scholarly journals Apexification with Calcium Hydroxide vs. Revascularization

2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
H. Boufdil ◽  
M. Mtalsi ◽  
S. El Arabi ◽  
B. Bousfiha
Keyword(s):  
Calcium Hydroxide ◽  
Clinical Case ◽  
Therapeutic Option ◽  
Pediatric Dentistry ◽  
Therapeutic Options ◽  
Root Structure ◽  
Immature Teeth ◽  
Therapeutic Procedures ◽  
Real Challenge

Treatment of necrotic immature teeth has always been a real challenge for the clinician due to the open apex and weak root structure, which does not allow a conventional endodontic treatment. Several therapeutic options are possible to treat those teeth. Calcium hydroxide apexification is the oldest and most studied therapeutic option, but it has some disadvantages, including the long term of treatment, the possibility of reinfection, and the weakness of the wall. To solve these problems, several authors recommend the revascularization technique. This therapy allows the continuation of root edification with apical closure and thickening of the walls. The aim of our work is to compare the two therapeutic procedures, apexification with calcium hydroxide and revascularization, through a clinical case treated and followed up for 24 months at the pediatric dentistry department in Casablanca, Morocco.

Intentional Replantation of an Immature Incisor with a Transverse Root Fracture and Endo-Perio Condition: 4 Year Follow-Up

2017 ◽  
Vol 41 (3) ◽  
pp. 187-192
Author(s):  
Atsushi Oishi
Keyword(s):  
Calcium Hydroxide ◽  
Root Canal ◽  
Dental Trauma ◽  
Final Diagnosis ◽  
Radiographic Examination ◽  
Initial Examination ◽  
Root Canal Filling ◽  
Root Fracture ◽  
Immature Teeth

This case report describes the importance of continual examination for dental trauma and the efficacy of intentional replantation with retrograde root canal filling for a transverse root fracture in an immature incisor accompanied by subsequent periodontal-endodontic disease. In the treatment of traumatically fractured roots in immature incisors, continual examination is indispensable for the final diagnosis because roots in immature teeth are less calcified, resulting in less detailed radiological examinations. Thus, common dental trauma complications such as pulp necrosis may appear months after the initial examination. Endodontic treatment for transverse root fracture is mainly determined according to radiographic examination findings; for fractured immature roots, apexification with calcium hydroxide of the coronal fragment is generally applied. However, this method requires removal of considerable amounts of enamel and dentin to allow access to the cavity for preparation, which may increase the risk of future fractures. In contrast, intentional replantation with retrograde root canal filling does not require the removal or long-term application of calcium hydroxide. However, it requires careful extraction of the tooth, maintenance of root wetness during the extraoral procedure, rigid splinting, and oral hygiene control. Management of tooth mobility is also important in the post-replantation course.

scholarly journals Novel Therapeutic Approaches to the Treatment of Chronic Abdominal Visceral Pain

2006 ◽  
Vol 6 ◽  
pp. 472-490 ◽  
Author(s):  
Franca Patrizi ◽  
Steven D. Freedman ◽  
Alvaro Pascual-Leone ◽  
Felipe Fregni
Keyword(s):  
Chronic Pain ◽  
Nervous System ◽  
Visceral Pain ◽  
Pain Treatment ◽  
Therapeutic Option ◽  
Therapeutic Options ◽  
Central Nervous System Stimulation ◽  
Chronic Pain Treatment ◽  
Novel Therapeutic

Chronic abdominal visceral pain (CAVP) has a significant clinical impact and represents one of the most frequent and debilitating disorders in the general population. It also leads to a significant economic burden due to workdays lost, reduced productivity, and long-term use of medications with their associated side effects. Despite the availability of several therapeutic options, the management of patients with CAVP is often inadequate, resulting in frustration for both patients and physicians. This may in part be explained by the lack of understanding of the mechanisms underlying chronic pain; in contrast with acute pain in which the pathophysiology is relatively well known and has several satisfactory therapeutic options. Recently, the development of tools for brain investigation, such as functional magnetic resonance imaging, has provided new insights on the pathophysiology of chronic pain. These new data have shown that plastic changes in the central and peripheral nervous system might play an important role in the maintenance of chronic pain. Therefore, approaches aimed at the modulation of the nervous system, rather than the ones interfering with the inflammatory pathways, may be more effective for chronic pain treatment. We propose that noninvasive central nervous system stimulation, with transcranial magnetic stimulation (TMS), might be a novel therapeutic option for CAVP. This paper will present an overview of the pathophysiology and the available therapies for CAVP, focusing on the recent advances in the treatment of this pathology.

scholarly journals Pulp revascularization: an alternative treatment to the apexification of immature teeth

2014 ◽  
Vol 62 (4) ◽  
pp. 401-410
Author(s):  
Maria Tereza Pedrosa ALBUQUERQUE ◽  
Juliana Yuri NAGATA ◽  
Adriana de Jesus SOARES ◽  
Alexandre Augusto ZAIA
Keyword(s):  
Calcium Hydroxide ◽  
Alternative Treatment ◽  
Treatment Protocols ◽  
Immature Teeth ◽  
Hygroscopic Properties ◽  
Proteolytic Activities ◽  
New Treatment ◽  
Treatment Alternatives ◽  
Pulp Revascularization

Pulp revascularization can be considered as a current alternative treatment to apexification, recommended for immature teeth cases, requiring endodontic treatment. Apexification involves long-term periodic exchanges of a calcium hydroxide paste into the root canal to induce the formation of a calcified barrier. Despite being the most classically therapy employed for these cases, the permanence of calcium hydroxide for long periods of time and also the successive changes may lead to a weakening of the root due to its hygroscopic properties and the proteolytic activities of calcium hydroxide, increasing the risk of fractures and contamination of the pulp space. Thus, a constant search for new treatment alternatives that provide the end of root development have been done to avoid the risk of future root fractures. So, revascularization has emerged as a new treatment option for cases of undeveloped teeth, that provides not only apical closure, as apexification, but also increase the dentin walls thickness. In the literature, there is an assortment of treatment protocols employing pulp revascularization procedure in attempt to attain the best way to achieve success. Assuming the diversity of protocols for revascularization treatment, it is important to go deep in the literature to collect, describe and discuss these protocols guiding new researches in this field and also conducting the clinicians. Therefore, this review aims to assess the literature on the different revascularization protocols.

CLINICAL CASE OF LONG-TERM RESULTS OF KERATO-REFRACTIVE SURGERIES IN A PATIENT WITH A HIGH MYOPIA

2019 ◽  
Vol 21 (4) ◽  
pp. 14-16
Author(s):  
M.A. Frolov ◽  
◽  
P.A. Gonchar ◽  
V.A. Biletskaya ◽  
E.S. Belyaeva ◽  
...  
Keyword(s):  
High Myopia ◽  
Clinical Case ◽  
Long Term Results

scholarly journals Protein recycling and limb muscle recovery after critical illness in slow- and fast-twitch limb muscle

2019 ◽  
Vol 316 (5) ◽  
pp. R584-R593 ◽  
Author(s):  
Sebastien Preau ◽  
Michael Ambler ◽  
Anna Sigurta ◽  
Anna Kleyman ◽  
Alex Dyson ◽  
...  
Keyword(s):  
Critical Illness ◽  
Functional Disability ◽  
Ex Vivo ◽  
Therapeutic Option ◽  
Limb Muscle ◽  
Fungal Cell ◽  
Hindlimb Muscles ◽  
Initial Reduction ◽  
Male Wistar Rats

An impaired capacity of muscle to regenerate after critical illness results in long-term functional disability. We previously described in a long-term rat peritonitis model that gastrocnemius displays near-normal histology whereas soleus demonstrates a necrotizing phenotype. We thus investigated the link between the necrotizing phenotype of critical illness myopathy and proteasome activity in these two limb muscles. We studied male Wistar rats that underwent an intraperitoneal injection of the fungal cell wall constituent zymosan or n-saline as a sham-treated control. Rats ( n = 74) were killed at 2, 7, and 14 days postintervention with gastrocnemius and soleus muscle removed and studied ex vivo. Zymosan-treated animals displayed an initial reduction of body weight but a persistent decrease in mass of both lower hindlimb muscles. Zymosan increased chymotrypsin- and trypsin-like proteasome activities in gastrocnemius at days 2 and 7 but in soleus at day 2 only. Activated caspases-3 and -9, polyubiquitin proteins, and 14-kDa fragments of myofibrillar actin (proteasome substrates) remained persistently increased from day 2 to day 14 in soleus but not in gastrocnemius. These results suggest that a relative proteasome deficiency in soleus is associated with a necrotizing phenotype during long-term critical illness. Rescuing proteasome clearance may offer a potential therapeutic option to prevent long-term functional disability in critically ill patients.

Vagus nerve stimulation for drug-resistant epilepsy

2019 ◽  
Vol 20 (3) ◽  
pp. 189-198 ◽  
Author(s):  
Laura Pérez-Carbonell ◽  
Howard Faulkner ◽  
Sean Higgins ◽  
Michalis Koutroumanidis ◽  
Guy Leschziner
Keyword(s):  
Vagus Nerve ◽  
Seizure Frequency ◽  
Nerve Stimulation ◽  
Vagus Nerve Stimulation ◽  
Therapeutic Option ◽  
Drug Resistant ◽  
Drug Resistant Epilepsy ◽  
Randomised Controlled

Vagus nerve stimulation (VNS) is a neuromodulatory therapeutic option for drug-resistant epilepsy. In randomised controlled trials, VNS implantation has resulted in over 50% reduction in seizure frequency in 26%–40% of patients within 1 year. Long-term uncontrolled studies suggest better responses to VNS over time; however, the assessment of other potential predictive factors has led to contradictory results. Although initially designed for managing focal seizures, its use has been extended to other forms of drug-resistant epilepsy. In this review, we discuss the evidence supporting the use of VNS, its impact on seizure frequency and quality of life, and common adverse effects of this therapy. We also include practical guidance for the approach to and the management of patients with VNS in situ.

‘Psychosis of civilization’: a colonial-situated diagnosis

2020 ◽  
pp. 0957154X2096806
Author(s):  
Marianna Scarfone
Keyword(s):  
Clinical Case ◽  
Inner Life ◽  
Differential Approach ◽  
Psychiatric Institutions ◽  
New Material

In the late 1930s, when colonial psychiatry was well established in the Maghreb, the diagnosis ‘psychosis of civilization’ appeared in some psychiatrists’ writings. Through the clinical case of a Libyan woman treated by the Italian psychiatrist Angelo Bravi in Tripoli, this article explores its emergence and its specificity in a differential approach, and highlights its main characteristics. The term applied to subjects poised between two worlds: incapable of becoming ‘like’ Europeans – a goal to which they seem to aspire – but too far from their ‘ancestral habits’ to revert for a quiet life. The visits of these subjects to colonial psychiatric institutions, provided valuable new material for psychiatrists: to see how colonization impacted inner life and to raise awareness of the long-term socio-political dangers.

Calcium hydroxide induced apexification with apical root development: a clinical case report

2008 ◽  
Vol 41 (8) ◽  
pp. 710-719 ◽  
Author(s):  
J. Soares ◽  
S. Santos ◽  
C. Csar ◽  
P. Silva ◽  
M. S ◽  
...  
Keyword(s):  
Case Report ◽  
Calcium Hydroxide ◽  
Root Development ◽  
Clinical Case
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