Riedel’s Thyroiditis: Report of Two Cases and Literature Review

Riedel’s thyroiditis is a rare entity consisting of a fibrotic process of the thyroid which can generate gland destruction, infiltration of cervical structures and even airway obstruction. It has been associated with systemic fibrotic disorders, autoimmune diseases, and more recently with spectrum of diseases related to excess of Immunoglobulin G type 4 (IgG4). Two cases of Riedel’s thyroiditis by IgG4, confirmed by immunohistochemistry and was managed surgically with favorable results during the follow-up time, are presented. These case descriptions highlight the diagnostic challenge of this disease, describe the response with surgical management, and make a brief update on the subject.

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Reidel’s Thyroiditis, a Diagnostic and Management Challenge: A Case Report and Review of the Literature

Case Reports in Endocrinology ◽

10.1155/2021/5185259 ◽

2021 ◽

Vol 2021 ◽

pp. 1-4

Author(s):

Yassine Er-Rahali ◽

Mohammed Massine El Hammoumi ◽

Jad Issouani ◽

Colna Antonio Nfad ◽

Souad El Moussaoui ◽

...

Keyword(s):

Corticosteroid Therapy ◽

Short Review ◽

Needle Aspiration ◽

Diagnostic Challenge ◽

Riedel’S Thyroiditis ◽

Ultrasound Study ◽

Fibrotic Process ◽

Levothyroxine Replacement ◽

Fibrotic Disorders ◽

Riedel's Thyroiditis

Riedel's thyroiditis is a very rare inflammatory condition. It affects not only the thyroid gland but also the adjacent vital structures. It may also be associated with different forms of systemic fibrotic disorders. The exact etiology is unknown, but currently, the most favorable opinion is that it is a localized form of the systemic fibrotic process. We report the case of a 38-year-old woman, presented with a 10-month history of progressive hypothyroidism, dysphonia, and dysphagia. A Doppler ultrasound study revealed massive thyroid enlargement with multiple Eu TIRADS 3 and 4 nodules. Fine needle aspiration was noncontributive on two occasions. A hard subtotal thyroidectomy was performed. Pathological study confirmed Riedel's thyroiditis with the presence of IgG4 antibodies in immunohistochemistry. The patient was successfully treated with levothyroxine replacement and corticosteroid therapy with rapid resolution of obstructive symptoms. The case descriptions highlight the diagnostic challenge of this disease, describe the response to surgical management and corticosteroid therapy, and give a short review of the subject.

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Riedel’s thyroiditis — Case report and literature review

Irish Journal of Medical Science (1971 -) ◽

10.1007/bf02967224 ◽

1994 ◽

Vol 163 (4) ◽

pp. 176-177 ◽

Cited By ~ 4

Author(s):

O. H. Brady ◽

D. J. Hehir ◽

S. J. Heffernan

Keyword(s):

Case Report ◽

Literature Review ◽

Riedel’S Thyroiditis ◽

Riedel's Thyroiditis

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Riedel’s Thyroiditis in an Elderly Male Patient: A Rare Entity

JOURNAL FOR CLINICAL AND DIAGNOSTIC RESEARCH ◽

10.7860/jcdr/2014/9215.5060 ◽

2014 ◽

Author(s):

CHUMILA THINLEY BHUTIA

Keyword(s):

Male Patient ◽

Rare Entity ◽

Elderly Male ◽

Riedel’S Thyroiditis ◽

Riedel's Thyroiditis

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Retroperitoneal Sclerosing Angiomyolipoma with Long-Term Follow up: A Case Report with Unique Clinicopathologic and Genomic Profile

International Journal of Surgical Pathology ◽

10.1177/10668969211021483 ◽

2021 ◽

pp. 106689692110214

Author(s):

Liwei Jia ◽

Vandana Panwar ◽

Michelle Parmley ◽

Elena Lucas ◽

Ivan Pedrosa ◽

...

Keyword(s):

Adipose Tissue ◽

Rare Entity ◽

Genomic Profile ◽

Tissue Component ◽

Diagnostic Challenge ◽

Molecular Alterations ◽

Long Term Follow Up ◽

Distinct Morphology

Sclerosing angiomyolipoma (sAML) is a rare variant of the perivascular epithelioid tumors exhibiting distinct morphology with extensive stromal hyalinization, which makes it challenging to recognize. It often lacks an adipose tissue component and melanocytic markers may be expressed only focally, further posing a diagnostic challenge. Here, we report a case of sAML of the left pararenal retroperitoneum in a 52-year-old woman with 92 months of clinical follow up and discuss the histologic features, immunoprofile, molecular alterations, and differential diagnoses that can aid in the diagnosis of this unique and rare entity.

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Osteosarcoma “tipo osteoblastoma” de columna cervical. A propósito de un caso. [Osteoblastoma like osteosarcoma of the cervical spine]

Revista de la Asociación Argentina de Ortopedia y Traumatología ◽

10.15417/issn.1852-7434.2019.84.2.798 ◽

2019 ◽

Vol 84 (2) ◽

pp. 149-154

Author(s):

Gastón Camino Willhuber ◽

Gonzalo Kido ◽

Martín Estefan ◽

Maximiliano Mereles ◽

Julio Bassani ◽

...

Keyword(s):

Cervical Spine ◽

Surgical Technique ◽

Growth Pattern ◽

Clinical Case ◽

Bone Biopsy ◽

Rare Entity ◽

Diagnostic Challenge ◽

Double Approach ◽

Aggressive Variant

El osteosarcoma “tipo osteoblastoma”, una variante menos agresiva del osteosarcoma, es una enfermedad poco frecuente y representa un desafío diagnóstico tanto clínico como histopatológico. Se han publicado escasos reportes de casos de este tumor.Presentamos a un paciente de 16 años con un osteosarcoma “tipo osteoblastoma” localizado en la columna cervical. La biopsia ósea bajo tomografía reveló una lesión con un patrón de crecimiento permeativo, con sospecha de osteosarcoma “tipo osteoblastoma”. Se realizó una espondilectomía total en bloque mediante un doble abordaje. Se describen el caso clínico, la secuencia diagnóstica, la técnica quirúrgica y el seguimiento a 10 años. ABSTRACT Osteoblastoma-like osteosarcoma; a less aggressive variant of osteosarcoma;is a rare entity and represents a clinical and histopathological diagnostic challenge. We have found few reports of cases of this tumor in the literature. In this case we describe an osteoblastoma-like osteosarcoma located in the cervical spine in a 16-year-old patient. Tomography guided bone biopsy showed a lesion with a permeative growth pattern with suspicion of an osteoblastoma-like osteosarcoma. A total block spondylikectomy wasperformed through a double approach. We present the clinical case, the diagnostic sequence, the surgical technique and 10-year follow-up.

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Amyand’s hernia in a 5-year-old child: a case report and literature review

Journal of Surgical Case Reports ◽

10.1093/jscr/rjaa302 ◽

2020 ◽

Vol 2020 (9) ◽

Author(s):

Bhawani Khanal ◽

Sunit Agrawal ◽

Roshan Gurung ◽

Suresh Sah ◽

Rakesh Kumar Gupta

Keyword(s):

Case Report ◽

Inguinal Hernia ◽

Literature Review ◽

Amyand’S Hernia ◽

Rare Entity ◽

Normal Appendix ◽

Diagnostic Challenge

Abstract Amyand’s hernia in a child is a very rare entity. It poses a diagnostic challenge to the surgeon due to its variety of presentation. We are presenting a case of a 5-year-old child who presented to our institute with right-sided irreducible inguinal hernia. On exploration, the content of the hernia was caecum with normal appendix for which herniotomy with appendectomy was done.

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Dual Chronic Ossified Epidural Hematomas Presented with Seizures 23 Years after Head Injury in an Adult Male: Case Report and Literature Review

Indian Journal of Neurotrauma ◽

10.1055/s-0037-1616032 ◽

2018 ◽

Vol 15 (01) ◽

pp. 041-042

Author(s):

Vivek Agrawal ◽

Pramod Giri

Keyword(s):

Case Report ◽

Head Injury ◽

Literature Review ◽

Rare Case ◽

Age Group ◽

Pediatric Age ◽

Rare Entity ◽

Presenting Symptoms ◽

Pediatric Age Group

AbstractThe authors report a rare case of dual chronic ossified epidural hematomas (EDHs) in a 35-year-old man with complaint of seizures after 23 years of head injury. Ossified EDH is a rare entity, and it commonly presents in pediatric age group. Presenting symptoms include headache and very rarely seizures. Asymptomatic cases may produce symptoms after decades; hence, regular follow-up is required. Treatment includes craniotomy or conservative management.

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Papillary glioneural tumor presenting with multiple ischemic strokes: an aggressive presentation of a “benign” entity

International Surgery Journal ◽

10.18203/2349-2902.isj20212286 ◽

2021 ◽

Vol 8 (6) ◽

pp. 1892

Author(s):

Alejandro Vargas-Moreno ◽

Viviana Cruz-Ramírez ◽

Eugenio Meek-Benigni ◽

Oscar Feo-Lee

Keyword(s):

Literature Review ◽

Clinical Course ◽

Current Knowledge ◽

Histopathological Analysis ◽

Rare Entity ◽

First Case ◽

The Central Nervous System ◽

Treatment Alternatives ◽

Benign Course

Papillary glioneural tumors are infrequent neoplasms of the central nervous system, classically presenting with an indolent clinical course, rarely being related to an aggressive presentation, and not being associated with ischemic or another type of paraneoplastic phenomena. We describe the first case of this type of presentation with a literature review of the current knowledge of this entity. A 16-year-old female presented with a hemorrhagic intra-axial lesion, confirmed to be a papillary glioneural tumor in the histopathological analysis, being associated with multiple ischemic cerebral and posterior fossa strokes without another discernable cause than the presence of a paraneoplastic syndrome, not previously reported with this type of neoplasms. A literature review is presented detailing the current knowledge about this entity and emphasizing the need for greater knowledge about its natural history, immunobiology and treatment alternatives, opening a new window for the study of this pathology and establishing the need for a strict follow-up of patients who have this kind of tumors in order to learn more about their evolution. The papillary glioneural tumor, a rare entity having generally with a benign course, can have different presentations. Greater knowledge is needed to understand this behavior in order to optimize patient’s outcomes.

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Mucoepidermoid Carcinoma of the Breast With MAML2 Rearrangement: A Case Report and Literature Review

International Journal of Surgical Pathology ◽

10.1177/1066896920916779 ◽

2020 ◽

Vol 28 (7) ◽

pp. 787-792 ◽

Cited By ~ 2

Author(s):

Mingfei Yan ◽

Hannah Gilmore ◽

Aparna Harbhajanka

Keyword(s):

Literature Review ◽

Mucoepidermoid Carcinoma ◽

Low Grade ◽

Rare Entity ◽

Carcinoma Of The Breast ◽

Molecular Abnormalities ◽

Molecular Abnormality ◽

Hybridization Test

Mucoepidermoid carcinoma is one of the most common malignancies in salivary glands. In comparison, breast mucoepidermoid carcinoma is a very rare entity, with limited reports and understanding of its clinical behaviors to date. In this article, we report a case of low-grade breast mucoepidermoid carcinoma of a 60-year-old female patient. Histologic and immunohistochemical patterns were demonstrated. Fluorescence in situ hybridization test was also conducted to identify MAML2 rearrangement in this case, indicating a similar molecular abnormality as mucoepidermoid carcinoma in the salivary gland. Five-year follow-up of the patient showed no local recurrence or distant metastasis of the carcinoma, indicating the indolent behavior of low-grade breast mucoepidermoid carcinoma. Besides, a 40-year literature review from 1979 to 2019 was also performed to better characterize the prognosis and molecular abnormalities of the lesion.

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