scholarly journals Synchronous Occurrence of Primary Breast Carcinoma and Primary Colon Adenocarcinoma

2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Gurkan Yetkin ◽  
Fevzi Celayir ◽  
Ismail Ethem Akgun ◽  
Ramazan Ucak
Keyword(s):  
Adjuvant Chemotherapy ◽  
Ductal Carcinoma ◽  
Histopathological Examination ◽  
Colon Adenocarcinoma ◽  
Right Hemicolectomy ◽  
Left Breast ◽  
Lymph Node Biopsy ◽  
Hepatic Flexure ◽  
Breast Invasive Ductal Carcinoma ◽  
Primary Colon

A 65-year-old female patient presented to the emergency clinic with abdominal pain, meteorism, and intermittent rectal bleeding. Colonoscopy was performed, and a hepatic flexure tumor was detected. Histopathological examination of biopsy revealed adenocarcinoma. Thoracoabdominal CT was performed for staging, and a spiculated contour mass was found incidentally on the left breast. Mammography and ultrasonography were performed for the cause of these findings, and suspicious lesions of malignancy were seen in the left breast. Invasive ductal carcinoma was detected in core needle biopsy samples from lesions. In the multidisciplinary council consisting of oncologist, pathologist, radiologist, and general surgery specialist, it was decided to perform breast operation first and then colon operation, followed by adjuvant chemotherapy. In the first operation, left total mastectomy and sentinel lymph node biopsy were performed. One week after her initial operation, the patient underwent right hemicolectomy. After operations, the patient did not develop postoperative complications and was sent to medical oncology department for adjuvant chemotherapy.

scholarly journals Synchronous breast and colon cancer: the importance of multidisciplinary team cancer meetings

2019 ◽  
Vol 12 (12) ◽  
pp. e232680
Author(s):  
Hussain Adnan Abdulla ◽  
Raed Almarzooq ◽  
Amal Alrayes
Keyword(s):  
Colon Cancer ◽  
Multidisciplinary Team ◽  
Ductal Carcinoma ◽  
Histopathological Examination ◽  
Radical Mastectomy ◽  
Right Hemicolectomy ◽  
Left Breast ◽  
Axillary Lymph Node Metastasis ◽  
Axillary Lymph ◽  
Ascending Colon

A 58-year-old female patient presented with left breast lump. Mammography and ultrasonography were performed, which reported lesions suspicious of malignancy in the left breast and axilla. Core biopsy of the lesions revealed invasive ductal carcinoma with axillary lymph node metastasis. Staging CT scan (thorax, abdomen and pelvis) identified a coexisting neoplasm in the ascending colon. Colonoscopy was performed and the tumour in the ascending colon was biopsied. Histopathological examination revealed adenocarcinoma. In the multidisciplinary team cancer meeting, it was decided to treat the breast cancer first and then the colon cancer, followed by adjuvant chemotherapy. In the first operation, left modified radical mastectomy was performed. Two weeks after her initial operation, the patient underwent laparoscopic right hemicolectomy. Postoperatively, the patient did not develop any complications and was referred to oncology for chemotherapy.

scholarly journals Vertebral hemangioma coincident with metastasis of colon adenocarcinoma

2016 ◽  
Vol 24 (3) ◽  
pp. 506-509 ◽  
Author(s):  
Krzysztof Zapałowicz ◽  
Grażyna Bierzyńska-Macyszyn ◽  
Bartłomiej Stasiów ◽  
Aleksandra Krzan ◽  
Beata Wierzycka ◽  
...  
Keyword(s):  
Colon Cancer ◽  
Vertebral Body ◽  
Spinal Canal ◽  
Cancer Metastasis ◽  
Histopathological Examination ◽  
Colon Adenocarcinoma ◽  
Quadriceps Muscle ◽  
Right Hemicolectomy ◽  
Tissue Mass ◽  
Colon Cancer Metastasis

The authors report on colon cancer metastasis to the L-3 vertebra, which had been previously found to be involved by an asymptomatic hemangioma. A 61-year-old female patient was admitted after onset of lumbar axial pain and weakness of the right quadriceps muscle. Her medical history included colon cancer that had been diagnosed 3 years earlier and was treated via a right hemicolectomy followed by chemotherapy. Presurgical imaging revealed an asymptomatic hemangioma in the L-3 vertebral body. Computed tomography and MRI of the spine were performed after admission and revealed a hemangioma in the L-3 vertebral body as well as a soft-tissue mass protruding from the L-3 vertebral body to the spinal canal. Treatment consisted of vertebroplasty of the hemangioma, left L-3 hemilaminectomy, and removal of the pathological mass from the spinal canal and the L-3 vertebral body. Histopathological examination revealed the presence of colon cancer metastasis and a hemangioma in the same vertebra.

A case of extensive ductal carcinoma in situ and sclerosing adenosis with metastasis on sentinel lymph node

2019 ◽  
Vol 105 (6) ◽  
pp. NP63-NP66
Author(s):  
Selin Narter ◽  
Secil Hasdemir ◽  
Sahsine Tolunay ◽  
Sehsuvar Gokgoz
Keyword(s):  
Lymph Node ◽  
Sentinel Lymph Node ◽  
Ductal Carcinoma In Situ ◽  
Carcinoma In Situ ◽  
Ductal Carcinoma ◽  
Left Breast ◽  
Lymph Node Biopsy ◽  
Node Biopsy ◽  
Sclerosing Adenosis

Introduction: Sclerosing adenosis is a form of adenosis characterized by lobulocentric architecture, glandular and stromal proliferation in which the stromal component compresses and distorts the glandular structures. Atypical epithelial proliferations such as atypical lobular hyperplasia, lobular carcinoma in situ, and ductal carcinoma in situ may accompany areas of sclerosing adenosis. We present a case of ductal carcinoma in situ and sclerosing adenosis with metastatic carcinoma on sentinel lymph node. Case description: A 40-year-old woman presented with a palpable mass in her left breast. Radiologic studies showed a lesion suggesting malignancy in the left breast and atypical lymph node in the left axillary region. Left lumpectomy and sentinel lymph node biopsy was performed. Histopathologic examination revealed lobulocentric lesions with glandular proliferation and hyalinizing stroma in between. Foci of high-grade cribriform and solid type ductal carcinoma in situ were observed. Sentinel lymph node biopsy showed micrometastasis in one lymph node section. Based on these findings, the patient was diagnosed with high-grade ductal carcinoma in situ with sclerosing adenosis. However, the presence of micrometastasis in the lymph node suggested occult invasion that we were not able to detect. Conclusion: Ductal carcinoma in situ with sclerosing adenosis can mimic invasive carcinoma both radiologically and histologically. It should be kept in mind that there may be occult invasive carcinoma in patients with ductal carcinoma in situ whether the lesion is accompanied by sclerosing adenosis or not. Multiple sections and immunohistochemical studies can be of help.

scholarly journals Colon cancer in malrotated gut: A case report

2021 ◽  
pp. 386-387
Author(s):  
Arnab Gupta ◽  
Subrata Kumar Sahu ◽  
Samir Bhattacharya ◽  
Sudip Haldar
Keyword(s):  
Colon Cancer ◽  
Histopathological Examination ◽  
Incidental Finding ◽  
Vascular Anomaly ◽  
Right Hemicolectomy ◽  
Hepatic Flexure ◽  
Colon Cancers ◽  
Mesenteric Vessels ◽  
Well Differentiated

Malrotation of the gut is a rare congenital anomaly that mostly presents in the 1st month of life. Very rarely, it is found during adulthood either as an asymptomatic incidental finding or at autopsy. Presenting in adulthood with colon cancers is extremely rare. Here, we present the case of a middle-aged male patient with unexplained anemia which on investigation was found to have adenocarcinoma at the hepatic flexure of the colon. The staging computed tomography scan of the abdomen showed the growth at the hepatic flexure with malrotation of the gut. During the laparoscopic assessment, the cecum and ascending colon were found on the left side, and hence, a formal midline incision was made. Cecum was found on the left of the midline along with Ladd’s band. Extended right hemicolectomy was performed, dividing the Ladd’s band, taking care of the anomalous position of superior mesenteric vessels. The post-operative period was uneventful. Histopathological examination revealed this to be well-differentiated adenocarcinoma (pT3N1b). He thereafter received adjuvant chemotherapy and remains well after 5 years of follow-up. Presentation of malrotation of the gut in adulthood is seen in only 10–15% of cases as an incidental finding or at autopsy. Cancers in the colon in these patients are extremely rare. The treatment for colon cancer remains the same although one has to be careful about the vascular anomaly during the resection.

scholarly journals Diagnosis and treatment of chylous leakage after modified radical mastectomy for breast cancer: a case report

2021 ◽  
Vol 49 (6) ◽  
pp. 030006052110213
Author(s):  
Yingcheng Bai ◽  
Xuemei Tao ◽  
Chunhong Xu ◽  
Yanpeng Zhu
Keyword(s):  
Breast Cancer ◽  
Chest Wall ◽  
Ductal Carcinoma ◽  
Rare Complication ◽  
Radical Mastectomy ◽  
Left Breast ◽  
Modified Radical Mastectomy ◽  
Breast Invasive Ductal Carcinoma ◽  
Chylous Leakage ◽  
Meglumine Diatrizoate

The post-operative complication of chylous leakage after breast cancer is relatively rare, and few clinical studies have been published. We report a 64-year-old woman with chylous leakage following modified radical mastectomy. We describe the patient’s diagnostic and treatment process in detail. The patient was diagnosed with grade II (left) breast invasive ductal carcinoma. Post-operatively, the patient's chest wall and axilla were pressurized, and negative pressure drainage was initiated. On the fifth post-operative day, the drainage from the chest wall and axilla increased significantly, and the patient developed chylous leakage on the eighth postoperative day. We injected meglumine diatrizoate (100 mL) and elemene (10 mL) into the patient's axilla, and the chylous leakage gradually resolved 18 days post-operatively. In this report, we focus on managing a case of chylous leakage after modified radical mastectomy for breast cancer. Meglumine diatrizoate combined with elemene is a possible treatment for the management of this rare complication.

scholarly journals Metastatic Carcinoma Breast Presenting as Appendicular Abscess

2021 ◽  
Author(s):  
Meenakshi Yeola (Pate) ◽  
Kushagra Singh ◽  
Darshana Tote ◽  
Azeem Javed Aalam ◽  
Pankaj Gharde
Keyword(s):  
Adjuvant Chemotherapy ◽  
Ductal Carcinoma ◽  
Incidental Finding ◽  
Iliac Fossa ◽  
Locally Advanced ◽  
Radical Mastectomy ◽  
Left Breast ◽  
Metastatic Carcinoma ◽  
Breast Lump ◽  
High Grade Fever

Breast cancer is the most common cancer in females worldwide and presents mostly as a hard painless lump in breast. Authors report a case of a 59-year-old female who presented to emergency department with complaints of pain and lump in right iliac fossa, high grade fever with chills and rigor, multiple episodes of vomiting. She was febrile having tachycardia with normal blood pressure. Examination revealed a firm tender lump in right iliac fossa with guarding of abdomen. Incidental finding of a large left sided breast lump was noted. Radiological investigations revealed appendicular abscess. She was undertaken for emergency diagnostic laparoscopy followed by appendectomy. Surprisingly, histopathology revealed deposits of ductal carcinoma in appendix. She developed faecal fistula at incision site. On further evaluation of left breast lump it was diagnosed as locally advanced breast carcinoma. Patient was managed with neo-adjuvant chemotherapy followed by left sided Modified Radical Mastectomy (MRM) and adjuvant chemotherapy. She was on regular follow-up since then. Appendicular metastasis is one of the rare sites of metastasis of breast malignancy and presentation as appendicular abscess made the diagnosis and management challenging.

scholarly journals Adenocarcinoma of the appendix mimicking complicated appendicitis in the elderly: A report of two cases

2018 ◽  
Vol 71 (11-12) ◽  
pp. 405-408
Author(s):  
Mirjana Cuk ◽  
Radoslav Gajanin ◽  
Slavisa Djuricic ◽  
Veljko Maric ◽  
Radmil Maric ◽  
...  
Keyword(s):  
Adjuvant Chemotherapy ◽  
Acute Appendicitis ◽  
Histopathological Examination ◽  
Right Hemicolectomy ◽  
Complicated Appendicitis ◽  
Histopathological Analysis ◽  
Low Grade ◽  
Recurrent Tumor ◽  
Appendiceal Adenocarcinoma ◽  
Complicated Acute Appendicitis

Introduction. Primary appendiceal adenocarcinoma is a very rare malignancy which accounts for 0.1% of all appendectomy specimens. In both patients presented in this paper, appendectomy was performed due to suspected acute complicated appendicitis. Case Reports. The first patient, a 77-year-old man, presented with a low grade colonic-type pT3 adenocarcinoma of the appendix, diagnosed by histopathological examination of the resected appendix delivered in a fixative. A month after appendectomy, the patient underwent right hemicolectomy of a tumor at the edge of the resection. Due to a cardiovascular disease, adjuvant chemotherapy was not indicated. The second patient, a 74-year-old female, presented with a low grade mucinous adenocarcinoma of the appendix with subserous infiltration, diagnosed by histopathological analysis of the resected appendix. Eight months after appendectomy, the patient developed a recurrent tumor in the cecal area. After radical surgical excision of the recurrent tumor, the patient received adjuvant chemotherapy. Both patients had a 5-year survival without relapse. Conclusion. Preoperative diagnosis of appendiceal adenocarcinoma is a challenge due to overlapping symptoms of complicated acute appendicitis. Our results suggest that in elderly patients with symptoms of complicated acute appendicitis, appendectomy should be done with intraoperative histopathological frozen section consultation. In advanced stages of adenocarcinoma, right hemicolectomy is a better choice than appendectomy.

scholarly journals Male Triple Negative Axillary Accessory Breast Cancer, a Case Report

2021 ◽  
Author(s):  
Chao li ◽  
Biao Qian
Keyword(s):  
Breast Cancer ◽  
Adjuvant Chemotherapy ◽  
Lymph Nodes ◽  
Triple Negative ◽  
Ductal Carcinoma ◽  
Axillary Lymph Nodes ◽  
Axillary Lymph ◽  
Ki 67 ◽  
Breast Invasive Ductal Carcinoma ◽  
Accessory Breast

Abstract Background: Breast cancer is the most common malignancy among women worldwide. In men, cases of breast cancer are few and accounts for less than 1% of all cases of breast cancer. Majority of male breast cancer is hormone receptor-positive. The incidence of male axillary accessory breast cancer derived from axillary accessory breast is very low. Here we report a case of male triple negative axillary accessory breast cancer.Case presentation: We present a case of a male triple negative axillary accessory breast cancer in a 67-year-old man that progressively increased in size through a period of 1 year. We performed right accessory breast resection and right axillary lymph nodes dissection. Postoperative pathological analysis revealed right accessory breast invasive ductal carcinoma with apocrine metaplasia. The tumor size was 3.5 * 3.3cm. In addition, 5 metastatic lymph nodes were seen in 27 axillary lymph nodes. Immunohistochemistry showed ER (-), PR (-), Ki-67 30%, HER2 (2 +), GATA-3 (+), GCDFP-15(+), and AR (+). Fish test obtained a negative result. The patient was treated with adjuvant chemotherapy and radiotherapy.Conclusion: Male triple negative axillary accessory breast cancer is rare. Treatment of male triple negative axillary accessory breast cancer is similar to that of women patients. Most patients undergo surgery and adjuvant chemotherapy.

scholarly journals Cutaneous Metastasis in the Setting of Both Colon and Breast Primary Malignancies

2020 ◽  
Vol 2020 ◽  
pp. 1-4
Author(s):  
Mary Junak ◽  
Hunter Jecius ◽  
Jennifer Erdrich ◽  
Shiro Kikuchi
Keyword(s):  
Ductal Carcinoma ◽  
Case Reports ◽  
Colon Adenocarcinoma ◽  
The United States ◽  
Punch Biopsy ◽  
Left Breast ◽  
Cutaneous Metastasis ◽  
Cutaneous Lesions ◽  
Cutaneous Metastases ◽  
Colonic Primary

Colorectal cancer (CRC) is the third most diagnosed cancer in the United States, and many patients unfortunately have metastases at the time of their diagnosis. Cutaneous metastases of CRC have been reported in few journals and primarily as case reports due to their rarity. Here, we present the case of an 83-year-old woman with recently resected colon cancer, T4aN1bMx stage IIIB. She presented to our clinic for evaluation of a right midback mass, and a punch biopsy revealed dermal involvement by invasive, poorly differentiated carcinoma with epidermoid features. The mass was excised, and we ordered a PET scan in search of the primary tumor, which at that time was suspected to be of skin cancer origin. Surprisingly, this revealed a second malignancy triple-negative invasive ductal carcinoma of the left breast. The back mass stained positive for CK20, which was compatible with a metastasis from a colonic primary. After initially declining adjuvant therapy, the patient completed one cycle of capecitabine and oxaliplatin, which she tolerated poorly. She continued to further decline, developed widespread cutaneous metastases, and went home on hospice. Cutaneous lesions are an exceedingly rare site of metastasis for colon adenocarcinoma, and their clinical presentation can vary widely. It is important for providers to investigate any new skin lesion in a patient with a recent or remote history of malignancy, even if there were no sites of distant metastasis at initial diagnosis.

scholarly journals A rare case report of incidental solitary uterine metastasis in primary invasive lobular carcinoma of breast

2016 ◽  
Author(s):  
Vivek Gupta ◽  
Amita Mishra ◽  
Namit Kalra ◽  
Bhawna Narula
Keyword(s):  
Rare Case ◽  
Ductal Carcinoma ◽  
Residual Disease ◽  
Histopathological Examination ◽  
Lobular Carcinoma ◽  
Radical Mastectomy ◽  
Left Breast ◽  
Tram Flap ◽  
Metastatic Pattern ◽  
Her Family

Introduction: Infiltrating Lobular carcinoma (ILC) of the breast is second most common cancer of breast next only to Infiltrating ductal carcinoma (IDC). It has a different metastatic pattern as compared to the IDC. Breast cancer is the most frequent primary site which spreads to gynaecologic organs. Case Presentation: A 40 yrs old Iraqi lady presented as a diagnosed case of lobular carcinoma of left breast. She had already undergone a lumpectomy at Iraq a month back and now had come for completion of treatment. On metastatic workup with PETCT scan, we found a multicentric residual disease in the left breast along with some ipsilateral axillary LN with significant uptake. The concurrent CECT done showed a uterine leiomyomam also. As she was strongly hormone receptor positive, had completed her family and was having mennorhagia probably attributable to uterine fibroids. She was offered hysterectomy with B/L salpingo-oophorectomy. She was keen for breast preservation but in view of her multicentricity of disease on the left breast she was counselled for mastectomy with upfront whole breast reconstruction with TRAM flap. She underwent left modified radical mastectomy with hysterectomy with BSO and TRAM flap reconstruction. The histopathological examination revealed a multicentric, multifocal ILC, grade II with heavy nodal involvement including extracapsular extension. The leiomyoma of uterus also showed tumor deposits from lobular carcinoma breast. Conclusion: We report a very rare case of metastatic pattern of carcinoma of breast. On literature review we found that it is common for the lobular carcinomas of breast to metastasise to gynaecologic organs. Uterine corpus is a very rare site of metastasis for extragenital cancers including breast. All the patients of primary lobular carcinoma of breast should be screened for gynaecologic secondaries in the preoperative workup with high degree of suspicion.

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