Behavior of PMMA Denture Base Materials Containing Titanium Dioxide Nanoparticles: A Literature Review

Titanium dioxide nanoparticles (TiO2NP) have gained interest in the dental field because of their multiple uses in addition to their antimicrobial effect. One of the applications in dentistry involves the incorporation into poly methyl methacrylate (PMMA) resin. However, there is a lack of evidence on their effects on the behavior of the resulting nanocomposite. Therefore, the present review aims to screen literatures for data related to PMMA/TiO2nanocomposite to figure out the properties of TiO2nanoparticles, methods of addition, interaction with PMMA resin matrix, and finally the addition effects on the properties of introduced nanocomposite and evidence on its clinical performance. Regardless of the latest research progress of PMMA/TiO2nanocomposite, the questionable properties of final nanocomposite and the lack of long-term clinical evidence addressing their performance restrict their wide clinical use. A conclusive connection between nanoparticle size or addition method and nanocomposite properties could not be established.

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Studying the Mechanical Properties of Denture Base Materials Fabricated from Polymer Composite Materials

Al-Khwarizmi Engineering Journal ◽

10.22153/https://doi.org/10.22153/kej.2018.01.006 ◽

2018 ◽

Vol 14 (3) ◽

pp. 100-111 ◽

Cited By ~ 3

Author(s):

Jawad Kadhim Oleiwi ◽

Qahtan Adnan Hamad

Keyword(s):

Mechanical Properties ◽

Composite Materials ◽

Polymer Composite ◽

Volume Fraction ◽

Mechanical Tests ◽

Polymer Composite Materials ◽

Resin Matrix ◽

Denture Base ◽

Base Materials ◽

Pmma Resin

In this research, the effect of adding two different types of reinforcing particles was investigated, which included: nano-zirconia (nano-ZrO2) particles and micro-lignin particles that were added with different volume fractions of 0.5%, 1%, 1.5% and 2% on the mechanical properties of polymer composite materials. They were prepared in this research, as a complete prosthesis and partial denture base materials was prepared, by using cold cure poly methyl methacrylate (PMMA) resin matrix. The composite specimens in this research consist of two groups according to the types of reinforced particles, were prepared by using casting methods, type (Hand Lay-Up) method. The first group consists of PMMA resin reinforced by (nano-ZrO2) particles, while the second group consists of PMMA resin reinforced by (micro-lignin) particles. The mechanical tests performed in this research includedtensile test, compression test, impact test and hardness test. The results of this study showed that the values of tensile modulus of elasticity, compressive strength and hardness properties increased with increasing the volume fraction of these particles in PMMA composite materials. While, the values of tensile strength, elongation and impact strength properties decreased. Also, the addition of (nano-ZrO2) particles showed greater effect than that of (micro-lignin) particles in some properties of PMMA composite materials for prosthesis denture base materials specimens, while they have lower effect for the other properties.

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Biofilm Formation of Respiratory Pathogens on Vanillin-Incorporated Denture Base Resin

Key Engineering Materials ◽

10.4028/www.scientific.net/kem.801.3 ◽

2019 ◽

Vol 801 ◽

pp. 3-8 ◽

Cited By ~ 3

Author(s):

Sroisiri Thaweboon ◽

Boonyanit Thaweboon ◽

Futoshi Nakazawa

Keyword(s):

Respiratory Infection ◽

Biofilm Formation ◽

Antimicrobial Property ◽

Respiratory Pathogens ◽

Denture Base ◽

Commercial Resin ◽

Base Materials ◽

Base Resin ◽

Pmma Resin ◽

Denture Base Resin

The adherence of microorganisms to denture base materials and the consequent formation of biofilms on these surfaces are contributing factors to biofilm-related oral and systemic diseases. Aspiration pneumonia is a potentially life-threatening respiratory infection associated with the entry of foreign materials into the bronchi. Vanillin-incorporated polymethyl methacrylate (PMMA) resin has been developed for the use in dentistry and demonstrated to have antimicrobial activity. Objective: To evaluate antimicrobial property of vanillin-incorporated PMMA denture base resin on biofilm formation of respiratory pathogens. Materials and methods: The heat polymerized PMMA denture base resin samples (Siam Cement Group, Thailand) were prepared according to the percentage of vanillin incorporation (0%, 0.1% and 0.5% vanillin). Another group of commercial resin samples without vanillin (Triplex®, Ivoclar Vivadent, USA) was prepared in the same manner. All samples were coated with sterile unstimulated saliva collected from three healthy adult volunteers at 37 °C for 60 min. The respiratory pathogenic bacteria used in this study were Staphylococcus aureus ATCC 5638, Streptococcus pneumoniae ATCC 49619, and Pseudomonas aeruginosa ATCC 27853. They were prepared to a concentration of approximately 107 colony forming unit (CFU)/mL. The bacterial biofilm formation was done in 96-well plate and incubated at 37°C for 24-48 h. The amount of biofilm was quantified by Cell Counting Kit WST-8 (Dojindo Molecular Technologies, USA) at 420 nm. All tests were performed in triplicate on three separate occasions. One-way ANOVA and Turkey’s test were used for the statistical analysis. Results: The vanillin-incorporated resin groups (0.1% and 0.5% vanillin) had a significant reduction of S. aureus and P. aeruginosa biofilm mass compared with resins without vanillin (0% vanillin and commercial resin groups). No significant difference was observed in the S. pneumonia biofilm formation. Up to 80% and 33% reductions of biofilm mass were demonstrated on P. aeruginosa and S. aureus, respectively. Conclusion: The incorporation of vanillin to denture base PMMA resin could significantly inhibit biofilm formation of respiratory pathogens. Using this PMMA resin, denture base materials with antimicrobial property can be applied to reduce a risk of respiratory infection in denture wearing patients.

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Oxidative damage of lung and its protective mechanism in mice caused by long-term exposure to titanium dioxide nanoparticles

Journal of Biomedical Materials Research Part A ◽

10.1002/jbm.a.34190 ◽

2012 ◽

Vol 100A (10) ◽

pp. 2554-2562 ◽

Cited By ~ 44

Author(s):

Qingqing Sun ◽

Danlin Tan ◽

Qiuping Zhou ◽

Xiaorun Liu ◽

Zhe Cheng ◽

...

Keyword(s):

Titanium Dioxide ◽

Oxidative Damage ◽

Titanium Dioxide Nanoparticles ◽

Protective Mechanism

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Gene Expression in Liver Injury Caused by Long-term Exposure to Titanium Dioxide Nanoparticles in Mice

Toxicological Sciences ◽

10.1093/toxsci/kfs153 ◽

2012 ◽

Vol 128 (1) ◽

pp. 171-185 ◽

Cited By ~ 59

Author(s):

Yaling Cui ◽

Huiting Liu ◽

Yuguan Ze ◽

Zhang Zengli ◽

Yuanyuan Hu ◽

...

Keyword(s):

Gene Expression ◽

Titanium Dioxide ◽

Liver Injury ◽

Titanium Dioxide Nanoparticles

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Evaluation of the Transverse Strength of the Heat Cure PMMA Resin Reinforced with Various Concentrations of Two Different Nanoparticles: An In vitro Study

Journal of Advances in Medicine and Medical Research ◽

10.9734/jammr/2019/v29i830116 ◽

2019 ◽

pp. 1-8

Author(s):

Kusha Thakur ◽

Archana Nagpal ◽

Rajeev Gupta ◽

Ramit Verma ◽

Rohit Saini ◽

...

Keyword(s):

Titanium Dioxide ◽

Titanium Dioxide Nanoparticles ◽

Testing Machine ◽

Bending Test ◽

Control Group ◽

Transverse Strength ◽

Heat Cure ◽

Group 3 ◽

Post Hoc ◽

Pmma Resin

Purpose: The purpose of the study was to evaluate the effect of titanium dioxide and zirconia nanoparticles on transverse strength of heat cure PMMA resin routinely used for complete denture fabrication. Methods: One hundred samples of PMMA resin were made and divided into five groups (20 samples for each group). The test specimens were divided into five groups depending on the concentration of reinforcing nanoparticles as Group 1,2,3,4 and 5; Group 1: PMMA unreinforced (control group), Group 2: PMMA reinforced with 2.5% nanozirconia, Group 3: PMMA reinforced with 5% nanozirconia, Group 4: PMMA reinforced with 2.5% titanium dioxide nanoparticles, and Group 5: PMMA reinforced with 5% titanium dioxide nanoparticles. Universal testing machine was used to conduct a three-point bending test and evaluate the transverse strength of samples. Comparison of mean transverse strength for various groups was carried out by employing one‑way analysis of variance and Bonferroni post hoc tests. Results: The highest and lowest mean transverse strength were observed in Group 3 and 1, respectively. Bonferroni post hoc test showed increase in transverse strength after reinforcement to be statistically significant between all the groups (P = .05) except between the samples of group G1 and G5 and G2 and G3. Conclusion: Addition of nanoparticles in all concentrations significantly increased transverse strength of heat cure PMMA resin as compared to control group. The best result was obtained after adding 5% of nanozirconia particles to the conventional heat polymerized acrylic resin.

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