scholarly journals Intercellular Interactions in Peripheral Venous Blood in Practically Healthy Residents of High Latitudes

2021 ◽  
Vol 2021 ◽  
pp. 1-11
Author(s):  
L. K. Dobrodeeva ◽  
A. V. Samodova ◽  
S. N. Balashova ◽  
K. O. Pashinskaya
Keyword(s):  
Venous Blood ◽  
Statistical Processing ◽  
Climatic Conditions ◽  
Biologically Active ◽  
The Arctic ◽  
Neutrophilic Granulocytes ◽  
Immunological Parameters ◽  
Peripheral Venous Blood ◽  
Aggregation Of Erythrocytes ◽  
Hematological Analysis

The paper presents the results of studying the immunological parameters of 369 people who were practically healthy at the time of the survey, 298 women and 71 men, of which 216 people are living in the European North of the Russian Federation (173 women and 43 men) and 153 are residents of the Arctic (125 women and 28 men). The study was carried out in the morning (08:00–10:00 am). The study included the determination of the aggregation of erythrocytes, platelets, neutrophilic granulocytes, lymphocytes, hemogram study, hematological analysis, enzyme immunoassay, and flow cytometry. Statistical processing of the obtained data was carried out using the Statistica 7.0 software package (StatSoft, USA). It was found that the activity of aggregation of cells of peripheral venous blood in Arctic residents is 1.5–1.7 times higher than that in people living in more favourable climatic conditions. The frequency of registration of aggregation of erythrocytes and platelets is actually 2 times higher than the aggregation of leukocytes. Aggregation of erythrocytes is associated with an increase in the concentrations of transferrin and receptors for this transport protein. The frequency of detection of platelet aggregation is accompanied by an increase in transferrin concentrations; in cases of aggregation of nonnuclear blood cells, the content of NO2 in the blood serum is increased. Aggregation of neutrophilic granulocytes and lymphocytes is associated with an increase in the content of free adhesion molecules. Aggregation of erythrocytes and platelets is in evidence when it is necessary to trigger reactions of changes in the hemodynamics of microcirculation to increase the efficiency of oxygen and trophic supply of tissues. The adhesion of leukocytes to the endothelium determines the secretion of biologically active substances that contribute to a change in microcirculation and an increase in the migration of leukocytes into tissues for the implementation of phagocytic and cytolytic functions.

scholarly journals EXTRACTION OF FLAVONOIDS FROM KOENIGIA WEYRICHII USING DEEP EUTECTIC MIXTURE OF CHOLINE CHLORIDE + GLYCERINE

2021 ◽  
pp. 199-206
Author(s):  
Nikita Sergeyevich Tsvetov ◽  
Anna Viktorovna Korovkina ◽  
Oksana Ivanovna Paukshta
Keyword(s):  
High Efficiency ◽  
Choline Chloride ◽  
Eutectic Mixture ◽  
Total Content ◽  
Climatic Conditions ◽  
Biologically Active Substances ◽  
Biologically Active ◽  
The Arctic ◽  
Promising Source ◽  
Active Substances

Koenigia Weyrichii (F. Schmidt) T.M. Schust. et Reveal, which grows on the Kola Peninsula, contains a significant amount of flavonoids in the aerial parts of the plant, rapidly builds up biomass, and is resistant to various climatic conditions. This makes K. Weyrichii a promising source of biologically active substances (BAS) in the Arctic zone. A relatively new method for extracting biologically active substances from plants is the use of deep eutectic solvents (DES), for example, a mixture of choline chloride with glycerol, which has shown high efficiency in the extraction of flavonoids from other plants. Previously, DES was not used for the extraction of biologically active substances from K. Weyrichii. The aim of this work is to evaluate the efficiency of ultrasonic extraction using traditional solvents (water, ethanol) and DES choline chloride + glycerol and to optimize the extraction conditions. Comparison of the total content of polyphenols, flavonoids, antioxidative, and antiradical activity in various extracts is carried out. It was found that the most favorable conditions for extraction are: water content in DES – 17.5 wt%, temperature – 65 °C, and time – 3 hours. At the same time, under identical extraction conditions (temperature and time), more target substances can be extracted with 60% ethanol than with DES. However, DES can be seen as an alternative to using ethanol. The data obtained can be useful for the further development of innovative technologies of the extraction of biologically active substances from plant material. Also, K. Weyrichii may be considered as a source of biologically active substances in cosmetics and the food industry.

Platelet Hyperaggregability in Ischemic Cerebrovascular Disease and Effects of Aspirin

1982 ◽  
Vol 48 (02) ◽  
pp. 117-119 ◽  
Author(s):  
M Kusunoki ◽  
K Kimura ◽  
K Nagatsuka ◽  
Y Isaka ◽  
O Uyama ◽  
...  
Keyword(s):  
Cerebrovascular Disease ◽  
Venous Blood ◽  
Second Phase ◽  
Cerebral Angiogram ◽  
Peripheral Venous Blood ◽  
Chronic Stage ◽  
Ischemic Cerebrovascular Disease ◽  
Carotid Arterial ◽  
Platelet Hyperaggregability ◽  
The Brain

SummaryPlatelet aggregation was studied in 24 patients in the chronic stage of ischemic cerebrovascular disease (CVD), with cerebral affluent and effluent blood, i.e., carotid arterial and internal jugular venous blood, and also with peripheral venous blood. Aggregation tests were performed at various final concentrations of sodium arachidonate (A.A.) and ADP. In 17 patients, not taking aspirin, platelet aggregability in jugular venous blood was significantly accentuated compared with that in arterial and peripheral venous blood. This tendency was more marked in the patients with cerebral artery stenosis and/or occlusion than in those with normal cerebral angiogram. In 7 patients taking 500 mg or more oral aspirin, aggregation differences across the brain were not observed and A.A. aggregation and the second phase of ADP aggregation were completely suppressed. These results suggest that a prophylactic administration of aspirin may be beneficial for patients in chronic stage of CVD.

Increased erythrocyte adhesiveness/aggregation in the peripheral venous blood of patients with ischaemic heart disease and an eventful course

2001 ◽  
Vol 56 (2) ◽  
pp. 121-126 ◽  
Author(s):  
Schlomo BERLINER ◽  
Rivka ROTSTEIN ◽  
Renato FUSMAN ◽  
Itzhak SHAPIRA ◽  
Ori ROGOWSKI ◽  
...  
Keyword(s):  
Heart Disease ◽  
Ischaemic Heart Disease ◽  
Venous Blood ◽  
Peripheral Venous Blood

scholarly journals The Perspective of Croatian Old Apple Cultivars in Extensive Farming for the Production of Functional Foods

Foods ◽  
2021 ◽  
Vol 10 (4) ◽  
pp. 708
Author(s):  
Boris Duralija ◽  
Predrag Putnik ◽  
Dora Brdar ◽  
Anica Bebek Markovinović ◽  
Sandra Zavadlav ◽  
...  
Keyword(s):  
Functional Foods ◽  
Geographical Location ◽  
Nutritional Composition ◽  
Climatic Conditions ◽  
Biologically Active ◽  
Biological Potential ◽  
Apple Cultivars ◽  
The Republic ◽  
Processed Form ◽  
Extensive Farming

The Republic of Croatia has a long tradition of fruit growing due to its geographical location, climatic conditions, and high quality of fruit crops, especially apple fruits. Apples can be used for the formulation of functional foods either in processed form (e.g., juice), or as a by-product (e.g., apple pomace). However, there is a growing demand for functional foods derived from ancient and traditional plant sources as they are recognized as a very valuable source of health-promoting bioactive ingredients. Similarly, old apple cultivars (Malus domestica Borkh.) are characterized by good morphological and pomological properties, less need for chemicals during cultivation and the higher share of biologically active compounds (BACs) with better sensory acceptability compared to commercial cultivars. However, their nutritional and biological potential is underestimated, as is their ability to be processed into functional food. The importance in preserving old apple cultivars can also be seen in their significance for improving the nutritional composition of other apple cultivars through innovative cultivation strategies, and therefore old local apple cultivars could be of great importance in future breeding programs.

scholarly journals Paleocene-Eocene volcanic segmentation of the Norwegian-Greenland seaway reorganized high-latitude ocean circulation

2021 ◽  
Vol 2 (1) ◽  
Author(s):  
Jussi Hovikoski ◽  
Michael B. W. Fyhn ◽  
Henrik Nøhr-Hansen ◽  
John R. Hopper ◽  
Steven Andrews ◽  
...  
Keyword(s):  
Ocean Circulation ◽  
High Latitude ◽  
Seismic Reflection ◽  
Arctic Region ◽  
Climatic Conditions ◽  
The Arctic ◽  
Early Eocene ◽  
Subaerial Exposure ◽  
Thermal Maximum ◽  
Volcanic Facies

AbstractThe paleoenvironmental and paleogeographic development of the Norwegian–Greenland seaway remains poorly understood, despite its importance for the oceanographic and climatic conditions of the Paleocene–Eocene greenhouse world. Here we present analyses of the sedimentological and paleontological characteristics of Paleocene–Eocene deposits (between 63 and 47 million years old) in northeast Greenland, and investigate key unconformities and volcanic facies observed through seismic reflection imaging in offshore basins. We identify Paleocene–Eocene uplift that culminated in widespread regression, volcanism, and subaerial exposure during the Ypresian. We reconstruct the paleogeography of the northeast Atlantic–Arctic region and propose that this uplift led to fragmentation of the Norwegian–Greenland seaway during this period. We suggest that the seaway became severely restricted between about 56 and 53 million years ago, effectively isolating the Arctic from the Atlantic ocean during the Paleocene–Eocene thermal maximum and the early Eocene.

scholarly journals High-time resolved radon-progeny measurements in the Arctic region (Svalbard Islands, Norway): results and potentialities

2017 ◽  
Author(s):  
Roberto Salzano ◽  
Antonello Pasini ◽  
Antonietta Ianniello ◽  
Mauro Mazzola ◽  
Rita Traversi ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Atmospheric Stability ◽  
Arctic Region ◽  
Climatic Conditions ◽  
The Arctic ◽  
Radon Emanation ◽  
Radon Progeny ◽  
Time Resolved ◽  
Scientific Challenge ◽  
The Arctic Region

Abstract. The estimation of radon progeny in the Arctic region represents a scientific challenge due to the required low limit of detection in consideration of the limited radon emanation associated with permafrost dynamics. This preliminary study highlighted, for the first time, the possibility to monitor radon progeny in the Arctic region with a higher time resolution. The composition of the radon progeny offered the opportunity to identify air masses dominated by long-range transport, in presence or not of near-constant radon progeny instead of long and short lived progenies. Furthermore, the different ratio between radon and thoron progenies evidenced the contributions of local emissions and atmospheric stability. Two different emanation periods were defined in accordance to the permafrost dynamics at the ground and several accumulation windows were recognized coherently to the meteo-climatic conditions occurring at the study site.

Sensitive detection of circulating hepatocellular carcinoma cells in peripheral venous blood

Cancer ◽  
1995 ◽  
Vol 75 (9) ◽  
pp. 2214-2219 ◽  
Author(s):  
Toshiki Komeda ◽  
Yoshihiro Fukuda ◽  
Takehiro Sando ◽  
Ryuichi Kita ◽  
Motonobu Furukawa ◽  
...  
Keyword(s):  
Hepatocellular Carcinoma ◽  
Venous Blood ◽  
Carcinoma Cells ◽  
Sensitive Detection ◽  
Hepatocellular Carcinoma Cells ◽  
Peripheral Venous Blood

scholarly journals Sea-ice induced growth decline in Arctic shrubs

2017 ◽  
Vol 13 (8) ◽  
pp. 20170122 ◽  
Author(s):  
Mads Forchhammer
Keyword(s):  
Sea Ice ◽  
Ring Width ◽  
Plant Productivity ◽  
Climatic Conditions ◽  
Arctic Sea Ice ◽  
Annual Growth ◽  
The Arctic ◽  
Growth Time ◽  
Sea Ice Extent ◽  
Negative Effect

Measures of increased tundra plant productivity have been associated with the accelerating retreat of the Arctic sea-ice. Emerging studies document opposite effects, advocating for a more complex relationship between the shrinking sea-ice and terrestrial plant productivity. I introduce an autoregressive plant growth model integrating effects of biological and climatic conditions for analysing individual ring-width growth time series. Using 128 specimens of Salix arctica , S. glauca and Betula nana sampled across Greenland to Svalbard, an overall negative effect of the retreating June sea-ice extent was found on the annual growth. The negative effect of the retreating June sea-ice was observed for younger individuals with large annual growth allocations and with little or no trade-off between previous and current year's growth.

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