scholarly journals NovelTreponema pallidumRecombinant Antigens for Syphilis Diagnostics: Current Status and Future Prospects

2017 ◽  
Vol 2017 ◽  
pp. 1-12 ◽  
Author(s):  
Aleksey Kubanov ◽  
Anastassia Runina ◽  
Dmitry Deryabin

The recombinant protein technology considerably promoted the development of rapid and accurate treponema-specific laboratory diagnostics of syphilis infection. For the last ten years, the immunodominant recombinant inner membrane lipoproteins are proved to be sensitive and specific antigens for syphilis screening. However, the development of an enlargedT. pallidumantigen panel for diagnostics of early and late syphilis and differentiation of syphilis stages or cured syphilis remains as actual goal of multidisciplinary expertise. Current review revealed novel recombinant antigens: surface-exposed proteins, adhesins, and periplasmic and flagellar proteins, which are promising candidates for the improved syphilis serological diagnostics. The opportunities and limitations of diagnostic usage of these antigens are discussed and the criteria for selection of optimal antigens panel summarized.

1979 ◽  
Vol 19 (1) ◽  
pp. 188
Author(s):  
W. E. Gray

The infusion of new technology into the offshore industry has resulted in the introduction of many types and variations of new diving systems. In addition to conventional hyperbaric manned diving and manned submarines, these include atmospheric diving suits, tethered remotely controlled submersibles, one atmosphere diving bells with manipulators and a variety of remotely controlled subsea tools.This paper reviews the current status of such systems, describes operating experiences with typical systems, and suggests criteria for selection of preferred systems. Areas of usage include exploratory drilling, field construction and development, survey, and inspection and maintenance.


1976 ◽  
Vol 56 (4) ◽  
pp. 805-809 ◽  
Author(s):  
V. M. BENDELOW

A procedure that provides information on the suitability of barley for malting and, brewing purposes is described. Three parameters are measured: mash filtration rate, wort viscosity and wort-reducing sugar content, as maltose. Maltose is determined by an auto-analyzer method and this is a satisfactory alternative to the specific gravity procedure for the estimation of percent extract. The addition of these criteria to those already in use enables more discriminatory selection at early generations of barley-breeding programs. The technique requires only one sample extraction and 18 g of laboratory malt.


Author(s):  
L.L. Zakharova ◽  
◽  
G.A. Zhorov ◽  
V.I. Dorozhkin ◽  
◽  
...  

Negative impact on the environment as a result of economic activity of man increasingly becomes the character of combined pollution of ecotoxicants, including xenobiotics of radiation and chemical nature. In animal husbandry in ecologically unfavorable regions, sorbtion-detoxication technologies based on the complex application of bioprotective substances of different origin are used to reduce the intake and accumulation of xenobiotics, to normalize the physiological state of animals and to obtain safe products. It is necessary to observe certain principles ensuring compatibility of components, a wide range of bioprotective action, efficiency and safety at their use in developing the compositions of such sorption-detoxifying complexes. The article substantiates the criteria that should be followed in creating sorption-detoxifying complexes and presents groups of drugs with different mechanisms of action (sorbents, antioxidants, immunomodulators, adaptogens and other biologically active substances) for inclusion in the formulations of combined compositions.


Author(s):  
Desislava K. Gyurova

High-quality food composition data should be representative of national food habits and consumption patterns. They should be generated according to established standard international guidelines so that they are comparable and reliable. Well-designed tables and databases should include a good selection of food components and majority of commonly consumed foods. However, this is often not the case as many tables only include raw foods and a small number of nutrients while processed and fortified foods are lacking. The aim of this review is to focus on the importance of national food composition databases; to show the current status of the problem in Bulgaria; and priorities in the development of a new modern database; in order to attract the attention of stakeholders (government institutions, universities, research institutes, manufacturers and independent specialized laboratories).


Author(s):  
Jung-Hyun Ban ◽  
Tae-Ho Kim

The purpose of this study was to identify changes in the center of pressure during stair ascending in subjects with chronic ankle instability while different angles of foot are applied. The subjects of this study were 20 male and female adults with chronic ankle instability were selected from among the employees of D Hospital in Daegu Metropolitan City. The criteria for selection of subjects with chronic ankle instability were those who felt wobbling in the ankle joint and scored not higher than 24 points in a test using the Cumberland Ankle Instability Tool (CAIT). The subjects carried out stair ascending in neutral, toe-in and toe-out postures, respectively, and changes in the center of pressure (COP) were compared and analyzed. The results of this study, no statistically significant difference appeared in the comparison between the toe-in posture and neutral posture or between the neutral posture and the toe-out posture but medial/lateral movements of the center of pressure showed significant differences between the toe-in and toe-out postures. In addition, the total travel range and the moving range of the center of pressure, the average velocity, and the anterior/posterior movements of the center of pressure showed no statistically significant difference among all three postures. As a result, it could be seen that when adults with chronic ankle instability climb the stairs, the toe-in posture reduce the medial/lateral movements of the center of pressure thereby increasing the stability of the ankle and effectively preventing re-injuries.


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