. Every woman who had a T-score of <−2.5 completed ECOS-16. Patients were divided into two study groups according to the World Health Organization's criteria: those with at least one vertebral fracture (surgery group) and those with no fractures (control group). They were asked to respond to the questionnaire at three points in time: preoperative and twice within 1-week interval after surgery assessments (6-month follow-up). The 36-item short-form health survey (SF-36) also was completed. The psychometric properties of the questionnaire were assessed using internal consistency, test-retest reliability, convergent validity, discriminant validity, and responsiveness.</sec><sec><title>Results</title>Of 137 recruited women, 39 underwent surgery and 98 did not. Analysis of the ECOS-16 scales showed an appropriate reliability with Cronbach's alpha of >0.70 for all scales. Test-retest reliability as indicated by intraclass correlation coefficient was found to be 0.85 (0.68–0.91). Additionally, the correlation of each item with its hypothesized domain of the ECOS-16 showed acceptable results, suggesting that the items had a substantial relationship with their own domains. Further analysis also indicated that the questionnaire was responsive to change (effect size, 0.85; standardized response mean, 0.93) (<italic>p</italic><0.001). Significant correlations existed between scores of similar subscales of ECOS-16 and SF-36 (<italic>p</italic><0.001).</sec><sec><title>Conclusions</title>ECOS-16 is an acceptable, reliable, valid, and responsive measure to assess the quality of life in patients with osteoporotic vertebral fractures.</sec>

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Reliability and Validity of the Greek QLQ-C30 and QLQ-MY20 for Measuring Quality of Life in Patients with Multiple Myeloma

The Scientific World JOURNAL ◽

10.1100/2012/842867 ◽

2012 ◽

Vol 2012 ◽

pp. 1-8 ◽

Cited By ~ 9

Author(s):

Nick Kontodimopoulos ◽

Alexandros Samartzis ◽

Angelos A. Papadopoulos ◽

Dimitris Niakas

Keyword(s):

Quality Of Life ◽

Construct Validity ◽

Psychometric Properties ◽

Reliability And Validity ◽

Internal Consistency Reliability ◽

Scale Structure ◽

Sf 36 ◽

Related Quality ◽

Eortc Qlq

Objectives. The aim of this study was to assess the psychometric properties of the Greek EORTC QLQ-C30 and QLQ-MY20 instruments.Method. A sample of myeloma patients (N=89) from two tertiary hospitals were surveyed with the QLQ-C30, QLQ-MY20 and various demographic and disease related questions. The previously validated Greek SF-36 instrument was used as a “gold standard” for health-related quality of life (HRQoL) comparisons. Hypothesized scale structure, internal consistency reliability (Cronbach's alpha) and various forms of construct validity (convergent, discriminative, concurrent and known-groups) were assessed.Results. Multitrait scaling confirmed scale structure of the QLQ-C30 and QLQ-MY20, with good item convergence (96% and 72%) and discrimination (78% and 58%) rates. Cronbach'sαwas >0.70 for all but one scale (cognitive functioning). Spearman's correlations between similar QLQ-C30 and SF-36 scales ranged between 0.35–0.80 (P<0.001). Expected interscale correlations and known-groups comparisons supported construct validity. QLQ-MY20 scales showed comparatively lower correlations with QLQ-C30 functional scales, and higher correlations with conceptually related symptom scales.Conclusions. The observed psychometric properties of the two instruments imply suitability for assessing myeloma HRQoL in Greece. Future studies should focus on generalizability of the results, as well as on specific issues such as longitudinal validity and responsiveness.

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Determining the psychometric properties of a novel questionnaire to measure “preparedness for the future” (Prep FQ)

Health and Quality of Life Outcomes ◽

10.1186/s12955-021-01759-z ◽

2021 ◽

Vol 19 (1) ◽

Author(s):

Daren K. Heyland ◽

J. Paige Pope ◽

Xuran Jiang ◽

Andrew G. Day

Keyword(s):

Quality Of Life ◽

Construct Validity ◽

Health Behaviors ◽

Psychometric Properties ◽

Well Being ◽

High Quality ◽

The Future ◽

Quality Of Death ◽

Test Retest Reliability

Abstract Background People are living longer than ever before. However, with living longer comes increased problems that negatively impact on quality of life and the quality of death. Tools are needed to help individuals assess whether they are practicing the best attitudes and behaviors that are associated with a future long life, high quality of life, high quality of death and a satisfying post-death legacy. The purpose of paper is to describe the process we used to develop a novel questionnaire (“Preparedness for the Future Questionnaire™ or Prep FQ”) and to define its psychometric properties. Methods Using a multi-step development procedure, items were generated, for the new questionnaire after which the psychometric properties were tested with a heterogeneous sample of 502 Canadians. Using an online polling panel, respondents were asked to complete demographic questions as well as the Prep-FQ, Global Rating of Life Satisfaction, the Keyes Psychological Well-Being scale and the Short-Form 12. Results The final version of the questionnaire contains 34 items in 8 distinct domains (“Medico-legal”, “Social”, “Psychological Well-being”, “Planning”, “Enrichment”, “Positive Health Behaviors”, “Negative Health Behaviors”, and “Late-life Planning”). We observed minimum missing data and good usage of all response options. The average overall Prep FQ score is 51.2 (SD = 13.3). The Cronbach alphas assessing internal reliability for the Prep FQ domains ranged from 0.33 to 0.88. The intra-class correlation coefficient (ICC) used to assess the test–retest reliability had an overall score of 0.87. For the purposes of establishing construct validity, all the pre-specified relationships between Prep FQ and the other questionnaires were met. Conclusion Analyses of this novel measure offered support for its face validity, construct validity, test–retest reliability, and internal consistency. With the development of this useful and valid scale, future research can utilize this measure to engage people in the process of comprehensively assessing and improving their state of preparedness for the future, tracking their progress along the way. Ultimately, this program of research aims to improve the quality and quantity of peoples live by helping them ‘think ahead’ and ‘plan ahead’ on the aspects of their daily life that matter to their future.

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Measuring Patient-Reported Health-Related Quality of Life in Velopharyngeal Insufficiency: Reliability and Validity of the Brazilian Portuguese Version of the VELO Instrument

The Cleft Palate-Craniofacial Journal ◽

10.1177/1055665619846763 ◽

2019 ◽

Vol 56 (9) ◽

pp. 1195-1205 ◽

Cited By ~ 2

Author(s):

Rafael Denadai ◽

Cassio Eduardo Raposo-Amaral ◽

Anelise Sabbag ◽

Rafael Andrade Ribeiro ◽

Celso Luiz Buzzo ◽

...

Keyword(s):

Quality Of Life ◽

Construct Validity ◽

Internal Consistency ◽

Reliability And Validity ◽

Brazilian Portuguese ◽

Velopharyngeal Insufficiency ◽

Retest Reliability ◽

Related Quality ◽

Test Retest Reliability

Objective: To test the Brazilian Portuguese velopharyngeal insufficiency (VPI) Effects on Life Outcome (VELO) instrument for reliability and validity. Design: Cross-sectional methodological study. Setting: Tertiary craniofacial medical center. Participants: Participants with VPI (VPI group, n = 60), with cleft and without VPI (no VPI/cleft group, n = 60), and with no cleft nor VPI (no VPI/no cleft group, n = 60) and their parents (n = 180). Interventions: All patients with VPI 8+ years old and their parents completed the Brazilian–Portuguese VELO instrument and other questionnaires (Pediatric Quality of Life Inventory4.0, PedsQL4.0; Pediatric Voice-Related Quality of Life, PVRQOL; and Intelligibility in Context Scale, ICS) at baseline; patients with VPI and their parents completed the VELO instrument again 2 weeks later. Main Outcome Measures: The VELO instrument was tested for internal consistency, test–retest reliability, discriminant validity (participants with VPI against participants with no VPI), concurrent validity against other questionnaires, criterion validity against hypernasality severity, and construct validity against nasal air emission and overall velopharyngeal competence (speech construct) and velopharyngeal gap (anatomic construct). Results: The VELO had excellent internal consistency (Cronbach α 0.99 for parents and 0.98 for participants with VPI) and test–retest reliability (all intraclass correlation coefficient > 0.87). The VELO discriminated well between VPI group and unaffected groups (all P < .05). The VELO was significantly correlated with the PedsQL4.0, PVRQOL, and ICS (– r > 0.75; P < .001). The VELO met criterion validity, speech construct validity, and anatomic construct validity ( r > 0.7; P < .001). Conclusions: The Brazilian-Portuguese VELO instrument demonstrated reliability (internal consistency and test–retest) and validity (discriminant, concurrent, criterion, and construct).

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Penilaian Properti Psikometrik Instrumen Kualitas Hidup (HRQol) pada Populasi Umum: Tinjauan Sistematik

JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) ◽

10.22146/jmpf.41911 ◽

2019 ◽

Vol 9 (2) ◽

Author(s):

Restu Nur Hasanah Haris ◽

Rahmat Makmur ◽

Tri Murti Andayani ◽

Susi Ari Kristina

Keyword(s):

Quality Of Life ◽

General Population ◽

Construct Validity ◽

Psychometric Properties ◽

Short Form ◽

Internal Consistency Reliability ◽

Ceiling Effect ◽

Validity And Reliability ◽

Sf 36

Quality of life (HRQoL) is a measure of a person's health in physical, spiritual, and emotional, and role functions in the society. Measurement of quality of life (HRQoL) is an important thing to understand and evaluate. Measurements are carried out not only on patients but also on the general population with the use of specific or generic instruments. The instrument used requires a psychometric properties test to ensure its validity and reliability. This article aims to conduct a systematic review of the psychometric properties of quality of life (HRQoL) instruments in the general population. Articles were collected in December 1st to 5th, 2018, from Pubmed and Google Scholar. The assessment was carried out using the checklist properties according to the cohen criteria and included the content validity, construct validity, internal consistency reliability, test-retest, ceiling effect and the level of credibility of the instruments. Among 80 articles obtained there were 24 articles that fulfilled the inclusion criteria. Short Form-36 (SF-36) instrument is the most widely used instrument in measuring the quality of life in the general population (26.6%). Some instruments have not been tested according to the criteria, while almost all instruments show a good level of validation of construct validity using convergent and discriminat validity with cronbach alpha values > 0.7. Test-retest reliability provides a good correlation. Some instruments show a ceiling effect. According to the assessment, the SF-36, SF-6D, EQ-5D, SF-12 and PedsQoL instruments are considered as established instruments. Further validation testing is needed to provide and support the measurement of subsequent quality of life (HRQoL) instruments.

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The Arabic LupusPRO: A Cross-Cultural Validation of a Disease-Specific Patient-Reported Outcome Tool for Quality of Life in Lupus Patients

Lupus ◽

10.1177/0961203320953482 ◽

2020 ◽

Vol 29 (13) ◽

pp. 1727-1735

Author(s):

Nourhan Elameen Elkaraly ◽

Samah Ismail Nasef ◽

Aziza Sayed Omar ◽

Ahmed Mahmoud Fouad ◽

Meenakshi Jolly ◽

...

Keyword(s):

Quality Of Life ◽

Systemic Lupus Erythematosus ◽

Lupus Erythematosus ◽

Arabic Version ◽

Systemic Lupus ◽

Retest Reliability ◽

Sf 36 ◽

Patient Reported ◽

Test Retest Reliability

Objective To translate and cross-culturally adapt the Arabic version of LupusPRO v.1.8 and to test its reliability and validity. Methods LupusPRO was translated into the Arabic language following a standard procedure with forward-backward translation and was tested in patients with systemic lupus erythematosus (SLE) before use. The Arabic version was administered to 107 Egyptian SLE patients, along with a validated Arabic version of RAND 36-Item Health Survey 1.0 (SF-36). The internal consistency and test-retest reliability were determined. Validity was assessed by correlating LupusPRO scores with SF-36, Safety of Estrogens in Lupus Erythematosus National Assessment–Systemic Lupus Erythematosus Disease Activity Index (SELENA-SLEDAI) and Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI). The conceptual framework of the Arabic LupusPRO was evaluated using confirmatory factor analysis (CFA). Results Among the 107 SLE patients, 95% were women with a median (range) age of 32 (18-55) years, median (range) SELENA-SLEDAI of 6 (0-23) and median (range) SDI of 0 (0-6). The Cronbach's alpha for the Arabic LupusPRO ranged from 0.71 to 0.98, except for the social support domain (0.65). Test-retest reliability ranged from 0.95 to 0.99. Convergent validity with corresponding domains of SF 36 was satisfactory. For criterion validity, there was a weak but significant correlation between several LupusPRO domains with SELENA-SLEDAI. CFA showed a good model fit. Conclusion The Arabic version of LupusPRO v1.8 is a reliable and valid tool for measuring quality of life among Arabic speaking SLE patients.

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Cultural adaptation and validation of the Norwegian version of the swallowing quality of life questionnaire (SWAL-QOL)

Health and Quality of Life Outcomes ◽

10.1186/s12955-019-1248-0 ◽

2019 ◽

Vol 17 (1) ◽

Cited By ~ 1

Author(s):

Maribeth Caya Rivelsrud ◽

Melanie Kirmess ◽

Lena Hartelius

Keyword(s):

Quality Of Life ◽

Correlation Analysis ◽

Psychometric Properties ◽

Outcome Measures ◽

Oropharyngeal Dysphagia ◽

Norwegian Version ◽

Sf 36 ◽

Symptom Frequency ◽

Test Retest Reliability

Abstract Introduction Oropharyngeal dysphagia (OD) is a disorder that can have devastating and long lasting effects on a person’s medical, mental and psychosocial well-being, thus negatively impacting quality of life. There is currently no validated dysphagia-specific quality of life instrument in Norway. This project aims to evaluate the psychometric properties of the culturally adapted Norwegian version of SWAL-QOL (Nor-SWAL-QOL). Methods The original SWAL-QOL was translated into Norwegian according the international translation guidelines. A group of 102 persons with OD and a group of 123 healthy controls were recruited to assess the validity and reliability of the Nor-SWAL-QOL. Correlation analysis of the Nor-SWAL-QOL and the Short Form 36 (SF-36) and correlation analysis of OD group and control group Nor-SWAL-QOL subscale scores were computed to determine convergent, discriminant, and known-groups validity which help comprise construct validity. Internal consistency, test-retest reliability and intraclass correlation coefficient (ICC) were computed for reliability. Results Convergent and discriminant validity was demonstrated between Nor-SWAL-QOL subscales and SF-36 domains, and distinguished between persons with and those without oropharyngeal dysphagia on all subscales and on the symptom frequency battery (p < 0.001). Additionally, the Nor-SWAL-QOL differentiated between symptom severity levels within the OD group; those requiring food and liquid modifications and those who are tube fed and not tube fed. Nor-SWAL-QOL showed good reliability with adequate internal consistency (Cronbach’s α ≥0.70), test-retest reliability (Spearman’s rho values 0.68–0.90) and ICC values (0.67–0.89) for all subscales and for the symptom frequency battery. Conclusion Access to valid and reliable dysphagia-specific QoL outcome measures for health care practitioners, dysphagia clinicians and researchers is necessary for comprehensive assessment and treatment outcome measures. The Nor-SWAL-QOL exhibits sufficient psychometric properties for implementation in the Norwegian population.

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Arabic translation and validation of the Sinus and Nasal Quality of Life Survey (SN-5) in pediatric patients with chronic rhinosinusitis

The Egyptian Journal of Otolaryngology ◽

10.1186/s43163-021-00140-7 ◽

2021 ◽

Vol 37 (1) ◽

Author(s):

Ahmed A. Ragab ◽

Zeinab A. Kasemy ◽

Ahmad M. Hamdan

Keyword(s):

Quality Of Life ◽

Construct Validity ◽

Chronic Rhinosinusitis ◽

Internal Consistency ◽

External Validity ◽

Control Groups ◽

Retest Reliability ◽

Test Retest Reliability ◽

And Control

Abstract Background This study aimed to validate the translation of the Sinus and Nasal Quality of Life Survey (SN-5) into Arabic (SN-5a) in pediatric chronic rhinosinusitis (CRS) patients. A prospective cohort randomized controlled study was conducted on 129 children with CRS and 100 age- and sex-matched healthy children. The questionnaire was translated into the Arabic language with cross-cultural adaptation. Caregivers answered the questionnaire during their first visits and after 1 week; to assess test–retest reliability and after 2 weeks of medical treatment to test the questionnaire’s ability to detect changes in patients’ symptoms. The responses of the patients and control groups were compared to assess the external validity. Results The SN-5a showed internal consistency and reliability, with Cronbach’s alpha value being 0.69. Item–item and item–total correlation analysis showed adequate construct validity with a highly significant negative correlation between the SN-5 questionnaire items and visual analog scale (VAS) (p < 0.001). There were highly significant positive correlations between items of the questionnaire in the 1st and 2nd visits at 1 week (p < 0.001). A highly significant difference between the case and control groups had been shown for all SN-5a items (p < 0.001). Two weeks after treatment, there were large changes in all the questionnaire items between the first and last visits (effect size > 0.8 for all). Conclusion The translated SN-5a exhibited adequate construct validity, internal consistency, test–retest reliability, and external validity with quite enough ability to assess the longitudinal changes of the disease.

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Cross-Cultural Adaptation and Validation of the Italian Version of the Dysphagia Handicap Index (I-DHI)

Dysphagia ◽

10.1007/s00455-021-10369-2 ◽

2021 ◽

Author(s):

Daniela Ginocchio ◽

Aurora Ninfa ◽

Nicole Pizzorni ◽

Christian Lunetta ◽

Valeria Ada Sansone ◽

...

Keyword(s):

Quality Of Life ◽

Construct Validity ◽

Intraclass Correlation ◽

Oropharyngeal Dysphagia ◽

Life Questionnaire ◽

Retest Reliability ◽

Dysphagia Handicap Index ◽

Test Retest Reliability ◽

Healthy Participants

AbstractThe Dysphagia Handicap Index (DHI) is a valid Health-related Quality of Life (HRQOL) questionnaire for patients with oropharyngeal dysphagia (OD) of heterogeneous etiologies. The study aimed at crossculturally translating and adapting the DHI into Italian (I-DHI) and analyzing I-DHI reliability, validity, and interpretability. The I-DHI was developed according to Beaton et al. 5-stage process and completed by 75 adult OD patients and 166 healthy adults. Twenty-six patients filled out the I-DHI twice, 2 weeks apart, for test–retest reliability purposes. Sixty-two patients completed the Italian-Swallowing Quality of Life Questionnaire (I-SWAL-QoL) for criterion validity analysis. Construct validity was tested comparing I-DHI scores among patients with different instrumentally assessed and self-rated OD severity, comparing patients and healthy participants and testing Spearman’s correlations among I-DHI subscales. I-DHI interpretability was assessed and normative data were generated. Participants autonomously completed the I-DHI in maximum 10 min. Reliability proved satisfactory for all I-DHI subscales (internal consistency: α > .76; test–retest reliability: intraclass correlation coefficient > .96, k = .81). Mild to moderate correlations (− .26 ≤ ρ ≤ − .72) were found between I-DHI and I-SWAL-QoL subscales. Construct validity proved satisfactory as (i) moderate to strong correlations (.51 ≤ ρ ≤ .90) were found among I-DHI subscales; (ii) patients with more severe instrumentally or self-assessed OD reported higher I-DHI scores (p < .05); and (iii) OD patients scored higher at I-DHI compared to healthy participants (p < .05). Interpretability analyses revealed a floor effect for the Emotional subscale only and higher I-DHI scores (p < .05) for healthy participants > 65 years. In conclusion, the I-DHI is a reliable and valid HRQOL tool for Italian adults with OD.

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Persian version of the brief Older People’s Quality of Life questionnaire (OPQOL-brief): the evaluation of the psychometric properties

Health and Quality of Life Outcomes ◽

10.1186/s12955-020-01586-8 ◽

2020 ◽

Vol 18 (1) ◽

Author(s):

Awat Feizi ◽

Zahra Heidari

Keyword(s):

Quality Of Life ◽

Factor Analysis ◽

Construct Validity ◽

Older People ◽

Psychometric Properties ◽

Life Questionnaire ◽

Quality Of Life Questionnaire ◽

Persian Version ◽

Test Retest Reliability

Abstract Background and objective Quality of life (QoL) is a multi-dimensional concept and its assessment is one of important themes of care for older people. Assessing QoL in older people needs specific scales. The aim of this study was to culturally adapt and investigate the psychometric properties of the Persian version of brief Older People’s Quality of Life questionnaire (OPQOL-brief) in an Iranian older population. Methods This methodological cross-sectional study was conducted among 525 Persian-speaking older people (aged 60 and over), living in Isfahan, Iran. Translation of the OPQOL-brief questionnaire was performed using forward–backward method. Test–retest reliability was evaluated through Intra Class Correlation (ICC) coefficient and internal consistency by using Cronbach’s α. Construct validity was investigated by using exploratory factor analysis (EFA), confirmatory factor analysis (CFA), and Latent class analysis (LCA). Criterion, convergent and discriminant validities were also assessed. Results Persian version of the OPQOL-brief showed good test–retest reliability (ICC = 0.842, 95% CI = 0.73–0.91; P < 0.001). Persian OPQOL-brief scale demonstrated high internal consistency (Cronbach’s α = 0.83). It showed good discriminant validity and differentiated old patients from healthy older individuals (P < 0.001). Construct validity based on EFA led to extraction of three dimensions (“socioeconomic”, “emotional”, and “physical” well-being) and the CFA confirmed the adequacy of extracted construct from EFA (CFI = 0.909, PCFI = 0.52, PNFI = 0.5, CMIN/DF = 3.012, and RMSEA = 0.08). LCA classified participants into three classes in terms of QoL level (low (16%), middle (67%), and high (17%)). Criterion validity and convergent validity revealed significant positive correlations between OPQOL-brief and physical and psychological dimensions of the SF-36. Conclusion The Persian version of the OPQOL-brief is a reliable and valid instrument for assessing QoL with applicability in a broad range of older Persian language population.

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