Abstract 1455:In vivocirculating tumor cells in blood, lymph and cerebrospinal fluid: dynamic cross-correlations and amplification for cancer diagnosis.

Author(s):  
Ekaterina I. Galanzha
1995 ◽  
Vol 52 (8) ◽  
pp. 783-789 ◽  
Author(s):  
J. Malm ◽  
B. Kristensen ◽  
T. Karlsson ◽  
M. Fagerlund ◽  
J. Elfverson ◽  
...  

2014 ◽  
Vol 10 (2) ◽  
pp. E374-E378 ◽  
Author(s):  
Matteo Martinoni ◽  
Francesco Toni ◽  
Mariella Lefosse ◽  
Eugenio Pozzati ◽  
Anna Federica Marliani ◽  
...  

Abstract BACKGROUND AND IMPORTANCE: Arachnoid cysts within the fourth ventricle have rarely been reported in the literature. Different procedures have been performed to restore a normal cerebrospinal fluid dynamic or pressure, including shunting and partial or complete excision of the cyst by open microsurgery. Cerebrospinal fluid shunts give only partial improvement of symptoms and are prone to malfunctions. The microsurgical excision of the cyst seems to offer the best chance of success. CLINICAL PRESENTATION: We report the case of a fourth ventricle arachnoid cyst successfully treated with a complete endoscopic cerebral procedure via the third ventricle. CONCLUSION: Endoscopic fenestration of fourth ventricle arachnoid cysts may be considered an effective neurosurgical treatment.


2015 ◽  
Vol 12 (Suppl 1) ◽  
pp. P11
Author(s):  
Claudia Craven ◽  
Neekhil A Patel ◽  
Akbar A Khan ◽  
Simon D Thompson ◽  
Edward W Dyson ◽  
...  

2020 ◽  
Vol 13 ◽  
pp. 251686572090405 ◽  
Author(s):  
Seyed Mohammad Kazem Aghamir ◽  
Ramin Heshmat ◽  
Mehdi Ebrahimi ◽  
Fatemeh Khatami

Blood test is a kind of liquid biopsy that checks cancer cells or cancer nucleic acids circulating freely from cells in the blood. A liquid biopsy may be used to distinguish cancer at early stages and it could be a game-changer for both cancer diagnosis and prognosis strategies. Liquid biopsy tests consider several tumor components, such as DNA, RNA, proteins, and the tiny vesicles originating from tumor cells. Actually, liquid biopsy signifies the genetic alterations of tumors through nucleic acids or cells in various body fluids, including blood, urine, cerebrospinal fluid, or saliva in a noninvasive manner. In this review, we present an overall description of liquid biopsy in which circulating tumor cells, cell-free nucleic acids, exosomes, and extrachromosomal circular DNA are included.


2016 ◽  
Vol 12 (6) ◽  
pp. 5080-5084 ◽  
Author(s):  
Yuan Lv ◽  
Ning Mu ◽  
Chunhua Ma ◽  
Rong Jiang ◽  
Qiaoli Wu ◽  
...  

1995 ◽  
Vol 53 (2) ◽  
pp. 218-226 ◽  
Author(s):  
Maria José Sá ◽  
Rui Vaz ◽  
Celso Cruz

The main objective of this retrospective review of clinical and cerebrospinal fluid (CSF) data from 41 patients with intracranial tumors diagnosed between 1975 and 1989, is to report the role that the finding of neoplastic cells in CSF plays, specially when cerebral CT-scanning and MRI were not currently done. Another objective is to study the CSF proteic abnormalities in cerebral tumors. CSF cell count, cytomorphologic pictures obtained after sedimentation and protein findings are described. Tumor cells were seen in 12 cases (29%): medulloblastomas - 6, meningeal carcinomatosis - 3, multiforme glioblastoma - 1, ependymoma -1, cerebral metastasis -1; in two cases it was an unexpected finding. We noticed that tumoral localization next to the ventricles favoured cell exfoliation. Although pleocytosis was rare and uncorrelated with the presence of neoplastic cells, pathological cytomorphologic pictures appeared in most of the cases including all "positive" ones. Our results stress that the appearance of neoplastic cells in CSF remains helpful specially when it is an unexpected finding.


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