scholarly journals Perivascular Wall Tumor in the Brain of a Dog

2015 ◽  
Vol 2015 ◽  
pp. 1-6
Author(s):  
Margaret Cohn-Urbach ◽  
Annie Chen ◽  
Gary Haldorson ◽  
Stephanie Thomovsky

A 9-year-old spayed female German shepherd mixed-breed dog presented for seizures. Magnetic resonance imaging revealed an irregularly marginated intraparenchymal cerebral mass. Microscopic examination of brain tissue collected postmortem demonstrated perivascular whorling and interwoven bundles of spindle-shaped cells. On immunohistochemistry, the tumor cells tested positive for vimentin and negative for factor VIII-related antigen, CD18, CD45, CD3, CD20, GFAP, S-100, and desmin. Immunohistochemistry results, in combination with histopathologic morphology, were suggestive of a perivascular wall tumor. To the authors’ knowledge, this is the first case report to utilize both histopathology and immunohistochemistry to describe a perivascular wall tumor in the brain of a dog.

2020 ◽  
Vol 18 (1) ◽  
Author(s):  
Rauf P ◽  
Aidil MN ◽  
Chan KH ◽  
Saufi A ◽  
Fadli M

Cerebral ependymal cyst is a rare benign neuroepithelial cyst. We report a case of cerebral ependymal cyst in a 62-year-old lady who presented with status epilepticus. She gave history of progressive right occipital headache over a year. Magnetic Resonance Imaging of the brain showed a large occipital cyst. She underwent a right craniotomy, deroofing of the cyst and insertion of Ommaya catheter. The clinicopathological aspects of the cyst are discussed.


2021 ◽  
Vol 2 (5) ◽  
Author(s):  
Gibson O. Anugwom ◽  
Alexsandra Urhi ◽  
David O. Otuada ◽  
Funso Oladunjoye ◽  
Arthur Dilibe ◽  
...  

Temporal lobe epilepsy is a neurological disorder of an unprovoked type of focal (partial) epilepsy that begins in the temporal lobe of the brain. Patients with this condition are often misdiagnosed due to similarities in presentation to other conditions. In this case report, we presented a 34-year-old male, who had symptoms of hallucination, anxiety, and depression which can be seen in patients with temporal lobe epilepsy. Due overlap in symptoms, he was misdiagnosed to have schizophrenia. Following subsequent review of his medical history and findings seen in his laboratory work and imaging studies, it was determined that his symptoms were caused by seizures originating from an atrophic lesion in his hippocampus found on magnetic resonance imaging of his temporal lobe.


1992 ◽  
Vol 15 (2) ◽  
pp. 123-124
Author(s):  
Masayuki Maeda ◽  
Yasutaka Kawamura ◽  
Tatsurou Tsuchida ◽  
Yasushi Ishii ◽  
Masakatsu Sudou

2012 ◽  
Vol 2012 ◽  
pp. 1-4
Author(s):  
Afshin Mohammadi ◽  
Abbas Hedayati Asl ◽  
Mohammad Ghasemi-Rad ◽  
Farahnaz Noroozinia

Introduction. Enchondroma protuberans is an extremely rare benign cartilaginous bone tumor. We report the first case report of enchondroma protuberans in the forearm.Presentation of Case. We report a case of enchondroma protuberans originating in the left ulnar bone of a young woman. A 20-year-old female referred to our hospital complaining of progressive sustained left forearm pain with a radiation to fourth and fifth finger. Conventional radiography revealed a well-defined eccentric osteolytic lesion in the distal diaphysis of ulna with expansion of overlying cortex (without calcification). Magnetic resonance imaging showed a well-defined ovoid intramedullary lesion, which was exophytically protruding from medial surface of left ulnar bone. Histopathology confirmed the diagnosis.Discussion. Enchondroma protuberans typically present as a well-defined intramedullary osteolytic lesion that may be accompanied by a fine matricidal calcification. The connection between the intramedullary portion and the exophytic protrusion can be seen well by magnetic resonance imaging.Conclusion. Enchondroma protuberans should be considered in the differential diagnosis of osteochondroma, enchondroma, and periosteal chondroid tumors.


2017 ◽  
Vol 62 (No. 11) ◽  
pp. 604-613
Author(s):  
BT Kang ◽  
D. An ◽  
HW Kim ◽  
Y. Jin ◽  
YD Son ◽  
...  

An eight-year-old, intact male Rottweiler dog was presented due to anorexia, lethargy, ataxia and imbalance. Cerebellar and thyroid masses were identified using 0.3T magnetic resonance imaging. The <sup>18</sup>F-fluorodeoxyglucose uptakes of the masses were elevated on positron emission tomography and 7 T-magnetic resonance imaging fusion imaging. At 113 days after the initial presentation, new nodular lesions were observed in the skin, liver and spleen. Histopathology revealed multiple lesions of disseminated histiocytic sarcoma in the cerebellum, liver, spleen and skin, whereas the thyroid lesions were diagnosed as mixed medullary-follicular thyroid carcinoma. The primary site of the disseminated histiocytic sarcoma was found to be in the cerebellum. To our knowledge, this is the first case report to describe the imaging and histopathological findings of extracranial metastasis of a primary intracranial histiocytic sarcoma in a dog.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Zhijie Lv ◽  
Xiaoqi Zhang ◽  
Li Wu

Abstract Background Infliximab-induced seizures in patients with Crohn’s disease are extremely rare and the mechanism of infliximab-induced seizures is unclear. Case presentation A 60-year-old woman with Crohn’s disease experienced infliximab-induced seizures, diagnosed on normal magnetic resonance imaging of the brain. Moreover, the rechallenge with infliximab was positive. Conclusions Neurological assessment and tight clinical monitoring before and during therapy with infliximab should be performed in patients with pre-existing seizure disorders.


2018 ◽  
Vol 7 (3) ◽  
pp. 217-221
Author(s):  
E. V. Shevchenko ◽  
G. R. Ramazanov ◽  
S. S. Petrikov

Background Acute dizziness may be the only symptom of stroke. Prevalence of this disease among patients with isolated dizziness differs significantly and depends on study design, inclusion criteria and diagnostic methods. In available investigations, we did not find any prospective studies where magnetic resonance imaging, positional maneuvers, and Halmagyi-Curthoys test had been used to clarify a pattern of diseases with isolated acute dizziness and suspected stroke.Aim of study To clarify the pattern of the causes of dizziness in patients with suspected acute stroke.Material and methods We examined 160 patients admitted to N.V. Sklifosovsky Research Institute for Emergency Medicine with suspected stroke and single or underlying complaint of dizziness. All patients were examined with assessment of neurological status, Dix-Hollpike and Pagnini-McClure maneuvers, HalmagyiCurthoys test, triplex scans of brachiocephalic arteries, transthoracic echocardiography, computed tomography (CT) and magnetic resonance imaging (MRI) of the brain with magnetic field strength 1.5 T. MRI of the brain was performed in patients without evidence of stroke by CT and in patients with stroke of undetermined etiology according to the TOAST classification.Results In 16 patients (10%), the cause of dizziness was a disease of the brain: ischemic stroke (n=14 (88%)), hemorrhage (n=1 (6%)), transient ischemic attack (TIA) of posterior circulation (n=1 (6%)). In 70.6% patients (n=113), the dizziness was associated with peripheral vestibulopathy: benign paroxysmal positional vertigo (n=85 (75%)), vestibular neuritis (n=19 (17%)), Meniere’s disease (n=7 (6%)), labyrinthitis (n=2 (1,3%)). In 6.9% patients (n=11), the cause of dizziness was hypertensive encephalopathy, 1.9% of patients (n=3) had heart rhythm disturbance, 9.4% of patients (n=15) had psychogenic dizziness, 0.6% of patients (n=1) had demyelinating disease, and 0.6% of patients (n=1) had hemic hypoxia associated with iron deficiency anemia.Conclusion In 70.6% patients with acute dizziness, admitted to hospital with a suspected stroke, peripheral vestibulopathy was revealed. Only 10% of patients had a stroke as a cause of dizziness.


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