Hemodynamics at Rest and during Exercise in 222 Patients with Coronary Heart Disease before and after Aorto-Coronary Bypass Surgery

Patients (111 males) with coronary heart disease (CHD) and angina, II-III functional class, accompanied by arterial hypertension (AH), I-III degree, in 77 % of cases (mean age was 62.00.76 years) were examined prior to coronary bypass surgery. The patients were divided into two groups: group 1 consisted of 56 nonsmoking patients (112 upper extremities) and group 2 - 55 smoking patients (110 upper extremities) with the experience of smoking being 331.6 years on average. The thumb of both the right and left hand was tested for peripheral microcirculatory blood flow (MBF) by using a laser-Doppler flowmetry method (LDF). This quantitative method was developed at our clinic to assess the adequacy of collateral circulation in the hand. The method compares MBF provided by the ulnar artery, with the radial artery occluded, with the background level. Some features of various clinical parameters in the group of smokers suffering from coronary artery disease were analyzed in comparison with those of non-smokers. Significant differences were found in the indicators of lipid profile: increased levels of total cholesterol and low-density lipoprotein (LDL) against the background of low high-density lipoprotein (HDL) in the group of smoking patients. We found out that the smokers had to apply for surgical treatment by 7 years (on average) earlier; they had a significantly greater number of heart attacks and showed the lowest body mass index (BMI). The LDF test helped to establish that smoking in patients with CHD enhances the endothelial dysfunction, while significantly reducing the reactivity of the microvascular bed under the influence of hyperemic stimulus. Sampling the radial artery for coronary artery bypass grafting in smokers tended to give negative results.

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Dynamics of parameters of oxidative stress in blood of ischemic heart disease patients before and after coronary bypass surgery

Bulletin of Siberian Medicine ◽

10.20538/1682-0363-2012-4-13-17 ◽

2012 ◽

Vol 11 (4) ◽

pp. 13-17

Author(s):

N. L. Vorontsova ◽

M. V. Bogdanov ◽

А. S. Golovkin ◽

R. A. Mukhamadiyarov ◽

Ye. V. Grigoriyev ◽

...

Keyword(s):

Oxidative Stress ◽

Heart Disease ◽

Ischemic Heart Disease ◽

Bypass Surgery ◽

Coronary Bypass ◽

Ischemic Heart ◽

Coronary Bypass Surgery ◽

Before And After

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Predoperatsionnaya terapiya statinamiu patsientov s ishemicheskoy bolezn'yu serdtsa

Cardiosomatics ◽

10.26442/cs44972 ◽

2011 ◽

Vol 2 (1) ◽

pp. 51-54

Author(s):

Ol'ga Leonidovna Barbarash ◽

Yuliya Vyacheslavovna Bayrakova ◽

Evgeniya Mikhaylovna Kurguzova

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Statin Therapy ◽

Bypass Surgery ◽

Heart Diseases ◽

Coronary Bypass ◽

Ischemic Heart ◽

Coronary Bypass Surgery ◽

Ischemic Heart Diseases

Summary. The need for statins in patients with acute and chronic forms of coronary heart disease is now beyond doubt. However, there is still a view that from the perspective of safety it is necessary to cancel statins before a surgery and reinstitute them after a surgery. This review examines the feasibility and safety of preoperative statin therapy in patients with ischemic heart diseases before planned coronary bypass surgery.

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DIABETUS MELLITUS AND SURGICAL TREATMENT OF CORONARY HEART DISEASE

Annals of the Russian academy of medical sciences ◽

10.15690/vramn.v67i1.104 ◽

2012 ◽

Vol 67 (1) ◽

pp. 14-19 ◽

Cited By ~ 4

Author(s):

R. S. Akchurin ◽

E. E. Vlasova ◽

K. V. Mershin

Keyword(s):

Diabetes Mellitus ◽

Coronary Heart Disease ◽

Heart Disease ◽

Surgical Treatment ◽

Bypass Surgery ◽

Coronary Bypass ◽

Coronary Bypass Surgery ◽

Diabetic Patients ◽

Cardio Vascular

Nearly 40-year experience of surgical treatment of coronary heart disease testifies to higher coronary heart disease (CHD) morbidity and mortality rates among diabetes mellitus patients in comparison to non-diabetic patients. At the same time, comparative study of CHD treatment methods efficacy in diabetes mellitus patients has shown that surgery is preferred to angioplasty, especially in the most severe cases – in presence of coronary occlusion, insulin-dependent diabetes and left-ventricle dysfunction. More inferior results of coronary bypass surgery in diabetic patients in comaparison to non-diabetic were conditional on a more pronounced arterial calcinosis and diffuse distal arterial involvement, as well as more severe aortal ateromatosis, flebopathy and more often wound infection occurrence. In the department of cardio-vascular surgery in Russian cardiologic scientific productive complex a quarter of all patients waiting for the coronary bypass surgery are diabetic. Selection algorithm, preoperation preparation, peculiarities of surgical technique and principles of postoperative supervision of these patients were specially designed. With adequate preparation, remission of diabetes and use of microsurgery, postoperative prognosis for these patients (both stratified and real) is comparative to that for the main group of patients. One-year follow up after the bypass surgery data testifies to the low difference in autovenous and autoarterial shunt patency in diabetic and non-diabetic patients. Long-term (10 years) survival rate is significantly lower in the group of diabetic patients. Proposed cardioprotective postoperative strategy is designed to improve both short and long-term efficacy of surgical revascularization in CHD patients with concomitant diabetes mellitus.

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Prevalence of comorbidities and their influence on complications and outcomes of coronary bypass surgery for coronary heart disease in gender perspective

CARDIOVASCULAR THERAPY AND PREVENTION ◽

10.15829/1728-8800-2016-2-32-37 ◽

2016 ◽

Vol 15 (2) ◽

pp. 32-37

Author(s):

E. B. Klester ◽

O. A. Ivanov ◽

D. S. Budnev ◽

V. A. Elykomov

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Bypass Surgery ◽

Coronary Bypass ◽

Coronary Bypass Surgery ◽

Gender Perspective

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Impact of aorto-coronary bypass surgery on quality of life and prognosis in patients with coronary heart disease

Vrach ◽

10.29296/25877305-2021-08-15 ◽

2021 ◽

Vol 32 (8) ◽

pp. 79-83

Author(s):

D. Dedov ◽

I. Evtyukhin

Keyword(s):

Quality Of Life ◽

Coronary Heart Disease ◽

Heart Disease ◽

Bypass Surgery ◽

Coronary Bypass ◽

Coronary Bypass Surgery

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The results of complex surgical treatment of patients with coronary heart disease

Clinical Medicine (Russian Journal) ◽

10.30629/0023-2149-2020-98-11-12-766-771 ◽

2021 ◽

Vol 98 (11-12) ◽

pp. 766-771

Author(s):

Yu. I. Shevchenko ◽

F. A. Zainiddinov ◽

G. G. Borshchev ◽

D. S. Ulbashev ◽

I. A. Musaev

Keyword(s):

Quality Of Life ◽

Coronary Heart Disease ◽

Heart Disease ◽

Surgical Treatment ◽

Bypass Surgery ◽

Myocardial Revascularization ◽

Coronary Bypass ◽

Coronary Bypass Surgery ◽

Complication Rates

Coronary heart disease (CHD) remains one of the main causes of morbidity, early disability and mortality in the adult population, despite significant achievements in the diagnosis and correction of coronary blood flow disorders. An undoubted achievement at the present stage is the improvement of conservative and X-ray endovascular methods of treatment, but it has led to an increase in the number of patients with diffuse coronary disorders. We have developed a method of combined treatment of coronary heart disease through direct myocardial revascularization (CABG) in combination with the program YurLeon III, which allows to improve the results in this group of patients.Aim. To compare the immediate and end results of combined surgery (CABG + YurLeon III) with isolated direct myocardial revascularization. Material and methods. The study included 730 patients diagnosed with coronary heart disease, exertional angina pectoris (stages III, IV), who underwent surgical revascularization of the myocardium in Pirogov National Medical and Surgical Center, Russian Federation. There were 445 men (60.96%) and 285 (39.04%) women, aged 50 to 73. 580 patients underwent coronary bypass surgery (CABG). 150 patients underwent coronary bypass surgery supplemented with indirect revascularization of YurLeon III (CABG + YurLeon III). Patients underwent gated-SPECT, echocardiography, computer tomography, and quality of life evaluation with the use of SF-36 questionnaire. Results. At the intraoperative stage in the early postoperative period, there were no significant differences in complication rates between t two groups (p > 0.05). 1 year after surgery, statistically significant differences in EF were noted: 55.10 ± 5.98% (after CABG + YurLeon III), 50.07 ± 6.54% (after CABG)(p < 0.05); perfusion defect:18.56 ± 9.56%(after CABG) and 8.38 ± 5.79% (after CABG + YurLeon III) (p < 0.05); quality of life: increased in PF, BP, and RE indicators — by 39, 64, and 30 points (after CABG + YurLeon III); by 30, 29, and 26 points (after CABG) (p < 0.05). Conclusion. Coronary bypass surgery, supplemented with YurLeon III, is an effective and safe method of surgical treatment of patients with coronary heart disease, especially with diffuse disorders of the coronary arteries. It allows to additionally supply myocardium with the blood.

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Comparative analysis of the characteristics of patients with coronary heart disease of middle and older age with different dynamics of cognitive functioning during rehabilitation after coronary bypass surgery

Vestnik of Saint Petersburg University Psychology ◽

10.21638/spbu16.2020.403 ◽

2020 ◽

Vol 10 (4) ◽

pp. 417-427

Author(s):

Olga Grigoreva ◽

◽

Daria Eremina ◽

Keyword(s):

Coronary Heart Disease ◽

Heart Disease ◽

Coronary Artery ◽

Cognitive Functioning ◽

Bypass Surgery ◽

Block Design ◽

Coronary Bypass ◽

Diagnostic Methods ◽

Coronary Bypass Surgery ◽

History Of

For an in-depth study of the main clinical, psychosocial and emotional-personal characteristics of patients with coronary heart disease with different dynamics (improvement and deterioration) of cognitive functioning after coronary bypass surgery, a study was conducted on the basis of the Federal State Medical Research Center named after V. A. Almazova (St. Petersburg). The study involved 51 patients: 24 elderly (60–74 years old) and 27 middleaged patients (45–59 years old). The study was carried out in two stages: the 1st stage — immediately before coronary artery bypass grafting (1–2 days before the operation), the 2nd stage — 7–10 days after the operation. We used a clinical psychology interview and following psycho diagnostic methods: Integrative anxiety test (IАT), Toronto alexithymic scale (TAS), Trail Making Test (TMT), Subtests of “Similarities” and “The Block Design Tests (Kohs)” from the Veksler Scale for the Study of the Intelligence of Adults (WAIS), “10 words”; “Remembering stories”, “Simple analogies”, Test of visual retention A. Benton, Interference Stroop Task. According to the data obtained, elderly patients with cognitive impairment differ: not following a diet before hospitalization; lack of physical activity before hospitalization; the presence in the history of obesity of one degree or another; a large number of affected arteries (including trunks); more burdened by heredity in CVD in the male line. At the same time, middle-aged patients with a deterioration in the dynamics of cognitive functioning are distinguished by a large number of cigarettes smoked per day; damage to the left coronary artery, the presence in the history of chronic bronchitis; pronounced phobic component of personal anxiety.

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