Role of Hormonal Disturbances in Uremic Growth Failure

2015 ◽  
pp. 119-129 ◽  
Author(s):  
O. Mehls ◽  
E. Ritz ◽  
G. Gilli ◽  
V. Heinrich
Keyword(s):  
Growth Failure

Addressing the growth failure of the oil economies: The role of financial development

2007 ◽  
Vol 46 (5) ◽  
pp. 726-740 ◽  
Author(s):  
Masoud Nili ◽  
Mahdi Rastad
Keyword(s):  
Financial Development ◽  
Growth Failure

scholarly journals Growth and body composition in children with chronic kidney disease

2007 ◽  
Vol 97 (2) ◽  
pp. 232-238 ◽  
Author(s):  
R. Rashid ◽  
E. Neill ◽  
H. Maxwell ◽  
S. F. Ahmed
Keyword(s):  
Chronic Kidney Disease ◽  
Body Composition ◽  
Kidney Disease ◽  
Growth Failure ◽  
Potential Effect ◽  
Complex Problem ◽  
Physiological Mechanisms ◽  
Growth And Nutrition

Growth failure is a common yet complex problem of childhood chronic kidney disease caused by multiple factors encountered due to the primary disease or secondary to the renal impairment. This review seeks to describe the various patho-physiological mechanisms contributing to growth failure in the various stages of childhood with particular emphasis on nutritional problems and endocrine dysfunction encountered whilst managing these children. In addition, we shall examine the role of body composition in chronic kidney disease, their relationship with growth and nutrition and the potential effect of abnormalities in fat mass and lean mass on long-term morbidity and mortality.

Rethinking Growth Failure in Alagille Syndrome: The Role of Dietary Intake and Steatorrhea

2002 ◽  
Vol 35 (4) ◽  
pp. 495-502 ◽  
Author(s):  
Alisha J. Rovner ◽  
Joan I. Schall ◽  
Abbas F. Jawad ◽  
David A. Piccoli ◽  
Virginia A. Stallings ◽  
...  
Keyword(s):  
Dietary Intake ◽  
Growth Failure ◽  
Alagille Syndrome

Linear growth failure of Ethiopian children : The role of protein, zinc and mycotoxin intake

2020 ◽  
Author(s):  
Masresha Tessema Anegago
Keyword(s):  
Linear Growth ◽  
Growth Failure

scholarly journals Treatment of Inflammatory Bowel Disease in Children

1990 ◽  
Vol 4 (7) ◽  
pp. 404-406 ◽  
Author(s):  
D Grant Gall
Keyword(s):  
Ulcerative Colitis ◽  
Inflammatory Bowel Disease ◽  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Enteral Nutrition ◽  
Bowel Disease ◽  
Growth Failure ◽  
Nutritional Therapy ◽  
Inflammatory Bowel

As no curative therapy exists, supportive measures play an important role in the management of patients with inflammatory bowel disease (IBO). Aminosalicylic acid (ASA) compounds and corticosteroids remain the mainstay of medical therapy. Aminosalicylates are recommended for therapy of mild to moderate active ulcerative colitis and for the maintenance of remission in ulcerative colitis. The role of 5-ASA preparations in Crohn's disease is less clear. In granulomatous colitis, 5-ASA therapy is recommended. With the development of new delivery systems, the role for 5-ASA in the treatment of small bowel Crohn's disease is under investigation. Prednisone remains the drug of choice in severe ulcerative colitis and active Crohn's disease. The role of immunosuppressive drugs in pediatric patients is unclear. Nutritional therapy has been an important advance in the treatment of children with Crohn's disease, especially those with growth failure. Nutritional therapy can consist of combined total parenteral and enteral nutrition or enteral nutrition alone. An initial period of total parenteral nutrition followed by a six to eight week course of enteral therapy with a semisynthetic diet has been shown to be effective in the management of patients with severe active disease and growth failure.

scholarly journals An intragenic deletion within CTNNA2 intron 7 in a boy with short stature and speech delay: A case report

2017 ◽  
Vol 5 ◽  
pp. 2050313X1769396
Author(s):  
Valeria Paganelli ◽  
Mara Giordano ◽  
Cristina Meazza ◽  
Lucia Schena ◽  
Mauro Bozzola
Keyword(s):  
Short Stature ◽  
Expressive Language ◽  
Growth Failure ◽  
Chromosome 2 ◽  
Mild Mental Retardation ◽  
Speech Delay ◽  
Intragenic Deletion ◽  
Language Problems ◽  
Molecular Karyotype

Background/Objectives: Deletions on the short arm of chromosome 2 at bands p11 and p12 have been detected in association with short stature, mild mental retardation and speech delay. Results: We describe a 4 year-old boy with some facial dysmorphic traits, congenital malformations and pre- and post-natal growth failure. He also presented marked expressive language problems. The molecular karyotype revealed a 108 Kb deletion within the seventh intron of the CTNNA2 gene at 2p11.2-p12. We observed that some features (short stature, facial dysmorphisms and speech delay) were present in our patient and in patients carrying much larger overlapping deletions. Conclusions: The description of this small intragenic rearrangement might help to elucidate the role of the single genes included in the 2p11.2-p12 critical region.

Role of Growth Hormone in Growth Failure of Uraemia -Perspectives for Application of Recombinant Growth Hormone

2008 ◽  
Vol 77 ◽  
pp. 118-126
Author(s):  
O. MEHLS ◽  
E. RITZ ◽  
E.B. HUNZIKER ◽  
B. TÖNSHOFF ◽  
U. HEINRICH
Keyword(s):  
Growth Hormone ◽  
Growth Failure ◽  
Recombinant Growth Hormone

scholarly journals Autosomal Recessive Polycystic Kidney Disease—The Clinical Aspects and Diagnostic Challenges

2020 ◽  
Author(s):  
Dorota Wicher ◽  
Łukasz Obrycki ◽  
Irena Jankowska
Keyword(s):  
Genetic Testing ◽  
Kidney Disease ◽  
Polycystic Kidney Disease ◽  
Autosomal Recessive ◽  
Multidisciplinary Approach ◽  
Growth Failure ◽  
Clinical Aspects ◽  
Polycystic Kidney ◽  
Clinical Criteria

AbstractAutosomal recessive polycystic kidney disease (ARPKD) is one of the most common ciliopathies with kidney (nephromegaly, hypertension, renal dysfunction) and liver involvement (congenital hepatic fibrosis, dilated bile ducts). Clinical features also include growth failure and neurocognitive impairment. Plurality of clinical aspects requires multidisciplinary approach to treatment and care of patients. Until recently, diagnosis was based on clinical criteria. Results of genetic testing show the molecular basis of polycystic kidneys disease is heterogeneous, and differential diagnosis is essential. The aim of the article is to discuss the role of genetic testing and its difficulties in diagnostics of ARPKD in children.

Role of Interleukin-6 in Growth Failure: An Animal Model

2002 ◽  
Vol 58 (1) ◽  
pp. 24-27 ◽  
Author(s):  
Fabrizio De Benedetti ◽  
Cristina Meazza ◽  
Alberto Martini
Keyword(s):  
Animal Model ◽  
Interleukin 6 ◽  
Growth Failure

Growth failure in adolescents: etiology, the role of pubertal timing and most useful criteria for diagnostic workup

2016 ◽  
Vol 29 (4) ◽  
Author(s):  
Susanne E. Stalman ◽  
Ilse Hellinga ◽  
Jan M. Wit ◽  
Raoul C.M. Hennekam ◽  
Gerdine A. Kamp ◽  
...  
Keyword(s):  
Pubertal Timing ◽  
Diagnostic Testing ◽  
Growth Failure ◽  
Tanner Stage ◽  
Diagnostic Workup ◽  
Growth Monitoring ◽  
Diagnostic Protocol ◽  
Pubertal Delay ◽  
Constitutional Delay

AbstractThe aim of the study was to evaluate the etiology, the role of pubertal timing and most useful criteria for diagnostic workup in adolescents with growth failure.Adolescents (n=182) aged 10.0–18.0 years underwent a standardized diagnostic protocol. Constitutional delay of growth and puberty (CDGP) was defined as late pubertal onset or a Tanner stage less than –2 SDS. Dutch and Finnish criteria for growth monitoring were retrospectively assessed.In 13 children (7.1%) a specific diagnosis could be established. CDGP was diagnosed in 10% of patients aged ≥13 (girls) or ≥14 years (boys). Sensitivity to detect pathologic causes was 85% and 62% for, respectively Dutch and Finnish criteria for growth monitoring as used in younger children, but specificity was low (55%–59%).In adolescents, pathological causes for growth failure and pubertal delay are common, and we recommend a combination of height SDS, distance to THSDS and growth deflection for deciding on further diagnostic testing.

Sign in / Sign up

Export Citation Format

Share Document