scholarly journals Old and New Biomarkers Associated with Endothelial Dysfunction in Chronic Hyperglycemia

2021 ◽  
Vol 2021 ◽  
pp. 1-13
Author(s):  
Maria Pompea Antonia Baldassarre ◽  
Caterina Pipino ◽  
Assunta Pandolfi ◽  
Agostino Consoli ◽  
Natalia Di Pietro ◽  
...  
Keyword(s):  
Endothelial Dysfunction ◽  
Treatment Strategies ◽  
Vascular Damage ◽  
Assessment Tools ◽  
Cardiovascular Risk Assessment ◽  
Chronic Hyperglycemia ◽  
Risk Assessment Tools ◽  
New Biomarkers ◽  
Near Future

Chronic hyperglycemia and vascular damage are strictly related. Biomarkers of vascular damage have been intensively studied in the recent years in the quest of reliable cardiovascular risk assessment tools able to facilitate risk stratification and early detection of vascular impairment. The present study is a narrative review with the aim of revising the available evidence on current and novel markers of hyperglycemia-induced vascular damage. After a discussion of classic tools used to investigate endothelial dysfunction, we provide an in-depth description of novel circulating biomarkers (chemokines, extracellular vesicles, and epigenetic and metabolomic biomarkers). Appropriate use of a single as well as a cluster of the discussed biomarkers might enable in a near future (a) the prompt identification of targeted and customized treatment strategies and (b) the follow-up of cardiovascular treatment efficacy over time in clinical research and/or in clinical practice.

Cardiovascular risk assessment tools in non-Western populations

2018 ◽  
Vol 272 ◽  
pp. 331-332
Author(s):  
Gary Tse ◽  
Leonardo Roever ◽  
Martin C.S. Wong ◽  
Tong Liu
Keyword(s):  
Risk Assessment ◽  
Cardiovascular Risk ◽  
Assessment Tools ◽  
Cardiovascular Risk Assessment ◽  
Risk Assessment Tools

scholarly journals Assessing Protective Factors for Adolescent Offending: A Conceptually Informed Examination of the SAVRY and YLS/CMI

Assessment ◽  
2018 ◽  
Vol 27 (5) ◽  
pp. 959-975 ◽  
Author(s):  
Jodi L. Viljoen ◽  
Aisha K. Bhanwer ◽  
Catherine S. Shaffer ◽  
Kevin S. Douglas
Keyword(s):  
Protective Factors ◽  
Area Under The Curve ◽  
Assessment Tools ◽  
Violence Risk ◽  
Protective Effects ◽  
Adolescent Risk ◽  
Risk Assessment Tools ◽  
Relevant Role ◽  
Research Assistants

Although the Structured Assessment of Violence Risk in Youth (SAVRY) and the Youth Level of Service/Case Management Inventory (YLS/CMI) are among the most widely used adolescent risk assessment tools, they conceptualize and measure strengths differently. As such, in this study, we compared the predictive validity of SAVRY Protective Total and YLS/CMI Strength Total, and tested conceptual models of how these measures operate (i.e., risk vs. protective effects, direct vs. buffering effects, causal models). Research assistants conducted 624 risk assessments with 156 youth on probation. They rated protective factors at baseline, and again at 3-, 6-, 9-, and 12-month follow-up periods. The SAVRY Protective Total and YLS/CMI Strength Total inversely predicted any charges in the subsequent 2 years (area under the curve scores = 0.61 and 0.60, respectively, p < .05). Furthermore, when adolescents’ protective total scores increased, their self-reported violence decreased, thus providing evidence that these factors might play a causally relevant role in reducing violence. However, protective factors did not provide incremental validity over risk factors. In addition, because these measures are brief and use a dichotomous rating system, they primarily captured deficits in protective factors (i.e., low scores). This suggests a need for more comprehensive measures.

Cardiovascular risk assessment tools: A scoping review

2019 ◽  
Vol 32 (6) ◽  
pp. 540-559 ◽  
Author(s):  
Jennifer Sacramento-Pacheco ◽  
Gonzalo Duarte-Clíments ◽  
Juan Gómez-Salgado ◽  
Macarena Romero-Martín ◽  
María Begoña Sánchez-Gómez
Keyword(s):  
Risk Assessment ◽  
Cardiovascular Risk ◽  
Scoping Review ◽  
Assessment Tools ◽  
Cardiovascular Risk Assessment ◽  
Risk Assessment Tools

Managing colorectal cancer patients in the COVID-19 era: international discussion on the role of precision medicine in triaging patients

2020 ◽  
Keyword(s):  
Colorectal Cancer ◽  
Precision Medicine ◽  
Cancer Patients ◽  
Treatment Strategies ◽  
Assessment Tools ◽  
Cancer Management ◽  
Appropriate Treatment ◽  
Risk Assessment Tools ◽  
Coronavirus Infection ◽  
Colorectal Cancer Patients

The global COVID-19 pandemic has had a serious impact on cancer treatment. Oncologists must now incorporate the risks of coronavirus infection into their decision making. Precision medicine tools identifying the most appropriate treatment strategies for individual patients has never been more important Two recent articles published in the journal Colorectal Cancer address this issue from the US and Latin America perspective and provide considerations for optimizing the treatment of patients with colorectal cancer whilst minimizing the risk of coronavirus infection. This video brings together the authors of both publications to discuss their articles and provide their own personal experiences using risk-assessment tools such as Immunoscore in triaging colorectal cancer patients. This international discussion provides oncologists and other healthcare professionals with valuable insights into the multidisciplinary approaches to colorectal cancer management that are needed on the COVID-19 era.

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