scholarly journals Comparison of Valgus Correction Angle between Patients with Developmental Dysplasia Hip and Normal Volunteers Measured by Three-Dimensional Reconstruction and X-Ray

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Aobo Zhang ◽  
Qing Han ◽  
Bingpeng Chen ◽  
Chenyu Wang ◽  
Xue Zhao ◽  
...  

Background and purpose. A new method of three-dimensional (3D) reconstruction technology was used to take place of X-ray in measuring valgus correction angle (VCA) of both DDH patients and normal volunteers to improve precision. Two different ways to define VCA according to the various conditions of patients were compared and analyzed. Methods. Bilateral VCA of 50 DDH patients and 56 normal volunteers were measured by Mimics software in the 3D method and X-ray in 2D. Two VCA (the upper VCA and the lower VCA) were measured in both two methods. Every VCA was measured by observer A and observer B for twice separately. The statistical analyses of the differences were calculated among the measurements of the VCA. Results. The mean value of the upper VCA measured in 3D was 4.95°±0.76° in DDH group and 5.56°±0.62° in the normal group with significant difference (t=−6.457, p<0.01). The VCA of DDH group and normal group measured by 3D was larger than 2D, both the upper VCA and the lower VCA. The differences indicated statistically significant. The mean value of lower VCA was 0.60° smaller than the mean value of upper VCA in normal volunteers. The mean value of the lower VCA was 0.58° larger than the mean value of the upper VCA in DDH patients. Conclusions. Compared to X-ray, 3D reconstruction technology is more accurate without conventional limitations. The lower VCA of DDH patients should be regarded as the femoral intramedullary guide angle in TKA, especially for patients with femoral deformities.

Author(s):  
Hayder A. Hashim ◽  
Najat Al-Sayed ◽  
Ayah AL-Qaisi

Introduction: Cephalometric analysis aims to determine skeletal and dental relationships. The ANB angle, initially suggested by Rediel and applied by Steiner. is the most used angle in establishing the anteroposterior relationship of the mandible to the maxilla. However, limitations to the accuracy of the ANB angle for this purpose have been reported. To avoid these potential sources of inaccuracy a diagnostic tool was introduced by Jenkins and later modified by Jacobson and became known as the “Wits appraisal”. Aims: The aim of this study was to establish the Wits appraisal value in a sample of Qatari males, a group which had not previously been studied in this context, and to compare the findings with those from racially and ethnically differing groups as reported in the literature. Materials and Methods: The sample consisted of 28 lateral cephalometric radiographs of Qatari males with an age range of 15 to 32 years, presenting with a well-balanced facial appearance and an acceptable profile. Results: The mean value of the Wits appraisal for Qatari males in the present study was 0.50 ± 2.96. This differed at a statistically significant level from the mean value in the Jacobson study with no gender significant difference noted. On the other hand, significant differences were found when compared with previous reports on different races. Conclusion: The Wits appraisal value for the Qatari male population studied was 0.5±2.96, a result which is significantly higher than that reported in Jacobson’s study. This study revealed that the Wits appraisal is not ethnicity or gender-specific, and therefore cannot be used to differentiate between different ethnic groups. However, it can find application as an alternative to the ANB angle in the treatment of borderline cases. The application of cone beam computed tomography (CBCT) will enhance the diagnosis and treatment of cases by yielding three-dimensional views.


1995 ◽  
Vol 41 (11) ◽  
pp. 1649-1653 ◽  
Author(s):  
E N Hristova ◽  
S Cecco ◽  
J E Niemela ◽  
N N Rehak ◽  
R J Elin

Abstract We compared two ion-selective analyzers (AVL 988-4 and NOVA CRT) for determining ionized calcium (iCa2+), ionized magnesium (iMg2+), sodium (Na+), and pH in serum specimens from healthy and diseased individuals. For assays of three levels of protein-based control materials, total imprecision (CV) was &lt; 3% for all analytes except iMg2+ (&lt; or = 6.5% on NOVA, and &lt; or = 4.9% on AVL). We found a significant difference between the analyzers (P &lt; 0.001) for the mean iMg2+ concentration in patients but no significant correlation (r = 0.253) between the analyzers for iMg2+ in specimens from healthy volunteers, even though the mean iMg2+ concentration did not differ significantly between these groups. The reference interval (central 95 percentiles) for iMg2+ with AVL (0.44-0.60 mmol/L) was contained within that of NOVA (0.39-0.64 mmol/L). The AVL gave higher values for iCa2+ (P &lt; 0.001) and lower values for pH (P &lt; 0.001) in specimens from normal volunteers and patients. The mean value for Na+ in patients' samples was significantly higher by the NOVA (P &lt; 0.01) than by the AVL analyzer. Thus, we found significant differences between these two analyzers for all four analytes.


2020 ◽  
Vol 5 (4) ◽  
pp. 2473011420S0025
Author(s):  
Zhao Hong-Mou

Category: Hindfoot Introduction/Purpose: Based on a prospective study, a new method of photographing and measuring of hindfoot alignment based on X-ray was proposed, and its reliability is verified, as well as its application in flatfeet. Methods: This study included 28 patients (40 feet) with flatfeet and 20 volunteers (40 feet) from January to December in 2018. The shooting frame, designed by our team, has been used to take the hindfoot alignment view at 10°, 15°, 20°, 25°, 30° respectively. Our modified tibio-hindfoot angles (THA) at standard Saltzman position (shooting at 20°) were evaluated, and the consistency were compared with the van Dijk method and the modified van Dijk method, and compared with weight-bearing CT. The visibility of tibiotalar space were evaluated in all shooting angles. The consistency of the modified THA method at different projection angles were evaluated. The angle of hindfoot valgus of flatfoot patients was measured with use of the modified THA method, and compared in different shooting angles. Results: The mean THA in standard Saltzman view in normal people were significantly differences between the three evaluation methods (P < 0.001). The results of modified THA method were significantly larger than those of Van Dijk method (P < 0.001) and modified Van Dijk method (P < 0.001). There was no significant difference between the results of modified THA method and the weight-bearing CT (P=0.605), and the intra- and inter-group consistency was the best in modified THA group. The tibiotalar space in the normal group were visible in all cases at 10°, 15°, 20°; and visible in some cases at 25°; and invisible in all cases at 30°. In the flatfoot group, the tibiotalar space were visible in all cases at 10°; and in some cases at 15° and 20°; and invisible in all cases at 25° and 30°. In the normal group, the modified THA was 4.84±1.81° at 10°, 4.96±1.77° at 15°, 4.94±2.04° at 20°. No significant difference was found between the three groups (P=0.616). In the flat foot group, the modified THA of 18 feet, which was visible at 10°, 15° and 20°, was 13.58±3.57° at 10°, 13.62±3.83° at 15° and 13.38±4.06° at 20°. There was no significant difference between the three groups (P=0.425). Conclusion: The modified THA evaluation method is simple to use and has high intra- and inter-group consistency. It can be used to evaluate hindfoot alignment. For patients with flatfeet, the 10° position view and modified THA measurement can be used to evaluate the hindfoot valgus conditions.


2016 ◽  
Vol 15 (3) ◽  
pp. 254-262 ◽  
Author(s):  
Mourougan Sinnatamby ◽  
Vivekanandan Nagarajan ◽  
K S. Reddy ◽  
Gunaseelan Karunanidhi ◽  
Vivekanandam Singhavajala

AbstractAimTo compare the image-based three-dimensional treatment planning using AcurosTM BV and AAPM TG-43 algorithm for intracavitary brachytherapy of carcinoma cervix.Materials and methodsTwenty-seven patients with cancer cervix, stage IIB or IIIB with vaginal involvement limited to the upper third of the vagina was included into the study. Intracavitary treatments with the patient in this study done with computed tomography and magnetic resonance imaging compatible ring applicator. Groupe European de Curietherapie and European Society for Therapeutic Radiology and Oncology recommended doses to target volumes and organs at risk compared using dose volume histogram.ResultsThe mean value of Point ‘A’ dose was compared between AcurosTM BV and TG-43, which indicates 0·13% difference. The differences in the mean dose to gross tumour volume for various volumes are V100% 0·28%, V150% 1·22% and V200% 1·03%; all volumes showed small difference but statistical significant (p<0·05). The mean dose of high-risk clinical target volume (HRCTV) D90 using AcurosTM BV was 8·47 Gy, which was 1·63% less compared with TG-43. The mean point A dose using AcurosTM BV is 1·04 times the dose to D90 of mean HRCTV. The same difference was observed in comparison with TG43. D2cc and D0·1cc of the bladder, rectum and sigmoid showed a statistically significant difference (p<0·05) in comparison with TG-43.ConclusionThe differences in dosimetric parameters between the AcurosTM BV and TG-43 proved to be statistically significant. The difference is very small, and they are clinically insignificant.


Author(s):  
Noriyuki Kuwano ◽  
Masaru Itakura ◽  
Kensuke Oki

Pd-Ce alloys exhibit various anomalies in physical properties due to mixed valences of Ce, and the anomalies are thought to be strongly related with the crystal structures. Since Pd and Ce are both heavy elements, relative magnitudes of (fcc-fpd) are so small compared with <f> that superlattice reflections, even if any, sometimes cannot be detected in conventional x-ray powder patterns, where fee and fpd are atomic scattering factors of Ce and Pd, and <f> the mean value in the crystal. However, superlattices in Pd-Ce alloys can be analyzed by electron microscopy, thanks to the high detectability of electron diffraction. In this work, we investigated modulated superstructures in alloys with 12.5 and 15.0 at.%Ce.Ingots of Pd-Ce alloys were prepared in an arc furnace under atmosphere of ultra high purity argon. The disc specimens cut out from the ingots were heat-treated in vacuum and electrothinned to electron transparency by a jet method.


1996 ◽  
Vol 75 (05) ◽  
pp. 772-777 ◽  
Author(s):  
Sybille Albrecht ◽  
Matthias Kotzsch ◽  
Gabriele Siegert ◽  
Thomas Luther ◽  
Heinz Großmann ◽  
...  

SummaryThe plasma tissue factor (TF) concentration was correlated to factor VII concentration (FVIIag) and factor VII activity (FVIIc) in 498 healthy volunteers ranging in age from 17 to 64 years. Immunoassays using monoclonal antibodies (mAbs) were developed for the determination of TF and FVIIag in plasma. The mAbs and the test systems were characterized. The mean value of the TF concentration was 172 ± 135 pg/ml. TF showed no age- and gender-related differences. For the total population, FVIIc, determined by a clotting test, was 110 ± 15% and the factor VIlag was 0.77 ± 0.19 μg/ml. FVII activity was significantly increased with age, whereas the concentration demonstrated no correlation to age in this population. FVII concentration is highly correlated with the activity as measured by clotting assay using rabbit thromboplastin. The ratio between FVIIc and FVIIag was not age-dependent, but demonstrated a significant difference between men and women. Between TF and FVII we could not detect a correlation.


1966 ◽  
Vol 16 (01/02) ◽  
pp. 038-050 ◽  
Author(s):  
Ulla Hedner ◽  
Inga Marie Nilsson ◽  
B Robertson

SummaryThe plasminogen content was determined by a casein method in plasma and serum from 20 normal volunteers. The mean plasminogen content was found to be 10.1 ACU (the arbitrary caseinolytic unit defined in such a way that using a 3% casein solution and a digestion time of 20 min. at 37°C, 10 ACU gave an extinction of 0.300). No difference between serum and plasma regarding the plasminogen content was found.Plasminogen was determined in drained and drained plus washed clots prepared from 2 ml plasma. The highest values found in the drained clots were 0.9 ACU/clot and 0.2 ACU/clot in the drained plus washed clots.Plasminogen was also determined in drained and drained plus washed clots prepared from plasma with added purified plasminogen. The plasminogen was recovered in the washing fluid. According to these tests, then, purified added plasminogen is washed out of the clots.The plasminogen content of 20 thrombi obtained post mortem was also determined. The mean value was found to be 0.7 ACU/cm thrombus. Judging from our results, the “intrinsic clot lysis theory” is not the main mechanism of clot dissolution.


Author(s):  
Yuko Komuro ◽  
Yuji Ohta

Conventionally, the strength of toe plantar flexion (STPF) is measured in a seated position, in which not only the target toe joints but also the knee and particularly ankle joints, are usually restrained. We have developed an approach for the measurement of STPF which does not involve restraint and considers the interactions of adjacent joints of the lower extremities. This study aimed to evaluate this new approach and comparing with the seated approach. A thin, light-weight, rigid plate was attached to the sole of the foot in order to immobilize the toe area. Participants were 13 healthy young women (mean age: 24 ± 4 years). For measurement of STPF with the new approach, participants were instructed to stand, raise the device-wearing leg slightly, plantar flex the ankle, and push the sensor sheet with the toes to exert STPF. The sensor sheet of the F-scan II system was inserted between the foot sole and the plate. For measurement with the seated approach, participants were instructed to sit and push the sensor with the toes. They were required to maintain the hip, knee, and ankle joints at 90°. The mean values of maximum STPF of the 13 participants obtained with each approach were compared. There was no significant difference in mean value of maximum STPF when the two approaches were compared (new: 59 ± 23 N, seated: 47 ± 33 N). The coefficient of variation of maximum STPF was smaller for data obtained with the new approach (new: 39%, seated: 70%). Our simple approach enables measurement of STPF without the need for the restraints that are required for the conventional seated approach. These results suggest that the new approach is a valid method for measurement of STPF.


2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tilahun Fufa Debela ◽  
Zerihun Asefa Hordofa ◽  
Aster Berhe Aregawi ◽  
Demisew Amenu Sori

Abstract Background The consequences of obstetric fistula on affected women are more than the medical condition. It has extensive physical, psychological, social, and economic consequences on them. Obstetric fistula affects the entire health and entire life of women. Women suffering from obstetric fistula are often abandoned by her partner, relatives, and the community. This study aimed to determine the quality of life of obstetrics fistula patients before and after surgical repair. Methods Institutional-based prospective, before and after study design was conducted in the Jimma University Medical Center from November 1, 2019–October 30, 2020. A face-to-face interview was conducted with fistula patients who visited Jimma University Medical center, fistula clinic during the study period. All fistula patients were included in the study. Accordingly, 78 women who underwent surgical repair were interviewed. The means and the standard deviation were computed using conventional statistics formulas. The unpaired t-test was used to compare two independent means, and one-way analysis of variance (ANOVA) was used to compare the quality of life before repair and after a successful repair. Linear regression analysis was done for identifying determinants of quality of life. A P value of 0.05 will be considered statistical significance. Result The overall quality of life of women was 58.17 ± 7.2 before the surgical repair and 71.20 ± 10.79 after surgical repair. The result indicates there is a significant difference in the mean value of pre and post-operative (P < 0.001). The overall satisfaction of women with their health status before the surgical repair was 22.5 ± 1.30and it has increased to 53.0 ± .90after surgical repair. The physical health dimension score was 16.51 ± 5.27 before the surgical repair while it has increased to 21.77 ± 5.38 after the surgical repair. The score of the social domain before the surgical repair was 5.19 ± 1.34 and it has increased to 7.13 ± 3.67 after the surgical repair. The score of the environmental health domain was 17.41 ± 2.89 before the surgery while it also increased to 21.65 ± 4.04 after the surgical repair. The results have shown there was a significant difference in the mean values of pre and post-operatives in both social and environmental scores (P < 0.001). The score of the psychological health domain before the surgery was 19.06 ± 1.46 and it was increased to 19.84 ± 3.21 after the surgical repair. The result showed there is a significant difference in mean value pre and post-operative (P = 0.048), though it is a slight improvement compared to other domains. Conclusion The overall quality of life of the patient with fistula was improved after successful surgical repair. Although all domains of quality of life had shown significant improvement after successful surgical repair, the psychological domain showed slight improvement.


Biology ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 358
Author(s):  
Javier Aragoneses ◽  
Ana Suárez ◽  
Nansi López-Valverde ◽  
Francisco Martínez-Martínez ◽  
Juan Manuel Aragoneses

The aim of this study was to evaluate the effect of implant surface treatment with carboxyethylphosphonic acid and fibroblast growth factor 2 on the bone–implant interface during the osseointegration period in vivo using an animal model. The present research was carried out in six minipigs, in whose left tibia implants were inserted as follows: eight implants with a standard surface treatment, for the control group, and eight implants with a surface treatment of carboxyethylphosphonic acid and immobilization of FGF-2, for the test group. At 4 weeks after the insertion of the implants, the animals were sacrificed for the histomorphometric analysis of the samples. The means of the results for the implant–bone contact variable (BIC) were 46.39 ± 17.49% for the test group and 34.00 ± 9.92% for the control group; the difference was not statistically significant. For the corrected implant–bone contact variable (BICc), the mean value of the test group was 60.48 ± 18.11%, and that for the control group, 43.08 ± 10.77%; the difference was statistically significant (p-value = 0.035). The new bone formation (BV/TV) showed average results of 27.28 ± 3.88% for the test group and 26.63 ± 7.90% for the control group, meaning that the differences were not statistically significant (p-value = 0.839). Regarding the bone density at the interthread level (BAI/TA), the mean value of the test group was 32.27 ± 6.70%, and that of the control group was 32.91 ± 7.76%, with a p-value of 0.863, while for the peri-implant density (BAP/TA), the mean value of the test group was 44.96 ± 7.55%, and that for the control group was 44.80 ± 8.68%, without a significant difference between the groups. The current research only found a significant difference for the bone–implant contact at the cortical level; therefore, it could be considered that FGF-2 acts on the mineralization of bone tissue. The application of carboxyethylphosphonic acid on the surface of implants can be considered a promising alternative as a biomimetic coating for the immobilization of FGF-2. Despite no differences in the new bone formation around the implants or in the interthread or peri-implant bone density being detected, the biofunctionalization of the implant surface with FGF-2 accelerates the mineralization of the bone–implant interface at the cortical level, thereby reducing the osseointegration period.


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