scholarly journals Clinical Pilot Study of Rectal Suppository Containing Combined Extract of Cissus quadrangularis Linn. and Acmella paniculata (Wall ex. DC.) R. K. Jansen in Acute Hemorrhoids

2021 ◽  
Vol 2021 ◽  
pp. 1-6
Author(s):  
Kanokporn Niwatananun ◽  
Wirat Niwatananun ◽  
Sirivipa Piyamongkol ◽  
Darunee Hongwiset ◽  
Chidchanok Ruengorn ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Good Evidence ◽  
Oral Dosage ◽  
Anal Pain ◽  
Herbal Products ◽  
Good Safety Profile ◽  
Primary Endpoints ◽  
Rectal Suppository ◽  
Cissus Quadrangularis ◽  
Rectal Suppositories

Background. Cissus quadrangularis Linn. (CQ) is a medicinal plant with good evidence for the treatment of hemorrhoids, listed in the Thai National List of Herbal Products in the oral dosage form. Acmella paniculata (Wall ex. DC.) R. K. Jansen. (AP) is a medicinal plant with a local anesthetic effect. Objective. To investigate the potential of rectal suppositories containing CQ and AP extracts to alleviate symptoms of hemorrhoids compared with the commercialized rectal suppository containing hydrocortisone and cinchocaine. Materials and Methods. Hemorrhoid outpatients (n = 105) with different severity grades (I, II, or III) from eight hospitals in northern Thailand were included in this study. Hemorrhoid severity was graded by proctoscopy associated with either anal pain or bleeding related to hemorrhoids or both. The patients were randomly allocated to two groups: CQ-AP group (n = 52) or the commercialized rectal suppository group (n = 53). One suppository was rectally administered twice daily in the morning and at bedtime for seven days. Evaluations were performed by physicians on days 1, 4, and 8 of the study. The primary endpoints were bleeding and prolapse size, while the secondary endpoint was anal pain. Results. Baseline demographics, lifestyle, constipation, number of prolapses, grade of hemorrhoid severity, and duration of experiencing hemorrhoids were comparable in both groups of patients. The effects of CQ-AP and the commercialized rectal suppository on bleeding, prolapse size, and anal pain were comparable. The patients in both groups were satisfied with both products at comparable levels and stated a preference for further use in the case of hemorrhoids recurrence. In terms of safety, the patients in the commercialized rectal suppository group experienced a higher incidence of adverse events, including anal pain and bleeding. Conclusion. Rectal suppositories containing a combined extract of CQ and AP show potential in alleviating hemorrhoidal symptoms with a good safety profile.

Patterns of Specific Antimigraine Drug use – A Study Based on the Records of 18 Community Pharmacies

Cephalalgia ◽  
2005 ◽  
Vol 25 (3) ◽  
pp. 214-218 ◽  
Author(s):  
JJHM Lohman ◽  
MM van der Kuy-de Ree ◽  
Keyword(s):  
Dosage Forms ◽  
Oral Dosage ◽  
Drug Usage ◽  
Subcutaneous Injections ◽  
Nasal Sprays ◽  
Usage Patterns ◽  
Multiple Drugs ◽  
Oral Dosage Forms ◽  
Rectal Suppositories ◽  
Dispensing Data

The objective of this study was, first, to characterize the usage patterns of specific antimigraine drugs, and second, to compare these in patients with one type of drug with patients with two or more types of drug. Dispensing data on triptans and ergotamine were collected from community pharmacy records over a 1-year period. In a population of approximately 168 000 specific antimigraine medication has been dispensed to 2343 patients (1.4%). Oral dosage forms were prescribed in most prescriptions (77.1%), subcutaneous injections in 9.7%, rectal suppositories in 7.1% and nasal sprays in 6.1%. We identified 292 patients (12.5%) to whom more than one type of drug was dispensed. Multiple drugs patients showed significantly higher drug consumption and deviating patterns of specific antimigraine drug usage, receiving significantly more non-oral dosage forms (32.8% vs. 20.4%, P < 0.001). Our data indicate substantially suboptimal treatment of migraine patients.

scholarly journals An Overview of Methods of Extraction, Isolation and Characterization of Natural Medicinal Plant Products in Improved Traditional Medicine Research

2020 ◽  
pp. 31-57
Author(s):  
Dobgima John Fonmboh ◽  
Ejoh Richard Abah ◽  
Tembe Estella Fokunang ◽  
Bayaga Herve ◽  
Gerald Ngo Teke ◽  
...  
Keyword(s):  
Medicinal Plant ◽  
Traditional Medicine ◽  
Chemical Diversity ◽  
Bioactive Metabolites ◽  
Plant Biodiversity ◽  
Phytochemical Screening ◽  
Herbal Products ◽  
Isolation And Characterization ◽  
Herbal Plants

Herbal plants are very important in traditional community use and enrich our plant biodiversity and conservation. Natural products are vital substances of traditional knowledge systems in complementary and alternative medicine, nutraceutical, food supplements, and pharmaceutical bioactive metabolites of new chemical entities. Bioactive secondary metabolites from herbal plants of different forms are main sources and provide major opportunities for drug active pharmaceuticals due to the diverse flora and fauna biodiversity that produces the necessary available chemical diversity. There has been an increasing popularity in phytochemical research within the high through put (HTS) screening programs in search of lead. Phytochemicals of herbal extracts for traditional uses contain various types of bioactive metabolites of pharmaceutical and pharmacotherapeutic nature, and many phytomedicines for different therapeutic areas have been derived from herbal products. This paper is aimed at giving an insight into the extraction, isolation, and characterization of the rich medicinal plant biodiversity of potential pharmaceutical importance and the major drawbacks and challenges in the extraction, isolation, and characterization of phytochemicals in plant extracts. Phytochemicals in medicinal plants have been studied with more emphasis on the extraction process which is a vital stage in the analysis of bioactive compounds in medicinal plant research. The advantages and disadvantages of the different extraction methods is important to discuss following the regulatory guidelines and different pharmacopoeia. The analysis of bioactive molecules in herbal products involves the applications of various phytochemical screening methods, and the use of chromatographic techniques such as TLC and HPLC, including in some cases the non-chromatographic methods like Fourier Transform Infra-Red (FTIR), immunoassay. This paper has been motivated by the challenges faced by most pharmacy students in data mining of information on phytochemical screening and testing of biological activities in projects related to herbal plants research. This write up is also geared towards providing students with information on the preclinical drug discovery process towards the formulation of an improved traditional medicine/ phytomedicine.

scholarly journals Phytomedicine - A Holistic Approach in Dentistry

2016 ◽  
Vol 4 (1) ◽  
Author(s):  
Rita Zarina ◽  
Jaini. J. L ◽  
Ektah Khosla
Keyword(s):  
Medicinal Plant ◽  
Folk Medicine ◽  
Holistic Approach ◽  
Herbal Products ◽  
Antibiotic Overuse ◽  
Ancient Times ◽  
Anti Inflammatory ◽  
Sedative Agents ◽  
Microbiological Properties

<div><p><em>Herbal products have been used since ancient times in folk medicine, involving both eastern and western medicinal traditions. Many plants with biological and anti-microbiological properties have been studied since there has been a relevant increase in the incidence of antibiotic overuse and misuse. In dentistry Phytomedicines has been used as anti-inflammatory, antibiotic, analgesic and sedative agents. This paper highlights certain medicinal plant which is used in dentistry as alternative and in holistic way.</em></p></div>

scholarly journals Pendampingan Pengolahan dan Pengemasan Tanaman Obat Keluarga di Dusun Kemesu Kulon Progo Daerah Istimewa Yogyakarta

2020 ◽  
Vol 5 (2) ◽  
pp. 146-153
Author(s):  
Barbara Gunawan
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Added Value ◽  
Family Welfare ◽  
Herbal Products ◽  
Business Partners ◽  
The Family ◽  
Branded Product ◽  
And Training ◽  
Special Region

The purpose of this service is to provide training and assistance on the processing and packaging of medicinal plants to develop an economically independent community. Business partners in this program Family Welfare Movement, Kemesu village, Kulon Progo Regency, Special Region of Yogyakarta. The problem faced by a partner is the lack of knowledge about how to process medicinal plants so that they can be of added value and can be sold so that they can increase income for the family. The method used to solve the problem is by Providing counseling about the use of medicinal plants, Providing training in the manufacture of herbal drink bag product, Providing training and assistance on how to pack herbal drink bag product, and providing training and assistance on how to marketing herbal drink bag product. The final results showed an increase in knowledge after being given education and training, namely the manufacture of herbal products to be packaged and branded, product marketing, obtaining PIRT from the Health Office of the Kulon Progo Regency until printed and distributed by the Family Medicinal Plant Guidebook.

scholarly journals A case report on the effect of Cissus quadrangularis on fracture union in 26 years aged man

2019 ◽  
Vol 6 (1) ◽  
pp. 224
Author(s):  
Naveen Kumar L. ◽  
Dharitri Joshi
Keyword(s):  
Case Report ◽  
Medicinal Plant ◽  
Bone Healing ◽  
Post Treatment ◽  
Fracture Union ◽  
Ancient Science ◽  
Bennett’S Fracture ◽  
Cissus Quadrangularis ◽  
Reduction Of Pain

<p class="abstract">Ayurveda the ancient science of medicine describes various herb preparations that achieve the hastening of bone healing<em>. Cissus quadrangularis Linn</em>. is an indigenous medicinal plant which belongs to a family of Vitaceae. A case study was undertaken to evaluate the fracture union and effectiveness in reduction of pain and swelling in a 26 year old male with Bennett’s fracture. A quick union of fracture was observed within 6 weeks of treatment with <em>C. quadrangularis</em>. Post treatment radiographic reports showed united fracture with good amount of callus.</p>

scholarly journals Genetic status of Centella asiatica (L.) Urb. (Indian pennywort): A review

2021 ◽  
pp. 150-160
Author(s):  
Sakthipriya Mathavaraj ◽  
Kalluvettankuzhy Krishnannair Sabu
Keyword(s):  
Genetic Variation ◽  
Medicinal Plants ◽  
Medicinal Plant ◽  
Centella Asiatica ◽  
Genetic Studies ◽  
Herbal Products ◽  
Cosmetic Industry ◽  
Genetic Status ◽  
Herbal Medicinal ◽  
Important Medicinal Plant

In recent years, demand for medicinal plants increased due to the rise in attraction towards herbal products which are safer compared to modern drugs. Centella asiatica (L.) Urb is known as an important medicinal plant in herbal medicinal systems. It also used as an active ingredient for many products in the pharmaceutical and cosmetic industry. So far, review on this plant concerns mainly on medicinal, cosmetology and photochemical works reported. This review presents the genetic studies conducted in this herb along with a mention on conservation. Since documenting and studying genetic variation and its composition has an important connection for the understanding of evolution and improving the conservation of this species.

Cultivation of Some Medicinal Climbers in Perspectives of Herbo-Agroforestry System

2016 ◽  
Vol 39 (1) ◽  
pp. 41-44
Author(s):  
Kaushal Kumar
Keyword(s):  
Medicinal Plants ◽  
Natural Habitat ◽  
Agroforestry System ◽  
Tinospora Cordifolia ◽  
Mucuna Pruriens ◽  
Asparagus Racemosus ◽  
Herbal Products ◽  
Hemidesmus Indicus ◽  
Cissus Quadrangularis ◽  
Over Exploitation

There are considerable demands in market for the production of herbal products particularly for pharmacies of ayurveda based on plant products of medicinal climbers like Abrus precatorius, Asparagus racemosus, Caesalpinia bonduc, Celastrus paniculatus, Cissampelos pariera, Cissus quadrangularis, Gymnema sylvestre, Hemidesmus indicus, Ichnocarpus frutescens, Mucuna pruriens, Paederia scandens, Tinospora cordifolia etc. But, due to over exploitation and collection of above plants, it becomes rare in their natural habitat. The farmers and growers of medicinal plants are often taking less interest for cultivation of above medicinal climbers. In the above context, it is delineated herewith enumeration of some medicinal plants mostly climbers for cultivation under Herbo-Agroforestry System (HAS) besides the cultivation of other crops and maintenances of components under the canopy of trees. It would be a suitable option for conservation of valuable medicinal climbers.

scholarly journals Utilization of Plants for Medicinal Purposes and Concerns with Endangered Plant Species from Ghana

2021 ◽  
Author(s):  
Alfred Ofori Agyemang ◽  
Bernard Kofi Turkson ◽  
Michael Frimpong Baidoo ◽  
Isaac Kingsley Amponsah ◽  
Merlin Lincoln Kwao Mensah ◽  
...  
Keyword(s):  
Medicinal Plants ◽  
Medicinal Plant ◽  
Plant Species ◽  
Healthcare Services ◽  
Medicinal Plant Species ◽  
Herbal Products ◽  
Endangered Medicinal Plant ◽  
Important Relationship ◽  
Pharmaceutical Agents ◽  
Drug Leads

There has always been a strong human dependency on plants for health purposes and such an important relationship should be sustained. Plants remain a repository of drug leads for discovering new pharmaceutical agents for prevention, treatment and improving the quality of health for many people globally. In the effort to improve healthcare services, Ghana put up the Recommended Essential Herbal Medicine List (REHML) consisting of products that are used in the treatment of both Communicable and non-Communicable diseases. To inspire confidence among prescribers and clients of the products it has become necessary to validate the plants and their products. The aim of the study was to identify the medicinal plants' species in the herbal products in Ghana’s REHML commonly used for treatment, the conditions being treated with them and finding published research for the plants therapeutic use. Medicinal plants on the REHML with chances of getting extinct were also assessed. The REHML of Ghana and the Ghana Herbal Pharmacopoeia were reviewed for the required information. Electronic databases; PubMed and Scopus, as well as online search engines, Google Scholar and Google were used to obtain information on the identified medicinal plants and their families. A total of 167 medicinal plant species were found to be used in 180 products as compiled in the Ghana REHML and these belonged to 63 botanical families. Most of the medicinal plants are collected from the wild making sustainability and bio-conservation a challenge. Decoctions, creams and ointments are the commonest dosage forms. The REHML of Ghana caters for 13 disease areas using 180 finished herbal products. These products are made from 167 medicinal plants, 16 of which are in the group of medicinal plants classified as endangered species. There should be a conscious effort to bio-conserve these endangered medicinal plant species so that there can be continuous supply for use in the preparation of herbal products for healthcare purposes. 

Sign in / Sign up

Export Citation Format

Share Document