Typical Features of Calciphylaxis in a Patient with End-Stage Renal Failure, Diabetes mellitus and Oral Anticoagulation

Dermatology ◽  
2000 ◽  
Vol 200 (4) ◽  
pp. 356-359 ◽  
Author(s):  
M. Streit ◽  
B.E. Paredes ◽  
S. Rüegger ◽  
C.U. Brand
2021 ◽  
pp. 175319342098187
Author(s):  
Matthew Wyman ◽  
Dallan Dargan ◽  
Jennifer Caddick ◽  
Victoria Giblin

We present 210 patients with hand osteomyelitis in 246 rays over 12 years, including detailed analysis of 29 patients in this cohort with digital artery calcification evident on plain X-ray. Overall 71 patients had diabetes mellitus and/or end-stage renal failure, including 28 of 29 patients with calcification. In the calcification group, 17 patients had ipsilateral arteriovenous fistulae, five had steal syndrome and 15 had digital ulceration or skin necrosis. Compared with 181 controls, patients with calcification had more affected bones, polymicrobial infections, surgical procedures, phalanges and digits amputated and had higher mortality at 1 year (12 of 29) and 5 years (20 of 29), as a result of comorbidities. Absence of calcification in 43 patients with diabetes and/or end-stage renal failure was associated with better outcomes on all the above parameters. Early amputation to maximize disease-free survival may be appropriate for patients with hand osteomyelitis and arterial calcification. Level of evidence: IV


2004 ◽  
Vol 22 (Suppl. 2) ◽  
pp. S223
Author(s):  
I. Moyssakis ◽  
D. Doulgerakis ◽  
N. Tentolouris ◽  
D. Papadopoulos ◽  
E. Gialafos ◽  
...  

1997 ◽  
Vol 81 (2) ◽  
pp. 627-633 ◽  
Author(s):  
Isao Fukunishi

This study examined the clinical characteristics including stress-related factors of eating disorders in a sample of 312 diabetic patients with end-stage renal failure. The prevalence rate of bulimia nervosa was 5.1% (16 of 312 patients). The 16 patients with bulimia nervosa were 8 men and 8 women over 58 years old. Looking at the subjects by cause of end-stage renal failure, those with diabetes mellitus exhibited significantly higher prevalence rate of bulimia nervosa than two nondiabetic groups (diabetes 10%; nephritis 1.6%; others 1.9%). As for the association of bulimia nervosa and stress-related factors, end-stage renal failure patients with diabetes who exhibited bulimia nervosa showed significantly higher scores on a measure of alexithymia. These results suggest that, when liaison psychiatrists see diabetic patients with end-stage renal failure who exhibit bulimia nervosa, they should pay close attention to stress-related symptoms including alexithymia.


2013 ◽  
Vol 2013 ◽  
pp. 1-6 ◽  
Author(s):  
Stephen E. Thwaites ◽  
Vincent W. T. Lam ◽  
Jinna Yao ◽  
Kathy Kable ◽  
Lillian Jenkins ◽  
...  

Introduction. Simultaneous pancreas and kidney (SPK) transplantation is performed to restore normoglycaemia and renal function in patients with Type I diabetes mellitus and end-stage renal failure. We aimed to evaluate the impact of major postoperative complications to patient and graft survival outcomes. Method. Using a prospectively collected database over a 10-year period, major postoperative complications requiring return to operating theatre as well as patient and graft survival outcomes were analysed retrospectively. Results. Between January 2001 and May 2010, 165 patients underwent first-time SPK transplantation. Median age of recipients was 39.8 years (range, 16.9–53.2). Enteric drainage was used in 149 patients, and bladder drainage was used in 16. Median follow-up time was 5.2 years (range 1.1–10.3). Fifty-six patients (34%) returned to operating theatre at least once. Pancreatic allograft loss secondary to vascular thrombosis occurred in 12 patients (7%), and 2 patients (1.2%) required transplant pancreatectomy due to debilitating pancreatic enzyme leaks. At 1 and 5 years, patient survival was 98% and 94%; pancreas graft survival, 86% and 77%; kidney graft survival 96% and 89%, respectively. Conclusion. SPK is a safe and effective treatment for Type I diabetes mellitus and end-stage renal failure although surgical reintervention is required in approximately one-third of patients. Preventing vascular thrombosis remains a major challenge.


2015 ◽  
Vol 18 (2) ◽  
pp. 89-95
Author(s):  
Yulia Alexandrovna Krupinova ◽  
Sergei Andreevich Martinov ◽  
Alexandra Michailovna Glazunova ◽  
Evgeny Vladimirovich Tarasov

This article describes the clinical case of a patient with early development of terminal complications of type 1 diabetes with chronic decompensated carbohydrate metabolism. For 1 year, the patient was treated with hemodialysis and she subsequently underwent successful kidney transplantation.


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